Toppgene analysis for aggregated_1964_log, IC14, negative side

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1: GO: Molecular Function [Display Chart] 231 annotations before applied cutoff / 18819 genes in category

No results to display

2: GO: Biological Process [Display Chart] 1147 annotations before applied cutoff / 18785 genes in category

No results to display

3: GO: Cellular Component [Display Chart] 115 annotations before applied cutoff / 19172 genes in category

No results to display

4: Human Phenotype [Display Chart] 288 annotations before applied cutoff / 4410 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0005474 Decreased calvarial ossification 1.415E-4 2.070E-2
1.292E-1
 4.075E-2 2 7
2 HP:0001320 Cerebellar vermis hypoplasia 1.438E-4 2.070E-2
1.292E-1
 4.140E-2 3 40
3 HP:0000010 Recurrent urinary tract infections 2.128E-3 4.957E-2
3.094E-1
6.128E-1
 2 26
4 HP:0005995 Decreased adipose tissue around neck 2.721E-3 4.957E-2
3.094E-1
7.837E-1
 1 1
5 HP:0030253 Defective T cell proliferation 2.721E-3 4.957E-2
3.094E-1
7.837E-1
 1 1
6 HP:0005602 Progressive vitiligo 2.721E-3 4.957E-2
3.094E-1
7.837E-1
 1 1
7 HP:0005364 Severe viral infections 2.721E-3 4.957E-2
3.094E-1
7.837E-1
 1 1
8 HP:0100518 Dysuria 2.721E-3 4.957E-2
3.094E-1
7.837E-1
 1 1
9 HP:0012279 Hyposerinemia 2.721E-3 4.957E-2
3.094E-1
7.837E-1
 1 1
10 HP:0012277 Hypoglycinemia 2.721E-3 4.957E-2
3.094E-1
7.837E-1
 1 1
11 HP:0000453 Choanal atresia 3.420E-3 4.957E-2
3.094E-1
9.850E-1
 2 33
12 HP:0001838 Rocker bottom foot {has synonym type="layperson"} 4.288E-3 4.957E-2
3.094E-1
1.000E0
 2 37
13 HP:0000239 Large fontanelles 4.288E-3 4.957E-2
3.094E-1
1.000E0
 2 37
14 HP:0005766 Disproportionate shortening of the tibia 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
15 HP:0011414 Hydropic placenta 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
16 HP:0005817 Postaxial polysyndactyly of foot 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
17 HP:0005897 Severe generalized osteoporosis 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
18 HP:0006391 Overtubulated long bones 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
19 HP:0010620 Malar prominence 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
20 HP:0003321 Biconcave flattened vertebrae 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
21 HP:0003489 Acute episodes of neuropathic symptoms 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
22 HP:0009064 Generalized lipodystrophy 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
23 HP:0005253 Increased anterioposterior diameter of thorax 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
24 HP:0008780 Congenital bilateral hip dislocation 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
25 HP:0005873 Polysyndactyly of hallux 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
26 HP:0005005 Femoral bowing present at birth, straightening with time 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
27 HP:0005623 Absent ossification of calvaria 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
28 HP:0001870 Acroosteolysis of distal phalanges (feet) 5.435E-3 4.957E-2
3.094E-1
1.000E0
 1 2
29 HP:0000340 Sloping forehead {has synonym type="layperson"} 6.027E-3 4.957E-2
3.094E-1
1.000E0
 2 44
30 HP:0001622 Premature birth {has synonym type="layperson"} 6.027E-3 4.957E-2
3.094E-1
1.000E0
 2 44
31 HP:0000347 Micrognathia 7.456E-3 4.957E-2
3.094E-1
1.000E0
 4 309
32 HP:0000265 Mastoiditis 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
33 HP:0002203 Respiratory paralysis 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
34 HP:0000292 Loss of facial adipose tissue 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
35 HP:0007394 Prominent superficial blood vessels {has synonym type="layperson"} 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
36 HP:0004349 Reduced bone mineral density 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
37 HP:0002590 Paralytic ileus 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
38 HP:0200041 Skin erosion 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
39 HP:0001070 Mottled pigmentation 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
40 HP:0000320 Bird-like facies 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
41 HP:0000016 Urinary retention 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
42 HP:0007543 Epidermal hyperkeratosis 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
43 HP:0003163 Elevated urinary delta-aminolevulinic acid {has synonym type="layperson"} 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
44 HP:0003023 Bowing of limbs due to multiple fractures 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
45 HP:0000923 Beaded ribs 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
46 HP:0000905 Progressive clavicular acroosteolysis 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
47 HP:0006367 Crumpled long bones {has synonym type="layperson"} 8.143E-3 4.957E-2
3.094E-1
1.000E0
 1 3
48 HP:0001302 Pachygyria 8.980E-3 4.957E-2
3.094E-1
1.000E0
 2 54
49 HP:0009839 Osteolytic defects of the distal phalanges of the hand 1.084E-2 4.957E-2
3.094E-1
1.000E0
 1 4
50 HP:0011802 Hamartoma of tongue 1.084E-2 4.957E-2
3.094E-1
1.000E0
 1 4
Show 45 more annotations

5: Mouse Phenotype [Display Chart] 907 annotations before applied cutoff / 9299 genes in category

No results to display

6: Domain [Display Chart] 404 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PF01023 S 100 Pfam 2.256E-3 2.248E-2
1.479E-1
9.114E-1
 2 27
2 PS00303 S100 CABP PROSITE 2.256E-3 2.248E-2
1.479E-1
9.114E-1
 2 27
3 SM01394 S 100 SMART 2.425E-3 2.248E-2
1.479E-1
9.799E-1
 2 28
4 IPR013787 S100 Ca-bd sub InterPro 2.425E-3 2.248E-2
1.479E-1
9.799E-1
 2 28
5 IPR001751 S100/CaBP-9k CS InterPro 2.425E-3 2.248E-2
1.479E-1
9.799E-1
 2 28
6 IPR022278 Pser aminoTfrase InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
7 IPR032456 Peptidase M48 N InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
8 PF03694 Erg28 Pfam 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
9 IPR033681 ELOVL1 InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
10 SM01348 Nbs1 C SMART 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
11 IPR028481 S100-B InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
12 PS00461 6PGD PROSITE 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
13 IPR006114 6PGDH C InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
14 PF08599 Nbs1 C Pfam 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
15 SM01350 6PGD SMART 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
16 IPR028697 MMP16 InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
17 PF05907 DUF866 Pfam 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
18 IPR000860 HemC InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
19 IPR030083 MAGED1 InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
20 IPR031073 HMGN3 InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
21 IPR027057 CAXX Prtase 1 InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
22 IPR022417 Porphobilin deaminase N InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
23 PS00533 PORPHOBILINOGEN DEAM PROSITE 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
24 IPR013908 DNA-repair Nbs1 C InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
25 IPR012284 6PGD dom 3 InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
26 IPR002740 EVE domain InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
27 IPR016592 Nibrin met InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
28 IPR006113 6PGDH Gnd/GntZ InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
29 IPR028482 S100A11 InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
30 PF16508 NIBRIN BRCT II Pfam 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
31 IPR022419 Porphobilin deaminase cofac BS InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
32 PF16491 Peptidase M48 N Pfam 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
33 IPR017362 DNA-bd RFXANK InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
34 IPR032429 Nibrin BRCT2 InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
35 1.20.5.320 - Gene3D 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
36 IPR022418 Porphobilinogen deaminase C InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
37 PF03900 Porphobil deamC Pfam 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
38 IPR028854 DLC1 InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
39 PF01878 EVE Pfam 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
40 IPR006184 6PGdom BS InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
41 3.30.160.40 - Gene3D 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
42 IPR016819 RNase P/MRP POP5 InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
43 PF00393 6PGD Pfam 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
44 IPR005352 Erg28 InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
45 PF01379 Porphobil deam Pfam 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
46 3.10.590.10 - Gene3D 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
47 IPR008584 DUF866 euk InterPro 2.615E-3 2.248E-2
1.479E-1
1.000E0
 1 1
48 IPR006183 Pgluconate DH InterPro 5.224E-3 3.350E-2
2.204E-1
1.000E0
 1 2
49 IPR008364 Paraoxonase2 InterPro 5.224E-3 3.350E-2
2.204E-1
1.000E0
 1 2
50 PF01435 Peptidase M48 Pfam 5.224E-3 3.350E-2
2.204E-1
1.000E0
 1 2
Show 45 more annotations

7: Pathway [Display Chart] 490 annotations before applied cutoff / 10916 genes in category

No results to display

8: Pubmed [Display Chart] 5870 annotations before applied cutoff / 51853 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 25056061 Biological insights from 108 schizophrenia-associated genetic loci. Pubmed 4.373E-7 1.284E-3 1.188E-2 2.567E-3 6 304
2 19515833:gr Stathmin regulates centrosomal nucleation of microtubules and tubulin dimer/polymer partitioning. GeneRIF 8.748E-7 1.284E-3 1.188E-2 5.135E-3 2 2
3 21087603:gr The tumor suppressor protein DLC1 is regulated by PKD-mediated GAP domain phosphorylation. GeneRIF 8.748E-7 1.284E-3 1.188E-2 5.135E-3 2 2
4 21087603 The tumor suppressor protein DLC1 is regulated by PKD-mediated GAP domain phosphorylation. Pubmed 8.748E-7 1.284E-3 1.188E-2 5.135E-3 2 2
5 23824909 Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. Pubmed 1.456E-6 1.540E-3 1.425E-2 8.546E-3 6 374
6 17981542:gr Loss of p53-regulatory protein IFI16 induces NBS1 leading to activation of p53-mediated checkpoint by phosphorylation of p53 SER37. GeneRIF 2.623E-6 1.540E-3 1.425E-2 1.540E-2 2 3
7 17981542 Loss of p53-regulatory protein IFI16 induces NBS1 leading to activation of p53-mediated checkpoint by phosphorylation of p53 SER37. Pubmed 2.623E-6 1.540E-3 1.425E-2 1.540E-2 2 3
8 19826001 Tensin1 requires protein phosphatase-1alpha in addition to RhoGAP DLC-1 to control cell polarization, migration, and invasion. Pubmed 2.623E-6 1.540E-3 1.425E-2 1.540E-2 2 3
9 19540848:gr Nuclear factor I regulates brain fatty acid-binding protein and glial fibrillary acidic protein gene expression in malignant glioma cell lines. GeneRIF 2.623E-6 1.540E-3 1.425E-2 1.540E-2 2 3
10 19826001:gr Tensin1 requires protein phosphatase-1alpha in addition to RhoGAP DLC-1 to control cell polarization, migration, and invasion. GeneRIF 2.623E-6 1.540E-3 1.425E-2 1.540E-2 2 3
11 7821789 Construction of a human full-length cDNA bank. Pubmed 3.507E-6 1.872E-3 1.732E-2 2.059E-2 4 108
12 22585759:gr Loss of E protein transcription factors E2A and HEB delays memory-precursor formation during the CD8+ T-cell immune response. GeneRIF 5.242E-6 2.198E-3 2.034E-2 3.077E-2 2 4
13 19540848 Nuclear factor I regulates brain fatty acid-binding protein and glial fibrillary acidic protein gene expression in malignant glioma cell lines. Pubmed 5.242E-6 2.198E-3 2.034E-2 3.077E-2 2 4
14 10913138 S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo. Pubmed 5.242E-6 2.198E-3 2.034E-2 3.077E-2 2 4
15 18287524:gr p204 protein overcomes the inhibition of core binding factor alpha-1-mediated osteogenic differentiation by Id helix-loop-helix proteins. GeneRIF 8.732E-6 2.324E-3 2.151E-2
5.126E-2
 2 5
16 11042152 Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. Pubmed 1.266E-5 2.324E-3 2.151E-2
7.429E-2
 5 317
17 16556596:gr p204 protein overcomes the inhibition of the differentiation of P19 murine embryonal carcinoma cells to beating cardiac myocytes by Id proteins. GeneRIF 1.309E-5 2.324E-3 2.151E-2
7.684E-2
 2 6
18 11940648 The MyoD-inducible p204 protein overcomes the inhibition of myoblast differentiation by Id proteins. Pubmed 1.831E-5 2.324E-3 2.151E-2
1.075E-1
 2 7
19 25640309 Systematic identification of molecular links between core and candidate genes in breast cancer. Pubmed 3.528E-5 2.324E-3 2.151E-2
2.071E-1
 4 194
20 21319273 An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells. Pubmed 3.708E-5 2.324E-3 2.151E-2
2.177E-1
 5 397
21 18160256 A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB. Pubmed 3.918E-5 2.324E-3 2.151E-2
2.300E-1
 2 10
22 11745344 Pronounced up-regulation of the PA28alpha/beta proteasome regulator but little increase in the steady-state content of immunoproteasome during dendritic cell maturation. Pubmed 3.918E-5 2.324E-3 2.151E-2
2.300E-1
 2 10
23 16714300 Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity. Pubmed 4.785E-5 2.324E-3 2.151E-2
2.809E-1
 2 11
24 9242638 Differential interactions of Id proteins with basic-helix-loop-helix transcription factors. Pubmed 4.785E-5 2.324E-3 2.151E-2
2.809E-1
 2 11
25 23166591 Nucleolar protein trafficking in response to HIV-1 Tat: rewiring the nucleolus. Pubmed 5.522E-5 2.324E-3 2.151E-2
3.241E-1
 3 77
26 21630459 Proteomic characterization of the human sperm nucleus. Pubmed 5.839E-5 2.324E-3 2.151E-2
3.428E-1
 5 437
27 7759097 Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family. Pubmed 1.041E-4 2.324E-3 2.151E-2
6.110E-1
 2 16
28 7776974 Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. Pubmed 1.326E-4 2.324E-3 2.151E-2
7.781E-1
 2 18
29 15303970 Characterization of Staufen 1 ribonucleoprotein complexes. Pubmed 2.588E-4 2.324E-3 2.151E-2
1.000E0
 2 25
30 26735018 An ID2-dependent mechanism for VHL inactivation in cancer. Pubmed 2.802E-4 2.324E-3 2.151E-2
1.000E0
 2 26
31 17558393 Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility. Pubmed 4.533E-4 2.324E-3 2.151E-2
1.000E0
 2 33
32 22688191 Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. Pubmed 5.102E-4 2.324E-3 2.151E-2
1.000E0
 2 35
33 26687479 The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis. Pubmed 5.411E-4 2.324E-3 2.151E-2
1.000E0
 4 396
34 25147182 Quantitative Lys-¿-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1. Pubmed 5.671E-4 2.324E-3 2.151E-2
1.000E0
 4 401
35 8811196 Structure and functions of the 20S and 26S proteasomes. Pubmed 5.704E-4 2.324E-3 2.151E-2
1.000E0
 2 37
36 23263863 GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. Pubmed 5.704E-4 2.324E-3 2.151E-2
1.000E0
 2 37
37 23864651 The identification of novel proteins that interact with the GLP-1 receptor and restrain its activity. Pubmed 6.668E-4 2.324E-3 2.151E-2
1.000E0
 2 40
38 10893419 Degradation of HIV-1 integrase by the N-end rule pathway. Pubmed 7.006E-4 2.324E-3 2.151E-2
1.000E0
 2 41
39 9079628 HIV-1 tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation. Pubmed 7.006E-4 2.324E-3 2.151E-2
1.000E0
 2 41
40 14550573 Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits. Pubmed 7.006E-4 2.324E-3 2.151E-2
1.000E0
 2 41
41 12419264 The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing. Pubmed 7.006E-4 2.324E-3 2.151E-2
1.000E0
 2 41
42 12914693 Death by deamination: a novel host restriction system for HIV-1. Pubmed 7.352E-4 2.324E-3 2.151E-2
1.000E0
 2 42
43 12920286 Virology. Weapons of mutational destruction. Pubmed 7.352E-4 2.324E-3 2.151E-2
1.000E0
 2 42
44 12750511 Hypermutation of HIV-1 DNA in the absence of the Vif protein. Pubmed 7.352E-4 2.324E-3 2.151E-2
1.000E0
 2 42
45 12719574 Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions. Pubmed 7.352E-4 2.324E-3 2.151E-2
1.000E0
 2 42
46 12840737 Good to CU. Pubmed 7.352E-4 2.324E-3 2.151E-2
1.000E0
 2 42
47 9846577 Evidence for a newly discovered cellular anti-HIV-1 phenotype. Pubmed 7.352E-4 2.324E-3 2.151E-2
1.000E0
 2 42
48 14614829 The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G. Pubmed 7.352E-4 2.324E-3 2.151E-2
1.000E0
 2 42
49 9811770 An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein. Pubmed 7.352E-4 2.324E-3 2.151E-2
1.000E0
 2 42
50 12830140 DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses. Pubmed 7.352E-4 2.324E-3 2.151E-2
1.000E0
 2 42
Show 45 more annotations

9: Interaction [Display Chart] 1949 annotations before applied cutoff / 16534 genes in category

No results to display

10: Cytoband [Display Chart] 47 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 3q13.2-q21 3q13.2-q21 1.414E-3 3.322E-2
1.474E-1
6.644E-2
 1 1
2 1p36.13-p36.12 1p36.13-p36.12 1.414E-3 3.322E-2
1.474E-1
6.644E-2
 1 1
3 1p34.1 1p34.1 2.973E-3 4.658E-2
2.067E-1
1.397E-1
 2 57
4 1p31.3-p31.2 1p31.3-p31.2 4.235E-3 4.852E-2
2.153E-1
1.991E-1
 1 3
5 12q24.31 12q24.31 5.907E-3 4.852E-2
2.153E-1
2.776E-1
 2 81
6 11q23.3 11q23.3 6.193E-3 4.852E-2
2.153E-1
2.911E-1
 2 83
Show 1 more annotation

11: Transcription Factor Binding Site [Display Chart] 373 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$GFI1 01 V$GFI1 01 1.314E-4 4.903E-2
3.187E-1
 4.903E-2 6 219

12: Gene Family [Display Chart] 38 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 459 S100 calcium binding proteins|EF-hand domain containing genenames.org 6.557E-4 2.492E-2
1.053E-1
 2.492E-2 2 21
2 690 Proteasome genenames.org 2.750E-3 3.434E-2
1.452E-1
1.045E-1
 2 43
3 1344 BRCA1 C complex|MRN complex genenames.org 5.432E-3 3.434E-2
1.452E-1
2.064E-1
 1 3
4 463 Paraoxonases genenames.org 5.432E-3 3.434E-2
1.452E-1
2.064E-1
 1 3
5 1138 Stathmins genenames.org 7.236E-3 3.434E-2
1.452E-1
2.750E-1
 1 4
6 574 Hyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing genenames.org 7.236E-3 3.434E-2
1.452E-1
2.750E-1
 1 4
7 1217 Brain expressed X-linked family genenames.org 9.037E-3 3.434E-2
1.452E-1
3.434E-1
 1 5
8 995 Pyrin domain containing|Pyrin and HIN domain family genenames.org 9.037E-3 3.434E-2
1.452E-1
3.434E-1
 1 5
9 1052 I-set domain containing|IgLON cell adhesion molecules genenames.org 9.037E-3 3.434E-2
1.452E-1
3.434E-1
 1 5
10 1336 Ring finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex genenames.org 9.037E-3 3.434E-2
1.452E-1
3.434E-1
 1 5
Show 5 more annotations

13: Coexpression [Display Chart] 3750 annotations before applied cutoff / 21867 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M2115 Genes correlated with proneural type of glioblastoma multiforme tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.707E-6 8.333E-3
7.339E-2
 1.015E-2 6 177
2 GSE40274 FOXP3 VS FOXP3 AND LEF1 TRANSDUCED ACTIVATED CD4 TCELL UP Genes up-regulated in CD4 T conv over-expressing: FOXP3 [GeneID=50943] versus LEF1 and FOXP3 [GeneID=51176;50943]. MSigDB C7: Immunologic Signatures (v5.1) 5.474E-6 8.333E-3
7.339E-2
 2.053E-2 6 200
3 M2081 Genes down-regulated by TGFB1 [GeneID=7040] in MEF cells (embryonic fibroblast) via TGFB1R [GeneID=7046]. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.667E-6 8.333E-3
7.339E-2
 2.500E-2 6 207
4 M16830 Genes down-regulated in LNCaP cells (prostate cancer) in response to synthetic androgen R1881 [PubChem=13766]. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.990E-6 9.366E-3
8.249E-2
 3.746E-2 3 19
5 M9343 Down-regulated genes in hepatocellular carcinoma (HCC) subclass G5, defined by unsupervised clustering. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.978E-5 1.208E-2
1.063E-1
1.117E-1
 3 27
6 M3456 Genes identified by ChIP within the high-affinity group of MYC [GeneID=4609] targets. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.357E-5 1.208E-2
1.063E-1
2.009E-1
 5 182
7 M7013 Upregulated in the vastus lateralis muscle of middle aged rhesus monkeys subjected to caloric restriction since young adulthood vs age matched controls MSigDB C2: CGP Curated Gene Sets (v5.1) 6.097E-5 1.208E-2
1.063E-1
2.286E-1
 4 95
8 M17859 Genes down-regulated in UB27 cells (osteosarcoma) at any time point after inducing the expression of a mutant form of WT1 [GeneID=7490]. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.877E-5 1.208E-2
1.063E-1
2.579E-1
 7 459
9 M2293 Genes down-regulated in ES (embryonic stem cells) with defficient SUZ12 [GeneID=23512]. MSigDB C2: CGP Curated Gene Sets (v5.1) 7.074E-5 1.208E-2
1.063E-1
2.653E-1
 6 315
10 M7439 Genes down-regulated in fibroblasts expressing different mutant forms of ERCC3 [GeneID=2071]: XP/CS (xeroderma pigmentosum (XP) and Cockraine's syndrome (CS)) vs TTD (trichothiodystrophy). MSigDB C2: CGP Curated Gene Sets (v5.1) 7.167E-5 1.208E-2
1.063E-1
2.688E-1
 3 36
11 GSE28783 ANTI MIR33 VS CTRL ATHEROSCLEROSIS MACROPHAGE DN Genes down-regulated in atherosclerosis macrophages: anti miR-33 versus anti miR. MSigDB C7: Immunologic Signatures (v5.1) 7.984E-5 1.208E-2
1.063E-1
2.994E-1
 5 198
12 M5044 Genes up-regulated in comparison of splenic primary CD8 effector T cells at day 8 post-chronic infection versus splenic secondary CD8 effector T cells at day 8 post-chronic infection. MSigDB C7: Immunologic Signatures (v5.1) 8.176E-5 1.208E-2
1.063E-1
3.066E-1
 5 199
13 M5048 Genes down-regulated in comparison of splenic primary CD8 effector T cells at day 8 post-acute infection versus splenic primary CD8 effector T cells at day 8 post-chronic infection. MSigDB C7: Immunologic Signatures (v5.1) 8.176E-5 1.208E-2
1.063E-1
3.066E-1
 5 199
14 GSE29949 MICROGLIA BRAIN VS MONOCYTE BONE MARROW DN Genes down-regulated in brain microglia versus bone marrow monocytes. MSigDB C7: Immunologic Signatures (v5.1) 8.372E-5 1.208E-2
1.063E-1
3.140E-1
 5 200
15 M3441 Genes up-regulated in comparison of intrathymic T progenitor cells (ITTP) versus naive CD4 [GeneID=920] T cells from cord blood. MSigDB C7: Immunologic Signatures (v5.1) 8.372E-5 1.208E-2
1.063E-1
3.140E-1
 5 200
16 GSE33162 UNTREATED VS 4H LPS STIM HDAC3 KO MACROPHAGE DN Genes down-regulated in macrophages with knockout of HDAC3 [GeneID=8841]: untreated versus LPS. MSigDB C7: Immunologic Signatures (v5.1) 8.372E-5 1.208E-2
1.063E-1
3.140E-1
 5 200
17 GSE42021 TREG VS TCONV PLN UP Genes up-regulated in cells from peripheral lymph nodes: T reg versus T conv. MSigDB C7: Immunologic Signatures (v5.1) 8.372E-5 1.208E-2
1.063E-1
3.140E-1
 5 200
18 GSE21360 PRIMARY VS TERTIARY MEMORY CD8 TCELL UP Genes up-regulated in memory CD8 T cells: 1' versus 3'. MSigDB C7: Immunologic Signatures (v5.1) 8.372E-5 1.208E-2
1.063E-1
3.140E-1
 5 200
19 M4525 Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th1 cells at 48 h. MSigDB C7: Immunologic Signatures (v5.1) 8.372E-5 1.208E-2
1.063E-1
3.140E-1
 5 200
20 M3509 Genes up-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 360 min. MSigDB C7: Immunologic Signatures (v5.1) 8.372E-5 1.208E-2
1.063E-1
3.140E-1
 5 200
21 GSE22935 24H VS 48H MBOVIS BCG STIM MYD88 KO MACROPHAGE UP Genes up-regulated in macrophages with MYD88 [GeneID=4615] knockout after M. bovis BCG infection: 24h versus 48h. MSigDB C7: Immunologic Signatures (v5.1) 8.372E-5 1.208E-2
1.063E-1
3.140E-1
 5 200
22 M5924 Genes up-regulated through activation of mTORC1 complex. MSigDB H: Hallmark Gene Sets (v5.1) 8.372E-5 1.208E-2
1.063E-1
3.140E-1
 5 200
23 M3607 Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 72 h. MSigDB C7: Immunologic Signatures (v5.1) 8.372E-5 1.208E-2
1.063E-1
3.140E-1
 5 200
24 M4194 Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 12 h. MSigDB C7: Immunologic Signatures (v5.1) 8.372E-5 1.208E-2
1.063E-1
3.140E-1
 5 200
25 GSE33424 CD161 HIGH VS NEG CD8 TCELL DN Genes down-regulated in CD8 T cells: KLRB1 high [GeneID=3820] versus KLRB1- [GeneID=3820]. MSigDB C7: Immunologic Signatures (v5.1) 8.372E-5 1.208E-2
1.063E-1
3.140E-1
 5 200
26 M6892 Genes down-regulated in CD4 [GeneID=920] T cells with in vivo expansion: IL6 [GeneID=3569] versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v5.1) 8.372E-5 1.208E-2
1.063E-1
3.140E-1
 5 200
27 M3185 Genes down-regulated in at least one of three multiple myeloma (MM) cell lines treated with the DNA hypomethylating agent decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.006E-5 1.251E-2
1.102E-1
3.377E-1
 4 105
28 M14601 Genes up-regulated in hepatoblastoma samples compared to normal liver tissue. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.844E-5 1.318E-2
1.161E-1
3.692E-1
 5 207
29 M27 Set 'Myc targets1': targets of c-Myc [GeneID=4609] identified by ChIP on chip in cultured cell lines, focusing on E-box-containing genes; high affinity bound subset MSigDB C2: CGP Curated Gene Sets (v5.1) 1.612E-4 2.085E-2
1.836E-1
6.045E-1
 5 230
30 GSE12707 AT16L1 HYPOMORPH VS WT THYMUS UP Genes up-regulated in tymocytes: mutant (hypomorph) ATG16L1 [GeneID=55054] versus wildtype. MSigDB C7: Immunologic Signatures (v5.1) 1.713E-4 2.141E-2
1.886E-1
6.424E-1
 4 124
31 M5311 Genes from 'subtype S1' signature of hepatocellular carcinoma (HCC): aberrant activation of the WNT signaling pathway. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.853E-4 2.242E-2
1.974E-1
6.950E-1
 5 237
32 M18441 Genes down-regulated in samples with systolic heart failure compared to normal hearts. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.003E-4 2.347E-2
2.067E-1
7.512E-1
 5 241
33 M2446 Genes down-regulated in MEF cells (embryonic fibroblast) upon stimulation with TGFB1 [GeneID=7040] for 10 h. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.121E-4 2.411E-2
2.123E-1
7.955E-1
 5 244
34 M4680 Genes up-regulated in RD cells (embryonal rhabdomyosarcoma, ERMS) by expression of PAX3- or PAX7-FOXO1 [GeneID=5077;5081;2308] fusions off retroviral vectors. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.601E-4 2.869E-2
2.526E-1
9.754E-1
 5 255
35 M5942 Genes down-regulated in response to ultraviolet (UV) radiation. MSigDB H: Hallmark Gene Sets (v5.1) 3.036E-4 3.240E-2
2.854E-1
1.000E0
 4 144
36 M7030 Genes down-regulated in MCF7 cells (breast cancer) treated with hypoxia mimetic DMOG [PubChem=3080614]. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.147E-4 3.240E-2
2.854E-1
1.000E0
 3 59
37 M2506 Genes up-regulated in the neural crest stem cells (NCS), defined as p75+/HNK1+ [GeneID=4804;27087]. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.199E-4 3.240E-2
2.854E-1
1.000E0
 4 146
38 M16336 Up-regulated genes in MM1.S cells (multiple myeloma) treated with adaphostin [PubChem=387042], a tyrosine kinase inhibitor with anticancer properties. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.283E-4 3.240E-2
2.854E-1
1.000E0
 4 147
39 M11038 Experimentally validated direct targets of MIR192 [GeneID=406967] microRNA; MIR192 caused cell cycle arrest in HCT116 cells (colon cancer). MSigDB C2: CGP Curated Gene Sets (v5.1) 3.644E-4 3.343E-2
2.944E-1
1.000E0
 3 62
40 M7623 Genes down-regulated in multiple myeloma (MM) cell lines treated with both decitabine [PubChem=451668] TSA [PubChem=5562]. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.061E-4 3.343E-2
2.944E-1
1.000E0
 5 281
41 GSE11386 NAIVE VS MEMORY BCELL DN Genes down-regulated in B lymphocytes: naïve versus memory. MSigDB C7: Immunologic Signatures (v5.1) 4.113E-4 3.343E-2
2.944E-1
1.000E0
 4 156
42 M16975 Up-regulated genes in peripheral zone of human pancreatic cancer growing in the pancreas of nude mice compared to that of the tumor from the central zone. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.263E-4 3.343E-2
2.944E-1
1.000E0
 5 284
43 M14985 Genes up-regulated in SKOC-3 cells (ovarian cancer) after YB-1 (YBX1) [GeneID=4904] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.689E-4 3.343E-2
2.944E-1
1.000E0
 5 290
44 GSE40274 CTRL VS XBP1 TRANSDUCED ACTIVATED CD4 TCELL DN Genes down-regulated in CD4 T conv: control versus over-expression of XBP1 [GeneID=7494]. MSigDB C7: Immunologic Signatures (v5.1) 4.855E-4 3.343E-2
2.944E-1
1.000E0
 4 163
45 M5588 Genes up-regulated during differentiation from large pre-BII to small pre-BII lymphocyte. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.855E-4 3.343E-2
2.944E-1
1.000E0
 4 163
46 M13251 Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 14 h time point that were not down-regulated at the previous time point, 12 h. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.226E-4 3.343E-2
2.944E-1
1.000E0
 5 297
47 GSE14415 INDUCED TREG VS FOXP3 KO INDUCED TREG IL2 CULTURE UP Genes up-regulated in induced T reg cultured with IL2 [GeneID=3558]: wildtype versus non-functional FOXP3 [GeneID=50943]. MSigDB C7: Immunologic Signatures (v5.1) 5.440E-4 3.343E-2
2.944E-1
1.000E0
 4 168
48 M1126 Genes up-regulated in malignant skin tumors (squamous cell carcinoma, SCC) formed by treatment with DMBA and TPA [PubChem=6001;4792] in the two stage skin carcinogenesis model. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.786E-4 3.343E-2
2.944E-1
1.000E0
 2 16
49 M3903 Genes changed in LSK cells (bone marrow) as a function of a QTL for the size of hematopoietic stem cell (HSC) population: comparison of reciprocal congenic strains D.B. Chr3 (DB), B.D. Chr3 (BD) and the parental strains B6 and D2. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.548E-4 3.343E-2
2.944E-1
1.000E0
 2 17
50 M12393 Selected genes down-regulated in prostate tumors developed by transgenic mice overexpressing VAV3 [GeneID=10451] in prostate epithelium. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.548E-4 3.343E-2
2.944E-1
1.000E0
 2 17
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 1569 annotations before applied cutoff / 20974 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 54Dn Top 500 All 54Dn Top 500 All Brain Map - Allen iN 6.936E-11 1.088E-7 8.637E-7 1.088E-7 13 493
2 astrocytes Top 500 All astrocytes Top 500 All Brain Map - Barres 1.796E-7 1.409E-4 1.118E-3 2.818E-4 10 496
3 Lungmap Mouse e16.5 Proliferative fibroblast Top 500 Cluster 2 Mouse Lung E16.5 Proliferative fibroblast top 500 c2 Lungmap Mouse Single Cell (Lungmap.net) 5.980E-7 3.109E-4 2.467E-3 9.383E-4 4 29
4 Lungmap Mouse e14.5 Epithelial (GSE52583) Top 500 All Mouse Lung E14.5 Epithelial top 500 Lungmap Mouse Single Cell (Lungmap.net) 7.926E-7 3.109E-4 2.467E-3 1.244E-3 9 446
5 OPC Top 500 Cluster 4 OPC Top 500 Cluster 4 Brain Map - Barres 5.155E-6 1.618E-3 1.284E-2 8.088E-3 4 49
6 Lungmap Mouse e16.5 Epithelial (GSE52583) Top 500 All Mouse Lung E16.5 Epithelial GSE52583 top 500 Lungmap Mouse Single Cell (Lungmap.net) 6.872E-6 1.797E-3 1.426E-2 1.078E-2 8 435
7 astrocytes Top 500 Cluster 0 astrocytes Top 500 Cluster 0 Brain Map - Barres 1.088E-5 2.012E-3 1.597E-2 1.708E-2 4 59
8 oligodendrocytes Top 500 Cluster 2 oligodendrocytes Top 500 Cluster 2 Brain Map - Barres 1.088E-5 2.012E-3 1.597E-2 1.708E-2 4 59
9 80Dn SubClass 80Dn 5 Top 500 All 80Dn SubClass 80Dn 5 Top 500 All Brain Map - Allen iN 1.282E-5 2.012E-3 1.597E-2 2.012E-2 8 474
10 80Dn SubClass 80Dn 5 Top 500 Cluster 0 80Dn SubClass 80Dn 5 Top 500 Cluster 0 Brain Map - Allen iN 1.282E-5 2.012E-3 1.597E-2 2.012E-2 8 474
11 54SK Top 500 All 54SK Top 500 All Brain Map - Allen iN 1.582E-5 2.051E-3 1.628E-2 2.482E-2 8 488
12 80Dn Top 500 All 80Dn Top 500 All Brain Map - Allen iN 1.727E-5 2.051E-3 1.628E-2 2.710E-2 8 494
13 OPC Top 500 All OPC Top 500 All Brain Map - Barres 1.727E-5 2.051E-3 1.628E-2 2.710E-2 8 494
14 26Dn SubClass 26Dn 2 Top 500 All 26Dn SubClass 26Dn 2 Top 500 All Brain Map - Allen iN 1.830E-5 2.051E-3 1.628E-2 2.872E-2 8 498
15 26Dp Top 500 Cluster 3 26Dp Top 500 Cluster 3 Brain Map - Allen iN 2.343E-5 2.451E-3 1.945E-2 3.676E-2 3 24
16 Lungmap Mouse e16.5 Endothelial SubClass Matrix Endothelial Top 500 Cluster 2 Mouse Lung E16.5 Endothelial Matrix Endothelial c2 Lungmap Mouse Single Cell (Lungmap.net) 2.658E-5 2.607E-3 2.068E-2 4.170E-2 3 25
17 fetal replicating Top 500 Cluster 3 fetal replicating Top 500 Cluster 3 Brain Map - Barres 6.223E-5 5.743E-3 4.558E-2
9.764E-2
 3 33
18 Lungmap Mouse e14.5 Epithelial (GSE52583) Top 500 Cluster 1 Mouse Lung E14.5 Epithelial top 500 c1 Lungmap Mouse Single Cell (Lungmap.net) 7.457E-5 6.500E-3
5.158E-2
1.170E-1
 4 96
19 Lungmap Mouse e16.5 Matrix fibroblast SubClass Intermediate Fibroblast Top 500 Cluster 1 Mouse Lung E16.5 Matrix Fibroblast Intermediate Fibroblast c1 Lungmap Mouse Single Cell (Lungmap.net) 8.804E-5 7.184E-3
5.701E-2
1.381E-1
 3 37
20 54Dn SubClass 54Dn 1SK Top 500 All 54Dn SubClass 54Dn 1SK Top 500 All Brain Map - Allen iN 9.158E-5 7.184E-3
5.701E-2
1.437E-1
 7 461
21 54Dn SubClass 54Dn 4 Top 500 All 54Dn SubClass 54Dn 4 Top 500 All Brain Map - Allen iN 1.287E-4 9.324E-3
7.399E-2
2.020E-1
 7 487
22 Facebase ST1 e10.5 NeuroEpith CentrlOverEmin 250 e10.5 NeuroEpith CentrlOverEmin top-relative-expression-ranked 250 FaceBase_ST1 1.307E-4 9.324E-3
7.399E-2
2.051E-1
 5 211
23 neurons SubClass CRH-med Top 500 Cluster 3 neurons SubClass CRH-med Top 500 Cluster 3 Brain Map - Barres 1.385E-4 9.446E-3
7.496E-2
2.173E-1
 3 43
24 PCBC ratio EB blastocyst vs EB bone marrow cfr-2X-p05 EB blastocyst vs EB bone marrow-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 1.604E-4 1.049E-2
8.323E-2
2.517E-1
 6 351
25 26Dn Top 500 Cluster 4 26Dn Top 500 Cluster 4 Brain Map - Allen iN 2.443E-4 1.533E-2
1.217E-1
3.833E-1
 3 52
26 neurons SubClass CRH-hi Top 500 Cluster 1 neurons SubClass CRH-hi Top 500 Cluster 1 Brain Map - Barres 2.586E-4 1.560E-2
1.238E-1
4.057E-1
 3 53
27 54Dn Top 500 Cluster 0 54Dn Top 500 Cluster 0 Brain Map - Allen iN 3.021E-4 1.756E-2
1.393E-1
4.740E-1
 4 138
28 Facebase ST1 e10.5 NeuroEpith CentrlOverEmin 500 e10.5 NeuroEpith CentrlOverEmin top-relative-expression-ranked 500 FaceBase_ST1 3.744E-4 1.906E-2
1.513E-1
5.875E-1
 6 411
29 54Dn SubClass 54Dn 4 Top 500 Cluster 3 54Dn SubClass 54Dn 4 Top 500 Cluster 3 Brain Map - Allen iN 3.921E-4 1.906E-2
1.513E-1
6.151E-1
 3 61
30 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k1 200 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k-means-cluster#1 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 3.921E-4 1.906E-2
1.513E-1
6.151E-1
 3 61
31 Lungmap Mouse e18.5 Epithelial (GSE52583) SubClass AT1 Top 500 Cluster 3 Mouse Lung E18.5 Epithelial AT1 c3 Lungmap Mouse Single Cell (Lungmap.net) 4.113E-4 1.906E-2
1.513E-1
6.454E-1
 3 62
32 54Dn SubClass 54Dn 1SK Top 500 Cluster 0 54Dn SubClass 54Dn 1SK Top 500 Cluster 0 Brain Map - Allen iN 4.113E-4 1.906E-2
1.513E-1
6.454E-1
 3 62
33 GSM476664 500 gamma delta T cells, Tgd.vg3+24alo.e17.Th, TCRd+ Vg3+ CD24-, Fetal Thymus, avg-3 Immgen.org, GSE15907 4.148E-4 1.906E-2
1.513E-1
6.507E-1
 6 419
34 Lungmap Mouse e16.5 Matrix fibroblast SubClass Intermediate Fibroblast Top 500 All Mouse Lung E16.5 Intermediate Fibroblast top 500 Lungmap Mouse Single Cell (Lungmap.net) 4.200E-4 1.906E-2
1.513E-1
6.590E-1
 6 420
35 gudmap developingLowerUrinaryTract P1 ureter 1000 k4 DevelopingLowerUrinaryTract P1 ureter emap-30363 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.252E-4 1.906E-2
1.513E-1
6.671E-1
 4 151
36 gudmap dev gonad e11.5 F GonadVasMes Flk 500 dev gonad e11.5 F GonadVasMes Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 4.416E-4 1.925E-2
1.527E-1
6.929E-1
 6 424
37 gudmap dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 k4 1000 dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 4.749E-4 1.973E-2
1.566E-1
7.450E-1
 5 279
38 Lungmap Mouse e16.5 Pericyte Top 500 Cluster 1 Mouse Lung E16.5 Pericyte top 500 c1 Lungmap Mouse Single Cell (Lungmap.net) 4.779E-4 1.973E-2
1.566E-1
7.498E-1
 2 14
39 GSM777046 500 Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4 Immgen.org, GSE15907 5.242E-4 2.109E-2
1.674E-1
8.225E-1
 6 438
40 54Dn SubClass 54Dn 5 Top 500 Cluster 1 54Dn SubClass 54Dn 5 Top 500 Cluster 1 Brain Map - Allen iN 5.506E-4 2.129E-2
1.689E-1
8.639E-1
 2 15
41 gudmap dev gonad e11.5 F ReproVasc Flk k3 1000 dev gonad e11.5 F ReproVasc Flk k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 5.631E-4 2.129E-2
1.689E-1
8.835E-1
 6 444
42 GSM777043 500 Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3 Immgen.org, GSE15907 5.698E-4 2.129E-2
1.689E-1
8.940E-1
 6 445
43 GSM777063 500 Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 6.042E-4 2.184E-2
1.733E-1
9.479E-1
 6 450
44 GSM777067 500 Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2 Immgen.org, GSE15907 6.256E-4 2.184E-2
1.733E-1
9.815E-1
 6 453
45 Lungmap Mouse e16.5 Endothelial Top 500 Cluster 1 Mouse Lung E16.5 Endothelial top 500 c1 Lungmap Mouse Single Cell (Lungmap.net) 6.283E-4 2.184E-2
1.733E-1
9.859E-1
 2 16
46 GSM777055 500 Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4 Immgen.org, GSE15907 6.402E-4 2.184E-2
1.733E-1
1.000E0
 6 455
47 gudmap dev gonad e12.5 F VasAssMesen MafB k4 1000 dev gonad e12.5 F VasAssMesen MafB k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 6.697E-4 2.236E-2
1.774E-1
1.000E0
 5 301
48 Lungmap Mouse e16.5 Epithelial SubClass Proliferative AT1 Progenitor Top 500 Cluster 4 Mouse Lung E16.5 Epithelial Proliferative AT1 Progenitor c4 Lungmap Mouse Single Cell (Lungmap.net) 7.111E-4 2.324E-2
1.844E-1
1.000E0
 2 17
49 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 200 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 7.888E-4 2.526E-2
2.004E-1
1.000E0
 4 178
50 54SK Top 500 Cluster 0 54SK Top 500 Cluster 0 Brain Map - Allen iN 9.106E-4 2.858E-2
2.268E-1
1.000E0
 4 185
Show 45 more annotations

15: Computational [Display Chart] 185 annotations before applied cutoff / 9399 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 module 72 Genes in module 72 MSigDb: C4 - CM: Cancer Modules 1.889E-4 3.495E-2
2.027E-1
 3.495E-2 7 297
2 module 12 Genes in module 12 MSigDb: C4 - CM: Cancer Modules 5.224E-4 4.832E-2
2.803E-1
9.665E-2
 7 351

16: MicroRNA [Display Chart] 702 annotations before applied cutoff / 19844 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-223:miRecords TarBase hsa-miR-223:miRecords TarBase miRecords_TarBase 1.789E-5 1.256E-2
8.957E-2
 1.256E-2 2 3

17: Drug [Display Chart] 9275 annotations before applied cutoff / 22098 genes in category

No results to display

18: Disease [Display Chart] 789 annotations before applied cutoff / 16150 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 umls:C0003469 Anxiety Disorders DisGeNET Curated 5.040E-5 3.976E-2
2.882E-1
 3.976E-2 7 371
2 umls:C2677180 Congenital microcephaly DisGeNET BeFree 1.032E-4 4.070E-2
2.950E-1
8.140E-2
 2 6
3 umls:C0014474 Ependymoma DisGeNET Curated 1.909E-4 4.885E-2
3.541E-1
1.507E-1
 4 108
4 umls:C0265783 Congenital hypoplasia of lung DisGeNET BeFree 8.115E-4 4.885E-2
3.541E-1
6.403E-1
 2 16
5 umls:C1368404 Hypopharyngeal Carcinoma DisGeNET BeFree 9.182E-4 4.885E-2
3.541E-1
7.244E-1
 2 17
6 umls:C1275278 Extraskeletal Myxoid Chondrosarcoma DisGeNET Curated 1.998E-3 4.885E-2
3.541E-1
1.000E0
 2 25
7 cv:C1837756 Mandibuloacral dysplasia with type B lipodystrophy Clinical Variations 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
8 umls:C1851801 EDS VIIB DisGeNET Curated 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
9 umls:C0036310 Scheuermann's Disease DisGeNET BeFree 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
10 cv:C1970253 Phosphoserine aminotransferase deficiency Clinical Variations 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
11 umls:C0024507 Majewski Syndrome DisGeNET Curated 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
12 umls:C4015019 NEU-LAXOVA SYNDROME 2 DisGeNET Curated 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
13 umls:C0268356 Osteogenesis imperfecta with blue sclerae AND normal teeth DisGeNET BeFree 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
14 umls:C4014617 IMMUNODEFICIENCY 24 DisGeNET Curated 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
15 225320 EHLERS-DANLOS SYNDROME, AUTOSOMAL RECESSIVE, CARDIAC VALVULAR FORM OMIM 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
16 umls:C1867969 Porphyria, Acute Intermittent, Nonerythroid Variant DisGeNET Curated 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
17 umls:C1837756 MANDIBULOACRAL DYSPLASIA WITH TYPE B LIPODYSTROPHY DisGeNET Curated 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
18 cv:CN196688 Immunodeficiency 24 Clinical Variations 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
19 608612 MANDIBULOACRAL DYSPLASIA WITH TYPE B LIPODYSTROPHY; MADB OMIM 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
20 cv:C0024507 Short rib-polydactyly syndrome, Majewski type Clinical Variations 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
21 610992 PHOSPHOSERINE AMINOTRANSFERASE DEFICIENCY OMIM 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
22 umls:C3151036 CHROMOSOME 1p32-p31 DELETION SYNDROME DisGeNET Curated 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
23 176000 PORPHYRIA, ACUTE INTERMITTENT OMIM 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
24 umls:C1335907 Polymorphous low grade adenocarcinoma of salivary gland DisGeNET BeFree 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
25 umls:C0018944 Hematoma DisGeNET Curated 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
26 umls:C0279603 Chondroblastic osteosarcoma DisGeNET BeFree 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
27 umls:C1859535 Bare Lymphocyte Syndrome, Type II, Complementation Group B DisGeNET Curated 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
28 umls:C1857034 Ehlers-Danlos syndrome, cardiac valvular form DisGeNET Curated 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
29 611603 LISSENCEPHALY 3; LIS3 OMIM 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
30 cv:CN177972 Craniosynostosis 3 Clinical Variations 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
31 cv:CN219802 Neu-laxova syndrome 2 Clinical Variations 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
32 cv:C0398791 Microcephaly, normal intelligence and immunodeficiency Clinical Variations 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
33 umls:C2937359 Old thrombus DisGeNET BeFree 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
34 cv:C1969029 Lissencephaly 3 Clinical Variations 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
35 umls:C3553958 METAPHYSEAL ENCHONDROMATOSIS WITH D-2-HYDROXYGLUTARIC ACIDURIA DisGeNET Curated 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
36 cv:C1857034 Ehlers-Danlos syndrome, autosomal recessive, cardiac valvular form Clinical Variations 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
37 umls:C1336160 Stage IIA Esophageal Squamous Cell Carcinoma DisGeNET BeFree 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
38 cv:C0162565 Acute intermittent porphyria Clinical Variations 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
39 umls:C1969029 Lissencephaly 3 DisGeNET Curated 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
40 umls:C1970253 Phosphoserine Aminotransferase Deficiency DisGeNET Curated 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
41 umls:C3715051 CRANIOSYNOSTOSIS 3 DisGeNET Curated 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
42 umls:C0795825 Chromosome 8, trisomy 8p DisGeNET BeFree 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
43 251260 NIJMEGEN BREAKAGE SYNDROME OMIM 2.663E-3 4.885E-2
3.541E-1
1.000E0
 1 1
Show 38 more annotations