Toppgene analysis for aggregated_1964_log, IC20, positive side

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1: GO: Molecular Function [Display Chart] 446 annotations before applied cutoff / 18819 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0005539 glycosaminoglycan binding 2.051E-6 9.148E-4 6.109E-3 9.148E-4 10 219
2 GO:0031716 calcitonin receptor binding 1.307E-4 2.915E-2
1.947E-1
5.831E-2
 2 3

2: GO: Biological Process [Display Chart] 2953 annotations before applied cutoff / 18785 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0045765 regulation of angiogenesis 7.993E-7 2.360E-3 2.022E-2 2.360E-3 11 239
2 GO:1901342 regulation of vasculature development 2.113E-6 3.120E-3 2.673E-2 6.240E-3 11 264
3 GO:0050727 regulation of inflammatory response 2.640E-5 1.759E-2
1.507E-1
7.796E-2
 11 345
4 GO:0050679 positive regulation of epithelial cell proliferation 3.067E-5 1.759E-2
1.507E-1
9.057E-2
 8 177
5 GO:0010631 epithelial cell migration 3.590E-5 1.759E-2
1.507E-1
1.060E-1
 9 235
6 GO:0090132 epithelium migration 3.964E-5 1.759E-2
1.507E-1
1.170E-1
 9 238
7 GO:0001984 vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure 4.680E-5 1.759E-2
1.507E-1
1.382E-1
 2 2
8 GO:0090130 tissue migration 4.810E-5 1.759E-2
1.507E-1
1.420E-1
 9 244
9 GO:0030335 positive regulation of cell migration 5.898E-5 1.759E-2
1.507E-1
1.742E-1
 12 446
10 GO:2000147 positive regulation of cell motility 7.756E-5 1.759E-2
1.507E-1
2.290E-1
 12 459
11 GO:0000956 nuclear-transcribed mRNA catabolic process 7.806E-5 1.759E-2
1.507E-1
2.305E-1
 8 202
12 GO:0045651 positive regulation of macrophage differentiation 8.605E-5 1.759E-2
1.507E-1
2.541E-1
 3 13
13 GO:0050673 epithelial cell proliferation 8.747E-5 1.759E-2
1.507E-1
2.583E-1
 11 394
14 GO:0002576 platelet degranulation 9.567E-5 1.759E-2
1.507E-1
2.825E-1
 6 107
15 GO:0051272 positive regulation of cellular component movement 9.899E-5 1.759E-2
1.507E-1
2.923E-1
 12 471
16 GO:1903034 regulation of response to wounding 1.093E-4 1.759E-2
1.507E-1
3.228E-1
 12 476
17 GO:0007611 learning or memory 1.106E-4 1.759E-2
1.507E-1
3.265E-1
 9 272
18 GO:0040017 positive regulation of locomotion 1.137E-4 1.759E-2
1.507E-1
3.358E-1
 12 478
19 GO:0006402 mRNA catabolic process 1.325E-4 1.759E-2
1.507E-1
3.912E-1
 8 218
20 GO:0050961 detection of temperature stimulus involved in sensory perception 1.355E-4 1.759E-2
1.507E-1
4.002E-1
 3 15
21 GO:0050965 detection of temperature stimulus involved in sensory perception of pain 1.355E-4 1.759E-2
1.507E-1
4.002E-1
 3 15
22 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1.398E-4 1.759E-2
1.507E-1
4.127E-1
 2 3
23 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway 1.398E-4 1.759E-2
1.507E-1
4.127E-1
 2 3
24 GO:0001667 ameboidal-type cell migration 1.429E-4 1.759E-2
1.507E-1
4.221E-1
 10 347
25 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 1.882E-4 2.223E-2
1.904E-1
5.557E-1
 6 121
26 GO:0010632 regulation of epithelial cell migration 2.079E-4 2.351E-2
2.015E-1
6.139E-1
 7 175
27 GO:0050728 negative regulation of inflammatory response 2.150E-4 2.351E-2
2.015E-1
6.349E-1
 6 124
28 GO:0050890 cognition 2.540E-4 2.679E-2
2.295E-1
7.500E-1
 9 304
29 GO:0003166 bundle of His development 2.782E-4 2.739E-2
2.347E-1
8.217E-1
 2 4
30 GO:0001983 baroreceptor response to increased systemic arterial blood pressure 2.782E-4 2.739E-2
2.347E-1
8.217E-1
 2 4
31 GO:0016525 negative regulation of angiogenesis 2.986E-4 2.845E-2
2.437E-1
8.819E-1
 5 85
32 GO:0006401 RNA catabolic process 3.097E-4 2.858E-2
2.449E-1
9.146E-1
 8 247
33 GO:0016048 detection of temperature stimulus 3.311E-4 2.871E-2
2.460E-1
9.778E-1
 3 20
34 GO:0036499 PERK-mediated unfolded protein response 3.311E-4 2.871E-2
2.460E-1
9.778E-1
 3 20
35 GO:2000181 negative regulation of blood vessel morphogenesis 3.509E-4 2.871E-2
2.460E-1
1.000E0
 5 88
36 GO:0001525 angiogenesis 3.670E-4 2.871E-2
2.460E-1
1.000E0
 11 465
37 GO:0032102 negative regulation of response to external stimulus 3.699E-4 2.871E-2
2.460E-1
1.000E0
 9 320
38 GO:0034138 toll-like receptor 3 signaling pathway 3.844E-4 2.871E-2
2.460E-1
1.000E0
 3 21
39 GO:0045649 regulation of macrophage differentiation 3.844E-4 2.871E-2
2.460E-1
1.000E0
 3 21
40 GO:0006413 translational initiation 3.889E-4 2.871E-2
2.460E-1
1.000E0
 7 194
41 GO:0050678 regulation of epithelial cell proliferation 4.233E-4 2.964E-2
2.539E-1
1.000E0
 9 326
42 GO:0050951 sensory perception of temperature stimulus 4.428E-4 2.964E-2
2.539E-1
1.000E0
 3 22
43 GO:0033555 multicellular organismal response to stress 4.529E-4 2.964E-2
2.539E-1
1.000E0
 5 93
44 GO:0071279 cellular response to cobalt ion 4.617E-4 2.964E-2
2.539E-1
1.000E0
 2 5
45 GO:0003164 His-Purkinje system development 4.617E-4 2.964E-2
2.539E-1
1.000E0
 2 5
46 GO:0010637 negative regulation of mitochondrial fusion 4.617E-4 2.964E-2
2.539E-1
1.000E0
 2 5
47 GO:1901343 negative regulation of vasculature development 4.758E-4 2.989E-2
2.561E-1
1.000E0
 5 94
48 GO:0017148 negative regulation of translation 4.979E-4 3.063E-2
2.624E-1
1.000E0
 6 145
49 GO:0031663 lipopolysaccharide-mediated signaling pathway 5.914E-4 3.564E-2
3.054E-1
1.000E0
 4 56
50 GO:0007584 response to nutrient 6.067E-4 3.583E-2
3.070E-1
1.000E0
 7 209
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 290 annotations before applied cutoff / 19172 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0033267 axon part 1.112E-6 3.225E-4 2.015E-3 3.225E-4 12 309
2 GO:0043679 axon terminus 3.581E-5 4.189E-3 2.617E-2 1.038E-2 8 186
3 GO:0043204 perikaryon 5.164E-5 4.189E-3 2.617E-2 1.498E-2 7 144
4 GO:0044306 neuron projection terminus 5.777E-5 4.189E-3 2.617E-2 1.675E-2 8 199
5 GO:0031983 vesicle lumen 8.637E-5 4.846E-3 3.028E-2 2.505E-2 6 108
6 GO:0031089 platelet dense granule lumen 1.003E-4 4.846E-3 3.028E-2 2.908E-2 3 14
7 GO:0031012 extracellular matrix 1.945E-4 8.057E-3
5.035E-2
5.640E-2
 11 444
8 GO:0005578 proteinaceous extracellular matrix 2.321E-4 8.414E-3
5.257E-2
6.731E-2
 10 379
9 GO:0034774 secretory granule lumen 2.624E-4 8.457E-3
5.284E-2
7.611E-2
 5 85
10 GO:0042827 platelet dense granule 3.050E-4 8.844E-3
5.526E-2
8.844E-2
 3 20
11 GO:0030141 secretory granule 3.632E-4 9.575E-3
5.983E-2
1.053E-1
 10 401
12 GO:0044420 extracellular matrix component 3.987E-4 9.635E-3
6.021E-2
1.156E-1
 6 143
13 GO:0060205 cytoplasmic vesicle lumen 6.652E-4 1.484E-2
9.273E-2
1.929E-1
 5 104
14 GO:0043195 terminal bouton 9.302E-4 1.927E-2
1.204E-1
2.698E-1
 5 112
15 GO:0043203 axon hillock 1.206E-3 2.332E-2
1.457E-1
3.498E-1
 2 8
16 GO:0060076 excitatory synapse 1.750E-3 3.172E-2
1.982E-1
5.075E-1
 7 258
17 GO:0098793 presynapse 2.079E-3 3.546E-2
2.216E-1
6.028E-1
 8 341
18 GO:0005581 collagen trimer 2.868E-3 4.621E-2
2.888E-1
8.318E-1
 4 88
Show 13 more annotations

4: Human Phenotype [Display Chart] 418 annotations before applied cutoff / 4410 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0001450 Y-linked inheritance 3.409E-5 1.425E-2
9.424E-2
 1.425E-2 4 22

5: Mouse Phenotype [Display Chart] 2291 annotations before applied cutoff / 9299 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0002267 abnormal bronchiole morphology 9.891E-6 1.311E-2
1.090E-1
 2.266E-2 6 52
2 MP:0010897 abnormal bronchiole epithelium morphology 1.455E-5 1.311E-2
1.090E-1
 3.334E-2 5 33
3 MP:0020160 abnormal behavioral response to nicotine 1.717E-5 1.311E-2
1.090E-1
 3.934E-2 3 6
4 MP:0008415 abnormal neurite morphology 4.373E-5 2.505E-2
2.082E-1
1.002E-1
 14 418
5 MP:0003089 decreased skin tensile strength 8.885E-5 3.976E-2
3.306E-1
2.036E-1
 4 25
6 MP:0008143 abnormal dendrite morphology 1.150E-4 3.976E-2
3.306E-1
2.634E-1
 9 197
7 MP:0009745 abnormal behavioral response to xenobiotic 1.215E-4 3.976E-2
3.306E-1
2.783E-1
 11 295
8 MP:0005275 abnormal skin tensile strength 1.620E-4 4.638E-2
3.856E-1
3.711E-1
 4 29
Show 3 more annotations

6: Domain [Display Chart] 971 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR015476 Calcitonin gene-rel peptide InterPro 4.632E-5 2.239E-2
1.669E-1
 4.497E-2 2 2
2 IPR021117 Calcitonin-like InterPro 1.383E-4 2.239E-2
1.669E-1
1.343E-1
 2 3
3 IPR018360 Calcitonin CS InterPro 1.383E-4 2.239E-2
1.669E-1
1.343E-1
 2 3
4 IPR001693 Calcitonin peptide-like InterPro 1.383E-4 2.239E-2
1.669E-1
1.343E-1
 2 3
5 PS00258 CALCITONIN PROSITE 1.383E-4 2.239E-2
1.669E-1
1.343E-1
 2 3
6 SM00113 CALCITONIN SMART 1.383E-4 2.239E-2
1.669E-1
1.343E-1
 2 3
7 IPR003884 FacI MAC InterPro 2.754E-4 3.343E-2
2.492E-1
2.674E-1
 2 4
8 SM00057 FIMAC SMART 2.754E-4 3.343E-2
2.492E-1
2.674E-1
 2 4
9 IPR021116 Calcitonin/adrenomedullin InterPro 4.570E-4 4.437E-2
3.308E-1
4.437E-1
 2 5
10 PF00214 Calc CGRP IAPP Pfam 4.570E-4 4.437E-2
3.308E-1
4.437E-1
 2 5
Show 5 more annotations

7: Pathway [Display Chart] 775 annotations before applied cutoff / 10916 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 739007 Spinal Cord Injury BioSystems: WikiPathways 3.674E-5 2.847E-2
2.059E-1
 2.847E-2 7 112

8: Pubmed [Display Chart] 29746 annotations before applied cutoff / 51853 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 19086053 Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. Pubmed 5.227E-9 7.634E-5 8.303E-4 1.555E-4 10 300
2 19086053:gr Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. GeneRIF 5.227E-9 7.634E-5 8.303E-4 1.555E-4 10 300
3 12815422 The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. Pubmed 1.177E-8 7.634E-5 8.303E-4 3.502E-4 9 241
4 15336555 Pancreatic tumor cells influence the composition of the extracellular matrix. Pubmed 1.540E-8 7.634E-5 8.303E-4 4.580E-4 3 3
5 15336555:gr Pancreatic tumor cells influence the composition of the extracellular matrix. GeneRIF 1.540E-8 7.634E-5 8.303E-4 4.580E-4 3 3
6 10861003 Population genetic implications from sequence variation in four Y chromosome genes. Pubmed 1.540E-8 7.634E-5 8.303E-4 4.580E-4 3 3
7 14660691 Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches. Pubmed 2.650E-8 1.126E-4 1.225E-3 7.882E-4 4 13
8 19453261:gr High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. GeneRIF 5.218E-8 1.725E-4 1.876E-3 1.552E-3 10 383
9 19453261 High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Pubmed 5.218E-8 1.725E-4 1.876E-3 1.552E-3 10 383
10 10767340 Deletion and expression analysis of AZFa genes on the human Y chromosome revealed a major role for DBY in male infertility. Pubmed 1.534E-7 4.148E-4 4.513E-3 4.563E-3 3 5
11 23806407:gr Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model. GeneRIF 1.534E-7 4.148E-4 4.513E-3 4.563E-3 3 5
12 20628624:gr Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". GeneRIF 2.930E-7 6.704E-4 7.293E-3 8.716E-3 7 172
13 20628624 Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". Pubmed 2.930E-7 6.704E-4 7.293E-3 8.716E-3 7 172
14 9381176 Functional coherence of the human Y chromosome. Pubmed 4.580E-7 9.731E-4 1.059E-2 1.362E-2 4 25
15 15599946 The expression and regulation of ADAMTS-1, -4, -5, -9, and -15, and TIMP-3 by TGFbeta1 in prostate cells: relevance to the accumulation of versican. Pubmed 5.350E-7 9.946E-4 1.082E-2 1.591E-2 3 7
16 15599946:gr The expression and regulation of ADAMTS-1, -4, -5, -9, and -15, and TIMP-3 by TGFbeta1 in prostate cells: relevance to the accumulation of versican. GeneRIF 5.350E-7 9.946E-4 1.082E-2 1.591E-2 3 7
17 23597562 Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. Pubmed 4.315E-6 1.374E-3 1.495E-2
1.283E-1
 4 43
18 20050020 Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin. Pubmed 4.323E-6 1.374E-3 1.495E-2
1.286E-1
 3 13
19 20050020:gr Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin. GeneRIF 4.323E-6 1.374E-3 1.495E-2
1.286E-1
 3 13
20 20551380 Proteomics characterization of extracellular space components in the human aorta. Pubmed 5.987E-6 1.374E-3 1.495E-2
1.781E-1
 5 101
21 15468368:gr Osteoarthritic mice exhibit enhanced prostaglandin E2 and unchanged calcitonin gene-related peptide release in a novel isolated knee joint model. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
22 20101710:gr Proteolytic cleavage of versican during limb joint development. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
23 23722394:gr Evaluation of pigment epithelium-derived factor and complement factor I polymorphisms as a cause of choroidal neovascularization in highly myopic eyes. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
24 23350658 Association of PTPN22 rs2476601 and EGFR rs17337023 Gene polymorphisms and rheumatoid arthritis in Zahedan, Southeast Iran. Pubmed 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
25 22383695:gr Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
26 18247373 The tetraspanin CD9 modulates epidermal growth factor receptor signaling in cancer cells. Pubmed 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
27 3492492 Identification in the human central nervous system, pituitary, and thyroid of a novel calcitonin gene-related peptide, and partial amino acid sequence in the spinal cord. Pubmed 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
28 26008593 Clinical utility of a novel urine-based gene fusion TTTY15-USP9Y in predicting prostate biopsy outcome. Pubmed 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
29 15039145:gr Ablation of calcitonin/calcitonin gene-related peptide-alpha impairs fetal magnesium but not calcium homeostasis. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
30 18307972:gr The role of calcitonin and alpha-calcitonin gene-related peptide in bone formation. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
31 23845159 Versican is upregulated in circulating monocytes in patients with systemic sclerosis and amplifies a CCL2-mediated pathogenic loop. Pubmed 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
32 21791066 Versican but not decorin accumulation is related to malignancy in mammographically detected high density and malignant-appearing microcalcifications in non-palpable breast carcinomas. Pubmed 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
33 14960307:gr The mouse FKBP23 binds to BiP in ER and the binding of C-terminal domain is interrelated with Ca2+ concentration. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
34 16118273:gr Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
35 15016615:gr In vitro activation of murine DRG neurons by CGRP-mediated mucosal mast cell degranulation. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
36 17335953:gr Endocytosis of the dermatan sulfate proteoglycan decorin utilizes multiple pathways and is modulated by epidermal growth factor receptor signaling. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
37 17986107:gr Calcitonin gene-related peptide mediates acid-induced lung injury in mice. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
38 18005945:gr Nonprincipal neurons and CA2 pyramidal cells, but not mossy cells are immunoreactive for calcitonin gene-related peptide in the mouse hippocampus. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
39 16143644:gr Role of calcitonin gene-related peptide in the postischemic anti-inflammatory effects of antecedent ethanol ingestion. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
40 19036156 Genetic variation in stromal proteins decorin and lumican with breast cancer: investigations in two case-control studies. Pubmed 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
41 17223077:gr The binding of FKBP23 to BiP modulates BiP's ATPase activity with its PPIase activity. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
42 17087955:gr Contribution of sensory neurons to sex difference in the development of stress-induced gastric mucosal injury in mice. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
43 19046367:gr Calcitonin gene-related peptide (CGRP) triggers Ca2+ responses in cultured astrocytes and in Bergmann glial cells from cerebellar slices. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
44 25992628 Pigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells. Pubmed 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
45 22563493:gr CGRP¿-expressing sensory neurons respond to stimuli that evoke sensations of pain and itch. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
46 21243003:gr Procalcitonin as an early predictor of postoperative infectious complications in patients with acute traumatic spinal cord injury. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
47 20959432:gr BDNF and CGRP interaction: implications in migraine susceptibility. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
48 23722394 Evaluation of pigment epithelium-derived factor and complement factor I polymorphisms as a cause of choroidal neovascularization in highly myopic eyes. Pubmed 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
49 17307332:gr Protein kinase Calpha mediates feedback inhibition of EGF receptor transactivation induced by Gq-coupled receptor agonists. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
50 19860701:gr Role of calcitonin gene-related Peptide in gastric mucosal defence and healing. GeneRIF 6.237E-6 1.374E-3 1.495E-2
1.855E-1
 2 2
Show 45 more annotations

9: Interaction [Display Chart] 3183 annotations before applied cutoff / 16534 genes in category

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10: Cytoband [Display Chart] 118 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Yq11 Yq11 1.081E-5 1.276E-3 6.828E-3 1.276E-3 3 12
2 9p22.3 9p22.3 1.398E-3 3.992E-2
2.137E-1
1.650E-1
 2 15
3 Yp11.3 Yp11.3 1.594E-3 3.992E-2
2.137E-1
1.881E-1
 2 16
4 11p15.2 11p15.2 1.802E-3 3.992E-2
2.137E-1
2.126E-1
 2 17
5 17q21.2 17q21.2 2.797E-3 3.992E-2
2.137E-1
3.301E-1
 3 75
6 4q13.3-q21.3 4q13.3-q21.3 3.722E-3 3.992E-2
2.137E-1
4.392E-1
 1 1
7 9q13-q21.2 9q13-q21.2 3.722E-3 3.992E-2
2.137E-1
4.392E-1
 1 1
8 16q22-q23 16q22-q23 3.722E-3 3.992E-2
2.137E-1
4.392E-1
 1 1
9 12q21.3-q22 12q21.3-q22 3.722E-3 3.992E-2
2.137E-1
4.392E-1
 1 1
10 11p15.2-p15.1 11p15.2-p15.1 3.722E-3 3.992E-2
2.137E-1
4.392E-1
 1 1
11 17q22-q23.2 17q22-q23.2 3.722E-3 3.992E-2
2.137E-1
4.392E-1
 1 1
Show 6 more annotations

11: Transcription Factor Binding Site [Display Chart] 465 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 89 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 870 Minor histocompatibility antigens genenames.org 6.107E-6 5.436E-4 2.757E-3 5.436E-4 5 51
2 542 Endogenous ligands genenames.org 2.894E-5 1.288E-3 6.532E-3 2.576E-3 8 237
3 573 Small leucine rich repeat proteoglycans genenames.org 1.650E-3 4.895E-2
2.483E-1
1.469E-1
 2 12

13: Coexpression [Display Chart] 5997 annotations before applied cutoff / 21867 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M17072 Up-regulated genes detecting gender effects in global expression profiling studies. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.123E-17 6.736E-14 6.249E-13 6.736E-14 8 9
2 M15981 Genes up-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.048E-14 3.141E-11 2.914E-10 6.283E-11 22 430
3 M2816 Genes up-regulated in CD34+ hematopoietic progenitor cells after knockdown of RPS14 [Gene ID=6208] by RNAi. MSigDB C6: Oncogenic Signatures (v5.1) 9.020E-12 1.803E-8 1.673E-7 5.409E-8 14 192
4 M5930 Genes defining epithelial-mesenchymal transition, as in wound healing, fibrosis and metastasis. MSigDB H: Hallmark Gene Sets (v5.1) 1.566E-11 2.347E-8 2.178E-7 9.390E-8 14 200
5 M1834 Genes up-regulated in freshly isolated CD31- [GeneID=5175] (stromal stem cells from adipose tissue) versus the CD31+ (non-stem) counterparts. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.482E-11 5.375E-8 4.986E-7 2.688E-7 15 260
6 M17923 Genes up-regulated in cultured stromal stem cells from adipose tissue, compared to the freshly isolated cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 7.632E-11 6.884E-8 6.386E-7 4.577E-7 18 425
7 M19432 Genes up-regulated during pubertal mammary gland development between week 4 and 5. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.035E-11 6.884E-8 6.386E-7 4.819E-7 15 271
8 M5126 Down-regulated genes in head and neck cancer compared to cervical carcinoma samples. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.121E-10 2.340E-7 2.171E-6 1.872E-6 7 29
9 M13256 Genes down-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.542E-9 1.027E-6 9.528E-6 9.244E-6 12 190
10 M7883 Genes most strongly up-regulated in kidney glomeruli isolated from TCF21 [GeneID=6943] knockout mice. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.979E-9 1.187E-6 1.101E-5 1.187E-5 7 37
11 M12828 Genes up-regulated in reverted NIH3T3 cells (fibroblasts transformed by activated KRAS [GeneID=3845] which then reverted to normal cells upon stable over-expression of a dominant negative form of CDC25 [GeneID=5923]) vs normal fibroblasts. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.594E-9 1.414E-6 1.312E-5 1.556E-5 10 120
12 M17471 Genes up-regulated in invasive ductal carcinoma (IDC) relative to ductal carcinoma in situ (DCIS, non-invasive). MSigDB C2: CGP Curated Gene Sets (v5.1) 2.862E-9 1.431E-6 1.327E-5 1.717E-5 15 351
13 M2572 Genes in the 'mesenchymal transition signature' common to all invasive cancer types. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.203E-9 1.939E-6 1.798E-5 2.520E-5 8 64
14 M4995 Genes specifically up-regulated in Cluster IIb of urothelial cell carcinom (UCC) tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.180E-8 5.056E-6 4.690E-5 7.079E-5 15 390
15 M19541 Genes commonly down-regulated in human alveolar rhabdomyosarcoma (ARMS) and its mouse model overexpressing PAX3-FOXO1 [GeneID=5077;2308] fusion. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.149E-8 8.592E-6 7.971E-5 1.289E-4 15 408
16 M5891 Genes up-regulated in response to low oxygen levels (hypoxia). MSigDB H: Hallmark Gene Sets (v5.1) 3.203E-8 1.201E-5 1.114E-4 1.921E-4 11 200
17 M13867 Genes up-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.351E-8 1.535E-5 1.424E-4 2.609E-4 12 256
18 M11654 Genes up-regulated in metaplastic carcinoma of the breast (MCB) subclass 2 compared to the MCB subclass 1. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.539E-8 1.845E-5 1.712E-4 3.322E-4 6 35
19 M12890 Genes up-regulated in HT1080 cells (fibrosarcoma) over-expressing MMP14 [GeneID=4323] compared to those with knockdown of the gene by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.620E-8 2.090E-5 1.938E-4 3.970E-4 12 266
20 M4065 Down-regulated at 24 h following infection of primary human foreskin fibroblasts with CMV MSigDB C2: CGP Curated Gene Sets (v5.1) 7.057E-8 2.104E-5 1.952E-4 4.232E-4 8 91
21 M14555 Down-regulated at any timepoint following infection of primary human foreskin fibroblasts with CMV MSigDB C2: CGP Curated Gene Sets (v5.1) 7.368E-8 2.104E-5 1.952E-4 4.419E-4 9 128
22 M1576 Selected genes down-regulated during differentiation of 3T3-L1 cells (fibroblast) into adipocytes in response to adipogenic hormones. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.046E-7 2.850E-5 2.644E-4 6.270E-4 7 64
23 M1804 Genes up-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [GeneID=6605] off a retroviral vector. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.157E-7 3.016E-5 2.798E-4 6.938E-4 12 280
24 M389 Top 50 most-increased mast cell specific genes. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.030E-7 7.292E-5 6.764E-4 1.817E-3 6 46
25 M1484 Genes up-regulated in pancreatic cells from mice with double knockout of E2F1 [GeneID=1869] and E2F2 [GeneID=1870] compared to wild type. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.040E-7 7.292E-5 6.764E-4 1.823E-3 9 151
26 M3076 Genes up-regulated in comparison of healthy CD4 [GeneID=920] T cells versus healthy CD19 [GeneID=920] B cells. MSigDB C7: Immunologic Signatures (v5.1) 3.363E-7 7.470E-5 6.929E-4 2.017E-3 10 200
27 M5600 Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells versus those treated with IL1B [GeneID=3553] and IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v5.1) 3.363E-7 7.470E-5 6.929E-4 2.017E-3 10 200
28 M2293 Genes down-regulated in ES (embryonic stem cells) with defficient SUZ12 [GeneID=23512]. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.099E-7 8.732E-5 8.100E-4 2.458E-3 12 315
29 M12225 Up-regulated genes in angioimmunoblastic lymphoma (AILT) compared to normal T lymphocytes. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.223E-7 8.732E-5 8.100E-4 2.532E-3 10 205
30 M2680 Genes up-regulated in HEK293 cells (kidney fibroblasts) expressing constitutively active form of CTNNB1 [Gene ID=1499] gene. MSigDB C6: Oncogenic Signatures (v5.1) 4.458E-7 8.911E-5 8.266E-4 2.673E-3 6 49
31 M4008 Genes which best discriminate between two groups of breast cancer according to the status of ESR1 and AR [GeneID=2099;367]: apocrine (ESR1- AR+) and luminal (ESR1+ AR+). MSigDB C2: CGP Curated Gene Sets (v5.1) 5.898E-7 1.141E-4 1.058E-3 3.537E-3 12 326
32 M7514 Genes down-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [GeneID=387] off plasmid vector. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.754E-7 1.266E-4 1.174E-3 4.050E-3 13 394
33 M1124 Pubertal genes up-regulated by TGFB1 [GeneID=7040]. MSigDB C2: CGP Curated Gene Sets (v5.1) 7.861E-7 1.429E-4 1.325E-3 4.714E-3 9 169
34 M8689 Top 200 marker genes down-regulated in the 'CTNNB1' subclass of hepatocellular carcinoma (HCC); characterized by activated CTNNB1 [GeneID=1499]. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.260E-7 1.434E-4 1.330E-3 4.953E-3 9 170
35 M2504 Genes whose expression changes in Calu-6 cells (lung cancer) by TNF [GeneID=7124] were not affected by p38 inhibitor LY479754. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.369E-7 1.434E-4 1.330E-3 5.019E-3 12 337
36 M18322 Genes up-regulated in RD-EF cells (rhabdomyosarcoma) engineered to express EWSR1-FLI1 fusion [GeneID=2130;2313] and which are also highly expressed in Ewing's famliy tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.494E-7 1.582E-4 1.467E-3 5.694E-3 7 88
37 M2857 Genes up-regulated in SKM-1 cells (AML) after knockdown of STK33 [Gene ID=65975] by RNAi. MSigDB C6: Oncogenic Signatures (v5.1) 1.046E-6 1.648E-4 1.529E-3 6.273E-3 11 283
38 M19391 Genes down-regulated in prostate cancer samples. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.070E-6 1.648E-4 1.529E-3 6.415E-3 14 480
39 M2256 Genes commonly down-regulated in UET-13 cells (mesenchymal progenitor) by expression of EWSR1 [GeneID=2130] fusions with ETS transcription factors FLI1 and ERG [GeneID=2313 ,2078]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.072E-6 1.648E-4 1.529E-3 6.427E-3 10 227
40 M14553 Genes up-regulated in LD419 cells (fibroblast) after treatment with decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.217E-6 1.824E-4 1.692E-3 7.298E-3 5 32
41 M2573 Genes consistently up-regulated in mammary stem cells both in mouse and human species. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.331E-6 1.947E-4 1.806E-3 7.983E-3 14 489
42 M10582 Genes up-regulated in Ewing family tumors (EFT) compared with normal bone marrow samples. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.427E-6 2.038E-4 1.891E-3 8.560E-3 5 33
43 M15193 Genes up-regulated in pancreatic ductal adenocarcinoma (PDAC) identified in a meta analysis across four independent studies. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.574E-6 2.196E-4 2.037E-3 9.442E-3 12 358
44 M1610 All significantly up-regulated genes in kidney glomeruli isolated from TCF21 [Gene ID=6943] knockout mice. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.698E-6 2.314E-4 2.146E-3 1.018E-2 13 428
45 M14072 Genes regulated by hypoxia, based on literature searches. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.909E-6 2.544E-4 2.360E-3 1.145E-2 10 242
46 M7396 Genes down-regulated in the Kras2LA mouse lung cancer model with mutated KRAS [GeneID=3845]. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.030E-6 2.647E-4 2.455E-3 1.217E-2 13 435
47 M10952 Genes up-regulated in the atria of healthy hearts, compared to venticles. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.465E-6 3.145E-4 2.918E-3 1.478E-2 10 249
48 M3996 Genes up-regulated in RPTEC cells (normal kidney) by hypoxia. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.533E-6 3.165E-4 2.936E-3 1.519E-2 11 310
49 M10454 Genes up-regulated in pulpal tissue extracted from carious teeth. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.743E-6 3.358E-4 3.115E-3 1.645E-2 10 252
50 M5490 Up-regulated by induction of exogenous BRCA1 in EcR-293 cells MSigDB C2: CGP Curated Gene Sets (v5.1) 2.922E-6 3.466E-4 3.215E-3 1.753E-2 9 198
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 3051 annotations before applied cutoff / 20974 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GSM777055 500 Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4 Immgen.org, GSE15907 5.333E-18 1.627E-14 1.400E-13 1.627E-14 26 455
2 GSM777050 500 Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5 Immgen.org, GSE15907 1.158E-16 1.767E-13 1.520E-12 3.534E-13 25 467
3 GSM777046 500 Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4 Immgen.org, GSE15907 3.009E-16 3.060E-13 2.632E-12 9.180E-13 24 438
4 GSM777067 500 Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2 Immgen.org, GSE15907 6.406E-16 4.886E-13 4.202E-12 1.954E-12 24 453
5 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 500 dev lower uro neuro e15.5 PelvicGanglion Sox10 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.615E-13 9.857E-11 8.478E-10 4.928E-10 20 372
6 endothelial Top 500 All endothelial Top 500 All Brain Map - Barres 4.313E-13 2.193E-10 1.886E-9 1.316E-9 22 496
7 54Dn SubClass 54Dn 1SK Top 500 All 54Dn SubClass 54Dn 1SK Top 500 All Brain Map - Allen iN 9.337E-13 4.070E-10 3.500E-9 2.849E-9 21 461
8 GSM777043 500 Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3 Immgen.org, GSE15907 3.809E-11 1.453E-8 1.249E-7 1.162E-7 19 445
9 gudmap developingGonad P2 epididymis 1000 k5 DevelopingGonad P2 epididymis emap-30199 k-means-cluster#5 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 7.769E-11 2.561E-8 2.203E-7 2.370E-7 12 141
10 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 k4 1000 dev lower uro neuro e15.5 PelvicGanglion Sox10 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 8.395E-11 2.561E-8 2.203E-7 2.561E-7 15 261
11 DevelopingLowerUrinaryTract e14.5 bladder emap-6668 500 DevelopingLowerUrinaryTract e14.5 bladder emap-6668 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.323E-10 3.670E-8 3.157E-7 4.037E-7 18 422
12 gudmap kidney adult RenalCapsule k2 1000 kidney adult RenalCapsule k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.494E-10 3.797E-8 3.266E-7 4.557E-7 17 371
13 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 k2 500 dev lower uro neuro e15.5 PelvicGanglion Sox10 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 4.087E-10 9.592E-8 8.249E-7 1.247E-6 11 127
14 GSM777046 100 Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4 Immgen.org, GSE15907 4.697E-10 1.024E-7 8.804E-7 1.433E-6 10 97
15 PCBC ratio SC-fibro vs SC-cbCD34 100 ratio StemCell-fibro vs StemCell-derived-from CD34-iPSC top-relative-expression-ranked 100 PCBC 5.204E-10 1.058E-7 9.104E-7 1.588E-6 10 98
16 gudmap kidney P4 CapMesRenVes Crym k4 200 kidney P4 CapMesRenVes Crym k-means-cluster#4 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 5.907E-10 1.126E-7 9.688E-7 1.802E-6 6 17
17 80Dn Top 500 All 80Dn Top 500 All Brain Map - Allen iN 1.644E-9 2.950E-7 2.538E-6 5.016E-6 18 494
18 gudmap developingGonad e18.5 epididymis 500 DevelopingGonad e18.5 epididymis emap-13166 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 4.547E-9 7.580E-7 6.519E-6 1.387E-5 16 405
19 gudmap kidney e15.5 Podocyte MafB k2 1000 kidney e15.5 Podocyte MafB k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.720E-9 7.580E-7 6.519E-6 1.440E-5 9 90
20 gudmap developingGonad e18.5 epididymis 500 k2 DevelopingGonad e18.5 epididymis emap-13166 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 5.798E-9 8.321E-7 7.157E-6 1.769E-5 8 64
21 gudmap dev gonad e11.5 F GonadVasMes Flk k3 1000 dev gonad e11.5 F GonadVasMes Flk k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 5.803E-9 8.321E-7 7.157E-6 1.771E-5 15 355
22 gudmap kidney e15.5 Podocyte MafB 500 kidney e15.5 Podocyte MafB top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 6.000E-9 8.321E-7 7.157E-6 1.831E-5 16 413
23 gudmap developingLowerUrinaryTract e14.5 bladder 500 DevelopingLowerUrinaryTract e14.5 bladder emap-30872 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 7.869E-9 1.044E-6 8.978E-6 2.401E-5 16 421
24 gudmap dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 500 dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 8.413E-9 1.069E-6 9.198E-6 2.567E-5 16 423
25 PCBC ratio EB-blastocyst vs EB-cbCD34 100 ratio EmbryoidBody-blastocyst vs EmbryoidBody-derived-from CD34-iPSC top-relative-expression-ranked 100 PCBC 9.210E-9 1.124E-6 9.667E-6 2.810E-5 9 97
26 PCBC ratio EB-fibro vs EB-cbCD34 100 ratio EmbryoidBody-fibro vs EmbryoidBody-derived-from CD34-iPSC top-relative-expression-ranked 100 PCBC 1.009E-8 1.184E-6 1.018E-5 3.078E-5 9 98
27 gudmap dev gonad e13.5 F VascAssocMesenchStromOvary MafB k2 1000 dev gonad e13.5 F VascAssocMesenchStromOvary MafB k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 1.146E-8 1.268E-6 1.091E-5 3.497E-5 13 266
28 PCBC ctl CardiacMyocyte 500 Progenitor-Cell-Biology-Consortium reference CardiacMyocyte top-relative-expression-ranked 500 PCBC 1.164E-8 1.268E-6 1.091E-5 3.552E-5 17 495
29 gudmap dev lower uro neuro e14.5 PelvicGanglion Sox10 500 dev lower uro neuro e14.5 PelvicGanglion Sox10 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 2.976E-8 3.118E-6 2.682E-5 9.079E-5 16 463
30 JC fibro 1000 K1 JC fibro top-relative-expression-ranked 1000 k-means-cluster#1 PCBC 3.066E-8 3.118E-6 2.682E-5 9.354E-5 16 464
31 Lungmap Mouse e16.5 Matrix fibroblast Top 500 All Mouse Lung E16.5 Matrix Fibroblast top 500 Lungmap Mouse Single Cell (Lungmap.net) 5.403E-8 5.317E-6 4.573E-5 1.648E-4 15 420
32 gudmap developingLowerUrinaryTract e13.5 bladder neck-urethr mesench 500 DevelopingLowerUrinaryTract e13.5 bladder neck-urethr mesench emap-3087 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 6.115E-8 5.830E-6 5.014E-5 1.866E-4 15 424
33 JC fibro 500 K3 JC fibro top-relative-expression-ranked 500 k-means-cluster#3 PCBC 6.584E-8 6.087E-6 5.235E-5 2.009E-4 11 206
34 endothelial SubClass DCN-hi Top 500 All endothelial SubClass DCN-hi Top 500 All Brain Map - Barres 7.469E-8 6.536E-6 5.622E-5 2.279E-4 16 495
35 gudmap dev gonad e11.5 M GonMes Sma k3 1000 dev gonad e11.5 M GonMes Sma k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 7.498E-8 6.536E-6 5.622E-5 2.288E-4 13 312
36 54Dn SubClass 54Dn 1SK Top 500 Cluster 2 54Dn SubClass 54Dn 1SK Top 500 Cluster 2 Brain Map - Allen iN 9.927E-8 8.267E-6 7.110E-5 3.029E-4 12 265
37 gudmap dev gonad e11.5 F GonadVasMes Flk k1 200 dev gonad e11.5 F GonadVasMes Flk k-means-cluster#1 top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 1.002E-7 8.267E-6 7.110E-5 3.059E-4 6 37
38 gudmap kidney e15.5 Podocyte MafB k3 200 kidney e15.5 Podocyte MafB k-means-cluster#3 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 1.218E-7 9.781E-6 8.413E-5 3.717E-4 5 20
39 gudmap kidney adult RenalCapsule 200 kidney adult RenalCapsule top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 1.498E-7 1.172E-5 1.008E-4 4.572E-4 10 176
40 gudmap kidney P0 JuxtaGlom Ren1 500 kidney P0 JuxtaGlom Ren1 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.569E-7 1.188E-5 1.021E-4 4.788E-4 15 456
41 GSM777043 100 Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3 Immgen.org, GSE15907 1.596E-7 1.188E-5 1.021E-4 4.869E-4 8 97
42 gudmap dev gonad e11.5 M GonadVasMes Flk k1 1000 dev gonad e11.5 M GonadVasMes Flk k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 1.890E-7 1.373E-5 1.181E-4 5.767E-4 13 338
43 gudmap developingGonad e18.5 epididymis 1000 k5 DevelopingGonad e18.5 epididymis emap-13166 k-means-cluster#5 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 2.389E-7 1.695E-5 1.458E-4 7.288E-4 11 234
44 gudmap developingKidney e15.5 Pelvic Mesenchyme 500 DevelopingKidney e15.5 Pelvic Mesenchyme emap-8241 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 2.825E-7 1.937E-5 1.666E-4 8.619E-4 14 412
45 gudmap developingGonad P2 epididymis 500 k1 DevelopingGonad P2 epididymis emap-30199 k-means-cluster#1 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 2.857E-7 1.937E-5 1.666E-4 8.716E-4 7 71
46 gudmap developingLowerUrinaryTract e14.5 urogenital sinus 500 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-5517 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.267E-7 2.167E-5 1.864E-4 9.969E-4 14 417
47 gudmap kidney adult RenalCapsule k1 500 kidney adult RenalCapsule k-means-cluster#1 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.343E-7 2.170E-5 1.866E-4 1.020E-3 11 242
48 Lungmap Mouse e16.5 Myofibro Top 500 All Lungmap Mouse e16.5 Myofibro Top 500 All Lungmap Mouse Single Cell (Lungmap.net) 3.562E-7 2.232E-5 1.920E-4 1.087E-3 14 420
49 gudmap dev gonad e13.5 F VascAssocMesenchStromOvary MafB 500 dev gonad e13.5 F VascAssocMesenchStromOvary MafB top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 3.643E-7 2.232E-5 1.920E-4 1.111E-3 13 358
50 gudmap dev lower uro neuro e14.5 PelvicGanglion Sox10 200 dev lower uro neuro e14.5 PelvicGanglion Sox10 top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 3.702E-7 2.232E-5 1.920E-4 1.129E-3 10 194
Show 45 more annotations

15: Computational [Display Chart] 347 annotations before applied cutoff / 9399 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 module 12 Genes in module 12 MSigDb: C4 - CM: Cancer Modules 5.271E-11 1.829E-8 1.176E-7 1.829E-8 21 351
2 module 47 Genes in module 47 MSigDb: C4 - CM: Cancer Modules 5.490E-9 9.525E-7 6.123E-6 1.905E-6 15 216
3 module 19 Genes in module 19 MSigDb: C4 - CM: Cancer Modules 1.470E-8 1.700E-6 1.093E-5 5.100E-6 17 307
4 module 1 Genes in module 1 MSigDb: C4 - CM: Cancer Modules 2.683E-8 2.327E-6 1.496E-5 9.308E-6 18 361
5 module 2 Genes in module 2 MSigDb: C4 - CM: Cancer Modules 5.436E-8 3.773E-6 2.425E-5 1.886E-5 18 378
6 module 5 Genes in module 5 MSigDb: C4 - CM: Cancer Modules 1.463E-6 8.461E-5 5.439E-4 5.077E-4 17 423
7 module 52 Genes in module 52 MSigDb: C4 - CM: Cancer Modules 1.042E-4 5.167E-3 3.321E-2 3.617E-2 14 419
8 module 118 Genes in module 118 MSigDb: C4 - CM: Cancer Modules 2.182E-4 9.466E-3
6.085E-2
7.573E-2
 13 395
9 module 6 Genes in module 6 MSigDb: C4 - CM: Cancer Modules 2.922E-4 1.127E-2
7.243E-2
1.014E-1
 13 407
10 module 128 Genes in module 128 MSigDb: C4 - CM: Cancer Modules 5.354E-4 1.724E-2
1.108E-1
1.858E-1
 6 98
11 module 79 Genes in module 79 MSigDb: C4 - CM: Cancer Modules 5.963E-4 1.724E-2
1.108E-1
2.069E-1
 6 100
12 module 170 Genes in module 170 MSigDb: C4 - CM: Cancer Modules 5.963E-4 1.724E-2
1.108E-1
2.069E-1
 6 100
13 module 44 Genes in module 44 MSigDb: C4 - CM: Cancer Modules 1.749E-3 4.670E-2
3.002E-1
6.071E-1
 10 319
Show 8 more annotations

16: MicroRNA [Display Chart] 1178 annotations before applied cutoff / 19844 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 miR-203:PicTar miR-203:PicTar PicTar 1.058E-5 5.197E-3 3.975E-2 1.246E-2 11 330
2 hsa-miR-132:PITA hsa-miR-132:PITA TOP PITA 1.323E-5 5.197E-3 3.975E-2 1.559E-2 11 338
3 hsa-miR-212:PITA hsa-miR-212:PITA TOP PITA 1.323E-5 5.197E-3 3.975E-2 1.559E-2 11 338
4 hsa-miR-623:PITA hsa-miR-623:PITA TOP PITA 2.157E-5 6.354E-3 4.860E-2 2.541E-2 7 129
5 hsa-miR-455-3p:PITA hsa-miR-455-3p:PITA TOP PITA 4.586E-5 8.695E-3
6.651E-2
5.403E-2
 9 256
6 TACAATC,MIR-508:MSigDB TACAATC,MIR-508:MSigDB MSigDB 4.773E-5 8.695E-3
6.651E-2
5.623E-2
 5 61
7 hsa-miR-363:PITA hsa-miR-363:PITA TOP PITA 7.963E-5 8.695E-3
6.651E-2
9.380E-2
 12 486
8 hsa-miR-25:PITA hsa-miR-25:PITA TOP PITA 8.120E-5 8.695E-3
6.651E-2
9.565E-2
 12 487
9 hsa-miR-92a:PITA hsa-miR-92a:PITA TOP PITA 8.120E-5 8.695E-3
6.651E-2
9.565E-2
 12 487
10 hsa-miR-367:PITA hsa-miR-367:PITA TOP PITA 8.120E-5 8.695E-3
6.651E-2
9.565E-2
 12 487
11 hsa-miR-92b:PITA hsa-miR-92b:PITA TOP PITA 8.120E-5 8.695E-3
6.651E-2
9.565E-2
 12 487
12 hsa-miR-654-3p:PITA hsa-miR-654-3p:PITA TOP PITA 9.403E-5 9.231E-3
7.061E-2
1.108E-1
 8 219
13 hsa-miR-380:PITA hsa-miR-380:PITA TOP PITA 2.781E-4 2.520E-2
1.928E-1
3.276E-1
 10 398
14 hsa-miR-32:PITA hsa-miR-32:PITA TOP PITA 3.029E-4 2.548E-2
1.949E-1
3.568E-1
 11 480
15 hsa-miR-503:TargetScan hsa-miR-503:TargetScan TargetScan 4.971E-4 3.092E-2
2.365E-1
5.855E-1
 8 280
16 hsa-miR-155:TargetScan hsa-miR-155:TargetScan TargetScan 5.089E-4 3.092E-2
2.365E-1
5.995E-1
 8 281
17 hsa-miR-362-3p:PITA hsa-miR-362-3p:PITA TOP PITA 5.201E-4 3.092E-2
2.365E-1
6.126E-1
 7 215
18 hsa-miR-329:PITA hsa-miR-329:PITA TOP PITA 5.201E-4 3.092E-2
2.365E-1
6.126E-1
 7 215
19 hsa-miR-421:PITA hsa-miR-421:PITA TOP PITA 5.288E-4 3.092E-2
2.365E-1
6.229E-1
 9 355
20 hsa-miR-576-5p:PITA hsa-miR-576-5p:PITA TOP PITA 5.486E-4 3.092E-2
2.365E-1
6.462E-1
 10 434
21 CAAGGAT,MIR-362:MSigDB CAAGGAT,MIR-362:MSigDB MSigDB 5.512E-4 3.092E-2
2.365E-1
6.493E-1
 4 58
22 hsa-miR-1264:PITA hsa-miR-1264:PITA TOP PITA 7.626E-4 4.031E-2
3.084E-1
8.983E-1
 10 453
23 hsa-miR-562:PITA hsa-miR-562:PITA TOP PITA 7.871E-4 4.031E-2
3.084E-1
9.272E-1
 6 167
24 hsa-miR-875-3p:PITA hsa-miR-875-3p:PITA TOP PITA 8.291E-4 4.069E-2
3.112E-1
9.767E-1
 10 458
25 ATACCTC,MIR-202:MSigDB ATACCTC,MIR-202:MSigDB MSigDB 8.635E-4 4.069E-2
3.112E-1
1.000E0
 6 170
26 hsa-miR-323-3p:PITA hsa-miR-323-3p:PITA TOP PITA 9.233E-4 4.183E-2
3.200E-1
1.000E0
 9 384
27 hsa-miR-1294:PITA hsa-miR-1294:PITA TOP PITA 1.003E-3 4.228E-2
3.234E-1
1.000E0
 6 175
28 miR-25:PicTar miR-25:PicTar PicTar 1.005E-3 4.228E-2
3.234E-1
1.000E0
 8 312
29 hsa-miR-26a:miRTarbase hsa-miR-26a:miRTarbase miRTarbase 1.160E-3 4.607E-2
3.524E-1
1.000E0
 3 32
30 miR-145:PicTar miR-145:PicTar PicTar 1.173E-3 4.607E-2
3.524E-1
1.000E0
 7 247
31 hsa-let-7a:miRTarbase hsa-let-7a:miRTarbase miRTarbase 1.270E-3 4.825E-2
3.691E-1
1.000E0
 3 33
32 hsa-miR-382:TargetScan hsa-miR-382:TargetScan TargetScan 1.450E-3 4.947E-2
3.784E-1
1.000E0
 5 127
33 hsa-miR-18a:TargetScan hsa-miR-18a:TargetScan TargetScan 1.489E-3 4.947E-2
3.784E-1
1.000E0
 6 189
34 hsa-miR-18b:TargetScan hsa-miR-18b:TargetScan TargetScan 1.489E-3 4.947E-2
3.784E-1
1.000E0
 6 189
35 hsa-miR-18a:PITA hsa-miR-18a:PITA TOP PITA 1.530E-3 4.947E-2
3.784E-1
1.000E0
 6 190
36 hsa-miR-18b:PITA hsa-miR-18b:PITA TOP PITA 1.530E-3 4.947E-2
3.784E-1
1.000E0
 6 190
37 AGCATTA,MIR-155:MSigDB AGCATTA,MIR-155:MSigDB MSigDB 1.554E-3 4.947E-2
3.784E-1
1.000E0
 5 129
38 hsa-miR-21:miRTarbase hsa-miR-21:miRTarbase miRTarbase 1.599E-3 4.956E-2
3.791E-1
1.000E0
 4 77
Show 33 more annotations

17: Drug [Display Chart] 20998 annotations before applied cutoff / 22098 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000072194 2-chlorodideoxyadenosine Stitch 1.408E-10 2.956E-6 3.112E-5 2.956E-6 8 43
2 CID000015759 p11-13 Stitch 5.773E-10 6.061E-6 6.382E-5 1.212E-5 9 75
3 D015056 1-Methyl-3-isobutylxanthine CTD 1.064E-8 7.447E-5 7.841E-4 2.234E-4 15 391
4 3968 UP PHA-00851261E [724719-49-7]; Up 200; 1uM; MCF7; HT HG-U133A Broad Institute CMAP 2.882E-8 1.229E-4 1.294E-3 6.051E-4 11 200
5 C113580 U 0126 CTD 2.926E-8 1.229E-4 1.294E-3 6.144E-4 15 422
6 CID000005090 rofecoxib Stitch 5.491E-8 1.922E-4 2.023E-3 1.153E-3 9 125
7 C031721 naphthalene CTD 9.313E-8 2.794E-4 2.942E-3 1.956E-3 14 396
8 6711 UP Puromycin dihydrochloride [58-58-2]; Up 200; 7.4uM; PC3; HT HG-U133A Broad Institute CMAP 1.089E-7 2.858E-4 3.009E-3 2.286E-3 10 179
9 D004391 Dust CTD 1.555E-7 3.417E-4 3.598E-3 3.265E-3 11 236
10 CID000001620 AC1L1BV0 Stitch 1.627E-7 3.417E-4 3.598E-3 3.417E-3 6 42
11 D005944 Glucosamine CTD 2.694E-7 4.876E-4 5.134E-3 5.656E-3 12 306
12 1497 UP Antipyrine, 4-hydroxy [1672-63-5]; Up 200; 19.6uM; MCF7; HT HG-U133A Broad Institute CMAP 2.786E-7 4.876E-4 5.134E-3 5.851E-3 10 198
13 C002802 tungsten carbide CTD 3.478E-7 5.354E-4 5.638E-3 7.304E-3 9 155
14 6764 UP Anisomycin [22862-76-6]; Up 200; 15uM; PC3; HT HG-U133A Broad Institute CMAP 3.877E-7 5.354E-4 5.638E-3 8.142E-3 9 157
15 CID000446400 sPLA2 inhibitor Stitch 3.885E-7 5.354E-4 5.638E-3 8.158E-3 5 26
16 2429 UP Cephaeline dihydrochloride heptahydrate [6487-30-5]; Up 200; 6uM; HL60; HT HG-U133A Broad Institute CMAP 4.550E-7 5.354E-4 5.638E-3 9.555E-3 9 160
17 D003345 Corticosterone CTD 4.590E-7 5.354E-4 5.638E-3 9.638E-3 11 263
18 D008769 Methylnitronitrosoguanidine CTD 4.590E-7 5.354E-4 5.638E-3 9.638E-3 11 263
19 CID000066393 estradiol-2,3-quinone Stitch 6.988E-7 7.570E-4 7.971E-3 1.467E-2 7 85
20 D016559 Tacrolimus CTD 7.504E-7 7.570E-4 7.971E-3 1.576E-2 12 337
21 D016291 Dizocilpine Maleate CTD 7.570E-7 7.570E-4 7.971E-3 1.590E-2 7 86
22 1381 UP Terfenadine [50679-08-8]; Up 200; 8.4uM; HL60; HG-U133A Broad Institute CMAP 8.357E-7 7.962E-4 8.384E-3 1.755E-2 9 172
23 CID000004253 morphine hydrochloride Stitch 9.698E-7 7.962E-4 8.384E-3 2.036E-2 14 481
24 D008550 Melatonin CTD 9.758E-7 7.962E-4 8.384E-3 2.049E-2 10 227
25 CID000024766 chondroitin sulfate Stitch 1.018E-6 7.962E-4 8.384E-3 2.138E-2 13 413
26 D002211 Capsaicin CTD 1.044E-6 7.962E-4 8.384E-3 2.191E-2 14 484
27 CID011957435 azafagomine Stitch 1.047E-6 7.962E-4 8.384E-3 2.199E-2 6 57
28 3060 UP Digoxigenin [1672-46-4]; Up 200; 10.2uM; HL60; HT HG-U133A Broad Institute CMAP 1.062E-6 7.962E-4 8.384E-3 2.229E-2 9 177
29 4662 UP Menadione [58-27-5]; Up 200; 23.2uM; PC3; HT HG-U133A Broad Institute CMAP 1.279E-6 9.260E-4 9.750E-3 2.685E-2 9 181
30 D002857 Chromium CTD 1.555E-6 1.088E-3 1.146E-2 3.265E-2 10 239
31 C059765 amphotericin B, deoxycholate drug combination CTD 1.728E-6 1.171E-3 1.233E-2 3.629E-2 12 365
32 C025340 manganese chloride CTD 2.286E-6 1.500E-3 1.580E-2 4.801E-2 12 375
33 4738 UP Graveoline [485-61-0]; Up 200; 14.4uM; MCF7; HT HG-U133A Broad Institute CMAP 2.368E-6 1.507E-3 1.587E-2 4.973E-2 9 195
34 6619 UP Tracazolate hydrochloride [41094-88-6]; Up 200; 11.8uM; PC3; HT HG-U133A Broad Institute CMAP 2.576E-6 1.591E-3 1.675E-2
5.408E-2
 9 197
35 CID000003541 AC1MBZ1C Stitch 3.161E-6 1.849E-3 1.947E-2
6.638E-2
 12 387
36 2448 UP Puromycin dihydrochloride [58-58-2]; Up 200; 7.4uM; HL60; HT HG-U133A Broad Institute CMAP 3.171E-6 1.849E-3 1.947E-2
6.658E-2
 8 151
37 3808 UP Lycorine hydrochloride [2188-68-3]; Up 200; 12.4uM; PC3; HT HG-U133A Broad Institute CMAP 3.497E-6 1.985E-3 2.090E-2
7.343E-2
 8 153
38 C063509 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide CTD 3.852E-6 2.043E-3 2.151E-2
8.087E-2
 8 155
39 CID000123682 SKF 94120 Stitch 3.928E-6 2.043E-3 2.151E-2
8.248E-2
 3 6
40 D014701 Veratridine CTD 3.928E-6 2.043E-3 2.151E-2
8.248E-2
 3 6
41 D009543 Nifedipine CTD 3.989E-6 2.043E-3 2.151E-2
8.377E-2
 7 110
42 1304 UP Anisomycin [22862-76-6]; Up 200; 15uM; HL60; HT HG-U133A Broad Institute CMAP 4.236E-6 2.118E-3 2.230E-2
8.895E-2
 8 157
43 CID000123723 BAY X 1005 Stitch 5.247E-6 2.562E-3 2.698E-2
1.102E-1
 5 43
44 CID000004534 NDGA Stitch 5.461E-6 2.606E-3 2.744E-2
1.147E-1
 9 216
45 2145 UP Emetine dihydrochloride [316-42-7]; Up 200; 7.2uM; HL60; HT HG-U133A Broad Institute CMAP 5.590E-6 2.608E-3 2.747E-2
1.174E-1
 8 163
46 CID000002683 cetylpyridinium chloride Stitch 5.892E-6 2.690E-3 2.832E-2
1.237E-1
 5 44
47 3770 UP Helveticoside [630-64-8]; Up 200; 7.4uM; PC3; HT HG-U133A Broad Institute CMAP 6.116E-6 2.732E-3 2.877E-2
1.284E-1
 8 165
48 4327 UP Helveticoside [630-64-8]; Up 200; 7.4uM; PC3; HT HG-U133A Broad Institute CMAP 6.394E-6 2.740E-3 2.885E-2
1.343E-1
 8 166
49 5826 UP Strophanthidin [66-28-4]; Up 200; 9.8uM; PC3; HT HG-U133A Broad Institute CMAP 6.394E-6 2.740E-3 2.885E-2
1.343E-1
 8 166
50 1626 UP Etoposide [33419-42-0]; Up 200; 6.8uM; HL60; HG-U133A Broad Institute CMAP 6.683E-6 2.764E-3 2.910E-2
1.403E-1
 8 167
Show 45 more annotations

18: Disease [Display Chart] 2187 annotations before applied cutoff / 16150 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 umls:C2936349 Plaque, Amyloid DisGeNET Curated 2.608E-6 2.429E-3 2.008E-2 5.704E-3 10 207
2 umls:C1704272 Benign Prostatic Hyperplasia DisGeNET BeFree 3.058E-6 2.429E-3 2.008E-2 6.689E-3 13 373
3 umls:C0008497 Choriocarcinoma DisGeNET BeFree 3.525E-6 2.429E-3 2.008E-2 7.710E-3 11 265
4 umls:C0239946 Fibrosis, Liver DisGeNET BeFree 4.442E-6 2.429E-3 2.008E-2 9.716E-3 12 327
5 umls:C1153706 Endometrial adenocarcinoma DisGeNET BeFree 9.758E-6 4.268E-3 3.529E-2 2.134E-2 7 103
6 umls:C0038356 Stomach Neoplasms DisGeNET Curated 1.226E-5 4.470E-3 3.695E-2 2.682E-2 14 490
7 umls:C0022548 Keloid DisGeNET Curated 2.775E-5 7.769E-3
6.423E-2
6.069E-2
 8 166
8 umls:C3203102 Idiopathic pulmonary arterial hypertension DisGeNET Curated 2.842E-5 7.769E-3
6.423E-2
6.215E-2
 6 82
9 umls:C0559031 Functional Gastrointestinal Disorders DisGeNET BeFree 5.861E-5 1.424E-2
1.177E-1
1.282E-1
 3 11
10 umls:C1519670 Tumor Angiogenesis DisGeNET BeFree 8.876E-5 1.941E-2
1.605E-1
1.941E-1
 12 443
11 umls:C0740457 Malignant neoplasm of kidney DisGeNET BeFree 1.109E-4 2.036E-2
1.683E-1
2.425E-1
 11 385
12 umls:C0206638 Giant Cell Tumor of Bone DisGeNET Curated 1.327E-4 2.036E-2
1.683E-1
2.901E-1
 5 68
13 umls:C0206624 Hepatoblastoma DisGeNET Curated 1.450E-4 2.036E-2
1.683E-1
3.172E-1
 8 210
14 umls:C3266843 47, XYY syndrome DisGeNET BeFree 1.554E-4 2.036E-2
1.683E-1
3.398E-1
 2 3
15 umls:C1568363 Tendinosis DisGeNET BeFree 1.582E-4 2.036E-2
1.683E-1
3.461E-1
 3 15
16 umls:C0334287 Fibrolamellar hepatocellular carcinoma DisGeNET BeFree 1.582E-4 2.036E-2
1.683E-1
3.461E-1
 3 15
17 umls:C0393570 Corticobasal degeneration DisGeNET BeFree 1.582E-4 2.036E-2
1.683E-1
3.461E-1
 3 15
18 cv:C1839071 Spermatogenic failure, Y-linked 2 Clinical Variations 1.937E-4 2.225E-2
1.840E-1
4.237E-1
 3 16
19 umls:C0555198 Malignant Glioma DisGeNET BeFree 2.004E-4 2.225E-2
1.840E-1
4.382E-1
 11 412
20 umls:C0152171 Idiopathic pulmonary hypertension DisGeNET Curated 2.121E-4 2.225E-2
1.840E-1
4.639E-1
 8 222
21 umls:C0151514 Atrophic condition of skin DisGeNET BeFree 2.165E-4 2.225E-2
1.840E-1
4.735E-1
 6 118
22 umls:C0879615 Stromal Neoplasm DisGeNET BeFree 2.245E-4 2.225E-2
1.840E-1
4.911E-1
 5 76
23 415000 SPERMATOGENIC FAILURE, NONOBSTRUCTIVE, Y-LINKED OMIM 2.340E-4 2.225E-2
1.840E-1
5.117E-1
 3 17
24 umls:C0206663 Neuroectodermal Tumor, Primitive DisGeNET Curated 2.712E-4 2.337E-2
1.933E-1
5.930E-1
 6 123
25 umls:C0085648 Synovial Cyst DisGeNET BeFree 2.739E-4 2.337E-2
1.933E-1
5.989E-1
 7 174
26 umls:C0013080 Down Syndrome DisGeNET Curated 2.836E-4 2.337E-2
1.933E-1
6.201E-1
 11 429
27 umls:C0393484 Rasmussen Syndrome DisGeNET BeFree 3.093E-4 2.337E-2
1.933E-1
6.764E-1
 2 4
28 20081125:Plenge Rheumatoid arthritis GWAS 3.093E-4 2.337E-2
1.933E-1
6.764E-1
 2 4
29 umls:C0338831 Manic DisGeNET BeFree 3.099E-4 2.337E-2
1.933E-1
6.779E-1
 4 45
30 umls:C1258666 Myxoid cyst DisGeNET BeFree 3.253E-4 2.371E-2
1.961E-1
7.114E-1
 7 179
31 umls:C0338106 Adenocarcinoma of colon DisGeNET Curated 3.589E-4 2.532E-2
2.093E-1
7.848E-1
 8 240
32 umls:C0027626 Neoplasm Invasiveness DisGeNET Curated 3.963E-4 2.709E-2
2.240E-1
8.668E-1
 6 132
33 umls:C0034069 Pulmonary Fibrosis DisGeNET Curated 4.986E-4 3.206E-2
2.650E-1
1.000E0
 9 317
34 umls:C0007370 Catalepsy DisGeNET Curated 5.161E-4 3.206E-2
2.650E-1
1.000E0
 3 22
35 umls:C0032227 Pleural effusion disorder DisGeNET Curated 5.186E-4 3.206E-2
2.650E-1
1.000E0
 5 91
36 umls:C0030193 Pain DisGeNET Curated 5.277E-4 3.206E-2
2.650E-1
1.000E0
 7 194
37 umls:C0040128 Thyroid Diseases DisGeNET Curated 5.729E-4 3.311E-2
2.737E-1
1.000E0
 5 93
38 umls:C0042133 Uterine Fibroids DisGeNET Curated 5.833E-4 3.311E-2
2.737E-1
1.000E0
 9 324
39 umls:C0877015 Pelvic Organ Prolapse DisGeNET Curated 5.904E-4 3.311E-2
2.737E-1
1.000E0
 3 23
40 umls:C0235031 Neurologic Symptoms DisGeNET BeFree 6.943E-4 3.722E-2
3.077E-1
1.000E0
 5 97
41 umls:C0149931 Migraine Disorders DisGeNET Curated 7.317E-4 3.722E-2
3.077E-1
1.000E0
 7 205
42 umls:C0278996 Cancer of Head and Neck DisGeNET BeFree 7.367E-4 3.722E-2
3.077E-1
1.000E0
 10 406
43 umls:C0017650 Globus Hystericus DisGeNET BeFree 7.587E-4 3.722E-2
3.077E-1
1.000E0
 3 25
44 umls:C0277524 Infectious colitis DisGeNET BeFree 7.659E-4 3.722E-2
3.077E-1
1.000E0
 2 6
45 umls:C0694550 Recurrent pneumonia DisGeNET BeFree 7.659E-4 3.722E-2
3.077E-1
1.000E0
 2 6
46 umls:C0877373 Advanced cancer DisGeNET BeFree 7.973E-4 3.791E-2
3.134E-1
1.000E0
 5 100
47 umls:C0278488 Carcinoma breast stage IV DisGeNET BeFree 8.393E-4 3.905E-2
3.229E-1
1.000E0
 9 341
48 umls:C0151650 Renal fibrosis DisGeNET BeFree 9.877E-4 4.500E-2
3.721E-1
1.000E0
 6 157
49 umls:C0278506 Non-small cell lung cancer stage III DisGeNET BeFree 1.067E-3 4.549E-2
3.761E-1
1.000E0
 2 7
50 umls:C0001733 Afibrinogenemia DisGeNET Curated 1.067E-3 4.549E-2
3.761E-1
1.000E0
 2 7
Show 45 more annotations