| POSITIVE SIDE |
ANNOTATION |
*
* |
NEGATIVE SIDE |
ANNOTATION |
| IC1+ (212 genes) |
1: GO: Molecular Function:microtubule binding
2: GO: Biological Process:chromosome segregation
3: GO: Cellular Component:spindle
4: Human Phenotype:Cortical gyral simplification
5: Mouse Phenotype:abnormal mitosis
6: Domain:Kinesin-like fam
7: Pathway:Cell Cycle, Mitotic
9: Interaction:CDK1 interactions
11: Transcription Factor Binding Site:V$NFY Q6
12: Gene Family:Kinesins|Pleckstrin homology domain containing
13: Coexpression:The 'Cervical Cancer Proliferation Cluster' (CCPC): genes whose expression in cervical carcinoma positively correlates with that of the HPV E6 and E7 oncogenes; they are also differentially expressed according to disease outcome.
14: Coexpression Atlas:alpha beta T cells, T.DPbl.Th, 4+ 8+ TCR-/lo FSChi, Thymus, avg-3
18: Disease:Invasive Ductal Breast Carcinoma
|
*
* |
IC1- (5 genes) |
none |
| IC2+ (291 genes) |
1: GO: Molecular Function:DNA-dependent ATPase activity
2: GO: Biological Process:DNA replication
3: GO: Cellular Component:chromosomal region
4: Human Phenotype:Tracheoesophageal fistula
5: Mouse Phenotype:chromosomal instability
7: Pathway:Cell Cycle, Mitotic
9: Interaction:PCNA interactions
11: Transcription Factor Binding Site:V$E2F Q6
12: Gene Family:Fanconi anemia complementation groups
13: Coexpression:Genes up-regulated in MCF7 cells (breast cancer) at 24 h of estradiol [PubChemID=5757] treatment.
14: Coexpression Atlas:alpha beta T cells, T.ISP.Th, 4- 8+ TCR-/lo 24hi, Thymus, avg-3
18: Disease:FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)
|
*
* |
IC2- (10 genes) |
none |
| IC3+ (131 genes) |
14: Coexpression Atlas:26Dp SubClass 26Dp 3 Top 500 All
|
*
* |
--- |
--- |
| IC4+ (372 genes) |
1: GO: Molecular Function:oxidoreductase activity, acting on NAD(P)H
2: GO: Biological Process:respiratory electron transport chain
3: GO: Cellular Component:mitochondrial matrix
4: Human Phenotype:Increased serum lactate
5: Mouse Phenotype:abnormal mitochondrial physiology
7: Pathway:The citric acid (TCA) cycle and respiratory electron transport
9: Interaction:MRPL58 interactions
10: Cytoband: 11q13
11: Transcription Factor Binding Site:V$ELK1 02
12: Gene Family:Mitochondrial ribosomal proteins
13: Coexpression:Genes up-regulated in non-spontaneously immortalizing (NSI) primary breast cancer tumor cultures upon expression of TERT [GeneID=7015] off a retroviral vector.
14: Coexpression Atlas:54SK Top 500 All
|
*
* |
IC4- (1 genes) |
none |
| IC5+ (294 genes) |
1: GO: Molecular Function:ubiquitin-like protein ligase activity
2: GO: Biological Process:regulation of protein modification by small protein conjugation or removal
5: Mouse Phenotype:abnormal forebrain development
9: Interaction:UNK interactions
11: Transcription Factor Binding Site:TTAYRTAA V$E4BP4 01
12: Gene Family:RNA binding motif containing
13: Coexpression:Genes down-regulated upon overexpression of PARVB [GeneID=29780] in MDA-MB-231 cells (breast cancer) cultured in 3D collagen I and 3D Matrigel only.
14: Coexpression Atlas:fetal replicating Top 500 Cluster 3
16: MicroRNA: hsa-miR-32:PITA TOP
18: Disease:Multiple malignancy
|
*
* |
IC5- (38 genes) |
14: Coexpression Atlas:Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5
|
| IC6+ (428 genes) |
1: GO: Molecular Function:NADH dehydrogenase (ubiquinone) activity
2: GO: Biological Process:cellular respiration
3: GO: Cellular Component:mitochondrial protein complex
4: Human Phenotype:Lactic acidosis
5: Mouse Phenotype:embryonic lethality before implantation
6: Domain:Proteasome sua/b
7: Pathway:The citric acid (TCA) cycle and respiratory electron transport
9: Interaction:VCAM1 interactions
11: Transcription Factor Binding Site:V$ELK1 02
12: Gene Family:Proteasome
13: Coexpression:Genes encoding proteins involved in oxidative phosphorylation.
14: Coexpression Atlas:Mouse Lung E14.5 Epithelial top 500
|
*
* |
IC6- (1 genes) |
none |
| IC7+ (173 genes) |
1: GO: Molecular Function:aminoacyl-tRNA ligase activity
2: GO: Biological Process:cellular amino acid metabolic process
7: Pathway:Cytosolic tRNA aminoacylation
9: Interaction:AARS interactions
13: Coexpression:Selected genes up-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [GeneID=3265].
14: Coexpression Atlas:SC-LF blastocyst vs SC blastocyst-Confounder removed-fold2.0 adjp0.05
18: Disease:Endothelial dysfunction
|
*
* |
IC7- (65 genes) |
2: GO: Biological Process:multi-multicellular organism process
7: Pathway:Direct p53 effectors
13: Coexpression:Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] MCF-7 cells (breast cancer) stably over-expressing constitutively active RAF1 [Gene ID=5894] gene.
|
| IC8+ (290 genes) |
1: GO: Molecular Function:actin binding
2: GO: Biological Process:muscle tissue development
3: GO: Cellular Component:contractile fiber part
4: Human Phenotype:Dilated cardiomyopathy
5: Mouse Phenotype:abnormal muscle fiber morphology
6: Domain:Ig I-set
7: Pathway:Striated Muscle Contraction
9: Interaction:TNNI1 interactions
11: Transcription Factor Binding Site:CTAWWWATA V$RSRFC4 Q2
12: Gene Family:CD molecules|V-set domain containing|I-set domain containing|Sialic acid binding Ig like lectins
13: Coexpression:Genes involved in development of skeletal muscle (myogenesis).
14: Coexpression Atlas:80Dn Top 500 All
16: MicroRNA: hsa-miR-320c:PITA TOP
18: Disease:Congenital myopathy (disorder)
|
*
* |
IC8- (69 genes) |
1: GO: Molecular Function:glycosaminoglycan binding
2: GO: Biological Process:extracellular matrix organization
3: GO: Cellular Component:extracellular matrix
5: Mouse Phenotype:abnormal trabecular bone morphology
7: Pathway:Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
13: Coexpression:Genes defining epithelial-mesenchymal transition, as in wound healing, fibrosis and metastasis.
14: Coexpression Atlas:Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4
|
| IC9+ (275 genes) |
1: GO: Molecular Function:helicase activity
2: GO: Biological Process:mRNA processing
3: GO: Cellular Component:nuclear body
5: Mouse Phenotype:embryonic lethality between implantation and placentation
6: Domain:HELICc
7: Pathway:mRNA processing
9: Interaction:RPA2 interactions
11: Transcription Factor Binding Site:V$NFMUE1 Q6
12: Gene Family:RNA binding motif containing
13: Coexpression:Common down-regulated transcripts in fibroblasts expressing either XP/CS or TDD mutant forms of ERCC3 [GeneID=2071], after UVC irradiation.
14: Coexpression Atlas:FacebaseRNAseq e10.5 Neural Epithelium Flanking Eminence top-relative-expression-ranked 1000 k-means-cluster#2
16: MicroRNA: hsa-miR-548m:PITA TOP
18: Disease:Intellectual Disability
|
*
* |
IC9- (7 genes) |
none |
| IC10+ (220 genes) |
1: GO: Molecular Function:transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
2: GO: Biological Process:ossification
3: GO: Cellular Component:perikaryon
5: Mouse Phenotype:abnormal bone ossification
6: Domain:Homeodomain-like
7: Pathway:Pathways in cancer
11: Transcription Factor Binding Site:V$PBX1 01
13: Coexpression:Genes up-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein.
14: Coexpression Atlas:54Dn SubClass 54Dn 1SK Top 500 All
16: MicroRNA: hsa-miR-624:PITA TOP
18: Disease:Ewings sarcoma
|
*
* |
IC10- (54 genes) |
2: GO: Biological Process:extracellular matrix organization
3: GO: Cellular Component:extracellular matrix
5: Mouse Phenotype:abnormal muscle contractility
7: Pathway:Extracellular matrix organization
13: Coexpression:Genes up-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi.
14: Coexpression Atlas:Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3
|
| IC11+ (50 genes) |
2: GO: Biological Process:microtubule-based movement
13: Coexpression:Genes down-regulated in nsopharyngeal carcinoma relative to the normal tissue.
|
*
* |
IC11- (16 genes) |
none |
| IC12+ (266 genes) |
2: GO: Biological Process:type I interferon signaling pathway
5: Mouse Phenotype:increased susceptibility to viral infection
7: Pathway:Interferon alpha/beta signaling
11: Transcription Factor Binding Site:V$OCT Q6
13: Coexpression:Genes up-regulated in cells from peripheral lymph nodes: T reg versus T conv.
14: Coexpression Atlas:kidney adult RenMedVasc Tie2 top-relative-expression-ranked 500
16: MicroRNA: hsa-miR-641:PITA TOP
18: Disease:Influenza
|
*
* |
IC12- (68 genes) |
3: GO: Cellular Component:adherens junction
13: Coexpression:Genes up-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein.
14: Coexpression Atlas:Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3
|
| IC13+ (168 genes) |
1: GO: Molecular Function:transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
2: GO: Biological Process:negative regulation of protein phosphorylation
5: Mouse Phenotype:abnormal fat pad morphology
6: Domain:BRLZ
7: Pathway:ATF-2 transcription factor network
9: Interaction:DNMT3L interactions
11: Transcription Factor Binding Site:V$CREBP1 Q2
12: Gene Family:Basic leucine zipper proteins
13: Coexpression:Genes regulated by NF-kB in response to TNF [GeneID=7124].
14: Coexpression Atlas:endothelial Top 500 All
16: MicroRNA:miR-181c:PicTar
18: Disease:Myocardial Ischemia
|
*
* |
IC13- (54 genes) |
13: Coexpression:Genes down-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones.
14: Coexpression Atlas:kidney adult RenalCapsule top-relative-expression-ranked 500
|
| IC14+ (158 genes) |
1: GO: Molecular Function:monosaccharide binding
2: GO: Biological Process:glucose catabolic process
3: GO: Cellular Component:myelin sheath
5: Mouse Phenotype:abnormal liver weight
7: Pathway:Glycolysis and Gluconeogenesis
9: Interaction:ENO1 interactions
11: Transcription Factor Binding Site:V$HIF1 Q3
13: Coexpression:Genes up-regulated in MCF7 cells (breast cancer) treated with hypoxia mimetic DMOG [PubChem=3080614].
14: Coexpression Atlas:26Dn SubClass 26Dn 2 Top 500 All
18: Disease:Anaplastic astrocytoma
|
*
* |
IC14- (50 genes) |
14: Coexpression Atlas:54Dn Top 500 All
|
| IC15+ (200 genes) |
1: GO: Molecular Function:growth factor binding
2: GO: Biological Process:angiogenesis
12: Gene Family:CD molecules|V-set domain containing|Immunoglobulin like domain containing|Carcinoembryonic antigen related cell adhesion molecule family
13: Coexpression:Genes down-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi.
14: Coexpression Atlas:Stromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4
16: MicroRNA:hsa-miR-338-3p:TargetScan
18: Disease:Idiopathic Pulmonary Fibrosis
|
*
* |
IC15- (132 genes) |
1: GO: Molecular Function:cell adhesion molecule binding
2: GO: Biological Process:angiogenesis
3: GO: Cellular Component:extracellular matrix
5: Mouse Phenotype:aorticopulmonary septal defect
7: Pathway:Focal adhesion
11: Transcription Factor Binding Site:V$SOX9 B1
13: Coexpression:Genes up-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi.
14: Coexpression Atlas:Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3
16: MicroRNA: hsa-miR-890:PITA TOP
18: Disease:Pulmonary Fibrosis
|
| IC16+ (169 genes) |
1: GO: Molecular Function:actin binding
2: GO: Biological Process:muscle filament sliding
3: GO: Cellular Component:contractile fiber
5: Mouse Phenotype:abnormal muscle fiber morphology
7: Pathway:Striated Muscle Contraction
9: Interaction:TRIM63 interactions
11: Transcription Factor Binding Site:V$MEF2 02
13: Coexpression:Genes involved in development of skeletal muscle (myogenesis).
14: Coexpression Atlas:DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 top-relative-expression-ranked 500
18: Disease:Congenital myopathy (disorder)
|
*
* |
IC16- (75 genes) |
13: Coexpression:Genes up-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi.
14: Coexpression Atlas:kidney adult RenalCapsule top-relative-expression-ranked 500
16: MicroRNA: hsa-miR-211:PITA TOP
18: Disease:Hyperglycemia
|
| IC17+ (178 genes) |
2: GO: Biological Process:ribonucleoprotein complex biogenesis
3: GO: Cellular Component:mitochondrial matrix
13: Coexpression:Genes down-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [GeneID=921] off a plasmid vector.
14: Coexpression Atlas:e8.5 NeuroEpith nonFloorPlate top-relative-expression-ranked 500 2
|
*
* |
IC17- (4 genes) |
none |
| IC18+ (204 genes) |
1: GO: Molecular Function:glycosaminoglycan binding
2: GO: Biological Process:extracellular matrix organization
3: GO: Cellular Component:extracellular matrix
5: Mouse Phenotype:abnormal trabecular bone morphology
6: Domain:Collagen
7: Pathway:Extracellular matrix organization
9: Interaction:COL1A1 interactions
12: Gene Family:CD molecules|V-set domain containing|Immunoglobulin like domain containing|Carcinoembryonic antigen related cell adhesion molecule family
13: Coexpression:Genes up-regulated in invasive ductal carcinoma (IDC) relative to ductal carcinoma in situ (DCIS, non-invasive).
14: Coexpression Atlas:Progenitor-Cell-Biology-Consortium reference CardiacMyocyte top-relative-expression-ranked 500
16: MicroRNA:CAGTATT,MIR-200B:MSigDB
18: Disease:Pulmonary Fibrosis
|
*
* |
IC18- (84 genes) |
5: Mouse Phenotype:abnormal cardiac muscle contractility
13: Coexpression:Genes up-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein.
14: Coexpression Atlas:dev gonad e13.5 F VascAssocMesenchStromOvary Sma top-relative-expression-ranked 500
18: Disease:Rhabdomyosarcoma
|
| IC19+ (151 genes) |
13: Coexpression:Genes down-regulated in glomeruli of kidneys from patients with diabetic nephropathy (type 2 diabetes mellitus).
14: Coexpression Atlas:54Dn SubClass 54Dn 1SK Top 500 All
16: MicroRNA: hsa-miR-421:PITA TOP
|
*
* |
IC19- (19 genes) |
none |
| IC20+ (136 genes) |
1: GO: Molecular Function:glycosaminoglycan binding
2: GO: Biological Process:regulation of angiogenesis
3: GO: Cellular Component:axon part
13: Coexpression:Up-regulated genes detecting gender effects in global expression profiling studies.
14: Coexpression Atlas:Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4
16: MicroRNA:miR-203:PicTar
18: Disease:Plaque, Amyloid
|
*
* |
IC20- (155 genes) |
1: GO: Molecular Function:extracellular matrix structural constituent
2: GO: Biological Process:extracellular matrix organization
3: GO: Cellular Component:extracellular matrix
5: Mouse Phenotype:small kidney
7: Pathway:Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
11: Transcription Factor Binding Site:GCTNWTTGK UNKNOWN
13: Coexpression:Genes down-regulated in TC71 and EWS502 cells (Ewing's sarcoma) by EWSR1-FLI1 [GeneID=2130;2314] as inferred from RNAi knockdown of this fusion protein.
14: Coexpression Atlas:Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3
16: MicroRNA: hsa-miR-539:PITA TOP
18: Disease:Neoplasm Invasiveness
|
| IC21+ (212 genes) |
2: GO: Biological Process:axon ensheathment
3: GO: Cellular Component:myelin sheath
5: Mouse Phenotype:abnormal myelin sheath morphology
7: Pathway:Lysosome
9: Interaction:CLN8 interactions
13: Coexpression:Genes down-regulated in the temporal cortex samples from patients with major depressive disorder.
14: Coexpression Atlas:oligodendrocytes Top 500 All
18: Disease:Lysosomal Storage Diseases
|
*
* |
IC21- (46 genes) |
2: GO: Biological Process:ribosome biogenesis
9: Interaction:FBL interactions
13: Coexpression:Genes down-regulated in BJAB cells (B-lymphoma) after glutamine [PubChem=738] deprivation.
14: Coexpression Atlas:dev gonad e11.5 M PrimGermCell Oct k-means-cluster#4 top-relative-expression-ranked 1000
|
| IC22+ (232 genes) |
2: GO: Biological Process:interferon-gamma-mediated signaling pathway
5: Mouse Phenotype:abnormal blood vessel physiology
6: Domain:EGF CA
7: Pathway:Staphylococcus aureus infection
10: Cytoband: 6p21.3
13: Coexpression:Up-regulated genes in angioimmunoblastic lymphoma (AILT) compared to normal T lymphocytes.
14: Coexpression Atlas:astrocytes Top 500 All
18: Disease:Pulmonary Fibrosis
|
*
* |
IC22- (45 genes) |
14: Coexpression Atlas:OPC Top 500 All
|
| IC23+ (242 genes) |
1: GO: Molecular Function:tubulin binding
2: GO: Biological Process:axonogenesis
3: GO: Cellular Component:postsynapse
5: Mouse Phenotype:abnormal neuron differentiation
9: Interaction:DGUOK interactions
11: Transcription Factor Binding Site:YAATNRNNNYNATT UNKNOWN
13: Coexpression:Neuroblastoma markers down-regulated in neuroblastoma cell lines expressing ESWR1-FLI1 [GeneID=2130;2313] fusion protein.
14: Coexpression Atlas:dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 top-relative-expression-ranked 500
16: MicroRNA: hsa-miR-129-5p:PITA TOP
18: Disease:Extrapyramidal sign
|
*
* |
IC23- (45 genes) |
13: Coexpression:Up-regulated genes in MM1.S cells (multiple myeloma) treated with adaphostin [PubChem=387042], a tyrosine kinase inhibitor with anticancer properties.
14: Coexpression Atlas:endothelial Top 500 All
|
| IC24+ (209 genes) |
1: GO: Molecular Function:glycosaminoglycan binding
2: GO: Biological Process:modulation of synaptic transmission
3: GO: Cellular Component:dendritic spine
7: Pathway:Cell adhesion molecules (CAMs)
11: Transcription Factor Binding Site:V$TST1 01
12: Gene Family:Fibronectin type III domain containing|Immunoglobulin like domain containing
13: Coexpression:Genes up-regulated in epithelial kidney cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene.
14: Coexpression Atlas:OPC Top 500 All
16: MicroRNA: hsa-miR-216b:PITA TOP
|
*
* |
IC24- (65 genes) |
2: GO: Biological Process:angiogenesis
3: GO: Cellular Component:focal adhesion
9: Interaction:VCAM1 interactions
13: Coexpression:Housekeeping genes identified as expressed across 19 normal tissues.
14: Coexpression Atlas:endothelial Top 500 All
18: Disease:Non-Neoplastic Disorder
|
| IC25+ (130 genes) |
2: GO: Biological Process:sterol biosynthetic process
5: Mouse Phenotype:abnormal hepatobiliary system physiology
7: Pathway:Steroid Biosynthesis
9: Interaction:TCTN3 interactions
13: Coexpression:Genes up-regulated through activation of mTORC1 complex.
14: Coexpression Atlas:dev gonad e13.5 M DevVasTestis Flk k-means-cluster#1 top-relative-expression-ranked 500
16: MicroRNA:miR-101:PicTar
|
*
* |
IC25- (69 genes) |
2: GO: Biological Process:ossification
13: Coexpression:Genes up-regulated in cultured stromal stem cells from adipose tissue, compared to the freshly isolated cells.
14: Coexpression Atlas:Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4
18: Disease:Idiopathic Pulmonary Fibrosis
|
| IC26+ (202 genes) |
1: GO: Molecular Function:glycosaminoglycan binding
2: GO: Biological Process:extracellular matrix organization
3: GO: Cellular Component:extracellular matrix
4: Human Phenotype:Joint laxity
5: Mouse Phenotype:abnormal cartilage morphology
6: Domain:EGF 2
7: Pathway:Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
9: Interaction:PDGFA interactions
11: Transcription Factor Binding Site:GTGGGTGK UNKNOWN
13: Coexpression:Genes up-regulated in invasive ductal carcinoma (IDC) relative to ductal carcinoma in situ (DCIS, non-invasive).
14: Coexpression Atlas:Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3
18: Disease:Tumor Angiogenesis
|
*
* |
IC26- (83 genes) |
2: GO: Biological Process:response to oxygen levels
5: Mouse Phenotype:abnormal cardiac muscle contractility
13: Coexpression:Genes down-regulated in MCF7 cells (breast cancer) after knockdown of both HIF1A and HIF2A [GeneID=3091;2034] by RNAi.
16: MicroRNA:hsa-miR-323b-5p:mirSVR nonconserved highEffect-0.5
18: Disease:Lip and Oral Cavity Carcinoma
|
| IC27+ (260 genes) |
1: GO: Molecular Function:active transmembrane transporter activity
2: GO: Biological Process:modulation of synaptic transmission
3: GO: Cellular Component:extracellular matrix component
5: Mouse Phenotype:abnormal wound healing
6: Domain:fn3
7: Pathway:Extracellular matrix organization
11: Transcription Factor Binding Site:V$E47 02
12: Gene Family:Fibronectin type III domain containing|Immunoglobulin like domain containing
13: Coexpression:Genes correlated with classical type of glioblastoma multiforme tumors.
14: Coexpression Atlas:astrocytes Top 500 All
16: MicroRNA: hsa-miR-448:PITA TOP
18: Disease:Anaplastic astrocytoma
|
*
* |
IC27- (42 genes) |
16: MicroRNA: hsa-miR-1264:PITA TOP
|
| IC28+ (141 genes) |
3: GO: Cellular Component:apical plasma membrane
13: Coexpression:Genes down-regulated in ES (embryonic stem cells) with defficient SUZ12 [GeneID=23512].
14: Coexpression Atlas:80Dn Top 500 All
16: MicroRNA:GTACTGT,MIR-101:MSigDB
18: Disease:Non-Neoplastic Disorder
|
*
* |
IC28- (97 genes) |
13: Coexpression:Genes down-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [GeneID=6605] off a retroviral vector.
14: Coexpression Atlas:kidney adult RenalCapsule k-means-cluster#4 top-relative-expression-ranked 500
|
| IC29+ (107 genes) |
11: Transcription Factor Binding Site:V$SOX5 01
13: Coexpression:Down-regulated genes in the canonical gene expression signature of the fibroblast core serum response (CSR) defined by the Stanford group.
14: Coexpression Atlas:80Dn Top 500 All
16: MicroRNA:hsa-miR-1225-5p:mirSVR nonconserved highEffect-0.5
|
*
* |
IC29- (102 genes) |
2: GO: Biological Process:regulation of wound healing
3: GO: Cellular Component:endoplasmic reticulum lumen
9: Interaction:TCTN1 interactions
13: Coexpression:Genes regulated by hypoxia, based on literature searches.
14: Coexpression Atlas:Myeloid Cells, DC.LC.Sk, MHCII+ CD11b+ CD45+, Skin, avg-2
16: MicroRNA:miR-199a-star:PicTar
18: Disease:Cerebral Ischemia
|
| IC30+ (252 genes) |
1: GO: Molecular Function:extracellular matrix structural constituent
2: GO: Biological Process:extracellular matrix organization
3: GO: Cellular Component:extracellular matrix
5: Mouse Phenotype:pathological neovascularization
6: Domain:EGF-like CS
7: Pathway:Extracellular matrix organization
9: Interaction:MYH9 interactions
13: Coexpression:Genes defining epithelial-mesenchymal transition, as in wound healing, fibrosis and metastasis.
14: Coexpression Atlas:Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3
16: MicroRNA: hsa-miR-145:PITA TOP
18: Disease:Vascular Diseases
|
*
* |
IC30- (90 genes) |
2: GO: Biological Process:skeletal muscle organ development
3: GO: Cellular Component:proteinaceous extracellular matrix
5: Mouse Phenotype:abnormal forelimb morphology
13: Coexpression:Genes up-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi.
14: Coexpression Atlas:Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4
|