|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
M2239
|
Genes down-regulated upon overexpression of PARVB [GeneID=29780] in MDA-MB-231 cells (breast cancer) cultured in 3D collagen I and 3D Matrigel only.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
3.831E-17
|
2.603E-13
|
2.447E-12
|
2.603E-13
|
30
|
334
|
2
|
GSE19888 ADENOSINE A3R INH PRETREAT AND ACT BY A3R VS A3R INH AND TCELL MEMBRANES ACT MAST CELL UP
|
Genes up-regulated in HMC-1 (mast leukemia) cells incubated with the peptide ALL1 followed by treatment with: Cl-IB-MECA [PubChem=3035850] versus T cell membranes.
|
MSigDB C7: Immunologic Signatures (v5.1)
|
4.588E-9
|
1.163E-5
|
1.093E-4
|
3.116E-5
|
16
|
197
|
3
|
M2521
|
Loci bound by both isoforms (a and b) of SALL4 [GeneID=57167] in ES cells (embryonic stem).
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
5.136E-9
|
1.163E-5
|
1.093E-4
|
3.489E-5
|
17
|
227
|
4
|
M8880
|
Genes down-regulated during pubertal mammary gland development between week 5 and 6.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
2.065E-8
|
3.507E-5
|
3.297E-4
|
1.403E-4
|
13
|
137
|
5
|
M5275
|
Genes up-regulated in blood samples from bladder cancer patients.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
5.187E-8
|
6.016E-5
|
5.655E-4
|
3.524E-4
|
21
|
404
|
6
|
M12591
|
Genes up-regulated by 3 h of euglycemic hyperinsulinemic clamp in the vastus lateralis muscle of healthy lean subjects.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
5.314E-8
|
6.016E-5
|
5.655E-4
|
3.610E-4
|
22
|
442
|
7
|
M1613
|
Transcripts depleted in pseudopodia of NIH/3T3 cells (fibroblast) in response to the chemotactic migration stimulus by lysophosphatidic acid (LPA) [PubChem=3988].
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
9.518E-8
|
9.237E-5
|
8.683E-4
|
6.466E-4
|
22
|
457
|
8
|
M4665
|
Genes down-regulated in glomeruli of kidneys from patients with diabetic nephropathy (type 2 diabetes mellitus).
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
1.728E-7
|
1.323E-4
|
1.244E-3
|
1.174E-3
|
21
|
434
|
9
|
M2855
|
Genes up-regulated in NOMO-1 cells (AML) after knockdown of STK33 [Gene ID=65975] by RNAi.
|
MSigDB C6: Oncogenic Signatures (v5.1)
|
1.955E-7
|
1.323E-4
|
1.244E-3
|
1.328E-3
|
17
|
291
|
10
|
M12029
|
Genes selected in supervised analyses to discriminate cells expressing activated HRAS [GeneID=3265] oncogene from control cells expressing GFP.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
2.352E-7
|
1.323E-4
|
1.244E-3
|
1.598E-3
|
16
|
261
|
11
|
GSE15624 3H VS 6H HALOFUGINONE TREATED CD4 TCELL DN
|
Genes down-regulated in CD4 [GeneID=920] T cells treated with halofuginone [PubChem=400772]: 3h versus 6h.
|
MSigDB C7: Immunologic Signatures (v5.1)
|
2.419E-7
|
1.323E-4
|
1.244E-3
|
1.643E-3
|
12
|
141
|
12
|
M13522
|
Common down-regulated transcripts in fibroblasts expressing either XP/CS or TDD mutant forms of ERCC3 [GeneID=2071], after UVC irradiation.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
2.467E-7
|
1.323E-4
|
1.244E-3
|
1.676E-3
|
22
|
483
|
13
|
M10091
|
Genes down-regulated in mucinous ovarian carcinoma tumors of low malignant potential (LMP) compared to normal ovarian surface epithelium tissue.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
2.565E-7
|
1.323E-4
|
1.244E-3
|
1.742E-3
|
14
|
199
|
14
|
M5777
|
Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from patients with type 1 diabetes at 1 month after the diagnosis.
|
MSigDB C7: Immunologic Signatures (v5.1)
|
2.727E-7
|
1.323E-4
|
1.244E-3
|
1.853E-3
|
14
|
200
|
15
|
M8617
|
Potential direct target genes for MIR34A [GeneID=407040] microRNA in IMR32 cells (neuroblastoma).
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
3.535E-7
|
1.601E-4
|
1.505E-3
|
2.401E-3
|
12
|
146
|
16
|
M10355
|
Genes up-regulated in MCV152 cells (ovarian cancer) treated with follicle stimulating hormone (FSH).
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
3.852E-7
|
1.616E-4
|
1.519E-3
|
2.617E-3
|
9
|
74
|
17
|
M14973
|
Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC1 [GeneID=3065] by RNAi.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
4.044E-7
|
1.616E-4
|
1.519E-3
|
2.747E-3
|
21
|
457
|
18
|
M13630
|
Selected genes down-regulated in WS1 (fibroblast) in response to irradiation with high dose UV-C.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
5.212E-7
|
1.967E-4
|
1.849E-3
|
3.541E-3
|
17
|
312
|
19
|
M7514
|
Genes down-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [GeneID=387] off plasmid vector.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
7.134E-7
|
2.476E-4
|
2.328E-3
|
4.846E-3
|
19
|
394
|
20
|
M16975
|
Up-regulated genes in peripheral zone of human pancreatic cancer growing in the pancreas of nude mice compared to that of the tumor from the central zone.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
7.291E-7
|
2.476E-4
|
2.328E-3
|
4.953E-3
|
16
|
284
|
21
|
M8976
|
Down-regulated genes discriminating between MSI (microsatellite instability) and MSS (microsatellite stability) colon cancers.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
8.419E-7
|
2.723E-4
|
2.560E-3
|
5.719E-3
|
9
|
81
|
22
|
M2196
|
Genes significantly de-regulated (p < 0.05) by MIR21 [GeneID=406991] in A172 cells (glioma).
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
9.182E-7
|
2.835E-4
|
2.665E-3
|
6.237E-3
|
16
|
289
|
23
|
M3782
|
Genes down-regulated in ST1 cells (adult T-cell leukemia, ATL) after knockdown of FRA2 [GeneID=2355] by RNAi.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
1.033E-6
|
3.052E-4
|
2.869E-3
|
7.020E-3
|
7
|
43
|
24
|
GSE23925 DARK ZONE VS NAIVE BCELL UP
|
Genes up-regulated in B cells: dark zone versus naïve.
|
MSigDB C7: Immunologic Signatures (v5.1)
|
1.685E-6
|
4.580E-4
|
4.305E-3
|
1.145E-2
|
13
|
200
|
25
|
GSE43863 TFH VS LY6C LOW CXCR5NEG EFFECTOR CD4 TCELL UP
|
Genes up-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: follicular helper (Tfh) versus Ly6c low CXCR5- [GeneID=643].
|
MSigDB C7: Immunologic Signatures (v5.1)
|
1.685E-6
|
4.580E-4
|
4.305E-3
|
1.145E-2
|
13
|
200
|
26
|
M18441
|
Genes down-regulated in samples with systolic heart failure compared to normal hearts.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
2.541E-6
|
6.638E-4
|
6.240E-3
|
1.726E-2
|
14
|
241
|
27
|
M2858
|
Genes up-regulated in NOMO-1 and SKM-1 cells (AML) after knockdown of STK33 [Gene ID=65975] by RNAi.
|
MSigDB C6: Oncogenic Signatures (v5.1)
|
4.269E-6
|
1.074E-3
|
1.010E-2
|
2.900E-2
|
15
|
288
|
28
|
M12676
|
Class NT (non-tolerizeable) genes: induced during the first LPS stimulation and induced at equal or greater degree in tolerant macrophages.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
5.062E-6
|
1.228E-3
|
1.154E-2
|
3.438E-2
|
18
|
409
|
29
|
M4735
|
Genes up-regulated in MCF7 cells (breast cancer) engineered to conditionally express LMO4 [GeneID=8543] by a Tet Off system.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
5.284E-6
|
1.238E-3
|
1.164E-2
|
3.589E-2
|
17
|
370
|
30
|
GSE40274 CTRL VS GATA1 TRANSDUCED ACTIVATED CD4 TCELL DN
|
Genes down-regulated in CD4 T conv: control versus over-expression of GATA1 [GeneID=2623].
|
MSigDB C7: Immunologic Signatures (v5.1)
|
5.545E-6
|
1.256E-3
|
1.180E-2
|
3.767E-2
|
11
|
158
|
31
|
M2155
|
Genes up-regulated during pubertal mammary gland development between week 6 and 7.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
8.241E-6
|
1.418E-3
|
1.334E-2
|
5.598E-2
|
12
|
197
|
32
|
M15150
|
Genes up-regulated in cancer stem cells isolated from mammary tumors compared to the non-tumorigenic cells.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
8.556E-6
|
1.418E-3
|
1.334E-2
|
5.812E-2
|
18
|
425
|
33
|
M6711
|
Genes down-regulated in endothelial cells: untreated versus IFNG [GeneID=3458].
|
MSigDB C7: Immunologic Signatures (v5.1)
|
9.130E-6
|
1.418E-3
|
1.334E-2
|
6.202E-2
|
12
|
199
|
34
|
M3347
|
Genes down-regulated in comparison of dendritic cells (DC) before and 4 h after LPS (TLR4 agonist) stimulation.
|
MSigDB C7: Immunologic Signatures (v5.1)
|
9.130E-6
|
1.418E-3
|
1.334E-2
|
6.202E-2
|
12
|
199
|
35
|
GSE41867 DAY8 VS DAY15 LCMV CLONE13 EFFECTOR CD8 TCELL UP
|
Genes up-regulated in CD8 T effector cells during chronic infection with LCMV-Clone 13: day 8 versus day 15.
|
MSigDB C7: Immunologic Signatures (v5.1)
|
9.606E-6
|
1.418E-3
|
1.334E-2
|
6.525E-2
|
12
|
200
|
36
|
GSE40277 EOS AND LEF1 TRANSDUCED VS CTRL CD4 TCELL UP
|
Genes up-regulated in CD4 [GeneID=920] T conv: over-expressing IKZF4 and LEF1 [GeneID=64375;52276] versus control.
|
MSigDB C7: Immunologic Signatures (v5.1)
|
9.606E-6
|
1.418E-3
|
1.334E-2
|
6.525E-2
|
12
|
200
|
37
|
GSE34006 A2AR KO VS A2AR AGONIST TREATED TREG UP
|
Genes up-regulated in T reg: untreated ADORA2A [GeneID=135] knockout versus wildtype treated by ZM 241385 [PubChem=176407].
|
MSigDB C7: Immunologic Signatures (v5.1)
|
9.606E-6
|
1.418E-3
|
1.334E-2
|
6.525E-2
|
12
|
200
|
38
|
GSE43863 NAIVE VS MEMORY TFH CD4 TCELL D150 LCMV UP
|
Genes up-regulated in CD4 [GeneID=920] SMARTA T cells: naïve versus memory follicular helper (Tfh).
|
MSigDB C7: Immunologic Signatures (v5.1)
|
9.606E-6
|
1.418E-3
|
1.334E-2
|
6.525E-2
|
12
|
200
|
39
|
M3671
|
Genes down-regulated in comparison of regulatory T cell (Treg) from uninfected mice versus T effector cells from uninfected mice.
|
MSigDB C7: Immunologic Signatures (v5.1)
|
9.606E-6
|
1.418E-3
|
1.334E-2
|
6.525E-2
|
12
|
200
|
40
|
M5856
|
Genes up-regulated in comparison of monocytes treated with 5000 ng/ml LPS (TLR4 agonist) versus monocytes treated with anti-TREM1 [GeneID=54210].
|
MSigDB C7: Immunologic Signatures (v5.1)
|
9.606E-6
|
1.418E-3
|
1.334E-2
|
6.525E-2
|
12
|
200
|
41
|
M5779
|
Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from patients with type 1 diabetes at 4 month after the diagnosis.
|
MSigDB C7: Immunologic Signatures (v5.1)
|
9.606E-6
|
1.418E-3
|
1.334E-2
|
6.525E-2
|
12
|
200
|
42
|
M6635
|
Genes up-regulated in bone marrow-derived macrophages with IL10 [GeneID=3486] knockout and 45 min of stimulation by: LPS versus IL6 [GeneID=3469] and LPS.
|
MSigDB C7: Immunologic Signatures (v5.1)
|
9.606E-6
|
1.418E-3
|
1.334E-2
|
6.525E-2
|
12
|
200
|
43
|
M4865
|
Genes up-regulated in comparison of NKT cells versus erythroblasts.
|
MSigDB C7: Immunologic Signatures (v5.1)
|
9.606E-6
|
1.418E-3
|
1.334E-2
|
6.525E-2
|
12
|
200
|
44
|
M3497
|
Genes down-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 40 min.
|
MSigDB C7: Immunologic Signatures (v5.1)
|
9.606E-6
|
1.418E-3
|
1.334E-2
|
6.525E-2
|
12
|
200
|
45
|
M5859
|
Genes down-regulated in comparison of monocytes treated with 5000 ng/ml LPS (TLR4 agonist) versus monocytes treated with control IgG.
|
MSigDB C7: Immunologic Signatures (v5.1)
|
9.606E-6
|
1.418E-3
|
1.334E-2
|
6.525E-2
|
12
|
200
|
46
|
GSE21670 UNTREATED VS IL6 TREATED CD4 TCELL DN
|
Genes down-regulated in CD4 [GeneID=920] T cells: medium versus IL6 [GeneID=3569].
|
MSigDB C7: Immunologic Signatures (v5.1)
|
9.606E-6
|
1.418E-3
|
1.334E-2
|
6.525E-2
|
12
|
200
|
47
|
GSE10422 WT VS BAFF TRANSGENIC LN BCELL UP
|
Genes up-regulated in wildtype B cells versus BAFF-transgenic (over-express TNFSF13B [GeneID=10673]) B cells from lymph node.
|
MSigDB C7: Immunologic Signatures (v5.1)
|
1.054E-5
|
1.523E-3
|
1.432E-2
|
7.158E-2
|
11
|
169
|
48
|
M2293
|
Genes down-regulated in ES (embryonic stem cells) with defficient SUZ12 [GeneID=23512].
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
1.249E-5
|
1.767E-3
|
1.661E-2
|
8.483E-2
|
15
|
315
|
49
|
M5793
|
Down-regulated genes in the canonical gene expression signature of the fibroblast core serum response (CSR) defined by the Stanford group.
|
MSigDB C2: CGP Curated Gene Sets (v5.1)
|
1.496E-5
|
2.059E-3
|
1.936E-2
|
1.016E-1
|
12
|
209
|
50
|
M5942
|
Genes down-regulated in response to ultraviolet (UV) radiation.
|
MSigDB H: Hallmark Gene Sets (v5.1)
|
1.516E-5
|
2.059E-3
|
1.936E-2
|
1.030E-1
|
10
|
144
|