Toppgene analysis for aggregated_1964_log, IC10, positive side

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1: GO: Molecular Function [Display Chart] 721 annotations before applied cutoff / 18819 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding 1.596E-6 1.151E-3 8.237E-3 1.151E-3 16 358

2: GO: Biological Process [Display Chart] 3812 annotations before applied cutoff / 18785 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0001503 ossification 4.988E-7 1.901E-3 1.678E-2 1.901E-3 18 406
2 GO:0007409 axonogenesis 1.230E-6 2.344E-3 2.068E-2 4.688E-3 19 478
3 GO:0045444 fat cell differentiation 7.043E-6 8.949E-3
7.896E-2
 2.685E-2 12 226
4 GO:0021953 central nervous system neuron differentiation 1.287E-5 1.021E-2
9.006E-2
 4.907E-2 11 201
5 GO:0042063 gliogenesis 1.339E-5 1.021E-2
9.006E-2
5.104E-2
 13 282
6 GO:0030278 regulation of ossification 1.695E-5 1.057E-2
9.330E-2
6.462E-2
 11 207
7 GO:0048710 regulation of astrocyte differentiation 1.942E-5 1.057E-2
9.330E-2
7.402E-2
 5 31
8 GO:0030850 prostate gland development 3.855E-5 1.645E-2
1.452E-1
1.469E-1
 6 58
9 GO:0001655 urogenital system development 3.885E-5 1.645E-2
1.452E-1
1.481E-1
 14 358
10 GO:1903115 regulation of actin filament-based movement 4.725E-5 1.801E-2
1.589E-1
1.801E-1
 5 37
11 GO:0030111 regulation of Wnt signaling pathway 5.499E-5 1.897E-2
1.674E-1
2.096E-1
 13 323
12 GO:0045598 regulation of fat cell differentiation 5.972E-5 1.897E-2
1.674E-1
2.277E-1
 8 123
13 GO:0042391 regulation of membrane potential 9.981E-5 2.751E-2
2.427E-1
3.805E-1
 14 391
14 GO:0021957 corticospinal tract morphogenesis 1.010E-4 2.751E-2
2.427E-1
3.851E-1
 3 9
15 GO:0045907 positive regulation of vasoconstriction 1.107E-4 2.754E-2
2.430E-1
4.219E-1
 5 44
16 GO:0097324 melanocyte migration 1.174E-4 2.754E-2
2.430E-1
4.474E-1
 2 2
17 GO:0070252 actin-mediated cell contraction 1.241E-4 2.754E-2
2.430E-1
4.732E-1
 7 102
18 GO:0048708 astrocyte differentiation 1.312E-4 2.754E-2
2.430E-1
5.001E-1
 6 72
19 GO:2001259 positive regulation of cation channel activity 1.373E-4 2.754E-2
2.430E-1
5.233E-1
 5 46
20 GO:0086065 cell communication involved in cardiac conduction 1.523E-4 2.902E-2
2.561E-1
5.805E-1
 5 47
21 GO:0021952 central nervous system projection neuron axonogenesis 1.674E-4 3.030E-2
2.673E-1
6.381E-1
 4 26
22 GO:0001649 osteoblast differentiation 1.749E-4 3.030E-2
2.673E-1
6.666E-1
 10 224
23 GO:0050769 positive regulation of neurogenesis 1.868E-4 3.095E-2
2.731E-1
7.119E-1
 15 467
24 GO:0032414 positive regulation of ion transmembrane transporter activity 2.348E-4 3.147E-2
2.776E-1
8.952E-1
 6 80
25 GO:0086003 cardiac muscle cell contraction 2.469E-4 3.147E-2
2.776E-1
9.412E-1
 5 52
26 GO:1903524 positive regulation of blood circulation 2.479E-4 3.147E-2
2.776E-1
9.451E-1
 7 114
27 GO:0043627 response to estrogen 2.487E-4 3.147E-2
2.776E-1
9.479E-1
 10 234
28 GO:0097696 STAT cascade 2.572E-4 3.147E-2
2.776E-1
9.805E-1
 9 192
29 GO:0007259 JAK-STAT cascade 2.572E-4 3.147E-2
2.776E-1
9.805E-1
 9 192
30 GO:0031953 negative regulation of protein autophosphorylation 2.583E-4 3.147E-2
2.776E-1
9.846E-1
 3 12
31 GO:0032355 response to estradiol 2.601E-4 3.147E-2
2.776E-1
9.914E-1
 8 152
32 GO:0007411 axon guidance 3.146E-4 3.147E-2
2.776E-1
1.000E0
 10 241
33 GO:0097485 neuron projection guidance 3.251E-4 3.147E-2
2.776E-1
1.000E0
 10 242
34 GO:0050900 leukocyte migration 3.280E-4 3.147E-2
2.776E-1
1.000E0
 13 387
35 GO:0086004 regulation of cardiac muscle cell contraction 3.377E-4 3.147E-2
2.776E-1
1.000E0
 4 31
36 GO:0045686 negative regulation of glial cell differentiation 3.377E-4 3.147E-2
2.776E-1
1.000E0
 4 31
37 GO:0021954 central nervous system neuron development 3.482E-4 3.147E-2
2.776E-1
1.000E0
 6 86
38 GO:0019065 receptor-mediated endocytosis of virus by host cell 3.496E-4 3.147E-2
2.776E-1
1.000E0
 2 3
39 GO:1903781 positive regulation of cardiac conduction 3.496E-4 3.147E-2
2.776E-1
1.000E0
 2 3
40 GO:0075509 endocytosis involved in viral entry into host cell 3.496E-4 3.147E-2
2.776E-1
1.000E0
 2 3
41 GO:2000978 negative regulation of forebrain neuron differentiation 3.496E-4 3.147E-2
2.776E-1
1.000E0
 2 3
42 GO:0045600 positive regulation of fat cell differentiation 3.504E-4 3.147E-2
2.776E-1
1.000E0
 5 56
43 GO:0016055 Wnt signaling pathway 3.549E-4 3.147E-2
2.776E-1
1.000E0
 15 496
44 GO:0034766 negative regulation of ion transmembrane transport 3.942E-4 3.241E-2
2.859E-1
1.000E0
 6 88
45 GO:0045667 regulation of osteoblast differentiation 3.943E-4 3.241E-2
2.859E-1
1.000E0
 7 123
46 GO:0046425 regulation of JAK-STAT cascade 3.996E-4 3.241E-2
2.859E-1
1.000E0
 8 162
47 GO:1904892 regulation of STAT cascade 3.996E-4 3.241E-2
2.859E-1
1.000E0
 8 162
48 GO:0048715 negative regulation of oligodendrocyte differentiation 4.205E-4 3.311E-2
2.921E-1
1.000E0
 3 14
49 GO:0060740 prostate gland epithelium morphogenesis 4.318E-4 3.311E-2
2.921E-1
1.000E0
 4 33
50 GO:0030048 actin filament-based movement 4.347E-4 3.311E-2
2.921E-1
1.000E0
 7 125
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 307 annotations before applied cutoff / 19172 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0043204 perikaryon 1.619E-4 3.962E-2
2.498E-1
 4.972E-2 8 144
2 GO:0033267 axon part 5.141E-4 3.962E-2
2.498E-1
1.578E-1
 11 309
3 GO:0070382 exocytic vesicle 5.379E-4 3.962E-2
2.498E-1
1.651E-1
 8 172
4 GO:0005911 cell-cell junction 6.141E-4 3.962E-2
2.498E-1
1.885E-1
 13 420
5 GO:0005667 transcription factor complex 6.453E-4 3.962E-2
2.498E-1
1.981E-1
 12 369

4: Human Phenotype [Display Chart] 619 annotations before applied cutoff / 4410 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 3178 annotations before applied cutoff / 9299 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0008271 abnormal bone ossification 1.707E-6 5.425E-3 4.688E-2 5.425E-3 21 428
2 MP:0000163 abnormal cartilage morphology 1.692E-5 2.689E-2
2.324E-1
5.378E-2
 18 381

6: Domain [Display Chart] 1334 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR009057 Homeodomain-like InterPro 1.745E-5 2.328E-2
1.810E-1
 2.328E-2 14 332
2 PF14497 GST C 3 Pfam 1.443E-4 3.606E-2
2.803E-1
1.925E-1
 3 10
3 SM00284 OLF SMART 3.357E-4 3.606E-2
2.803E-1
4.478E-1
 3 13
4 IPR003112 Olfac-like dom InterPro 3.357E-4 3.606E-2
2.803E-1
4.478E-1
 3 13
5 PS51132 OLF PROSITE 3.357E-4 3.606E-2
2.803E-1
4.478E-1
 3 13
6 PF02191 OLF Pfam 3.357E-4 3.606E-2
2.803E-1
4.478E-1
 3 13
7 IPR022082 Noelin dom InterPro 3.514E-4 3.606E-2
2.803E-1
4.688E-1
 2 3
8 PF01146 Caveolin Pfam 3.514E-4 3.606E-2
2.803E-1
4.688E-1
 2 3
9 PF12308 Noelin-1 Pfam 3.514E-4 3.606E-2
2.803E-1
4.688E-1
 2 3
10 IPR018361 Caveolin CS InterPro 3.514E-4 3.606E-2
2.803E-1
4.688E-1
 2 3
11 IPR020676 DAPK1 InterPro 3.514E-4 3.606E-2
2.803E-1
4.688E-1
 2 3
12 PS01210 CAVEOLIN PROSITE 3.514E-4 3.606E-2
2.803E-1
4.688E-1
 2 3
13 IPR001612 Caveolin InterPro 3.514E-4 3.606E-2
2.803E-1
4.688E-1
 2 3
Show 8 more annotations

7: Pathway [Display Chart] 1038 annotations before applied cutoff / 10916 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 83105 Pathways in cancer BioSystems: KEGG 3.089E-5 3.206E-2
2.412E-1
 3.206E-2 14 327
2 83115 Bladder cancer BioSystems: KEGG 7.829E-5 4.063E-2
3.057E-1
8.126E-2
 5 38
3 161011 Role of DCC in regulating apoptosis BioSystems: REACTOME 1.821E-4 4.608E-2
3.467E-1
1.890E-1
 3 10
4 137914 Presenilin action in Notch and Wnt signaling BioSystems: Pathway Interaction Database 1.982E-4 4.608E-2
3.467E-1
2.058E-1
 5 46
5 P00057 Wnt signaling pathway PantherDB 2.573E-4 4.608E-2
3.467E-1
2.670E-1
 12 305
6 782000 Proteoglycans in cancer BioSystems: KEGG 3.280E-4 4.608E-2
3.467E-1
3.405E-1
 10 225
7 PW:0000363 leptin system Pathway Ontology 3.281E-4 4.608E-2
3.467E-1
3.406E-1
 3 12
8 137976 IL2-mediated signaling events BioSystems: Pathway Interaction Database 3.552E-4 4.608E-2
3.467E-1
3.687E-1
 5 52
Show 3 more annotations

8: Pubmed [Display Chart] 32389 annotations before applied cutoff / 51853 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 19453261 High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Pubmed 4.789E-12 7.755E-8 8.502E-7 1.551E-7 16 383
2 19453261:gr High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. GeneRIF 4.789E-12 7.755E-8 8.502E-7 1.551E-7 16 383
3 20628624 Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". Pubmed 2.254E-9 1.825E-5 2.001E-4 7.301E-5 10 172
4 20628624:gr Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". GeneRIF 2.254E-9 1.825E-5 2.001E-4 7.301E-5 10 172
5 19058789 A common variant in DRD3 receptor is associated with autism spectrum disorder. Pubmed 5.676E-8 3.064E-4 3.359E-3 1.839E-3 8 129
6 19058789:gr A common variant in DRD3 receptor is associated with autism spectrum disorder. GeneRIF 5.676E-8 3.064E-4 3.359E-3 1.839E-3 8 129
7 20634891:gr Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. GeneRIF 1.144E-7 4.631E-4 5.077E-3 3.705E-3 11 331
8 20634891 Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Pubmed 1.144E-7 4.631E-4 5.077E-3 3.705E-3 11 331
9 18828811 Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence. Pubmed 2.501E-7 6.750E-4 7.400E-3 8.100E-3 3 4
10 17948870:gr Chromosome 4q31-34 panic disorder risk locus: association of neuropeptide Y Y5 receptor variants. GeneRIF 2.501E-7 6.750E-4 7.400E-3 8.100E-3 3 4
11 18828811:gr Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence. GeneRIF 2.501E-7 6.750E-4 7.400E-3 8.100E-3 3 4
12 17948870 Chromosome 4q31-34 panic disorder risk locus: association of neuropeptide Y Y5 receptor variants. Pubmed 2.501E-7 6.750E-4 7.400E-3 8.100E-3 3 4
13 12007534 Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status. Pubmed 6.233E-7 1.553E-3 1.703E-2 2.019E-2 3 5
14 17979883:gr Matrix metalloproteinase-2, caveolins, focal adhesion kinase and c-Kit in cells of the mouse myocardium. GeneRIF 1.243E-6 2.516E-3 2.759E-2 4.026E-2 3 6
15 17325259 Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men. Pubmed 1.243E-6 2.516E-3 2.759E-2 4.026E-2 3 6
16 17325259:gr Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men. GeneRIF 1.243E-6 2.516E-3 2.759E-2 4.026E-2 3 6
17 15340161 Signal peptide prediction based on analysis of experimentally verified cleavage sites. Pubmed 1.346E-6 2.564E-3 2.810E-2 4.358E-2 9 264
18 16799092 Dynamic profiling of the post-translational modifications and interaction partners of epidermal growth factor receptor signaling after stimulation by epidermal growth factor using Extended Range Proteomic Analysis (ERPA). Pubmed 2.058E-6 2.777E-3 3.044E-2
6.667E-2
 4 23
19 11756408 Modulation of basic helix-loop-helix transcription complex formation by Id proteins during neuronal differentiation. Pubmed 2.169E-6 2.777E-3 3.044E-2
7.025E-2
 3 7
20 25231870 Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Pubmed 2.534E-6 2.777E-3 3.044E-2
8.208E-2
 7 149
21 18519826:gr Molecular genetics of successful smoking cessation: convergent genome-wide association study results. GeneRIF 3.479E-6 2.777E-3 3.044E-2
1.127E-1
 6 101
22 18519826 Molecular genetics of successful smoking cessation: convergent genome-wide association study results. Pubmed 3.479E-6 2.777E-3 3.044E-2
1.127E-1
 6 101
23 19086053:gr Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. GeneRIF 3.822E-6 2.777E-3 3.044E-2
1.238E-1
 9 300
24 19086053 Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. Pubmed 3.822E-6 2.777E-3 3.044E-2
1.238E-1
 9 300
25 19860791:gr Genetic evidence for a role of IL33 in nasal polyposis. GeneRIF 7.371E-6 2.777E-3 3.044E-2
2.387E-1
 3 10
26 19860791 Genetic evidence for a role of IL33 in nasal polyposis. Pubmed 7.371E-6 2.777E-3 3.044E-2
2.387E-1
 3 10
27 18577758 Dissociation of heterotrimeric g proteins in cells. Pubmed 8.477E-6 2.777E-3 3.044E-2
2.746E-1
 7 179
28 19692168 Genetic susceptibility to distinct bladder cancer subphenotypes. Pubmed 8.825E-6 2.777E-3 3.044E-2
2.858E-1
 10 422
29 19692168:gr Genetic susceptibility to distinct bladder cancer subphenotypes. GeneRIF 8.825E-6 2.777E-3 3.044E-2
2.858E-1
 10 422
30 20468064:gr Association study of 182 candidate genes in anorexia nervosa. GeneRIF 9.447E-6 2.777E-3 3.044E-2
3.060E-1
 7 182
31 20468064 Association study of 182 candidate genes in anorexia nervosa. Pubmed 9.447E-6 2.777E-3 3.044E-2
3.060E-1
 7 182
32 16335952 Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. Pubmed 1.019E-5 2.777E-3 3.044E-2
3.301E-1
 8 257
33 19874574 Genetical genomic determinants of alcohol consumption in rats and humans. Pubmed 1.487E-5 2.777E-3 3.044E-2
4.817E-1
 6 130
34 19874574:gr Genetical genomic determinants of alcohol consumption in rats and humans. GeneRIF 1.487E-5 2.777E-3 3.044E-2
4.817E-1
 6 130
35 16785149:gr Body composition and concentrations of leptin, neuropeptide Y, beta-endorphin, growth hormone, insulin-like growth factor-I and insulin at menarche in girls with constitutional delay of puberty. GeneRIF 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
36 25779942 SLFN11 Is a Transcriptional Target of EWS-FLI1 and a Determinant of Drug Response in Ewing Sarcoma. Pubmed 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
37 16339211 Activation of the Y1 receptor by neuropeptide Y regulates the growth of prostate cancer cells. Pubmed 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
38 17881732:gr Cyclin D1 is transcriptionally down-regulated by ZO-2 via an E box and the transcription factor c-Myc. GeneRIF 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
39 17189626:gr Functions of a jumonji-cyclin D1 pathway in the coordination of cell cycle exit and migration during neurogenesis in the mouse hindbrain. GeneRIF 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
40 17510462:gr Genetic deletion of pregnancy-associated plasma protein-A is associated with resistance to atherosclerotic lesion development in apolipoprotein E-deficient mice challenged with a high-fat diet. GeneRIF 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
41 15611095 Modulation of erythrocyte membrane mechanical function by protein 4.1 phosphorylation. Pubmed 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
42 17671707:gr The overexpression of caveolin-1 and caveolin-2 correlates with a poor prognosis and tumor progression in esophageal squamous cell carcinoma. GeneRIF 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
43 10087206 Human caveolin-1 and caveolin-2 are closely linked genes colocalized with WI-5336 in a region of 7q31 frequently deleted in tumors. Pubmed 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
44 20209490 Association of caveolin-1 and -2 genetic variants and post-treatment serum caveolin-1 with prostate cancer risk and outcomes. Pubmed 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
45 22029806 Expression of Neuropeptide Y, Substance P, and their receptors in the right atrium of diabetic patients. Pubmed 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
46 16174778:gr Cholecystokinin levels in prohormone convertase 2 knock-out mouse brain regions reveal a complex phenotype of region-specific alterations. GeneRIF 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
47 17696648 An actin-based wave generator organizes cell motility. Pubmed 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
48 16174239 Overexpression of cyclin D1 and c-Myc gene products in human primary epithelial ovarian cancer. Pubmed 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
49 25525164 Exome array analysis identifies CAV1/CAV2 as a susceptibility locus for intraocular pressure. Pubmed 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
50 15184364 Protein 4.1R, a microtubule-associated protein involved in microtubule aster assembly in mammalian mitotic extract. Pubmed 1.586E-5 2.777E-3 3.044E-2
5.137E-1
 2 2
Show 45 more annotations

9: Interaction [Display Chart] 3877 annotations before applied cutoff / 16534 genes in category

No results to display

10: Cytoband [Display Chart] 187 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 3q28-q29 3q28-q29 2.113E-4 3.951E-2
2.296E-1
 3.951E-2 2 4

11: Transcription Factor Binding Site [Display Chart] 528 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$PBX1 01 V$PBX1 01 1.216E-5 6.007E-3 4.113E-2 6.419E-3 12 201
2 WTGAAAT UNKNOWN WTGAAAT UNKNOWN 2.275E-5 6.007E-3 4.113E-2 1.201E-2 19 496
3 V$CIZ 01 V$CIZ 01 1.982E-4 3.488E-2
2.389E-1
1.047E-1
 10 191
4 V$OCT1 04 V$OCT1 04 2.876E-4 3.796E-2
2.599E-1
1.518E-1
 10 200
5 V$TEF Q6 V$TEF Q6 3.642E-4 3.846E-2
2.634E-1
1.923E-1
 10 206
6 V$CDC5 01 V$CDC5 01 4.923E-4 4.333E-2
2.967E-1
2.600E-1
 10 214
Show 1 more annotation

12: Gene Family [Display Chart] 124 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1021 Ankyrin repeat domain containing|Death associated protein kinases genenames.org 6.731E-4 2.796E-2
1.510E-1
8.347E-2
 2 5
2 1324 STEAP family genenames.org 6.731E-4 2.796E-2
1.510E-1
8.347E-2
 2 5
3 542 Endogenous ligands genenames.org 8.280E-4 2.796E-2
1.510E-1
1.027E-1
 8 237
4 532 GATA zinc finger domain containing|Myb/SANT domain containing genenames.org 9.734E-4 2.796E-2
1.510E-1
1.207E-1
 4 53
5 567 Glutathione S-transferases genenames.org 1.127E-3 2.796E-2
1.510E-1
1.398E-1
 3 25
6 555 Fibronectin type III domain containing|Immunoglobulin like domain containing genenames.org 2.200E-3 4.200E-2
2.269E-1
2.727E-1
 6 160
7 169 Adrenoceptors genenames.org 2.371E-3 4.200E-2
2.269E-1
2.940E-1
 2 9
8 854 Neuropeptide receptors genenames.org 2.948E-3 4.569E-2
2.468E-1
3.655E-1
 2 10
9 286 G protein-coupled receptors, Class F frizzled genenames.org 3.583E-3 4.937E-2
2.667E-1
4.443E-1
 2 11
Show 4 more annotations

13: Coexpression [Display Chart] 6715 annotations before applied cutoff / 21867 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M15981 Genes up-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.838E-106 2.577E-102 2.420E-101 2.577E-102 94 430
2 M2255 Genes commonly up-regulated in UET-13 cells (mesenchymal progenitor) by expression of EWSR1 [GeneID=2130] fusions with ETS transcription factors FLI1 and ERG [GeneID=2313 ,2078]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.533E-54 5.146E-51 4.832E-50 1.029E-50 52 259
3 M18322 Genes up-regulated in RD-EF cells (rhabdomyosarcoma) engineered to express EWSR1-FLI1 fusion [GeneID=2130;2313] and which are also highly expressed in Ewing's famliy tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.138E-52 4.786E-49 4.494E-48 1.436E-48 37 88
4 M10582 Genes up-regulated in Ewing family tumors (EFT) compared with normal bone marrow samples. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.468E-28 2.465E-25 2.315E-24 9.861E-25 18 33
5 M1351 Genes down-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 48 h. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.253E-10 1.682E-7 1.580E-6 8.411E-7 22 428
6 M4680 Genes up-regulated in RD cells (embryonal rhabdomyosarcoma, ERMS) by expression of PAX3- or PAX7-FOXO1 [GeneID=5077;5081;2308] fusions off retroviral vectors. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.813E-9 3.149E-6 2.956E-5 1.889E-5 16 255
7 M1834 Genes up-regulated in freshly isolated CD31- [GeneID=5175] (stromal stem cells from adipose tissue) versus the CD31+ (non-stem) counterparts. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.751E-8 2.639E-5 2.478E-4 1.848E-4 15 260
8 M15694 Down-regulated genes characteristic for autonomous thyroid adenoma. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.510E-8 3.551E-5 3.334E-4 3.028E-4 8 55
9 M19432 Genes up-regulated during pubertal mammary gland development between week 4 and 5. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.759E-8 3.551E-5 3.334E-4 3.196E-4 15 271
10 M17923 Genes up-regulated in cultured stromal stem cells from adipose tissue, compared to the freshly isolated cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.255E-7 8.424E-5 7.910E-4 8.424E-4 18 425
11 M7928 Genes up-regulated in the MM1S cells (multiple myeloma) after treatment with aplidin [PubChem=44152164], a marine-derived compound with potential anti-cancer properties. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.027E-7 1.237E-4 1.162E-3 1.361E-3 18 439
12 M3030 Genes up-regulated in comparison of effector CD8 T cells at the peak expansion phase (day8) versus those at contraction (day 15) after LCMV-Armstrong infection in mice. MSigDB C7: Immunologic Signatures (v5.1) 4.364E-7 2.209E-4 2.074E-3 2.931E-3 12 199
13 M5293 Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from young donors versus those treated with TSST at 72 h. MSigDB C7: Immunologic Signatures (v5.1) 4.364E-7 2.209E-4 2.074E-3 2.931E-3 12 199
14 M5907 Genes defining late response to estrogen. MSigDB H: Hallmark Gene Sets (v5.1) 4.605E-7 2.209E-4 2.074E-3 3.092E-3 12 200
15 M6321 Genes down-regulated in spleen from DUSP1 [GeneID=1843] knockout: control versus LPS. MSigDB C7: Immunologic Signatures (v5.1) 5.901E-7 2.604E-4 2.445E-3 3.962E-3 11 168
16 M1124 Pubertal genes up-regulated by TGFB1 [GeneID=7040]. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.260E-7 2.604E-4 2.445E-3 4.204E-3 11 169
17 M8513 Genes up-regulated in the normal-like subtype of breast cancer. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.593E-7 2.604E-4 2.445E-3 4.427E-3 18 476
18 M1839 Down-regulated genes in NMuMG cells (mammary epithelium) after stimulation with TGFB1 [GeneID=7040]. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.578E-7 3.200E-4 3.005E-3 5.760E-3 9 108
19 M2781 Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of BMI1 [Gene ID=648] gene by RNAi. MSigDB C6: Oncogenic Signatures (v5.1) 1.135E-6 4.011E-4 3.766E-3 7.621E-3 10 144
20 M990 Genes down-regulated in multiple myeloma (MM) bone marrow mesenchymal stem cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.686E-6 5.661E-4 5.315E-3 1.132E-2 7 61
21 M2293 Genes down-regulated in ES (embryonic stem cells) with defficient SUZ12 [GeneID=23512]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.882E-6 6.019E-4 5.652E-3 1.264E-2 14 315
22 M1111 Down-regulated genes from the set A (Fig. 5a): specific to cells expressing MLL-AF4 [GeneID=4297;4299] fusion protein alone. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.166E-6 6.434E-4 6.041E-3 1.455E-2 8 90
23 M13273 Genes down-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.204E-6 6.434E-4 6.041E-3 1.480E-2 12 232
24 M9032 Down-regulated in MCF7 cells (breast cancer) by TLX1 (HOX11) [GeneID=3195]. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.312E-6 6.468E-4 6.073E-3 1.552E-2 11 193
25 M1804 Genes up-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [GeneID=6605] off a retroviral vector. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.744E-6 7.194E-4 6.754E-3 1.843E-2 13 280
26 M6736 Genes down-regulated in B lymphocytes versus CD8 T cells. MSigDB C7: Immunologic Signatures (v5.1) 2.821E-6 7.194E-4 6.754E-3 1.894E-2 11 197
27 M1417 Genes down-regulated during epithelial to mesenchymal transition (EMT) induced by TGFB1 [GeneID=7040] in the EpH4 cells (mammary epithelium cell line transformed by HRAS [GeneID=3265]). MSigDB C2: CGP Curated Gene Sets (v5.1) 2.892E-6 7.194E-4 6.754E-3 1.942E-2 7 66
28 M5242 Genes down-regulated in comparison of macrophages exposed to L. donovani versus macrophages exposed to M. tuberculosis. MSigDB C7: Immunologic Signatures (v5.1) 3.264E-6 7.635E-4 7.169E-3 2.192E-2 11 200
29 M19391 Genes down-regulated in prostate cancer samples. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.297E-6 7.635E-4 7.169E-3 2.214E-2 17 480
30 M2858 Genes up-regulated in NOMO-1 and SKM-1 cells (AML) after knockdown of STK33 [Gene ID=65975] by RNAi. MSigDB C6: Oncogenic Signatures (v5.1) 3.735E-6 8.361E-4 7.850E-3 2.508E-2 13 288
31 M14228 Cluster a: genes identifying an intrinsic group in head and neck squamous cell carcinoma (HNSCC). MSigDB C2: CGP Curated Gene Sets (v5.1) 4.798E-6 1.007E-3 9.454E-3 3.222E-2 8 100
32 M6920 Genes up-regulated in the nucleus accumbens (a major reward center in the brain) 8 weeks after induction of CREB1 [GeneID=1385] expression in a transgenic Tet-Off system. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.798E-6 1.007E-3 9.454E-3 3.222E-2 8 100
33 M3645 Genes up-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.054E-6 1.029E-3 9.657E-3 3.394E-2 16 443
34 M9639 Genes up-regulated in MDA-MB-231 cells (breast cancer) after knockdown of SATB1 [GeneID=6304] by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.529E-6 1.092E-3 1.025E-2 3.713E-2 15 395
35 M17471 Genes up-regulated in invasive ductal carcinoma (IDC) relative to ductal carcinoma in situ (DCIS, non-invasive). MSigDB C2: CGP Curated Gene Sets (v5.1) 6.565E-6 1.259E-3 1.183E-2 4.408E-2 14 351
36 M1600 Genes up-regulated in the nucleus accumbens (a major reward center in the brain) after 4 weeks of cocaine [PubChem=5760] treatment. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.863E-6 1.280E-3 1.202E-2 4.608E-2 7 75
37 M8519 Genes down-regulated in mARMS (molecular ARMS) compared to the mERMS (molecular ERMS) class of rhabdomyosarcoma tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.272E-6 1.639E-3 1.538E-2
6.226E-2
 10 182
38 GSE37605 FOXP3 FUSION GFP VS IRES GFP TREG C57BL6 UP Genes up-regulated in T reg (FOXP3+ [GeneID=50943]) cells from B6 mice: Foxp3-Fusion-GFP versus Foxp3-ires-GFP. MSigDB C7: Immunologic Signatures (v5.1) 9.272E-6 1.639E-3 1.538E-2
6.226E-2
 10 182
39 M3335 Genes up-regulated in at least one of three multiple myeloma (MM) cell lines by TSA [PubChem=5562]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.051E-5 1.791E-3 1.682E-2
7.057E-2
 13 317
40 M863 Myb-regulated genes in MCF7 (breast cancer) and lung epithelial cell lines overexpressing MYBL2, MYBL1 or MYB [GeneID=4605;4603;4602]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.087E-5 1.791E-3 1.682E-2
7.298E-2
 13 318
41 M2775 Genes down-regulated in DAOY cells (medulloblastoma) upon knockdown of BMI1 and PCGF2 [Gene ID=648, 7703] genes by RNAi. MSigDB C6: Oncogenic Signatures (v5.1) 1.100E-5 1.791E-3 1.682E-2
7.389E-2
 9 147
42 M19261 Genes specifically expressed in samples from patients with pediatric AML (acute myeloid leukemia ) bearing t(8;21) translocation. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.120E-5 1.791E-3 1.682E-2
7.523E-2
 14 368
43 M2681 Genes down-regulated in myometrial cells over-expressing a shortened splice form of ATF2 [Gene ID=1386] gene. MSigDB C6: Oncogenic Signatures (v5.1) 1.175E-5 1.836E-3 1.724E-2
7.893E-2
 10 187
44 M2143 Genes down-regulated in SH-SY5Y cells (neuroblastoma) after knockdown of NF1 [GeneID=4763] by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.268E-5 1.914E-3 1.797E-2
8.516E-2
 8 114
45 M9150 Genes from common genomic gains observed in a meta analyis of copy number alterations across a panel of different cancer cell lines and tumor samples. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.283E-5 1.914E-3 1.797E-2
8.612E-2
 13 323
46 M11350 Genes with GO annotation and down-regulated after DNA damage in cell lines from young donors. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.692E-5 2.432E-3 2.284E-2
1.136E-1
 10 195
47 M1544 Downregulated in the cerebellum of aged adult mice (30-month) vs young adult (5-month) MSigDB C2: CGP Curated Gene Sets (v5.1) 1.702E-5 2.432E-3 2.284E-2
1.143E-1
 7 86
48 GSE11961 FOLLICULAR BCELL VS MARGINAL ZONE BCELL DN Genes down-regulated in follicular B cells versus marginal zone B cells. MSigDB C7: Immunologic Signatures (v5.1) 2.016E-5 2.563E-3 2.406E-2
1.354E-1
 10 199
49 M4606 Genes down-regulated in comparison of CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 7 versus CD25- T cells treated with IL4 [GeneID=3565] at day 7. MSigDB C7: Immunologic Signatures (v5.1) 2.016E-5 2.563E-3 2.406E-2
1.354E-1
 10 199
50 M5295 Genes up-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from old donors versus those treated with TSST at 16 h. MSigDB C7: Immunologic Signatures (v5.1) 2.016E-5 2.563E-3 2.406E-2
1.354E-1
 10 199
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 3609 annotations before applied cutoff / 20974 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 54Dn SubClass 54Dn 1SK Top 500 All 54Dn SubClass 54Dn 1SK Top 500 All Brain Map - Allen iN 9.926E-14 3.582E-10 3.141E-9 3.582E-10 27 461
2 GSM777050 500 Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5 Immgen.org, GSE15907 9.414E-13 1.699E-9 1.490E-8 3.398E-9 26 467
3 GSM777046 500 Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4 Immgen.org, GSE15907 1.543E-12 1.856E-9 1.628E-8 5.569E-9 25 438
4 gudmap dev gonad e11.5 M GonMes Sma 500 dev gonad e11.5 M GonMes Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 8.256E-12 7.449E-9 6.531E-8 2.979E-8 24 433
5 GSM777055 500 Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4 Immgen.org, GSE15907 2.324E-11 1.677E-8 1.471E-7 8.386E-8 24 455
6 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 k2 500 dev lower uro neuro e15.5 PelvicGanglion Sox10 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 2.916E-11 1.754E-8 1.538E-7 1.052E-7 14 127
7 gudmap developingLowerUrinaryTract e14.5 Genital tubercle 500 DevelopingLowerUrinaryTract e14.5 Genital tubercle emap-6706 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 4.839E-11 2.495E-8 2.188E-7 1.747E-7 22 391
8 GSM777059 500 Stromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 7.129E-11 3.216E-8 2.820E-7 2.573E-7 23 439
9 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 500 dev lower uro neuro e15.5 PelvicGanglion Sox10 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.286E-10 4.354E-8 3.818E-7 4.640E-7 21 372
10 neurons SubClass glutamin-Med Top 500 All neurons SubClass glutamin-Med Top 500 All Brain Map - Barres 1.315E-10 4.354E-8 3.818E-7 4.746E-7 24 495
11 GSM777067 500 Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2 Immgen.org, GSE15907 1.327E-10 4.354E-8 3.818E-7 4.789E-7 23 453
12 gudmap dev gonad e11.5 M GonadVasMes Flk 500 dev gonad e11.5 M GonadVasMes Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.819E-10 5.470E-8 4.796E-7 6.563E-7 22 419
13 gudmap dev gonad e11.5 F GonadVasMes Flk 500 dev gonad e11.5 F GonadVasMes Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 2.278E-10 6.323E-8 5.544E-7 8.220E-7 22 424
14 gudmap dev gonad e11.5 F GonadVasMes Flk k3 1000 dev gonad e11.5 F GonadVasMes Flk k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 3.760E-10 9.693E-8 8.499E-7 1.357E-6 20 355
15 gudmap dev gonad e11.5 F GonMes Sma 500 dev gonad e11.5 F GonMes Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 4.029E-10 9.693E-8 8.499E-7 1.454E-6 22 437
16 gudmap developingLowerUrinaryTract e14.5 Genital tubercle 200 DevelopingLowerUrinaryTract e14.5 Genital tubercle emap-6706 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 5.526E-10 1.246E-7 1.093E-6 1.994E-6 14 158
17 gudmap dev gonad e11.5 F GonMes Sma k4 1000 dev gonad e11.5 F GonMes Sma k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 6.646E-10 1.411E-7 1.237E-6 2.399E-6 19 328
18 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 k4 1000 dev lower uro neuro e15.5 PelvicGanglion Sox10 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 9.282E-10 1.861E-7 1.632E-6 3.350E-6 17 261
19 gudmap dev gonad e11.5 M GonadVasMes Flk k1 1000 dev gonad e11.5 M GonadVasMes Flk k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 1.097E-9 2.083E-7 1.827E-6 3.958E-6 19 338
20 54Dn SubClass 54Dn 1SK Top 500 Cluster 2 54Dn SubClass 54Dn 1SK Top 500 Cluster 2 Brain Map - Allen iN 1.171E-9 2.092E-7 1.834E-6 4.226E-6 17 265
21 gudmap developingKidney e15.5 Peripheral blastema 500 DevelopingKidney e15.5 Peripheral blastema emap-27731 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.217E-9 2.092E-7 1.834E-6 4.393E-6 21 421
22 gudmap developingKidney e15.5 Pelvic Mesenchyme 1000 k2 DevelopingKidney e15.5 Pelvic Mesenchyme emap-8241 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.421E-9 2.331E-7 2.044E-6 5.127E-6 18 305
23 gudmap dev gonad e11.5 M GonMes Sma k3 1000 dev gonad e11.5 M GonMes Sma k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 2.036E-9 3.196E-7 2.802E-6 7.350E-6 18 312
24 54Dn Top 500 All 54Dn Top 500 All Brain Map - Allen iN 3.771E-9 5.650E-7 4.954E-6 1.361E-5 22 493
25 80Dn Top 500 All 80Dn Top 500 All Brain Map - Allen iN 3.914E-9 5.650E-7 4.954E-6 1.412E-5 22 494
26 gudmap dev gonad e13.5 F VascAssocMesenchStromOvary Sma 500 dev gonad e13.5 F VascAssocMesenchStromOvary Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 5.549E-9 7.702E-7 6.754E-6 2.003E-5 19 373
27 gudmap kidney adult RenMedVasc Tie2 500 kidney adult RenMedVasc Tie2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 6.007E-9 8.029E-7 7.040E-6 2.168E-5 20 417
28 DevelopingLowerUrinaryTract e14.5 bladder emap-6668 500 DevelopingLowerUrinaryTract e14.5 bladder emap-6668 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 7.345E-9 9.467E-7 8.301E-6 2.651E-5 20 422
29 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 500 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 8.955E-9 1.114E-6 9.772E-6 3.232E-5 20 427
30 gudmap developingLowerUrinaryTract e14.5 urethra 1000 k3 DevelopingLowerUrinaryTract e14.5 urethra emap-30892 k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.923E-8 2.313E-6 2.028E-5 6.939E-5 15 243
31 GSM777063 500 Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 2.149E-8 2.502E-6 2.194E-5 7.757E-5 20 450
32 gudmap developingLowerUrinaryTract e14.5 urethra 500 DevelopingLowerUrinaryTract e14.5 urethra emap-30892 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 2.353E-8 2.653E-6 2.326E-5 8.490E-5 19 408
33 gudmap dev gonad e13.5 M InterstitTestis Sma 200 dev gonad e13.5 M InterstitTestis Sma top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 2.650E-8 2.898E-6 2.542E-5 9.565E-5 12 148
34 gudmap dev gonad e12.5 M InterstitTestis Sma 500 dev gonad e12.5 M InterstitTestis Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 3.398E-8 3.607E-6 3.163E-5 1.226E-4 18 374
35 gudmap developingLowerUrinaryTract e13.5 bladder mesenchyme 500 DevelopingLowerUrinaryTract e13.5 bladder mesenchyme emap-3087 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.870E-8 3.990E-6 3.499E-5 1.397E-4 19 421
36 gudmap developingLowerUrinaryTract e13.5 bladder neck-urethr mesench 500 DevelopingLowerUrinaryTract e13.5 bladder neck-urethr mesench emap-3087 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 4.329E-8 4.340E-6 3.805E-5 1.562E-4 19 424
37 gudmap dev gonad e12.5 F VasAssocMesStromOvary Sma 500 dev gonad e12.5 F VasAssocMesStromOvary Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 5.483E-8 5.348E-6 4.690E-5 1.979E-4 18 386
38 gudmap developingKidney e15.5 Ureteral Smooth Musc 1000 k4 DevelopingKidney e15.5 Ureteral Smooth Musc emap-28812 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 7.116E-8 6.759E-6 5.926E-5 2.568E-4 13 195
39 gudmap developingKidney e15.5 Ureteral Smooth Musc 1000 k2 DevelopingKidney e15.5 Ureteral Smooth Musc emap-28812 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 7.745E-8 7.167E-6 6.284E-5 2.795E-4 15 270
40 neurons SubClass CRH-med Top 500 All neurons SubClass CRH-med Top 500 All Brain Map - Barres 8.970E-8 8.093E-6 7.096E-5 3.237E-4 20 491
41 gudmap dev gonad e11.5 M ReproVasc Flk k2 500 dev gonad e11.5 M ReproVasc Flk k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 9.509E-8 8.370E-6 7.339E-5 3.432E-4 8 58
42 gudmap dev gonad e13.5 F VascAssocMesenchStromOvary MafB 500 dev gonad e13.5 F VascAssocMesenchStromOvary MafB top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.006E-7 8.643E-6 7.578E-5 3.630E-4 17 358
43 endothelial Top 500 All endothelial Top 500 All Brain Map - Barres 1.057E-7 8.868E-6 7.776E-5 3.813E-4 20 496
44 gudmap dev gonad e13.5 M InterstitTestis Sma 500 dev gonad e13.5 M InterstitTestis Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.179E-7 9.670E-6 8.479E-5 4.255E-4 17 362
45 GSM476663 500 Stem Cells, SC.LTSL.BM, CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-1 Immgen.org, GSE15907 1.305E-7 1.024E-5 8.979E-5 4.710E-4 18 409
46 gudmap dev gonad e11.5 F ReproVasc Flk 500 dev gonad e11.5 F ReproVasc Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.305E-7 1.024E-5 8.979E-5 4.710E-4 18 409
47 gudmap kidney adult RenalCapsule 500 kidney adult RenalCapsule top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.353E-7 1.039E-5 9.112E-5 4.884E-4 18 410
48 GSM777037 500 Stromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 1.493E-7 1.123E-5 9.845E-5 5.389E-4 19 459
49 gudmap dev gonad e11.5 M ReproVasc Flk 500 dev gonad e11.5 M ReproVasc Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.563E-7 1.151E-5 1.010E-4 5.641E-4 18 414
50 54Dn SubClass 54Dn 1SK Top 500 Cluster 0 54Dn SubClass 54Dn 1SK Top 500 Cluster 0 Brain Map - Allen iN 1.622E-7 1.171E-5 1.026E-4 5.853E-4 8 62
Show 45 more annotations

15: Computational [Display Chart] 412 annotations before applied cutoff / 9399 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 module 1 Genes in module 1 MSigDb: C4 - CM: Cancer Modules 3.112E-7 1.282E-4 8.461E-4 1.282E-4 20 361
2 module 2 Genes in module 2 MSigDb: C4 - CM: Cancer Modules 6.478E-7 1.335E-4 8.807E-4 2.669E-4 20 378
3 module 5 Genes in module 5 MSigDb: C4 - CM: Cancer Modules 1.381E-5 1.897E-3 1.252E-2 5.691E-3 19 423
4 module 154 Genes in module 154 MSigDb: C4 - CM: Cancer Modules 1.048E-4 8.922E-3
5.888E-2
 4.317E-2 7 74
5 module 52 Genes in module 52 MSigDb: C4 - CM: Cancer Modules 1.429E-4 8.922E-3
5.888E-2
5.888E-2
 17 419
6 module 357 Genes in module 357 MSigDb: C4 - CM: Cancer Modules 1.588E-4 8.922E-3
5.888E-2
6.541E-2
 7 79
7 module 297 Genes in module 297 MSigDb: C4 - CM: Cancer Modules 1.588E-4 8.922E-3
5.888E-2
6.541E-2
 7 79
8 module 19 Genes in module 19 MSigDb: C4 - CM: Cancer Modules 1.732E-4 8.922E-3
5.888E-2
7.137E-2
 14 307
9 module 12 Genes in module 12 MSigDb: C4 - CM: Cancer Modules 2.059E-4 9.423E-3
6.219E-2
8.481E-2
 15 351
10 module 118 Genes in module 118 MSigDb: C4 - CM: Cancer Modules 2.313E-4 9.528E-3
6.288E-2
9.528E-2
 16 395
11 module 6 Genes in module 6 MSigDb: C4 - CM: Cancer Modules 3.238E-4 1.175E-2
7.756E-2
1.334E-1
 16 407
12 module 220 Genes in module 220 MSigDb: C4 - CM: Cancer Modules 3.423E-4 1.175E-2
7.756E-2
1.410E-1
 14 328
13 module 128 Genes in module 128 MSigDb: C4 - CM: Cancer Modules 6.004E-4 1.833E-2
1.210E-1
2.473E-1
 7 98
14 module 79 Genes in module 79 MSigDb: C4 - CM: Cancer Modules 6.779E-4 1.833E-2
1.210E-1
2.793E-1
 7 100
15 module 170 Genes in module 170 MSigDb: C4 - CM: Cancer Modules 6.779E-4 1.833E-2
1.210E-1
2.793E-1
 7 100
16 module 382 Genes in module 382 MSigDb: C4 - CM: Cancer Modules 7.118E-4 1.833E-2
1.210E-1
2.933E-1
 4 28
17 module 129 Genes in module 129 MSigDb: C4 - CM: Cancer Modules 1.393E-3 3.366E-2
2.221E-1
5.739E-1
 10 217
18 module 37 Genes in module 37 MSigDb: C4 - CM: Cancer Modules 1.470E-3 3.366E-2
2.221E-1
6.058E-1
 15 424
19 module 334 Genes in module 334 MSigDb: C4 - CM: Cancer Modules 1.761E-3 3.818E-2
2.519E-1
7.253E-1
 8 151
20 module 208 Genes in module 208 MSigDb: C4 - CM: Cancer Modules 1.973E-3 4.065E-2
2.683E-1
8.131E-1
 7 120
Show 15 more annotations

16: MicroRNA [Display Chart] 1399 annotations before applied cutoff / 19844 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-624:PITA hsa-miR-624:PITA TOP PITA 4.907E-9 6.865E-6 5.369E-5 6.865E-6 17 276
2 hsa-miR-452:PITA hsa-miR-452:PITA TOP PITA 1.073E-8 7.504E-6 5.869E-5 1.501E-5 21 451
3 miR-203:PicTar miR-203:PicTar PicTar 6.815E-8 3.178E-5 2.485E-4 9.534E-5 17 330
4 hsa-miR-499-3p:PITA hsa-miR-499-3p:PITA TOP PITA 1.290E-7 4.511E-5 3.528E-4 1.804E-4 17 345
5 hsa-miR-101:PITA hsa-miR-101:PITA TOP PITA 6.567E-7 1.837E-4 1.437E-3 9.187E-4 19 479
6 hsa-miR-135b:PITA hsa-miR-135b:PITA TOP PITA 1.126E-6 1.936E-4 1.514E-3 1.576E-3 18 449
7 hsa-miR-135a:PITA hsa-miR-135a:PITA TOP PITA 1.126E-6 1.936E-4 1.514E-3 1.576E-3 18 449
8 hsa-miR-543:TargetScan hsa-miR-543:TargetScan TargetScan 1.139E-6 1.936E-4 1.514E-3 1.593E-3 19 497
9 miR-181c:PicTar miR-181c:PicTar PicTar 1.245E-6 1.936E-4 1.514E-3 1.742E-3 19 500
10 hsa-miR-505:PITA hsa-miR-505:PITA TOP PITA 1.568E-6 2.194E-4 1.716E-3 2.194E-3 13 242
11 miR-199a-star:PicTar miR-199a-star:PicTar PicTar 2.119E-6 2.695E-4 2.108E-3 2.964E-3 17 422
12 hsa-miR-578:PITA hsa-miR-578:PITA TOP PITA 2.569E-6 2.867E-4 2.242E-3 3.594E-3 15 337
13 hsa-miR-216b:PITA hsa-miR-216b:PITA TOP PITA 2.664E-6 2.867E-4 2.242E-3 3.727E-3 15 338
14 hsa-miR-548m:PITA hsa-miR-548m:PITA TOP PITA 6.126E-6 6.122E-4 4.788E-3 8.570E-3 17 457
15 hsa-miR-1253:PITA hsa-miR-1253:PITA TOP PITA 6.632E-6 6.186E-4 4.838E-3 9.278E-3 13 276
16 hsa-miR-193b:mirSVR highEffct hsa-miR-193b:mirSVR conserved highEffect-0.5 MicroRNA.org 8.880E-6 7.764E-4 6.072E-3 1.242E-2 16 421
17 hsa-miR-32:PITA hsa-miR-32:PITA TOP PITA 1.162E-5 8.164E-4 6.385E-3 1.626E-2 17 480
18 miR-335:PicTar miR-335:PicTar PicTar 1.262E-5 8.164E-4 6.385E-3 1.765E-2 9 136
19 hsa-miR-579:PITA hsa-miR-579:PITA TOP PITA 1.332E-5 8.164E-4 6.385E-3 1.864E-2 16 435
20 hsa-miR-363:PITA hsa-miR-363:PITA TOP PITA 1.364E-5 8.164E-4 6.385E-3 1.908E-2 17 486
21 hsa-miR-25:PITA hsa-miR-25:PITA TOP PITA 1.401E-5 8.164E-4 6.385E-3 1.959E-2 17 487
22 hsa-miR-92a:PITA hsa-miR-92a:PITA TOP PITA 1.401E-5 8.164E-4 6.385E-3 1.959E-2 17 487
23 hsa-miR-367:PITA hsa-miR-367:PITA TOP PITA 1.401E-5 8.164E-4 6.385E-3 1.959E-2 17 487
24 hsa-miR-92b:PITA hsa-miR-92b:PITA TOP PITA 1.401E-5 8.164E-4 6.385E-3 1.959E-2 17 487
25 hsa-miR-641:PITA hsa-miR-641:PITA TOP PITA 1.515E-5 8.480E-4 6.633E-3 2.120E-2 17 490
26 hsa-miR-155:PITA hsa-miR-155:PITA TOP PITA 1.857E-5 9.990E-4 7.813E-3 2.597E-2 13 304
27 hsa-miR-653:PITA hsa-miR-653:PITA TOP PITA 1.989E-5 1.031E-3 8.060E-3 2.783E-2 13 306
28 CATTTCA,MIR-203:MSigDB CATTTCA,MIR-203:MSigDB MSigDB 2.149E-5 1.074E-3 8.398E-3 3.007E-2 12 264
29 hsa-miR-1277:mirSVR lowEffct hsa-miR-1277:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 2.500E-5 1.197E-3 9.362E-3 3.497E-2 16 458
30 hsa-miR-377:PITA hsa-miR-377:PITA TOP PITA 2.567E-5 1.197E-3 9.362E-3 3.591E-2 16 459
31 hsa-miR-216a:PITA hsa-miR-216a:PITA TOP PITA 2.787E-5 1.220E-3 9.542E-3 3.899E-2 14 363
32 AAAGACA,MIR-511:MSigDB AAAGACA,MIR-511:MSigDB MSigDB 3.069E-5 1.220E-3 9.542E-3 4.294E-2 10 190
33 hsa-miR-147:PITA hsa-miR-147:PITA TOP PITA 3.398E-5 1.220E-3 9.542E-3 4.753E-2 9 154
34 hsa-miR-193a-3p:mirSVR highEffct hsa-miR-193a-3p:mirSVR conserved highEffect-0.5 MicroRNA.org 3.414E-5 1.220E-3 9.542E-3 4.776E-2 16 470
35 hsa-let-7g:PITA hsa-let-7g:PITA TOP PITA 3.750E-5 1.220E-3 9.542E-3
5.246E-2
 14 373
36 hsa-let-7e:PITA hsa-let-7e:PITA TOP PITA 3.750E-5 1.220E-3 9.542E-3
5.246E-2
 14 373
37 hsa-let-7c:PITA hsa-let-7c:PITA TOP PITA 3.750E-5 1.220E-3 9.542E-3
5.246E-2
 14 373
38 hsa-let-7b:PITA hsa-let-7b:PITA TOP PITA 3.750E-5 1.220E-3 9.542E-3
5.246E-2
 14 373
39 hsa-let-7f:PITA hsa-let-7f:PITA TOP PITA 3.750E-5 1.220E-3 9.542E-3
5.246E-2
 14 373
40 hsa-let-7a:PITA hsa-let-7a:PITA TOP PITA 3.750E-5 1.220E-3 9.542E-3
5.246E-2
 14 373
41 hsa-let-7d:PITA hsa-let-7d:PITA TOP PITA 3.750E-5 1.220E-3 9.542E-3
5.246E-2
 14 373
42 hsa-let-7i:PITA hsa-let-7i:PITA TOP PITA 3.750E-5 1.220E-3 9.542E-3
5.246E-2
 14 373
43 hsa-miR-98:PITA hsa-miR-98:PITA TOP PITA 3.750E-5 1.220E-3 9.542E-3
5.246E-2
 14 373
44 hsa-miR-155:TargetScan hsa-miR-155:TargetScan TargetScan 3.959E-5 1.259E-3 9.845E-3
5.539E-2
 12 281
45 hsa-miR-105:PITA hsa-miR-105:PITA TOP PITA 4.953E-5 1.540E-3 1.204E-2
6.929E-2
 15 433
46 hsa-miR-487a:PITA hsa-miR-487a:PITA TOP PITA 5.311E-5 1.615E-3 1.263E-2
7.430E-2
 11 245
47 hsa-miR-448:PITA hsa-miR-448:PITA TOP PITA 5.638E-5 1.678E-3 1.313E-2
7.888E-2
 15 438
48 hsa-miR-342-3p:PITA hsa-miR-342-3p:PITA TOP PITA 6.395E-5 1.864E-3 1.458E-2
8.947E-2
 9 167
49 hsa-miR-1264:PITA hsa-miR-1264:PITA TOP PITA 8.221E-5 2.347E-3 1.836E-2
1.150E-1
 15 453
50 hsa-miR-421:PITA hsa-miR-421:PITA TOP PITA 9.128E-5 2.554E-3 1.997E-2
1.277E-1
 13 355
Show 45 more annotations

17: Drug [Display Chart] 23585 annotations before applied cutoff / 22098 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000004599 Orlistat, 5 Stitch 7.616E-9 1.796E-4 1.912E-3 1.796E-4 10 86
2 7084 UP MS-275; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 1.837E-8 2.166E-4 2.306E-3 4.332E-4 13 183
3 667 UP 6-mercaptopurine monohydrate; Up 200; 10uM; PC3; HG-U133A Broad Institute CMAP 4.153E-8 2.731E-4 2.907E-3 9.795E-4 13 196
4 D004137 Dinitrochlorobenzene CTD 5.646E-8 2.731E-4 2.907E-3 1.332E-3 17 362
5 1234 UP Trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 5.789E-8 2.731E-4 2.907E-3 1.365E-3 12 167
6 C113580 U 0126 CTD 9.676E-8 3.803E-4 4.049E-3 2.282E-3 18 422
7 CID003054237 EF-T Stitch 1.339E-7 4.388E-4 4.671E-3 3.159E-3 7 43
8 6316 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 1.488E-7 4.388E-4 4.671E-3 3.510E-3 12 182
9 3283 UP Digoxin [20830-75-5]; Up 200; 5.2uM; MCF7; HT HG-U133A Broad Institute CMAP 4.727E-7 1.239E-3 1.319E-2 1.115E-2 11 166
10 6047 UP Helveticoside [630-64-8]; Up 200; 7.4uM; MCF7; HT HG-U133A Broad Institute CMAP 5.328E-7 1.257E-3 1.338E-2 1.257E-2 11 168
11 CID005311021 BIBO3304 Stitch 7.012E-7 1.485E-3 1.581E-2 1.654E-2 5 19
12 7179 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT HG-U133A Broad Institute CMAP 7.554E-7 1.485E-3 1.581E-2 1.782E-2 11 174
13 D017258 Medroxyprogesterone Acetate CTD 8.563E-7 1.554E-3 1.654E-2 2.020E-2 16 390
14 CID000003816 NSC759587 Stitch 9.994E-7 1.684E-3 1.792E-2 2.357E-2 17 444
15 D010656 Phenylephrine CTD 1.149E-6 1.807E-3 1.924E-2 2.711E-2 18 500
16 7074 UP MS-275; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 1.311E-6 1.933E-3 2.058E-2 3.093E-2 11 184
17 C008493 methylselenic acid CTD 1.495E-6 2.074E-3 2.208E-2 3.526E-2 16 407
18 D012110 Reserpine CTD 1.782E-6 2.335E-3 2.485E-2 4.202E-2 9 119
19 D005473 Fluoxetine CTD 2.318E-6 2.867E-3 3.053E-2
5.467E-2
 14 324
20 D015544 Inositol 1,4,5-Trisphosphate CTD 2.468E-6 2.867E-3 3.053E-2
5.820E-2
 5 24
21 3617 UP Bromopride [4093-35-0]; Up 200; 11.6uM; MCF7; HT HG-U133A Broad Institute CMAP 2.553E-6 2.867E-3 3.053E-2
6.022E-2
 11 197
22 D009638 Norepinephrine CTD 3.548E-6 3.452E-3 3.675E-2
8.369E-2
 10 165
23 3275 UP Digitoxigenin [143-62-4]; Up 200; 10.6uM; MCF7; HT HG-U133A Broad Institute CMAP 3.548E-6 3.452E-3 3.675E-2
8.369E-2
 10 165
24 CID000123797 Neuropeptide Ff Stitch 3.654E-6 3.452E-3 3.675E-2
8.618E-2
 7 69
25 MESH:D011471/D005472-T Prostatic Neoplasms affected by Fluorouracil CTD Therapeutic 3.820E-6 3.452E-3 3.675E-2
9.009E-2
 8 98
26 D014302 Trinitrobenzenesulfonic Acid CTD 3.932E-6 3.452E-3 3.675E-2
9.273E-2
 15 388
27 5640 UP Digoxigenin [1672-46-4]; Up 200; 10.2uM; MCF7; HT HG-U133A Broad Institute CMAP 3.952E-6 3.452E-3 3.675E-2
9.321E-2
 10 167
28 1132 UP BW-B 70C; Up 200; 31.6uM; MCF7; HT HG-U133A EA Broad Institute CMAP 4.395E-6 3.575E-3 3.805E-2
1.037E-1
 10 169
29 CID000005641 urethane Stitch 4.395E-6 3.575E-3 3.805E-2
1.037E-1
 10 169
30 2423 UP Digoxin [20830-75-5]; Up 200; 5.2uM; HL60; HT HG-U133A Broad Institute CMAP 4.632E-6 3.642E-3 3.877E-2
1.093E-1
 10 170
31 4458 UP Trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 4.881E-6 3.713E-3 3.953E-2
1.151E-1
 10 171
32 2007 UP Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; HL60; HG-U133A Broad Institute CMAP 5.412E-6 3.989E-3 4.246E-2
1.276E-1
 10 173
33 2084 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 5.696E-6 4.071E-3 4.334E-2
1.343E-1
 10 174
34 MESH:D011471/C006632-T Prostatic Neoplasms affected by arsenic trioxide CTD Therapeutic 6.063E-6 4.117E-3 4.383E-2
1.430E-1
 9 138
35 CID000005707 xylazine Stitch 6.110E-6 4.117E-3 4.383E-2
1.441E-1
 6 49
36 3993 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 6.627E-6 4.157E-3 4.425E-2
1.563E-1
 10 177
37 CID000003804 Prestwick 517 Stitch 6.869E-6 4.157E-3 4.425E-2
1.620E-1
 8 106
38 5940 UP trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 6.965E-6 4.157E-3 4.425E-2
1.643E-1
 10 178
39 CID000027525 Cloralosa Stitch 7.007E-6 4.157E-3 4.425E-2
1.653E-1
 7 76
40 D000079 Acetaldehyde CTD 7.050E-6 4.157E-3 4.425E-2
1.663E-1
 11 219
41 6340 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 7.686E-6 4.230E-3 4.503E-2
1.813E-1
 10 180
42 7236 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT HG-U133A Broad Institute CMAP 7.686E-6 4.230E-3 4.503E-2
1.813E-1
 10 180
43 4662 UP Menadione [58-27-5]; Up 200; 23.2uM; PC3; HT HG-U133A Broad Institute CMAP 8.070E-6 4.230E-3 4.503E-2
1.903E-1
 10 181
44 6276 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT HG-U133A Broad Institute CMAP 8.070E-6 4.230E-3 4.503E-2
1.903E-1
 10 181
45 5822 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 8.070E-6 4.230E-3 4.503E-2
1.903E-1
 10 181
46 6671 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 1.025E-5 5.256E-3
5.595E-2
2.418E-1
 10 186
47 D000841 Anisomycin CTD 1.072E-5 5.279E-3
5.619E-2
2.527E-1
 7 81
48 6709 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 1.074E-5 5.279E-3
5.619E-2
2.534E-1
 10 187
49 CID000000827 D-arabinitol Stitch 1.176E-5 5.662E-3
6.028E-2
2.774E-1
 8 114
50 952 UP carbamazepine; Up 200; 0.1uM; MCF7; HT HG-U133A EA Broad Institute CMAP 1.234E-5 5.823E-3
6.199E-2
2.911E-1
 10 190
Show 45 more annotations

18: Disease [Display Chart] 2544 annotations before applied cutoff / 16150 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 umls:C0553580 Ewings sarcoma DisGeNET Curated 8.570E-13 2.180E-9 1.835E-8 2.180E-9 20 215
2 umls:C0023269 leiomyosarcoma DisGeNET Curated 9.478E-6 1.014E-2
8.540E-2
 2.411E-2 9 117
3 umls:C0281899 Prolapsed lumbar disc DisGeNET BeFree 1.196E-5 1.014E-2
8.540E-2
 3.043E-2 4 13
4 umls:C0236663 Alcohol withdrawal syndrome DisGeNET BeFree 2.763E-5 1.450E-2
1.221E-1
7.028E-2
 5 31
5 umls:C0454455 Mirror movements disorder DisGeNET BeFree 3.074E-5 1.450E-2
1.221E-1
7.821E-2
 3 6
6 umls:C0023267 Fibroid Tumor DisGeNET Curated 3.420E-5 1.450E-2
1.221E-1
8.700E-2
 13 287
7 umls:C1959632 Plasma Cell Neoplasm DisGeNET BeFree 4.890E-5 1.474E-2
1.241E-1
1.244E-1
 4 18
8 umls:C3536893 Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor DisGeNET BeFree 5.082E-5 1.474E-2
1.241E-1
1.293E-1
 5 35
9 umls:C0011884 Diabetic Retinopathy DisGeNET Curated 5.443E-5 1.474E-2
1.241E-1
1.385E-1
 10 181
10 umls:C0206093 Neuroectodermal Tumors DisGeNET Curated 5.793E-5 1.474E-2
1.241E-1
1.474E-1
 6 58
11 umls:C0038356 Stomach Neoplasms DisGeNET Curated 6.514E-5 1.507E-2
1.268E-1
1.657E-1
 17 490
12 umls:C0206651 Sarcoma, Clear Cell DisGeNET Curated 7.637E-5 1.619E-2
1.363E-1
1.943E-1
 5 38
13 umls:C0032000 Pituitary Adenoma DisGeNET BeFree 9.484E-5 1.803E-2
1.518E-1
2.413E-1
 12 274
14 umls:C0206663 Neuroectodermal Tumor, Primitive DisGeNET Curated 9.923E-5 1.803E-2
1.518E-1
2.524E-1
 8 123
15 umls:C0042133 Uterine Fibroids DisGeNET Curated 1.173E-4 1.824E-2
1.536E-1
2.984E-1
 13 324
16 umls:C0017525 Giant Cell Tumors DisGeNET BeFree 1.204E-4 1.824E-2
1.536E-1
3.062E-1
 6 66
17 umls:C0278701 Gastric Adenocarcinoma DisGeNET BeFree 1.286E-4 1.824E-2
1.536E-1
3.272E-1
 12 283
18 umls:C1861367 Synpolydactyly 1 DisGeNET Curated 1.362E-4 1.824E-2
1.536E-1
3.466E-1
 2 2
19 umls:C0036413 Scleredema Adultorum DisGeNET BeFree 1.362E-4 1.824E-2
1.536E-1
3.466E-1
 2 2
20 umls:C0025286 Meningioma DisGeNET Curated 1.709E-4 2.060E-2
1.735E-1
4.347E-1
 14 383
21 umls:C0399526 Class III malocclusion DisGeNET BeFree 1.782E-4 2.060E-2
1.735E-1
4.533E-1
 3 10
22 umls:C0016048 Fibromatosis DisGeNET BeFree 1.782E-4 2.060E-2
1.735E-1
4.533E-1
 3 10
23 umls:C0206728 Plexiform Neurofibroma DisGeNET Curated 1.896E-4 2.097E-2
1.766E-1
4.823E-1
 4 25
24 umls:C3665593 Melanocytic nevus of skin DisGeNET BeFree 2.143E-4 2.272E-2
1.913E-1
5.453E-1
 5 47
25 umls:C0279751 Adenoid cystic carcinoma of salivary gland DisGeNET BeFree 2.429E-4 2.472E-2
2.081E-1
6.179E-1
 3 11
26 umls:C0014474 Ependymoma DisGeNET Curated 2.772E-4 2.712E-2
2.283E-1
7.051E-1
 7 108
27 umls:C0376634 Craniofacial Abnormalities DisGeNET Curated 3.207E-4 2.982E-2
2.511E-1
8.158E-1
 9 184
28 umls:C0035412 Rhabdomyosarcoma DisGeNET Curated 3.282E-4 2.982E-2
2.511E-1
8.350E-1
 13 360
29 umls:C0013720 Ehlers-Danlos Syndrome DisGeNET Curated 3.464E-4 2.983E-2
2.511E-1
8.813E-1
 5 52
30 umls:C1709246 Non-Neoplastic Disorder DisGeNET BeFree 3.517E-4 2.983E-2
2.511E-1
8.948E-1
 15 461
31 umls:C0085074 Granuloma Annulare DisGeNET BeFree 4.056E-4 3.170E-2
2.669E-1
1.000E0
 2 3
32 umls:C0206628 Mesoblastic Nephroma DisGeNET BeFree 4.056E-4 3.170E-2
2.669E-1
1.000E0
 2 3
33 umls:C1334634 Mature B-Cell Non-Hodgkin Lymphoma DisGeNET BeFree 4.138E-4 3.170E-2
2.669E-1
1.000E0
 3 13
34 umls:C0149721 Left Ventricular Hypertrophy DisGeNET Curated 4.236E-4 3.170E-2
2.669E-1
1.000E0
 8 152
35 umls:C0033375 Prolactinoma DisGeNET Curated 4.526E-4 3.228E-2
2.718E-1
1.000E0
 6 84
36 umls:C0206754 Neuroendocrine Tumors DisGeNET Curated 4.568E-4 3.228E-2
2.718E-1
1.000E0
 10 235
37 umls:C0085762 Alcohol abuse DisGeNET BeFree 4.903E-4 3.371E-2
2.838E-1
1.000E0
 5 56
38 umls:C0409959 Osteoarthritis, Knee DisGeNET Curated 5.135E-4 3.425E-2
2.884E-1
1.000E0
 6 86
39 umls:C0349566 Squamous cell carcinoma of tongue DisGeNET BeFree 5.258E-4 3.425E-2
2.884E-1
1.000E0
 7 120
40 umls:C0338106 Adenocarcinoma of colon DisGeNET Curated 5.385E-4 3.425E-2
2.884E-1
1.000E0
 10 240
41 umls:C0242339 Dyslipidemias DisGeNET Curated 5.885E-4 3.651E-2
3.074E-1
1.000E0
 9 200
42 umls:C0432412 Chromosome 8, trisomy DisGeNET BeFree 6.247E-4 3.784E-2
3.186E-1
1.000E0
 5 59
43 umls:C0011644 Scleroderma DisGeNET BeFree 7.585E-4 4.451E-2
3.747E-1
1.000E0
 8 166
44 umls:C0001957 Alcohol Withdrawal Delirium DisGeNET BeFree 7.896E-4 4.451E-2
3.747E-1
1.000E0
 3 16
45 umls:C0155111 Bullous keratopathy DisGeNET BeFree 8.049E-4 4.451E-2
3.747E-1
1.000E0
 2 4
46 umls:C1858673 GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 2 DisGeNET Curated 8.049E-4 4.451E-2
3.747E-1
1.000E0
 2 4
47 umls:C0162810 Cicatrix, Hypertrophic DisGeNET BeFree 8.446E-4 4.572E-2
3.849E-1
1.000E0
 5 63
48 umls:C0030319 Panic Disorder DisGeNET Curated 9.196E-4 4.874E-2
4.103E-1
1.000E0
 6 96
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