Toppgene analysis for aggregated_1964_log, IC20, negative side

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1: GO: Molecular Function [Display Chart] 673 annotations before applied cutoff / 18819 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0005201 extracellular matrix structural constituent 9.192E-9 6.186E-6 4.386E-5 6.186E-6 9 78
2 GO:0005178 integrin binding 4.947E-6 1.665E-3 1.180E-2 3.329E-3 8 122
3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding 2.343E-5 4.988E-3 3.536E-2 1.577E-2 12 358
4 GO:0046332 SMAD binding 2.964E-5 4.988E-3 3.536E-2 1.995E-2 6 77
5 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding 1.332E-4 1.793E-2
1.272E-1
8.967E-2
 11 365
6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding 1.934E-4 1.936E-2
1.373E-1
1.302E-1
 9 259
7 GO:0048306 calcium-dependent protein binding 2.117E-4 1.936E-2
1.373E-1
1.425E-1
 5 70
8 GO:0050839 cell adhesion molecule binding 2.301E-4 1.936E-2
1.373E-1
1.549E-1
 8 209
9 GO:0003779 actin binding 3.772E-4 2.821E-2
2.000E-1
2.539E-1
 11 412
Show 4 more annotations

2: GO: Biological Process [Display Chart] 3387 annotations before applied cutoff / 18785 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0030198 extracellular matrix organization 3.375E-11 6.000E-8 5.223E-7 1.143E-7 19 354
2 GO:0043062 extracellular structure organization 3.543E-11 6.000E-8 5.223E-7 1.200E-7 19 355
3 GO:0042063 gliogenesis 5.073E-9 5.728E-6 4.986E-5 1.718E-5 15 282
4 GO:0048608 reproductive structure development 2.466E-7 1.768E-4 1.539E-3 8.352E-4 17 490
5 GO:0061458 reproductive system development 2.765E-7 1.768E-4 1.539E-3 9.364E-4 17 494
6 GO:0001763 morphogenesis of a branching structure 3.317E-7 1.768E-4 1.539E-3 1.123E-3 12 238
7 GO:0030335 positive regulation of cell migration 3.654E-7 1.768E-4 1.539E-3 1.238E-3 16 446
8 GO:0040013 negative regulation of locomotion 4.927E-7 1.814E-4 1.579E-3 1.669E-3 13 295
9 GO:0001667 ameboidal-type cell migration 5.098E-7 1.814E-4 1.579E-3 1.727E-3 14 347
10 GO:2000147 positive regulation of cell motility 5.355E-7 1.814E-4 1.579E-3 1.814E-3 16 459
11 GO:0051272 positive regulation of cellular component movement 7.532E-7 2.026E-4 1.764E-3 2.551E-3 16 471
12 GO:0060541 respiratory system development 7.831E-7 2.026E-4 1.764E-3 2.652E-3 12 258
13 GO:0010001 glial cell differentiation 8.254E-7 2.026E-4 1.764E-3 2.796E-3 11 213
14 GO:0035239 tube morphogenesis 8.374E-7 2.026E-4 1.764E-3 2.836E-3 15 417
15 GO:0040017 positive regulation of locomotion 9.144E-7 2.065E-4 1.797E-3 3.097E-3 16 478
16 GO:0051271 negative regulation of cellular component movement 1.215E-6 2.413E-4 2.101E-3 4.117E-3 12 269
17 GO:0061138 morphogenesis of a branching epithelium 1.240E-6 2.413E-4 2.101E-3 4.200E-3 11 222
18 GO:0060562 epithelial tube morphogenesis 1.283E-6 2.413E-4 2.101E-3 4.344E-3 14 375
19 GO:0050678 regulation of epithelial cell proliferation 1.512E-6 2.695E-4 2.346E-3 5.120E-3 13 326
20 GO:0048754 branching morphogenesis of an epithelial tube 1.759E-6 2.866E-4 2.495E-3 5.957E-3 10 185
21 GO:0002576 platelet degranulation 1.777E-6 2.866E-4 2.495E-3 6.018E-3 8 107
22 GO:0035264 multicellular organism growth 2.133E-6 3.285E-4 2.859E-3 7.226E-3 10 189
23 GO:0022612 gland morphogenesis 3.105E-6 4.383E-4 3.815E-3 1.052E-2 9 154
24 GO:0090130 tissue migration 3.106E-6 4.383E-4 3.815E-3 1.052E-2 11 244
25 GO:0050769 positive regulation of neurogenesis 3.388E-6 4.591E-4 3.996E-3 1.148E-2 15 467
26 GO:0048863 stem cell differentiation 4.171E-6 5.411E-4 4.710E-3 1.413E-2 12 303
27 GO:0061551 trigeminal ganglion development 4.454E-6 5.411E-4 4.710E-3 1.509E-2 3 5
28 GO:0043491 protein kinase B signaling 4.473E-6 5.411E-4 4.710E-3 1.515E-2 9 161
29 GO:0007266 Rho protein signal transduction 4.948E-6 5.757E-4 5.011E-3 1.676E-2 9 163
30 GO:0006929 substrate-dependent cell migration 5.099E-6 5.757E-4 5.011E-3 1.727E-2 5 33
31 GO:0051897 positive regulation of protein kinase B signaling 5.736E-6 6.267E-4 5.455E-3 1.943E-2 7 89
32 GO:0001101 response to acid chemical 6.405E-6 6.779E-4 5.902E-3 2.169E-2 13 372
33 GO:0060485 mesenchyme development 6.835E-6 7.015E-4 6.107E-3 2.315E-2 11 265
34 GO:0043200 response to amino acid 7.206E-6 7.178E-4 6.248E-3 2.441E-2 8 129
35 GO:0035272 exocrine system development 7.465E-6 7.224E-4 6.288E-3 2.528E-2 6 61
36 GO:0010632 regulation of epithelial cell migration 8.810E-6 7.895E-4 6.873E-3 2.984E-2 9 175
37 GO:0061550 cranial ganglion development 8.858E-6 7.895E-4 6.873E-3 3.000E-2 3 6
38 GO:0021825 substrate-dependent cerebral cortex tangential migration 8.858E-6 7.895E-4 6.873E-3 3.000E-2 3 6
39 GO:0030324 lung development 1.002E-5 8.706E-4 7.579E-3 3.395E-2 10 225
40 GO:0007265 Ras protein signal transduction 1.118E-5 9.174E-4 7.986E-3 3.787E-2 12 334
41 GO:0034504 protein localization to nucleus 1.122E-5 9.174E-4 7.986E-3 3.799E-2 13 392
42 GO:0030323 respiratory tube development 1.169E-5 9.174E-4 7.986E-3 3.959E-2 10 229
43 GO:0050673 epithelial cell proliferation 1.184E-5 9.174E-4 7.986E-3 4.010E-2 13 394
44 GO:0032350 regulation of hormone metabolic process 1.192E-5 9.174E-4 7.986E-3 4.036E-2 5 39
45 GO:0071560 cellular response to transforming growth factor beta stimulus 1.261E-5 9.490E-4 8.261E-3 4.270E-2 10 231
46 GO:0048146 positive regulation of fibroblast proliferation 1.408E-5 9.912E-4 8.629E-3 4.768E-2 6 68
47 GO:0048145 regulation of fibroblast proliferation 1.414E-5 9.912E-4 8.629E-3 4.790E-2 7 102
48 GO:0014031 mesenchymal cell development 1.437E-5 9.912E-4 8.629E-3 4.869E-2 9 186
49 GO:0010631 epithelial cell migration 1.463E-5 9.912E-4 8.629E-3 4.956E-2 10 235
50 GO:0071559 response to transforming growth factor beta 1.463E-5 9.912E-4 8.629E-3 4.956E-2 10 235
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 257 annotations before applied cutoff / 19172 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0031012 extracellular matrix 5.082E-13 1.306E-10 8.004E-10 1.306E-10 23 444
2 GO:0005578 proteinaceous extracellular matrix 1.108E-10 1.423E-8 8.723E-8 2.847E-8 19 379
3 GO:0044420 extracellular matrix component 1.141E-9 9.773E-8 5.989E-7 2.932E-7 12 143
4 GO:0034774 secretory granule lumen 3.038E-7 1.952E-5 1.196E-4 7.808E-5 8 85
5 GO:0060205 cytoplasmic vesicle lumen 1.437E-6 7.028E-5 4.307E-4 3.694E-4 8 104
6 GO:0031091 platelet alpha granule 1.813E-6 7.028E-5 4.307E-4 4.660E-4 7 75
7 GO:0031983 vesicle lumen 1.914E-6 7.028E-5 4.307E-4 4.919E-4 8 108
8 GO:0031093 platelet alpha granule lumen 4.058E-6 1.304E-4 7.989E-4 1.043E-3 6 55
9 GO:0005604 basement membrane 2.462E-5 6.922E-4 4.242E-3 6.328E-3 7 111
10 GO:0005605 basal lamina 2.693E-5 6.922E-4 4.242E-3 6.922E-3 4 23
11 GO:0005583 fibrillar collagen trimer 9.424E-5 2.018E-3 1.237E-2 2.422E-2 3 12
12 GO:0098643 banded collagen fibril 9.424E-5 2.018E-3 1.237E-2 2.422E-2 3 12
13 GO:0072562 blood microparticle 1.234E-4 2.440E-3 1.495E-2 3.172E-2 7 143
14 GO:0005606 laminin-1 complex 1.767E-4 3.027E-3 1.855E-2 4.541E-2 2 3
15 GO:0043259 laminin-10 complex 1.767E-4 3.027E-3 1.855E-2 4.541E-2 2 3
16 GO:0005788 endoplasmic reticulum lumen 2.089E-4 3.355E-3 2.056E-2
5.368E-2
 8 207
17 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex 3.516E-4 5.019E-3 3.076E-2
9.035E-2
 2 4
18 GO:0071953 elastic fiber 3.516E-4 5.019E-3 3.076E-2
9.035E-2
 2 4
19 GO:0098644 complex of collagen trimers 7.128E-4 9.641E-3
5.908E-2
1.832E-1
 3 23
20 GO:0030141 secretory granule 1.129E-3 1.451E-2
8.890E-2
2.901E-1
 10 401
21 GO:0043256 laminin complex 1.608E-3 1.967E-2
1.206E-1
4.132E-1
 2 8
22 GO:0005577 fibrinogen complex 2.056E-3 2.202E-2
1.350E-1
5.285E-1
 2 9
23 GO:0008091 spectrin 2.056E-3 2.202E-2
1.350E-1
5.285E-1
 2 9
24 GO:0042583 chromaffin granule 2.056E-3 2.202E-2
1.350E-1
5.285E-1
 2 9
25 GO:0001527 microfibril 2.558E-3 2.629E-2
1.611E-1
6.573E-1
 2 10
26 GO:0031252 cell leading edge 3.281E-3 3.243E-2
1.988E-1
8.433E-1
 9 389
27 GO:0005925 focal adhesion 3.509E-3 3.340E-2
2.047E-1
9.019E-1
 9 393
28 GO:0005924 cell-substrate adherens junction 3.812E-3 3.416E-2
2.093E-1
9.796E-1
 9 398
29 GO:0044798 nuclear transcription factor complex 3.855E-3 3.416E-2
2.093E-1
9.906E-1
 5 134
30 GO:0030055 cell-substrate junction 4.134E-3 3.536E-2
2.167E-1
1.000E0
 9 403
31 GO:0031092 platelet alpha granule membrane 4.366E-3 3.536E-2
2.167E-1
1.000E0
 2 13
32 GO:0005912 adherens junction 4.403E-3 3.536E-2
2.167E-1
1.000E0
 10 484
33 GO:0005581 collagen trimer 4.815E-3 3.750E-2
2.298E-1
1.000E0
 4 88
Show 28 more annotations

4: Human Phenotype [Display Chart] 631 annotations before applied cutoff / 4410 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 2942 annotations before applied cutoff / 9299 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0002989 small kidney 1.849E-7 5.441E-4 4.660E-3 5.441E-4 15 240
2 MP:0003942 abnormal urinary system development 1.351E-6 1.988E-3 1.702E-2 3.975E-3 11 145
3 MP:0006208 lethality throughout fetal growth and development 8.098E-6 7.942E-3
6.802E-2
 2.383E-2 19 500
4 MP:0011101 prenatal lethality, incomplete penetrance 1.209E-5 8.894E-3
7.617E-2
 3.558E-2 17 422
5 MP:0002706 abnormal kidney size 1.643E-5 9.669E-3
8.281E-2
 4.835E-2 15 344
6 MP:0005023 abnormal wound healing 3.104E-5 1.522E-2
1.304E-1
9.132E-2
 11 201
7 MP:0011109 lethality throughout fetal growth and development, incomplete penetrance 3.692E-5 1.552E-2
1.329E-1
1.086E-1
 12 243
8 MP:0000163 abnormal cartilage morphology 5.392E-5 1.930E-2
1.652E-1
1.586E-1
 15 381
9 MP:0001238 thin epidermis stratum spinosum 5.903E-5 1.930E-2
1.652E-1
1.737E-1
 3 7
10 MP:0000527 abnormal kidney development 7.001E-5 2.060E-2
1.764E-1
2.060E-1
 8 114
11 MP:0011091 prenatal lethality, complete penetrance 7.891E-5 2.110E-2
1.807E-1
2.321E-1
 15 394
12 MP:0010182 decreased susceptibility to weight gain 1.021E-4 2.432E-2
2.083E-1
3.003E-1
 9 154
13 MP:0002111 abnormal tail morphology 1.075E-4 2.432E-2
2.083E-1
3.162E-1
 15 405
14 MP:0000520 absent kidney 1.299E-4 2.730E-2
2.338E-1
3.822E-1
 6 65
15 MP:0003122 maternal imprinting 1.532E-4 3.004E-2
2.573E-1
4.506E-1
 4 23
16 MP:0005659 decreased susceptibility to diet-induced obesity 1.760E-4 3.151E-2
2.699E-1
5.176E-1
 8 130
17 MP:0009660 abnormal induced retinal neovascularization 1.821E-4 3.151E-2
2.699E-1
5.357E-1
 4 24
18 MP:0006113 abnormal heart septum morphology 1.960E-4 3.204E-2
2.744E-1
5.767E-1
 14 380
19 MP:0001723 disorganized yolk sac vascular plexus 2.148E-4 3.325E-2
2.848E-1
6.318E-1
 4 25
20 MP:0000534 abnormal ureter morphology 2.466E-4 3.627E-2
3.107E-1
7.255E-1
 9 173
21 MP:0011088 neonatal lethality, incomplete penetrance 2.702E-4 3.785E-2
3.242E-1
7.949E-1
 14 392
22 MP:0001711 abnormal placenta morphology 3.564E-4 4.766E-2
4.082E-1
1.000E0
 13 355
Show 17 more annotations

6: Domain [Display Chart] 1162 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR000299 FERM domain InterPro 2.320E-6 5.073E-4 3.874E-3 2.696E-3 6 49
2 IPR019749 Band 41 domain InterPro 2.620E-6 5.073E-4 3.874E-3 3.044E-3 6 50
3 PS50057 FERM 3 PROSITE 2.620E-6 5.073E-4 3.874E-3 3.044E-3 6 50
4 PS00661 FERM 2 PROSITE 2.620E-6 5.073E-4 3.874E-3 3.044E-3 6 50
5 PS00660 FERM 1 PROSITE 2.620E-6 5.073E-4 3.874E-3 3.044E-3 6 50
6 SM00295 B41 SMART 2.620E-6 5.073E-4 3.874E-3 3.044E-3 6 50
7 PF00373 FERM M Pfam 3.036E-5 4.421E-3 3.375E-2 3.527E-2 5 46
8 PS00022 EGF 1 PROSITE 3.719E-5 4.421E-3 3.375E-2 4.322E-2 10 256
9 IPR019748 FERM central InterPro 4.143E-5 4.421E-3 3.375E-2 4.815E-2 5 49
10 IPR013032 EGF-like CS InterPro 4.523E-5 4.421E-3 3.375E-2
5.255E-2
 10 262
11 IPR014352 FERM/acyl-CoA-bd prot 3-hlx InterPro 4.575E-5 4.421E-3 3.375E-2
5.316E-2
 5 50
12 IPR022350 Insulin-like growth factor InterPro 6.199E-5 4.421E-3 3.375E-2
7.203E-2
 2 2
13 PF00093 VWC Pfam 6.606E-5 4.421E-3 3.375E-2
7.676E-2
 4 28
14 PD002078 Fib collagen C ProDom 7.609E-5 4.421E-3 3.375E-2
8.841E-2
 3 11
15 SM00755 Grip SMART 7.609E-5 4.421E-3 3.375E-2
8.841E-2
 3 11
16 PS51461 NC1 FIB PROSITE 7.609E-5 4.421E-3 3.375E-2
8.841E-2
 3 11
17 IPR000885 Fib collagen C InterPro 7.609E-5 4.421E-3 3.375E-2
8.841E-2
 3 11
18 PF01410 COLFI Pfam 7.609E-5 4.421E-3 3.375E-2
8.841E-2
 3 11
19 PF01465 GRIP Pfam 7.609E-5 4.421E-3 3.375E-2
8.841E-2
 3 11
20 SM00038 COLFI SMART 7.609E-5 4.421E-3 3.375E-2
8.841E-2
 3 11
21 PS50196 RANBD1 PROSITE 1.009E-4 4.884E-3 3.729E-2
1.172E-1
 3 12
22 PS50913 GRIP PROSITE 1.009E-4 4.884E-3 3.729E-2
1.172E-1
 3 12
23 IPR000237 GRIP dom InterPro 1.009E-4 4.884E-3 3.729E-2
1.172E-1
 3 12
24 PF00638 Ran BP1 Pfam 1.009E-4 4.884E-3 3.729E-2
1.172E-1
 3 12
25 SM00181 EGF SMART 1.102E-4 5.121E-3 3.910E-2
1.280E-1
 9 236
26 SM00160 RanBD SMART 1.304E-4 5.611E-3 4.284E-2
1.515E-1
 3 13
27 IPR000156 Ran bind dom InterPro 1.304E-4 5.611E-3 4.284E-2
1.515E-1
 3 13
28 IPR000742 EGF-like dom InterPro 1.701E-4 7.059E-3
5.390E-2
1.977E-1
 9 250
29 PS01208 VWFC 1 PROSITE 1.809E-4 7.250E-3
5.536E-2
2.103E-1
 4 36
30 PS50184 VWFC 2 PROSITE 2.240E-4 8.396E-3
6.410E-2
2.603E-1
 4 38
31 SM00214 VWC SMART 2.240E-4 8.396E-3
6.410E-2
2.603E-1
 4 38
32 IPR009030 Growth fac rcpt InterPro 2.431E-4 8.734E-3
6.669E-2
2.824E-1
 7 156
33 2.120.10.30 - Gene3D 2.481E-4 8.734E-3
6.669E-2
2.882E-1
 4 39
34 PS01186 EGF 2 PROSITE 2.696E-4 9.216E-3
7.037E-2
3.133E-1
 9 266
35 IPR001007 VWF dom InterPro 3.314E-4 1.097E-2
8.373E-2
3.851E-1
 4 42
36 IPR007477 SAB dom InterPro 3.681E-4 1.097E-2
8.373E-2
4.277E-1
 2 4
37 PF05902 4 1 CTD Pfam 3.681E-4 1.097E-2
8.373E-2
4.277E-1
 2 4
38 PF04382 SAB Pfam 3.681E-4 1.097E-2
8.373E-2
4.277E-1
 2 4
39 IPR008379 Band 4.1 C InterPro 3.681E-4 1.097E-2
8.373E-2
4.277E-1
 2 4
40 IPR011042 6-blade b-propeller TolB-like InterPro 4.715E-4 1.370E-2
1.046E-1
5.479E-1
 4 46
41 IPR011993 PH dom-like InterPro 5.921E-4 1.663E-2
1.270E-1
6.881E-1
 11 427
42 1.20.80.10 - Gene3D 6.011E-4 1.663E-2
1.270E-1
6.984E-1
 4 49
43 IPR022352 Insulin family InterPro 9.106E-4 2.461E-2
1.879E-1
1.000E0
 2 6
44 PF12662 cEGF Pfam 1.099E-3 2.777E-2
2.120E-1
1.000E0
 3 26
45 IPR026823 cEGF InterPro 1.099E-3 2.777E-2
2.120E-1
1.000E0
 3 26
46 PF09380 FERM C Pfam 1.099E-3 2.777E-2
2.120E-1
1.000E0
 3 26
47 IPR018980 FERM PH-like C InterPro 1.229E-3 2.947E-2
2.251E-1
1.000E0
 3 27
48 SM01196 FERM C SMART 1.229E-3 2.947E-2
2.251E-1
1.000E0
 3 27
49 PF16704 Rab bind Pfam 1.268E-3 2.947E-2
2.251E-1
1.000E0
 2 7
50 IPR032023 GCC2 Rab bind InterPro 1.268E-3 2.947E-2
2.251E-1
1.000E0
 2 7
Show 45 more annotations

7: Pathway [Display Chart] 798 annotations before applied cutoff / 10916 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M5884 Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans MSigDB C2 BIOCARTA (v5.1) 1.084E-8 8.648E-6 6.278E-5 8.648E-6 16 275
2 576262 Extracellular matrix organization BioSystems: REACTOME 4.463E-8 1.781E-5 1.293E-4 3.561E-5 15 264
3 M3008 Genes encoding structural ECM glycoproteins MSigDB C2 BIOCARTA (v5.1) 4.956E-7 1.318E-4 9.570E-4 3.955E-4 12 196
4 198795 Focal Adhesion BioSystems: WikiPathways 1.930E-6 3.851E-4 2.796E-3 1.540E-3 11 184
5 83067 Focal adhesion BioSystems: KEGG 5.768E-6 9.206E-4 6.683E-3 4.603E-3 11 206
6 692234 PI3K-Akt signaling pathway BioSystems: KEGG 7.475E-6 9.942E-4 7.218E-3 5.965E-3 14 346
7 198766 Inflammatory Response Pathway BioSystems: WikiPathways 1.406E-5 1.603E-3 1.164E-2 1.122E-2 5 32
8 198780 Senescence and Autophagy BioSystems: WikiPathways 8.833E-5 8.806E-3
6.393E-2
7.049E-2
 7 107
9 167324 Amoebiasis BioSystems: KEGG 9.932E-5 8.806E-3
6.393E-2
7.926E-2
 7 109
10 198880 Complement and Coagulation Cascades BioSystems: WikiPathways 1.413E-4 1.108E-2
8.044E-2
1.127E-1
 5 51
11 198871 Id Signaling Pathway BioSystems: WikiPathways 1.551E-4 1.108E-2
8.044E-2
1.238E-1
 5 52
12 106050 Platelet degranulation BioSystems: REACTOME 1.893E-4 1.108E-2
8.044E-2
1.511E-1
 6 85
13 PW:0000238 insulin-like growth factor signaling Pathway Ontology 1.942E-4 1.108E-2
8.044E-2
1.550E-1
 3 12
14 83068 ECM-receptor interaction BioSystems: KEGG 2.019E-4 1.108E-2
8.044E-2
1.611E-1
 6 86
15 477129 Developmental Biology BioSystems: REACTOME 2.433E-4 1.108E-2
8.044E-2
1.942E-1
 13 419
16 P00034 Integrin signalling pathway PantherDB 2.439E-4 1.108E-2
8.044E-2
1.947E-1
 8 167
17 M4470 Extrinsic Prothrombin Activation Pathway MSigDB C2 BIOCARTA (v5.1) 2.506E-4 1.108E-2
8.044E-2
2.000E-1
 3 13
18 106048 Response to elevated platelet cytosolic Ca2+ BioSystems: REACTOME 2.590E-4 1.108E-2
8.044E-2
2.067E-1
 6 90
19 106034 Platelet activation, signaling and aggregation BioSystems: REACTOME 2.638E-4 1.108E-2
8.044E-2
2.105E-1
 9 214
20 161026 Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) BioSystems: REACTOME 2.891E-4 1.153E-2
8.374E-2
2.307E-1
 2 3
21 P00033 Insulin/IGF pathway-protein kinase B signaling cascade PantherDB 3.344E-4 1.249E-2
9.067E-2
2.668E-1
 4 34
22 106028 Hemostasis BioSystems: REACTOME 3.443E-4 1.249E-2
9.067E-2
2.748E-1
 14 493
23 523016 Transcriptional misregulation in cancer BioSystems: KEGG 3.900E-4 1.353E-2
9.823E-2
3.112E-1
 8 179
24 198812 Endochondral Ossification BioSystems: WikiPathways 4.779E-4 1.589E-2
1.154E-1
3.814E-1
 5 66
25 83073 Complement and coagulation cascades BioSystems: KEGG 5.871E-4 1.874E-2
1.360E-1
4.685E-1
 5 69
26 P00011 Blood coagulation PantherDB 6.296E-4 1.932E-2
1.403E-1
5.024E-1
 4 40
27 730347 SHC-related events triggered by IGF1R BioSystems: REACTOME 6.897E-4 2.039E-2
1.480E-1
5.504E-1
 3 18
28 749777 Hippo signaling pathway BioSystems: KEGG 8.228E-4 2.345E-2
1.702E-1
6.566E-1
 7 154
29 M3005 Genes encoding collagen proteins MSigDB C2 BIOCARTA (v5.1) 9.072E-4 2.496E-2
1.812E-1
7.240E-1
 4 44
30 106058 Extrinsic Pathway BioSystems: REACTOME 9.512E-4 2.530E-2
1.837E-1
7.590E-1
 2 5
31 906029 Laminin interactions BioSystems: REACTOME 1.444E-3 3.717E-2
2.699E-1
1.000E0
 3 23
32 83065 Axon guidance BioSystems: KEGG 1.602E-3 3.962E-2
2.877E-1
1.000E0
 6 127
33 PW:0000015 Alzheimer disease Pathway Ontology 1.639E-3 3.962E-2
2.877E-1
1.000E0
 3 24
34 576263 Degradation of the extracellular matrix BioSystems: REACTOME 1.855E-3 4.354E-2
3.161E-1
1.000E0
 5 89
35 833812 ECM proteoglycans BioSystems: REACTOME 2.097E-3 4.782E-2
3.472E-1
1.000E0
 4 55
Show 30 more annotations

8: Pubmed [Display Chart] 27300 annotations before applied cutoff / 51853 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 20673868:gr A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). GeneRIF 1.619E-14 1.184E-10 1.278E-9 4.419E-10 13 187
2 20673868 A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). Pubmed 1.619E-14 1.184E-10 1.278E-9 4.419E-10 13 187
3 20452482 Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. Pubmed 1.735E-14 1.184E-10 1.278E-9 4.736E-10 13 188
4 20452482:gr Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. GeneRIF 1.735E-14 1.184E-10 1.278E-9 4.736E-10 13 188
5 20551380 Proteomics characterization of extracellular space components in the human aorta. Pubmed 5.306E-13 2.897E-9 3.127E-8 1.449E-8 10 101
6 21362503 Protein profile of exosomes from trabecular meshwork cells. Pubmed 1.843E-12 8.387E-9 9.051E-8 5.032E-8 8 49
7 11311202 Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53. Pubmed 1.683E-9 4.912E-6 5.301E-5 4.595E-5 5 18
8 19453261:gr High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. GeneRIF 1.786E-9 4.912E-6 5.301E-5 4.877E-5 12 383
9 19453261 High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Pubmed 1.786E-9 4.912E-6 5.301E-5 4.877E-5 12 383
10 14718574 The human plasma proteome: a nonredundant list developed by combination of four separate sources. Pubmed 1.799E-9 4.912E-6 5.301E-5 4.912E-5 9 166
11 11891225 Laminin-10/11 and fibronectin differentially prevent apoptosis induced by serum removal via phosphatidylinositol 3-kinase/Akt- and MEK1/ERK-dependent pathways. Pubmed 2.467E-9 5.612E-6 6.056E-5 6.734E-5 4 7
12 11891225:gr Laminin-10/11 and fibronectin differentially prevent apoptosis induced by serum removal via phosphatidylinositol 3-kinase/Akt- and MEK1/ERK-dependent pathways. GeneRIF 2.467E-9 5.612E-6 6.056E-5 6.734E-5 4 7
13 20140262 Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth. Pubmed 3.930E-9 7.664E-6 8.271E-5 1.073E-4 7 79
14 20140262:gr Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth. GeneRIF 3.930E-9 7.664E-6 8.271E-5 1.073E-4 7 79
15 16335952 Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. Pubmed 5.432E-9 9.887E-6 1.067E-4 1.483E-4 10 257
16 19625176 PTEN identified as important risk factor of chronic obstructive pulmonary disease. Pubmed 1.752E-8 2.325E-5 2.509E-4 4.782E-4 11 376
17 19625176:gr PTEN identified as important risk factor of chronic obstructive pulmonary disease. GeneRIF 1.752E-8 2.325E-5 2.509E-4 4.782E-4 11 376
18 19578796:gr Association of genetic variants with chronic kidney disease in individuals with different lipid profiles. GeneRIF 1.857E-8 2.325E-5 2.509E-4 5.070E-4 8 152
19 19578796 Association of genetic variants with chronic kidney disease in individuals with different lipid profiles. Pubmed 1.857E-8 2.325E-5 2.509E-4 5.070E-4 8 152
20 19170196 Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. Pubmed 2.114E-8 2.325E-5 2.509E-4 5.772E-4 11 383
21 19170196:gr Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. GeneRIF 2.114E-8 2.325E-5 2.509E-4 5.772E-4 11 383
22 22372631 Does insulin-like growth factor 1 receptor (IGF-1R) targeting provide new treatment options for chordomas? A retrospective clinical and immunohistochemical study. Pubmed 2.470E-8 2.325E-5 2.509E-4 6.742E-4 3 3
23 9278415 The self-association and fibronectin-binding sites of fibulin-1 map to calcium-binding epidermal growth factor-like domains. Pubmed 2.470E-8 2.325E-5 2.509E-4 6.742E-4 3 3
24 15954927:gr Skeletal muscle mRNA for IGF-IEa, IGF-II, and IGF-I receptor is decreased in sedentary chronic hemodialysis patients. GeneRIF 2.470E-8 2.325E-5 2.509E-4 6.742E-4 3 3
25 23306204:gr SOX9 regulates low density lipoprotein receptor-related protein 6 (LRP6) and T-cell factor 4 (TCF4) expression and Wnt/Ã?-catenin activation in breast cancer. GeneRIF 2.470E-8 2.325E-5 2.509E-4 6.742E-4 3 3
26 15954927 Skeletal muscle mRNA for IGF-IEa, IGF-II, and IGF-I receptor is decreased in sedentary chronic hemodialysis patients. Pubmed 2.470E-8 2.325E-5 2.509E-4 6.742E-4 3 3
27 22372631:gr Does insulin-like growth factor 1 receptor (IGF-1R) targeting provide new treatment options for chordomas? A retrospective clinical and immunohistochemical study. GeneRIF 2.470E-8 2.325E-5 2.509E-4 6.742E-4 3 3
28 21251749:gr Association between endometriosis and polymorphisms in insulin-like growth factors (IGFs) and IGF-I receptor genes in Korean women. GeneRIF 2.470E-8 2.325E-5 2.509E-4 6.742E-4 3 3
29 21251749 Association between endometriosis and polymorphisms in insulin-like growth factors (IGFs) and IGF-I receptor genes in Korean women. Pubmed 2.470E-8 2.325E-5 2.509E-4 6.742E-4 3 3
30 19692168 Genetic susceptibility to distinct bladder cancer subphenotypes. Pubmed 5.650E-8 4.975E-5 5.369E-4 1.542E-3 11 422
31 19692168:gr Genetic susceptibility to distinct bladder cancer subphenotypes. GeneRIF 5.650E-8 4.975E-5 5.369E-4 1.542E-3 11 422
32 23658023 Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance. Pubmed 8.317E-8 5.850E-5 6.313E-4 2.270E-3 6 73
33 23395167 LRP6 enhances glucose metabolism by promoting TCF7L2-dependent insulin receptor expression and IGF receptor stabilization in humans. Pubmed 9.857E-8 5.850E-5 6.313E-4 2.691E-3 3 4
34 18349294:gr Risk of testicular germ cell tumors and polymorphisms in the insulin-like growth factor genes. GeneRIF 9.857E-8 5.850E-5 6.313E-4 2.691E-3 3 4
35 15181035:gr Association of the polycystic ovary syndrome with genomic variants related to insulin resistance, type 2 diabetes mellitus, and obesity. GeneRIF 9.857E-8 5.850E-5 6.313E-4 2.691E-3 3 4
36 24956249 No association between genetic or epigenetic variation in insulin growth factors and antipsychotic-induced metabolic disturbances in a cross-sectional sample. Pubmed 9.857E-8 5.850E-5 6.313E-4 2.691E-3 3 4
37 18349294 Risk of testicular germ cell tumors and polymorphisms in the insulin-like growth factor genes. Pubmed 9.857E-8 5.850E-5 6.313E-4 2.691E-3 3 4
38 23395167:gr LRP6 enhances glucose metabolism by promoting TCF7L2-dependent insulin receptor expression and IGF receptor stabilization in humans. GeneRIF 9.857E-8 5.850E-5 6.313E-4 2.691E-3 3 4
39 12127559:gr Expression of insulin-like growth factors IGF-I and IGF-II, and their receptors during the growth and megakaryocytic differentiation of K562 cells. GeneRIF 9.857E-8 5.850E-5 6.313E-4 2.691E-3 3 4
40 26760116 Low Oxygen Tension Modulates the Insulin-Like Growth Factor-1 or -2 Signaling via Both Insulin-Like Growth Factor-1 Receptor and Insulin Receptor to Maintain Stem Cell Identity in Placental Mesenchymal Stem Cells. Pubmed 9.857E-8 5.850E-5 6.313E-4 2.691E-3 3 4
41 15205474:gr Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR. GeneRIF 9.857E-8 5.850E-5 6.313E-4 2.691E-3 3 4
42 15205474 Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR. Pubmed 9.857E-8 5.850E-5 6.313E-4 2.691E-3 3 4
43 1409674 Activation of expression of genes coding for extracellular matrix proteins in Tat-producing glioblastoma cells. Pubmed 9.857E-8 5.850E-5 6.313E-4 2.691E-3 3 4
44 15181035 Association of the polycystic ovary syndrome with genomic variants related to insulin resistance, type 2 diabetes mellitus, and obesity. Pubmed 9.857E-8 5.850E-5 6.313E-4 2.691E-3 3 4
45 12127559 Expression of insulin-like growth factors IGF-I and IGF-II, and their receptors during the growth and megakaryocytic differentiation of K562 cells. Pubmed 9.857E-8 5.850E-5 6.313E-4 2.691E-3 3 4
46 18676006:gr Immunolocalization of insulin-like growth factors and their receptors in the diabetic mouse oviduct and uterine tissues during the preimplantation period. GeneRIF 9.857E-8 5.850E-5 6.313E-4 2.691E-3 3 4
47 24804215 Extracellular matrix proteins expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line. Pubmed 1.257E-7 7.299E-5 7.877E-4 3.431E-3 4 16
48 18676680 Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. Pubmed 2.168E-7 1.100E-4 1.188E-3 5.919E-3 10 381
49 18676680:gr Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. GeneRIF 2.168E-7 1.100E-4 1.188E-3 5.919E-3 10 381
50 22516433 Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. Pubmed 2.202E-7 1.100E-4 1.188E-3 6.011E-3 7 141
Show 45 more annotations

9: Interaction [Display Chart] 3207 annotations before applied cutoff / 16534 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:NOV NOV interactions 5.275E-7 1.692E-3 1.463E-2 1.692E-3 5 19
2 int:PDGFB PDGFB interactions 1.169E-6 1.875E-3 1.622E-2 3.751E-3 5 22
3 int:SMAD2 SMAD2 interactions 2.173E-6 2.322E-3 2.009E-2 6.967E-3 13 295
4 int:MYOC MYOC interactions 2.994E-6 2.401E-3 2.077E-2 9.603E-3 6 46
5 int:ITGAV ITGAV interactions 3.866E-6 2.480E-3 2.145E-2 1.240E-2 6 48
6 int:PDGFA PDGFA interactions 9.778E-6 5.226E-3 4.521E-2 3.136E-2 4 16
7 int:IGFBP5 IGFBP5 interactions 2.040E-5 8.953E-3
7.745E-2
6.542E-2
 4 19
8 int:COL13A1 COL13A1 interactions 2.300E-5 8.953E-3
7.745E-2
7.377E-2
 3 7
9 int:PLG PLG interactions 2.513E-5 8.953E-3
7.745E-2
8.058E-2
 6 66
10 int:NID1 NID1 interactions 6.389E-5 1.774E-2
1.535E-1
2.049E-1
 4 25
11 int:SPARC SPARC interactions 6.389E-5 1.774E-2
1.535E-1
2.049E-1
 4 25
12 int:ITGB3 ITGB3 interactions 7.713E-5 1.774E-2
1.535E-1
2.474E-1
 5 50
13 int:ANTXR2 ANTXR2 interactions 7.735E-5 1.774E-2
1.535E-1
2.481E-1
 3 10
14 int:SEMA3D SEMA3D interactions 7.744E-5 1.774E-2
1.535E-1
2.484E-1
 2 2
15 int:TGFBI TGFBI interactions 1.057E-4 2.259E-2
1.954E-1
3.389E-1
 3 11
16 int:SMAD3 SMAD3 interactions 1.159E-4 2.324E-2
2.010E-1
3.718E-1
 12 372
17 int:IGFBP3 IGFBP3 interactions 1.337E-4 2.523E-2
2.182E-1
4.289E-1
 4 30
18 int:PTPRK PTPRK interactions 1.734E-4 3.090E-2
2.673E-1
5.561E-1
 6 93
19 int:PLAT PLAT interactions 1.956E-4 3.302E-2
2.856E-1
6.274E-1
 4 33
20 int:AMBP AMBP interactions 2.286E-4 3.666E-2
3.171E-1
7.332E-1
 3 14
21 int:SRI SRI interactions 2.759E-4 4.213E-2
3.645E-1
8.848E-1
 4 36
22 int:ACTA1 ACTA1 interactions 3.412E-4 4.974E-2
4.302E-1
1.000E0
 8 195
Show 17 more annotations

10: Cytoband [Display Chart] 131 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1p22-p21 1p22-p21 1.869E-4 2.400E-2
1.309E-1
 2.449E-2 2 5
2 12p12.3 12p12.3 3.664E-4 2.400E-2
1.309E-1
 4.800E-2 3 32
3 7q21 7q21 1.425E-3 4.756E-2
2.595E-1
1.867E-1
 2 13
4 2q32 2q32 1.658E-3 4.756E-2
2.595E-1
2.172E-1
 2 14
5 11q14.2 11q14.2 2.174E-3 4.756E-2
2.595E-1
2.847E-1
 2 16
6 6q23 6q23 2.456E-3 4.756E-2
2.595E-1
3.218E-1
 2 17
7 12q14.2 12q14.2 3.071E-3 4.756E-2
2.595E-1
4.023E-1
 2 19
8 2q13 2q13 3.730E-3 4.756E-2
2.595E-1
4.886E-1
 3 71
9 3q23-q24 3q23-q24 4.356E-3 4.756E-2
2.595E-1
5.707E-1
 1 1
10 10q26.13-q26.3 10q26.13-q26.3 4.356E-3 4.756E-2
2.595E-1
5.707E-1
 1 1
11 3p12-q12 3p12-q12 4.356E-3 4.756E-2
2.595E-1
5.707E-1
 1 1
12 2q14-q32 2q14-q32 4.356E-3 4.756E-2
2.595E-1
5.707E-1
 1 1
Show 7 more annotations

11: Transcription Factor Binding Site [Display Chart] 499 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GCTNWTTGK UNKNOWN GCTNWTTGK UNKNOWN 1.321E-5 6.594E-3 4.478E-2 6.594E-3 12 248
2 V$PAX2 02 V$PAX2 02 7.048E-5 1.351E-2
9.176E-2
 3.517E-2 10 206
3 V$FAC1 01 V$FAC1 01 8.124E-5 1.351E-2
9.176E-2
 4.054E-2 9 169
4 V$OCT1 02 V$OCT1 02 1.433E-4 1.783E-2
1.211E-1
7.149E-2
 9 182
5 V$IRF Q6 V$IRF Q6 1.831E-4 1.783E-2
1.211E-1
9.135E-2
 9 188
6 V$SOX9 B1 V$SOX9 B1 2.144E-4 1.783E-2
1.211E-1
1.070E-1
 9 192
7 CATTGTYY V$SOX9 B1 CATTGTYY V$SOX9 B1 2.975E-4 2.121E-2
1.440E-1
1.484E-1
 11 293
8 V$CDX2 Q5 V$CDX2 Q5 3.488E-4 2.176E-2
1.478E-1
1.741E-1
 9 205
9 V$SOX5 01 V$SOX5 01 4.462E-4 2.474E-2
1.680E-1
2.226E-1
 9 212
10 V$ETS2 B V$ETS2 B 5.837E-4 2.913E-2
1.978E-1
2.913E-1
 9 220
11 WTGAAAT UNKNOWN WTGAAAT UNKNOWN 8.180E-4 3.711E-2
2.520E-1
4.082E-1
 14 496
Show 6 more annotations

12: Gene Family [Display Chart] 85 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1293 Minor histocompatibility antigens|FERM domain containing genenames.org 7.897E-6 6.713E-4 3.374E-3 6.713E-4 5 50
2 490 Collagens genenames.org 1.174E-4 4.991E-3 2.508E-2 9.982E-3 4 46
3 951 Erythrocyte membrane protein band 4.1|FERM domain containing genenames.org 1.782E-4 5.048E-3 2.537E-2 1.514E-2 2 4
4 626 Laminin subunits genenames.org 1.904E-3 4.047E-2
2.034E-1
1.619E-1
 2 12

13: Coexpression [Display Chart] 6302 annotations before applied cutoff / 21867 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M13206 Genes down-regulated in TC71 and EWS502 cells (Ewing's sarcoma) by EWSR1-FLI1 [GeneID=2130;2314] as inferred from RNAi knockdown of this fusion protein. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.119E-20 1.335E-16 1.245E-15 1.335E-16 26 326
2 M15981 Genes up-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.776E-18 5.597E-15 5.220E-14 1.119E-14 27 430
3 M2001 Genes associated with migration rate of 40 human bladder cancer cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.123E-17 6.561E-14 6.119E-13 1.968E-13 19 184
4 M17471 Genes up-regulated in invasive ductal carcinoma (IDC) relative to ductal carcinoma in situ (DCIS, non-invasive). MSigDB C2: CGP Curated Gene Sets (v5.1) 3.521E-15 5.010E-12 4.672E-11 2.219E-11 22 351
5 M12225 Up-regulated genes in angioimmunoblastic lymphoma (AILT) compared to normal T lymphocytes. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.975E-15 5.010E-12 4.672E-11 2.505E-11 18 205
6 M4995 Genes specifically up-regulated in Cluster IIb of urothelial cell carcinom (UCC) tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.068E-14 3.222E-11 3.005E-10 1.933E-10 22 390
7 M7396 Genes down-regulated in the Kras2LA mouse lung cancer model with mutated KRAS [GeneID=3845]. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.796E-13 2.517E-10 2.347E-9 1.762E-9 22 435
8 M9192 Genes down-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.541E-13 6.728E-10 6.275E-9 5.383E-9 22 460
9 M3645 Genes up-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.491E-12 2.444E-9 2.280E-8 2.200E-8 21 443
10 M1804 Genes up-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [GeneID=6605] off a retroviral vector. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.673E-12 6.096E-9 5.685E-8 6.096E-8 17 280
11 M17923 Genes up-regulated in cultured stromal stem cells from adipose tissue, compared to the freshly isolated cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.358E-11 7.782E-9 7.257E-8 8.560E-8 20 425
12 M1834 Genes up-regulated in freshly isolated CD31- [GeneID=5175] (stromal stem cells from adipose tissue) versus the CD31+ (non-stem) counterparts. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.331E-11 1.709E-8 1.594E-7 2.099E-7 16 260
13 M10253 Genes down-regulated in NIH3T3 cells (fibroblasts) after treatment with Y27632 [PubChem=123862], an inhibitor of ROCK proteins; the changes did not depend on expression of constitutively active (Q63L) form of RHOA [GeneID=387]. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.525E-11 1.709E-8 1.594E-7 2.221E-7 9 48
14 M3804 Genes up-regulated in normal hematopoietic progenitors by RUNX1-RUNX1T1 [GeneID=861;862] fusion. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.855E-11 1.735E-8 1.618E-7 2.430E-7 14 185
15 M988 Genes up-regulated in T98G cells (glioblastoma) by TNC [GeneID=3371]. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.622E-11 1.942E-8 1.811E-7 2.913E-7 13 153
16 M4680 Genes up-regulated in RD cells (embryonal rhabdomyosarcoma, ERMS) by expression of PAX3- or PAX7-FOXO1 [GeneID=5077;5081;2308] fusions off retroviral vectors. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.659E-10 1.047E-7 9.769E-7 1.676E-6 15 255
17 M2502 Genes whose expression changes in Calu-6 cells (lung cancer) by TNF [GeneID=7124] were blocked partially by p38 inhibitor LY479754. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.123E-9 4.163E-7 3.882E-6 7.077E-6 12 160
18 M14555 Down-regulated at any timepoint following infection of primary human foreskin fibroblasts with CMV MSigDB C2: CGP Curated Gene Sets (v5.1) 1.338E-9 4.684E-7 4.369E-6 8.432E-6 11 128
19 M9639 Genes up-regulated in MDA-MB-231 cells (breast cancer) after knockdown of SATB1 [GeneID=6304] by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.993E-9 6.610E-7 6.164E-6 1.256E-5 17 395
20 M1124 Pubertal genes up-regulated by TGFB1 [GeneID=7040]. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.102E-9 6.625E-7 6.178E-6 1.325E-5 12 169
21 M13867 Genes up-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.771E-9 8.317E-7 7.756E-6 1.747E-5 14 256
22 M9128 Genes up-regulated in UB27 cells (osteosarcoma) at any time point after inducing the expression of a mutant form of WT1 [GeneID=7490]. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.955E-9 8.464E-7 7.894E-6 1.862E-5 13 214
23 M17079 Up-regulated genes distinguishing between two subtypes of gastric cancer: advanced (AGC) and early (EGC). MSigDB C2: CGP Curated Gene Sets (v5.1) 3.129E-9 8.573E-7 7.995E-6 1.972E-5 12 175
24 M5944 Genes up-regulated during formation of blood vessels (angiogenesis). MSigDB H: Hallmark Gene Sets (v5.1) 4.387E-9 1.152E-6 1.074E-5 2.765E-5 7 36
25 M5942 Genes down-regulated in response to ultraviolet (UV) radiation. MSigDB H: Hallmark Gene Sets (v5.1) 4.681E-9 1.180E-6 1.101E-5 2.950E-5 11 144
26 M8519 Genes down-regulated in mARMS (molecular ARMS) compared to the mERMS (molecular ERMS) class of rhabdomyosarcoma tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.882E-9 1.183E-6 1.103E-5 3.076E-5 12 182
27 M4737 ECM related genes up-regulated early (within 30 min) in dermal fibroblasts after addition of TGFB1 [GeneID=7040]. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.827E-9 1.360E-6 1.268E-5 3.672E-5 8 58
28 M2259 Partial list of genes up-regulated in the kidney of GLIS2 [GeneID=84662] knockout mice compared to the wild type. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.276E-9 1.412E-6 1.317E-5 3.955E-5 9 84
29 M5311 Genes from 'subtype S1' signature of hepatocellular carcinoma (HCC): aberrant activation of the WNT signaling pathway. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.010E-8 2.192E-6 2.044E-5 6.366E-5 13 237
30 M16975 Up-regulated genes in peripheral zone of human pancreatic cancer growing in the pancreas of nude mice compared to that of the tumor from the central zone. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.043E-8 2.192E-6 2.044E-5 6.576E-5 14 284
31 M178 Tumorigenesis markers of head and neck squamous cell carcinoma (HNSCC): up-regulated in the 'early' tumors vs normal samples. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.144E-8 2.325E-6 2.168E-5 7.208E-5 8 63
32 M17163 Genes up-regulated at early fetal liver stage (embryonic days E11.5 - E12.5) compared to the late fetal liver stage (embryonic days E14.5 - E16.5). MSigDB C2: CGP Curated Gene Sets (v5.1) 2.074E-8 4.084E-6 3.809E-5 1.307E-4 11 166
33 M10165 Genes up-regulated in lobular carcinoma vs normal ductal breast cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.385E-8 4.555E-6 4.248E-5 1.503E-4 8 69
34 M2255 Genes commonly up-regulated in UET-13 cells (mesenchymal progenitor) by expression of EWSR1 [GeneID=2130] fusions with ETS transcription factors FLI1 and ERG [GeneID=2313 ,2078]. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.899E-8 5.373E-6 5.011E-5 1.827E-4 13 259
35 M3955 Integrin, VEGF, Wnt and TGFbeta signaling pathway genes up-regulated in PC-3 cells (prostate cancer) after knockdown of PDEF [GeneID=25803] by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.000E-8 5.402E-6 5.038E-5 1.891E-4 8 71
36 M18149 Genes up-regulated in peripheral blood monocytes by HGF [GeneID=3082]. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.164E-8 5.539E-6 5.165E-5 1.994E-4 16 418
37 M15835 Genes down-regulated SUM44/LCCTam cells (breast cancer) resistant to 4-hydroxytamoxifen [PubChem=63062] relative to the parental SUM44 cells sensitive to the drug. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.060E-8 6.915E-6 6.449E-5 2.559E-4 12 220
38 M4913 Genes down-regulated in adipose tissue mesenchymal stem cells (ASC) vs bone marrow mesenchymal stem cells (rBMSC) MSigDB C2: CGP Curated Gene Sets (v5.1) 5.800E-8 9.618E-6 8.970E-5 3.655E-4 9 108
39 M2726 Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] MCF-7 cells (breast cancer) stably over-expressing constitutively active RAF1 [Gene ID=5894] gene. MSigDB C6: Oncogenic Signatures (v5.1) 1.028E-7 1.661E-5 1.549E-4 6.478E-4 11 194
40 GSE21774 CD62L POS CD56 BRIGHT VS CD62L NEG CD56 DIM NK CELL UP Genes up-regulated in NCAM1+ SELL bright [GeneID=4684;6402] versus NCAM1- SELL dim [GeneID=4684;6402]. MSigDB C7: Immunologic Signatures (v5.1) 1.400E-7 2.100E-5 1.959E-4 8.821E-4 11 200
41 M4612 Genes down-regulated in comparison of CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 10 versus CD25- T cells treated with IL4 [GeneID=3565] at 10 h. MSigDB C7: Immunologic Signatures (v5.1) 1.400E-7 2.100E-5 1.959E-4 8.821E-4 11 200
42 GSE43955 1H VS 20H ACT CD4 TCELL WITH TGFB IL6 DN Genes down-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 1h versus 20h. MSigDB C7: Immunologic Signatures (v5.1) 1.400E-7 2.100E-5 1.959E-4 8.821E-4 11 200
43 M12828 Genes up-regulated in reverted NIH3T3 cells (fibroblasts transformed by activated KRAS [GeneID=3845] which then reverted to normal cells upon stable over-expression of a dominant negative form of CDC25 [GeneID=5923]) vs normal fibroblasts. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.446E-7 2.119E-5 1.976E-4 9.113E-4 9 120
44 M16026 Cluster 1: ECM related genes up-regulated in dermal fibroblasts within 30 min after TGFB1 [GeneID=7040] addition, and which kept increasing with time. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.529E-7 2.189E-5 2.042E-4 9.633E-4 5 19
45 M8510 Top down-regulated marker genes for medulloblastoma classification: desmoplastic vs classic morphology. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.572E-7 2.201E-5 2.052E-4 9.904E-4 7 59
46 M10184 Genes up-regulated in monocytes by RUNX1-RUNX1T1 [GeneID=861;862] fusion. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.710E-7 2.342E-5 2.184E-4 1.077E-3 11 204
47 M14601 Genes up-regulated in hepatoblastoma samples compared to normal liver tissue. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.981E-7 2.656E-5 2.477E-4 1.248E-3 11 207
48 M2122 Genes correlated with mesenchymal type of glioblastoma multiforme tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.036E-7 3.986E-5 3.717E-4 1.913E-3 11 216
49 M6746 Genes up-regulated in cells from Flt3L Melanom injected mice: 33D1+ versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v5.1) 3.162E-7 4.067E-5 3.793E-4 1.993E-3 10 172
50 M16774 Genes down-regulated in primary cultures of ovarian surface epithlium cells exposed to progesterone [PubChem=5994] for 5 days. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.447E-7 4.344E-5 4.051E-4 2.172E-3 7 66
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 3268 annotations before applied cutoff / 20974 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GSM777043 500 Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3 Immgen.org, GSE15907 3.170E-24 1.036E-20 8.982E-20 1.036E-20 33 445
2 54Dn Top 500 All 54Dn Top 500 All Brain Map - Allen iN 8.061E-23 9.357E-20 8.112E-19 2.634E-19 33 493
3 80Dn Top 500 All 80Dn Top 500 All Brain Map - Allen iN 8.590E-23 9.357E-20 8.112E-19 2.807E-19 33 494
4 54Dn SubClass 54Dn 1SK Top 500 All 54Dn SubClass 54Dn 1SK Top 500 All Brain Map - Allen iN 1.297E-22 1.059E-19 9.184E-19 4.237E-19 32 461
5 GSM777067 500 Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2 Immgen.org, GSE15907 1.238E-20 8.092E-18 7.016E-17 4.046E-17 30 453
6 endothelial Top 500 All endothelial Top 500 All Brain Map - Barres 1.745E-18 9.084E-16 7.875E-15 5.704E-15 29 496
7 26Dn SubClass 26Dn 2 Top 500 All 26Dn SubClass 26Dn 2 Top 500 All Brain Map - Allen iN 1.946E-18 9.084E-16 7.875E-15 6.359E-15 29 498
8 GSM777055 500 Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4 Immgen.org, GSE15907 2.078E-17 8.490E-15 7.360E-14 6.792E-14 27 455
9 GSM777059 500 Stromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 9.382E-16 3.407E-13 2.953E-12 3.066E-12 25 439
10 GSM777063 500 Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 1.662E-15 5.431E-13 4.709E-12 5.431E-12 25 450
11 gudmap dev gonad e11.5 M GonadVasMes Flk 500 dev gonad e11.5 M GonadVasMes Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 3.277E-15 9.737E-13 8.441E-12 1.071E-11 24 419
12 GSM777050 500 Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5 Immgen.org, GSE15907 3.899E-15 1.062E-12 9.206E-12 1.274E-11 25 467
13 gudmap dev gonad e11.5 F GonadVasMes Flk 500 dev gonad e11.5 F GonadVasMes Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 4.265E-15 1.072E-12 9.295E-12 1.394E-11 24 424
14 GSM777037 500 Stromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 2.453E-14 5.725E-12 4.963E-11 8.015E-11 24 459
15 GSM777046 500 Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4 Immgen.org, GSE15907 8.183E-14 1.783E-11 1.546E-10 2.674E-10 23 438
16 endothelial SubClass DCN-hi Top 500 All endothelial SubClass DCN-hi Top 500 All Brain Map - Barres 1.271E-13 2.597E-11 2.251E-10 4.155E-10 24 495
17 GSM777032 500 Stromal Cells, BEC.MLN, gp38- CD31+, Lymph Node, avg-5 Immgen.org, GSE15907 1.902E-13 3.657E-11 3.170E-10 6.216E-10 23 456
18 gudmap kidney adult Mesangium Meis 500 kidney adult Mesangium Meis top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 4.796E-13 8.707E-11 7.548E-10 1.567E-9 22 429
19 26Dn Top 500 All 26Dn Top 500 All Brain Map - Allen iN 1.087E-12 1.870E-10 1.621E-9 3.554E-9 23 496
20 54Dn Top 500 Cluster 0 54Dn Top 500 Cluster 0 Brain Map - Allen iN 1.219E-12 1.916E-10 1.661E-9 3.985E-9 14 138
21 PCBC ratio EB vs SC 500 ratio EmbryoidBody vs StemCell top-relative-expression-ranked 500 PCBC 1.231E-12 1.916E-10 1.661E-9 4.023E-9 23 499
22 80Dn Top 500 Cluster 1 80Dn Top 500 Cluster 1 Brain Map - Allen iN 2.547E-12 3.783E-10 3.280E-9 8.323E-9 12 92
23 GSM777043 100 Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3 Immgen.org, GSE15907 4.853E-12 6.896E-10 5.978E-9 1.586E-8 12 97
24 54Dn SubClass 54Dn 1SK Top 500 Cluster 2 54Dn SubClass 54Dn 1SK Top 500 Cluster 2 Brain Map - Allen iN 7.685E-12 1.046E-9 9.072E-9 2.511E-8 17 265
25 gudmap dev gonad e13.5 F VascAssocMesenchStromOvary MafB 500 dev gonad e13.5 F VascAssocMesenchStromOvary MafB top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.166E-11 1.524E-9 1.322E-8 3.811E-8 19 358
26 gudmap dev gonad e12.5 M InterstitTestis Sma 500 dev gonad e12.5 M InterstitTestis Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 2.483E-11 3.120E-9 2.705E-8 8.113E-8 19 374
27 ratio EB vs SC 1000 K1 ratio EmbryoidBody vs StemCell top-relative-expression-ranked 1000 k-means-cluster#1 PCBC 3.610E-11 4.370E-9 3.788E-8 1.180E-7 18 336
28 80Dn SubClass 80Dn 1 Top 500 Cluster 0 80Dn SubClass 80Dn 1 Top 500 Cluster 0 Brain Map - Allen iN 4.787E-11 5.394E-9 4.677E-8 1.564E-7 21 489
29 80Dn SubClass 80Dn 1 Top 500 All 80Dn SubClass 80Dn 1 Top 500 All Brain Map - Allen iN 4.787E-11 5.394E-9 4.677E-8 1.564E-7 21 489
30 gudmap dev gonad e12.5 F gudmap devVasOvary Flk k1 1000 dev gonad e12.5 F DevVasOvary Flk k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 7.649E-11 8.332E-9 7.223E-8 2.500E-7 14 187
31 gudmap dev gonad e11.5 F ReproVasc Flk 500 dev gonad e11.5 F ReproVasc Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.146E-10 1.208E-8 1.047E-7 3.745E-7 19 409
32 gudmap dev gonad e12.5 M InterstitLeydig MafB 500 dev gonad e12.5 M InterstitLeydig MafB top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.335E-10 1.335E-8 1.158E-7 4.363E-7 18 364
33 JC fibro 1000 K1 JC fibro top-relative-expression-ranked 1000 k-means-cluster#1 PCBC 1.348E-10 1.335E-8 1.158E-7 4.406E-7 20 464
34 gudmap dev gonad e12.5 M gudmap devVasTestis Flk 500 dev gonad e12.5 M DevVasTestis Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.408E-10 1.353E-8 1.173E-7 4.601E-7 19 414
35 gudmap dev gonad e12.5 F gudmap devVasOvary Flk 500 dev gonad e12.5 F DevVasOvary Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.467E-10 1.369E-8 1.187E-7 4.793E-7 19 415
36 gudmap developingLowerUrinaryTract e14.5 Genital tubercle 1000 k2 DevelopingLowerUrinaryTract e14.5 Genital tubercle emap-6706 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 2.356E-10 2.139E-8 1.854E-7 7.701E-7 18 377
37 gudmap dev gonad e13.5 F VascAssocMesenchStromOvary Sma k4 1000 dev gonad e13.5 F VascAssocMesenchStromOvary Sma k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 2.479E-10 2.190E-8 1.898E-7 8.102E-7 13 168
38 endothelial Top 500 Cluster 4 endothelial Top 500 Cluster 4 Brain Map - Barres 5.507E-10 4.736E-8 4.106E-7 1.800E-6 15 258
39 26Dn SubClass 26Dn 2 Top 500 Cluster 2 26Dn SubClass 26Dn 2 Top 500 Cluster 2 Brain Map - Allen iN 5.739E-10 4.809E-8 4.169E-7 1.876E-6 12 145
40 GSM791122 500 Fetal Liver, SC.STSL.FL, IgM- CD24- CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Fetal Liver, avg-2 Immgen.org, GSE15907 9.041E-10 7.386E-8 6.403E-7 2.955E-6 18 410
41 GSM538239 500 Myeloid Cells, DC.103-11b+.Lv, CD45+ CD11c+ MHC-II + CD11b high CD103-, Liver, avg-3 Immgen.org, GSE15907 9.398E-10 7.491E-8 6.494E-7 3.071E-6 18 411
42 GSM854271 500 Myeloid Cells, DC.103-11b+24-.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24-, Lung, avg-2 Immgen.org, GSE15907 1.055E-9 8.208E-8 7.116E-7 3.447E-6 18 414
43 gudmap dev gonad e13.5 F gudmap devVascOvary Flk 500 dev gonad e13.5 F DevVascOvary Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.139E-9 8.654E-8 7.503E-7 3.721E-6 18 416
44 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 500 dev lower uro neuro e15.5 PelvicGanglion Sox10 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.495E-9 1.111E-7 9.628E-7 4.887E-6 17 372
45 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 k2 500 dev lower uro neuro e15.5 PelvicGanglion Sox10 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.891E-9 1.373E-7 1.190E-6 6.179E-6 11 127
46 gudmap dev gonad e13.5 M InterstitFLeydig MafB 500 dev gonad e13.5 M InterstitFLeydig MafB top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 5.921E-9 4.206E-7 3.647E-6 1.935E-5 16 356
47 gudmap dev gonad e11.5 M ReproVasc Flk 500 dev gonad e11.5 M ReproVasc Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 7.421E-9 5.107E-7 4.428E-6 2.425E-5 17 414
48 gudmap dev gonad e13.5 M InterstitTestis Sma 500 dev gonad e13.5 M InterstitTestis Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 7.502E-9 5.107E-7 4.428E-6 2.452E-5 16 362
49 Lungmap Mouse e16.5 Matrix fibroblast Top 500 All Mouse Lung E16.5 Matrix Fibroblast top 500 Lungmap Mouse Single Cell (Lungmap.net) 9.182E-9 6.124E-7 5.309E-6 3.001E-5 17 420
50 ratio EB vs SC 500 K5 ratio EmbryoidBody vs StemCell top-relative-expression-ranked 500 k-means-cluster#5 PCBC 1.105E-8 7.220E-7 6.260E-6 3.610E-5 10 116
Show 45 more annotations

15: Computational [Display Chart] 364 annotations before applied cutoff / 9399 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GNF2 CDH11 Neighborhood of CDH11 MSigDb: C4 - CGN: Cancer Gene Neighborhood 1.712E-10 6.231E-8 4.035E-7 6.231E-8 8 25
2 module 47 Genes in module 47 MSigDb: C4 - CM: Cancer Modules 1.786E-9 3.250E-7 2.104E-6 6.499E-7 16 216
3 module 2 Genes in module 2 MSigDb: C4 - CM: Cancer Modules 5.076E-9 6.159E-7 3.989E-6 1.848E-6 20 378
4 module 12 Genes in module 12 MSigDb: C4 - CM: Cancer Modules 8.946E-9 8.141E-7 5.272E-6 3.256E-6 19 351
5 module 52 Genes in module 52 MSigDb: C4 - CM: Cancer Modules 2.904E-8 2.114E-6 1.369E-5 1.057E-5 20 419
6 module 1 Genes in module 1 MSigDb: C4 - CM: Cancer Modules 8.167E-8 4.954E-6 3.208E-5 2.973E-5 18 361
7 GNF2 PTX3 Neighborhood of PTX3 MSigDb: C4 - CGN: Cancer Gene Neighborhood 1.135E-7 5.904E-6 3.823E-5 4.133E-5 7 36
8 module 5 Genes in module 5 MSigDb: C4 - CM: Cancer Modules 1.767E-7 8.039E-6 5.206E-5 6.431E-5 19 423
9 module 3 Genes in module 3 MSigDb: C4 - CM: Cancer Modules 7.521E-7 3.042E-5 1.970E-4 2.738E-4 17 375
10 module 513 Genes in module 513 MSigDb: C4 - CM: Cancer Modules 9.947E-7 3.621E-5 2.345E-4 3.621E-4 4 8
11 module 38 Genes in module 38 MSigDb: C4 - CM: Cancer Modules 2.453E-6 8.119E-5 5.258E-4 8.931E-4 18 455
12 module 122 Genes in module 122 MSigDb: C4 - CM: Cancer Modules 2.958E-6 8.973E-5 5.811E-4 1.077E-3 10 138
13 module 18 Genes in module 18 MSigDb: C4 - CM: Cancer Modules 5.884E-6 1.648E-4 1.067E-3 2.142E-3 17 436
14 module 118 Genes in module 118 MSigDb: C4 - CM: Cancer Modules 7.071E-6 1.838E-4 1.191E-3 2.574E-3 16 395
15 module 105 Genes in module 105 MSigDb: C4 - CM: Cancer Modules 1.002E-5 2.431E-4 1.575E-3 3.647E-3 11 194
16 module 234 Genes in module 234 MSigDb: C4 - CM: Cancer Modules 2.525E-5 5.745E-4 3.720E-3 9.192E-3 6 53
17 module 6 Genes in module 6 MSigDb: C4 - CM: Cancer Modules 4.258E-5 9.117E-4 5.904E-3 1.550E-2 15 407
18 module 400 Genes in module 400 MSigDb: C4 - CM: Cancer Modules 5.010E-5 1.013E-3 6.561E-3 1.824E-2 4 19
19 module 220 Genes in module 220 MSigDb: C4 - CM: Cancer Modules 6.926E-5 1.327E-3 8.592E-3 2.521E-2 13 328
20 module 324 Genes in module 324 MSigDb: C4 - CM: Cancer Modules 1.032E-4 1.878E-3 1.216E-2 3.756E-2 8 131
21 module 60 Genes in module 60 MSigDb: C4 - CM: Cancer Modules 1.760E-4 3.051E-3 1.976E-2
6.408E-2
 14 410
22 module 176 Genes in module 176 MSigDb: C4 - CM: Cancer Modules 2.150E-4 3.558E-3 2.304E-2
7.827E-2
 10 227
23 module 75 Genes in module 75 MSigDb: C4 - CM: Cancer Modules 3.943E-4 6.187E-3 4.006E-2
1.435E-1
 13 391
24 module 24 Genes in module 24 MSigDb: C4 - CM: Cancer Modules 4.079E-4 6.187E-3 4.006E-2
1.485E-1
 14 445
25 module 112 Genes in module 112 MSigDb: C4 - CM: Cancer Modules 5.773E-4 8.405E-3
5.443E-2
2.101E-1
 10 257
26 module 19 Genes in module 19 MSigDb: C4 - CM: Cancer Modules 6.104E-4 8.546E-3
5.534E-2
2.222E-1
 11 307
27 module 401 Genes in module 401 MSigDb: C4 - CM: Cancer Modules 6.825E-4 9.201E-3
5.959E-2
2.484E-1
 3 16
28 module 121 Genes in module 121 MSigDb: C4 - CM: Cancer Modules 7.721E-4 1.004E-2
6.500E-2
2.810E-1
 6 98
29 module 46 Genes in module 46 MSigDb: C4 - CM: Cancer Modules 1.200E-3 1.506E-2
9.752E-2
4.367E-1
 12 386
30 module 209 Genes in module 209 MSigDb: C4 - CM: Cancer Modules 2.690E-3 3.264E-2
2.114E-1
9.792E-1
 5 86
31 module 44 Genes in module 44 MSigDb: C4 - CM: Cancer Modules 2.926E-3 3.436E-2
2.225E-1
1.000E0
 10 319
32 module 382 Genes in module 382 MSigDb: C4 - CM: Cancer Modules 3.623E-3 4.121E-2
2.669E-1
1.000E0
 3 28
33 module 524 Genes in module 524 MSigDb: C4 - CM: Cancer Modules 4.418E-3 4.873E-2
3.156E-1
1.000E0
 3 30
34 module 128 Genes in module 128 MSigDb: C4 - CM: Cancer Modules 4.722E-3 4.914E-2
3.182E-1
1.000E0
 5 98
35 module 223 Genes in module 223 MSigDb: C4 - CM: Cancer Modules 4.725E-3 4.914E-2
3.182E-1
1.000E0
 6 140
Show 30 more annotations

16: MicroRNA [Display Chart] 1348 annotations before applied cutoff / 19844 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-539:PITA hsa-miR-539:PITA TOP PITA 1.924E-12 2.594E-9 2.019E-8 2.594E-9 23 483
2 hsa-miR-145:PITA hsa-miR-145:PITA TOP PITA 2.644E-11 1.782E-8 1.387E-7 3.564E-8 20 401
3 hsa-miR-767-5p:PITA hsa-miR-767-5p:PITA TOP PITA 4.076E-11 1.832E-8 1.426E-7 5.495E-8 17 279
4 hsa-miR-376a:PITA hsa-miR-376a:PITA TOP PITA 5.520E-9 1.488E-6 1.158E-5 7.440E-6 13 205
5 hsa-miR-376b:PITA hsa-miR-376b:PITA TOP PITA 5.520E-9 1.488E-6 1.158E-5 7.440E-6 13 205
6 hsa-miR-196b:TargetScan hsa-miR-196b:TargetScan TargetScan 6.912E-8 1.331E-5 1.036E-4 9.318E-5 12 210
7 hsa-miR-196a:TargetScan hsa-miR-196a:TargetScan TargetScan 6.912E-8 1.331E-5 1.036E-4 9.318E-5 12 210
8 hsa-let-7b:PITA hsa-let-7b:PITA TOP PITA 1.589E-7 1.339E-5 1.042E-4 2.142E-4 15 373
9 hsa-let-7g:PITA hsa-let-7g:PITA TOP PITA 1.589E-7 1.339E-5 1.042E-4 2.142E-4 15 373
10 hsa-let-7f:PITA hsa-let-7f:PITA TOP PITA 1.589E-7 1.339E-5 1.042E-4 2.142E-4 15 373
11 hsa-miR-98:PITA hsa-miR-98:PITA TOP PITA 1.589E-7 1.339E-5 1.042E-4 2.142E-4 15 373
12 hsa-let-7a:PITA hsa-let-7a:PITA TOP PITA 1.589E-7 1.339E-5 1.042E-4 2.142E-4 15 373
13 hsa-let-7e:PITA hsa-let-7e:PITA TOP PITA 1.589E-7 1.339E-5 1.042E-4 2.142E-4 15 373
14 hsa-let-7i:PITA hsa-let-7i:PITA TOP PITA 1.589E-7 1.339E-5 1.042E-4 2.142E-4 15 373
15 hsa-let-7c:PITA hsa-let-7c:PITA TOP PITA 1.589E-7 1.339E-5 1.042E-4 2.142E-4 15 373
16 hsa-let-7d:PITA hsa-let-7d:PITA TOP PITA 1.589E-7 1.339E-5 1.042E-4 2.142E-4 15 373
17 hsa-miR-452:PITA hsa-miR-452:PITA TOP PITA 3.280E-7 2.600E-5 2.024E-4 4.421E-4 16 451
18 hsa-miR-377:PITA hsa-miR-377:PITA TOP PITA 4.146E-7 3.105E-5 2.417E-4 5.589E-4 16 459
19 CTTTGTA,MIR-524:MSigDB CTTTGTA,MIR-524:MSigDB MSigDB 5.147E-7 3.652E-5 2.843E-4 6.939E-4 15 409
20 miR-199a-star:PicTar miR-199a-star:PicTar PicTar 7.630E-7 5.143E-5 4.003E-4 1.029E-3 15 422
21 hsa-miR-641:PITA hsa-miR-641:PITA TOP PITA 9.827E-7 6.308E-5 4.910E-4 1.325E-3 16 490
22 hsa-miR-539:TargetScan hsa-miR-539:TargetScan TargetScan 1.052E-6 6.448E-5 5.019E-4 1.419E-3 15 433
23 miR-141:PicTar miR-141:PicTar PicTar 1.702E-6 9.978E-5 7.767E-4 2.295E-3 13 336
24 hsa-miR-219-2-3p:PITA hsa-miR-219-2-3p:PITA TOP PITA 1.875E-6 1.053E-4 8.196E-4 2.527E-3 10 190
25 let-7d:PicTar let-7d:PicTar PicTar 2.407E-6 1.249E-4 9.720E-4 3.245E-3 15 463
26 miR-206:PicTar miR-206:PicTar PicTar 2.443E-6 1.249E-4 9.720E-4 3.293E-3 14 404
27 hsa-miR-409-3p:PITA hsa-miR-409-3p:PITA TOP PITA 2.501E-6 1.249E-4 9.720E-4 3.372E-3 12 294
28 miR-1:PicTar miR-1:PicTar PicTar 2.739E-6 1.318E-4 1.026E-3 3.692E-3 14 408
29 hsa-miR-26a:PITA hsa-miR-26a:PITA TOP PITA 3.125E-6 1.325E-4 1.031E-3 4.212E-3 15 473
30 hsa-miR-26b:PITA hsa-miR-26b:PITA TOP PITA 3.125E-6 1.325E-4 1.031E-3 4.212E-3 15 473
31 hsa-miR-1297:PITA hsa-miR-1297:PITA TOP PITA 3.125E-6 1.325E-4 1.031E-3 4.212E-3 15 473
32 hsa-miR-29c:miRTarbase hsa-miR-29c:miRTarbase miRTarbase 3.347E-6 1.325E-4 1.031E-3 4.512E-3 5 31
33 hsa-miR-1208:PITA hsa-miR-1208:PITA TOP PITA 3.530E-6 1.325E-4 1.031E-3 4.758E-3 12 304
34 hsa-miR-155:PITA hsa-miR-155:PITA TOP PITA 3.530E-6 1.325E-4 1.031E-3 4.758E-3 12 304
35 hsa-miR-101:PITA hsa-miR-101:PITA TOP PITA 3.642E-6 1.325E-4 1.031E-3 4.909E-3 15 479
36 TGGTGCT,MIR-29A:MSigDB TGGTGCT,MIR-29A:MSigDB MSigDB 3.735E-6 1.325E-4 1.031E-3 5.035E-3 15 480
37 TGGTGCT,MIR-29C:MSigDB TGGTGCT,MIR-29C:MSigDB MSigDB 3.735E-6 1.325E-4 1.031E-3 5.035E-3 15 480
38 TGGTGCT,MIR-29B:MSigDB TGGTGCT,MIR-29B:MSigDB MSigDB 3.735E-6 1.325E-4 1.031E-3 5.035E-3 15 480
39 hsa-miR-29c:miRecords TarBase hsa-miR-29c:miRecords TarBase miRecords_TarBase 4.013E-6 1.387E-4 1.080E-3 5.409E-3 4 15
40 hsa-miR-1284:PITA hsa-miR-1284:PITA TOP PITA 4.628E-6 1.560E-4 1.214E-3 6.239E-3 14 427
41 hsa-miR-516a-3p:PITA hsa-miR-516a-3p:PITA TOP PITA 4.993E-6 1.576E-4 1.227E-3 6.731E-3 10 212
42 miR-101:PicTar miR-101:PicTar PicTar 5.014E-6 1.576E-4 1.227E-3 6.760E-3 14 430
43 hsa-miR-1251:PITA hsa-miR-1251:PITA TOP PITA 5.028E-6 1.576E-4 1.227E-3 6.778E-3 7 89
44 hsa-miR-105:PITA hsa-miR-105:PITA TOP PITA 5.429E-6 1.663E-4 1.295E-3 7.319E-3 14 433
45 hsa-miR-579:PITA hsa-miR-579:PITA TOP PITA 5.722E-6 1.714E-4 1.334E-3 7.714E-3 14 435
46 miR-32:PicTar miR-32:PicTar PicTar 7.223E-6 2.117E-4 1.648E-3 9.737E-3 14 444
47 hsa-miR-1305:PITA hsa-miR-1305:PITA TOP PITA 9.064E-6 2.600E-4 2.024E-3 1.222E-2 14 453
48 hsa-miR-216b:PITA hsa-miR-216b:PITA TOP PITA 1.035E-5 2.788E-4 2.170E-3 1.395E-2 12 338
49 ACATTCC,MIR-1:MSigDB ACATTCC,MIR-1:MSigDB MSigDB 1.055E-5 2.788E-4 2.170E-3 1.422E-2 11 283
50 ACATTCC,MIR-206:MSigDB ACATTCC,MIR-206:MSigDB MSigDB 1.055E-5 2.788E-4 2.170E-3 1.422E-2 11 283
Show 45 more annotations

17: Drug [Display Chart] 21627 annotations before applied cutoff / 22098 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 6817 DN Verteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT HG-U133A Broad Institute CMAP 3.038E-12 6.569E-8 6.936E-7 6.569E-8 14 155
2 CID000104802 Rgd Peptide Stitch 8.033E-12 8.686E-8 9.172E-7 1.737E-7 16 239
3 4652 DN Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; PC3; HT HG-U133A Broad Institute CMAP 3.170E-9 1.222E-5 1.291E-4 6.856E-5 12 177
4 CID000024766 chondroitin sulfate Stitch 3.331E-9 1.222E-5 1.291E-4 7.204E-5 17 413
5 1891 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HG-U133A Broad Institute CMAP 3.602E-9 1.222E-5 1.291E-4 7.789E-5 12 179
6 C488369 dasatinib CTD 3.704E-9 1.222E-5 1.291E-4 8.010E-5 18 472
7 D000069439 Dasatinib CTD 3.957E-9 1.222E-5 1.291E-4 8.557E-5 18 474
8 7074 UP MS-275; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 4.921E-9 1.330E-5 1.405E-4 1.064E-4 12 184
9 3556 DN Verteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT HG-U133A Broad Institute CMAP 1.357E-8 3.260E-5 3.442E-4 2.934E-4 11 161
10 CID000447401 1nmk Stitch 3.097E-8 6.698E-5 7.072E-4 6.698E-4 8 72
11 1951 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HG-U133A Broad Institute CMAP 3.622E-8 7.120E-5 7.518E-4 7.832E-4 11 177
12 6316 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 4.822E-8 8.294E-5 8.758E-4 1.043E-3 11 182
13 5981 UP trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 5.101E-8 8.294E-5 8.758E-4 1.103E-3 11 183
14 4610 DN Doxorubicin hydrochloride [25316-40-9]; Down 200; 6.8uM; PC3; HT HG-U133A Broad Institute CMAP 5.394E-8 8.294E-5 8.758E-4 1.167E-3 11 184
15 CID000115346 Gdrgdsp Stitch 5.753E-8 8.294E-5 8.758E-4 1.244E-3 9 109
16 4457 DN rosiglitazone; Down 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 6.366E-8 8.604E-5 9.085E-4 1.377E-3 11 187
17 CID000054454 simvastatin Stitch 7.173E-8 8.618E-5 9.100E-4 1.551E-3 15 390
18 D017258 Medroxyprogesterone Acetate CTD 7.173E-8 8.618E-5 9.100E-4 1.551E-3 15 390
19 7106 DN GSK-3 Inhibitor IX; Down 200; 0.5uM; PC3; HT HG-U133A Broad Institute CMAP 8.333E-8 9.485E-5 1.001E-3 1.802E-3 11 192
20 D013196 Dihydrotestosterone CTD 1.156E-7 1.250E-4 1.320E-3 2.500E-3 14 348
21 4444 UP SAHA; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 1.953E-7 1.920E-4 2.027E-3 4.224E-3 10 165
22 D001663 Bilirubin CTD 1.953E-7 1.920E-4 2.027E-3 4.224E-3 10 165
23 4458 UP Trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 2.723E-7 2.454E-4 2.591E-3 5.890E-3 10 171
24 7535 DN irinotecan HCl; Down 200; 100uM; PC3; HT HG-U133A Broad Institute CMAP 2.723E-7 2.454E-4 2.591E-3 5.890E-3 10 171
25 7285 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 3.034E-7 2.472E-4 2.610E-3 6.561E-3 10 173
26 C021828 Revalor CTD 3.066E-7 2.472E-4 2.610E-3 6.630E-3 3 3
27 D010656 Phenylephrine CTD 3.146E-7 2.472E-4 2.610E-3 6.804E-3 16 500
28 7530 DN irinotecan HCl; Down 200; 100uM; MCF7; HT HG-U133A Broad Institute CMAP 3.200E-7 2.472E-4 2.610E-3 6.921E-3 10 174
29 D018021 Lithium Chloride CTD 3.568E-7 2.661E-4 2.809E-3 7.716E-3 13 325
30 CID000005711 Y-27632 Stitch 3.906E-7 2.816E-4 2.973E-3 8.447E-3 15 445
31 4184 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 4.159E-7 2.869E-4 3.029E-3 8.994E-3 10 179
32 D014302 Trinitrobenzenesulfonic Acid CTD 4.323E-7 2.869E-4 3.029E-3 9.350E-3 14 388
33 4694 UP Mebendazole [31431-39-7]; Up 200; 13.6uM; MCF7; HT HG-U133A Broad Institute CMAP 4.378E-7 2.869E-4 3.029E-3 9.468E-3 10 180
34 7498 DN irinotecan HCl; Down 200; 100uM; MCF7; HT HG-U133A Broad Institute CMAP 5.098E-7 2.983E-4 3.150E-3 1.102E-2 10 183
35 7084 UP MS-275; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 5.098E-7 2.983E-4 3.150E-3 1.102E-2 10 183
36 D003609 Dactinomycin CTD 5.332E-7 2.983E-4 3.150E-3 1.153E-2 12 282
37 6919 UP scriptaid; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 5.360E-7 2.983E-4 3.150E-3 1.159E-2 10 184
38 6755 DN Mitoxantrone dihydrochloride [70476-82-3]; Down 200; 7.8uM; PC3; HT HG-U133A Broad Institute CMAP 5.360E-7 2.983E-4 3.150E-3 1.159E-2 10 184
39 D006046 Gold CTD 5.379E-7 2.983E-4 3.150E-3 1.163E-2 13 337
40 6709 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 6.218E-7 3.284E-4 3.467E-3 1.345E-2 10 187
41 CID000107775 Rgds Peptide Stitch 6.426E-7 3.284E-4 3.467E-3 1.390E-2 8 106
42 7050 DN lomustine; Down 200; 100uM; PC3; HT HG-U133A Broad Institute CMAP 6.529E-7 3.284E-4 3.467E-3 1.412E-2 10 188
43 2079 DN Dexamethasone acetate [1177-87-3]; Down 200; 9.2uM; PC3; HT HG-U133A Broad Institute CMAP 6.529E-7 3.284E-4 3.467E-3 1.412E-2 10 188
44 1807 UP Imipramine hydrochloride [113-52-0]; Up 200; 12.6uM; PC3; HT HG-U133A Broad Institute CMAP 6.854E-7 3.369E-4 3.557E-3 1.482E-2 10 189
45 1172 DN 15d-PGJ2; Down 200; 10uM; HL60; HT HG-U133A Broad Institute CMAP 7.194E-7 3.457E-4 3.650E-3 1.556E-2 10 190
46 C506614 PD 0325901 CTD 7.415E-7 3.486E-4 3.681E-3 1.604E-2 8 108
47 C070081 fulvestrant CTD 8.415E-7 3.872E-4 4.088E-3 1.820E-2 15 473
48 CID000030956 AC1L1KMJ Stitch 9.106E-7 4.025E-4 4.250E-3 1.969E-2 15 476
49 5109 DN Mefenamic acid [61-68-7]; Down 200; 16.6uM; PC3; HT HG-U133A Broad Institute CMAP 9.119E-7 4.025E-4 4.250E-3 1.972E-2 10 195
50 5066 DN Diethylcarbamazine citrate [1642-54-2]; Down 200; 10.2uM; PC3; HT HG-U133A Broad Institute CMAP 1.001E-6 4.197E-4 4.431E-3 2.164E-2 10 197
Show 45 more annotations

18: Disease [Display Chart] 2214 annotations before applied cutoff / 16150 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 umls:C0027626 Neoplasm Invasiveness DisGeNET Curated 1.623E-6 2.115E-3 1.751E-2 3.593E-3 9 132
2 umls:C0542519 Congenital absence of kidney DisGeNET BeFree 2.194E-6 2.115E-3 1.751E-2 4.859E-3 4 12
3 umls:C0011884 Diabetic Retinopathy DisGeNET Curated 2.866E-6 2.115E-3 1.751E-2 6.345E-3 10 181
4 umls:C0023267 Fibroid Tumor DisGeNET Curated 5.219E-6 2.628E-3 2.176E-2 1.156E-2 12 287
5 umls:C1609433 Congenital absence of kidneys syndrome DisGeNET Curated 5.935E-6 2.628E-3 2.176E-2 1.314E-2 4 15
6 umls:C1709246 Non-Neoplastic Disorder DisGeNET BeFree 7.250E-6 2.675E-3 2.215E-2 1.605E-2 15 461
7 umls:C0035412 Rhabdomyosarcoma DisGeNET Curated 1.020E-5 3.104E-3 2.570E-2 2.259E-2 13 360
8 umls:C0268335 Ehlers-Danlos syndrome type 1 DisGeNET Curated 1.122E-5 3.104E-3 2.570E-2 2.483E-2 3 6
9 umls:C0162810 Cicatrix, Hypertrophic DisGeNET BeFree 1.403E-5 3.450E-3 2.857E-2 3.105E-2 6 63
10 umls:C0042133 Uterine Fibroids DisGeNET Curated 1.768E-5 3.915E-3 3.242E-2 3.915E-2 12 324
11 umls:C1260965 Lipoblastoma DisGeNET Curated 1.951E-5 3.927E-3 3.251E-2 4.319E-2 3 7
12 umls:C0403416 Idiopathic crescentic glomerulonephritis DisGeNET BeFree 2.230E-5 4.114E-3 3.406E-2 4.937E-2 5 41
13 umls:C0878787 Growth failure DisGeNET BeFree 2.514E-5 4.282E-3 3.545E-2
5.566E-2
 5 42
14 umls:C0020456 Hyperglycemia DisGeNET Curated 3.092E-5 4.890E-3 4.049E-2
6.846E-2
 13 400
15 umls:C0000786 Spontaneous abortion DisGeNET Curated 3.372E-5 4.977E-3 4.121E-2
7.466E-2
 7 108
16 umls:C0149721 Left Ventricular Hypertrophy DisGeNET Curated 4.135E-5 5.385E-3 4.459E-2
9.154E-2
 8 152
17 umls:C0024668 Mammary Neoplasms, Experimental DisGeNET Curated 4.135E-5 5.385E-3 4.459E-2
9.154E-2
 8 152
18 umls:C0013336 Dwarfism DisGeNET Curated 5.438E-5 6.687E-3
5.537E-2
1.204E-1
 9 204
19 umls:C0281361 Adenocarcinoma of pancreas DisGeNET BeFree 5.739E-5 6.687E-3
5.537E-2
1.271E-1
 11 309
20 umls:C0151779 Cutaneous Melanoma DisGeNET Curated 6.855E-5 7.574E-3
6.271E-2
1.518E-1
 10 261
21 umls:C0175693 Russell-Silver syndrome DisGeNET Curated 7.184E-5 7.574E-3
6.271E-2
1.591E-1
 5 52
22 umls:C0022548 Keloid DisGeNET Curated 7.711E-5 7.642E-3
6.327E-2
1.707E-1
 8 166
23 umls:C1800706 Idiopathic Pulmonary Fibrosis DisGeNET Curated 8.531E-5 7.642E-3
6.327E-2
1.889E-1
 11 323
24 umls:C0039101 synovial sarcoma DisGeNET Curated 8.742E-5 7.642E-3
6.327E-2
1.935E-1
 8 169
25 umls:C1519670 Tumor Angiogenesis DisGeNET BeFree 8.767E-5 7.642E-3
6.327E-2
1.941E-1
 13 443
26 umls:C0555278 Cerebral metastasis DisGeNET BeFree 8.974E-5 7.642E-3
6.327E-2
1.987E-1
 3 11
27 umls:C0239946 Fibrosis, Liver DisGeNET BeFree 9.516E-5 7.803E-3
6.461E-2
2.107E-1
 11 327
28 umls:C0032000 Pituitary Adenoma DisGeNET BeFree 1.026E-4 8.036E-3
6.654E-2
2.271E-1
 10 274
29 umls:C0494165 Secondary malignant neoplasm of liver DisGeNET BeFree 1.072E-4 8.036E-3
6.654E-2
2.374E-1
 13 452
30 umls:C1368683 Epithelioma DisGeNET BeFree 1.089E-4 8.036E-3
6.654E-2
2.411E-1
 10 276
31 umls:C0497327 Dementia DisGeNET Curated 1.209E-4 8.637E-3
7.151E-2
2.677E-1
 11 336
32 umls:C0085207 Gestational Diabetes DisGeNET Curated 1.408E-4 9.740E-3
8.065E-2
3.117E-1
 8 181
33 umls:C0020459 Hyperinsulinism DisGeNET Curated 1.550E-4 1.014E-2
8.397E-2
3.433E-1
 9 234
34 umls:C0024667 Animal Mammary Neoplasms DisGeNET Curated 1.593E-4 1.014E-2
8.397E-2
3.526E-1
 7 138
35 umls:C0242383 Age related macular degeneration DisGeNET Curated 1.603E-4 1.014E-2
8.397E-2
3.550E-1
 11 347
36 umls:C0035309 Retinal Diseases DisGeNET Curated 1.725E-4 1.059E-2
8.764E-2
3.819E-1
 10 292
37 umls:C0032962 Pregnancy Complications DisGeNET Curated 1.805E-4 1.059E-2
8.764E-2
3.997E-1
 5 63
38 umls:C0031511 Pheochromocytoma DisGeNET Curated 1.817E-4 1.059E-2
8.764E-2
4.022E-1
 9 239
39 umls:C0015544 Failure to Thrive DisGeNET BeFree 1.945E-4 1.078E-2
8.924E-2
4.307E-1
 5 64
40 umls:C0011265 Presenile dementia DisGeNET BeFree 2.033E-4 1.078E-2
8.924E-2
4.501E-1
 10 298
41 umls:C2750451 CORNEAL DYSTROPHY, FUCHS ENDOTHELIAL, 3 DisGeNET Curated 2.069E-4 1.078E-2
8.924E-2
4.582E-1
 2 3
42 umls:C1334620 Malignant Smooth Muscle Neoplasm DisGeNET BeFree 2.069E-4 1.078E-2
8.924E-2
4.582E-1
 2 3
43 umls:C0235833 Congenital diaphragmatic hernia DisGeNET Curated 2.093E-4 1.078E-2
8.924E-2
4.635E-1
 5 65
44 umls:C0154830 Proliferative diabetic retinopathy DisGeNET BeFree 2.250E-4 1.132E-2
9.374E-2
4.981E-1
 5 66
45 umls:C0014474 Ependymoma DisGeNET Curated 2.906E-4 1.430E-2
1.184E-1
6.435E-1
 6 108
46 umls:C0020443 Hypercholesterolemia DisGeNET Curated 3.250E-4 1.564E-2
1.295E-1
7.195E-1
 7 155
47 umls:C2931876 Hirschsprung disease 1 DisGeNET Curated 3.384E-4 1.594E-2
1.320E-1
7.493E-1
 5 72
48 umls:C0086692 Benign Neoplasm DisGeNET BeFree 3.507E-4 1.611E-2
1.334E-1
7.765E-1
 8 207
49 umls:C0206658 Smooth Muscle Tumor DisGeNET Curated 3.565E-4 1.611E-2
1.334E-1
7.893E-1
 3 17
50 umls:C0152136 Low Tension Glaucoma DisGeNET BeFree 4.086E-4 1.787E-2
1.480E-1
9.046E-1
 4 42
Show 45 more annotations