Toppgene analysis for aggregated_1964_log, IC10, negative side

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1: GO: Molecular Function [Display Chart] 237 annotations before applied cutoff / 18819 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0019955 cytokine binding 7.014E-6 1.662E-3 1.005E-2 1.662E-3 5 103
2 GO:0001948 glycoprotein binding 1.477E-5 1.751E-3 1.059E-2 3.501E-3 5 120
3 GO:0005519 cytoskeletal regulatory protein binding 3.972E-5 3.138E-3 1.897E-2 9.413E-3 2 4
4 GO:0019199 transmembrane receptor protein kinase activity 9.178E-5 4.463E-3 2.699E-2 2.175E-2 4 91
5 GO:0015631 tubulin binding 1.078E-4 4.463E-3 2.699E-2 2.555E-2 6 293
6 GO:0004867 serine-type endopeptidase inhibitor activity 1.130E-4 4.463E-3 2.699E-2 2.678E-2 4 96
7 GO:0005114 type II transforming growth factor beta receptor binding 1.841E-4 6.234E-3 3.770E-2 4.363E-2 2 8
8 GO:0008017 microtubule binding 2.303E-4 6.749E-3 4.082E-2
5.459E-2
 5 214
9 GO:0005539 glycosaminoglycan binding 2.563E-4 6.749E-3 4.082E-2
6.074E-2
 5 219
10 GO:0005024 transforming growth factor beta-activated receptor activity 2.949E-4 6.989E-3 4.227E-2
6.989E-2
 2 10
11 GO:0019838 growth factor binding 5.058E-4 1.090E-2
6.591E-2
1.199E-1
 4 142
12 GO:0050431 transforming growth factor beta binding 9.894E-4 1.707E-2
1.032E-1
2.345E-1
 2 18
13 GO:0004866 endopeptidase inhibitor activity 1.014E-3 1.707E-2
1.032E-1
2.403E-1
 4 171
14 GO:0004674 protein serine/threonine kinase activity 1.083E-3 1.707E-2
1.032E-1
2.567E-1
 6 452
15 GO:0005201 extracellular matrix structural constituent 1.100E-3 1.707E-2
1.032E-1
2.607E-1
 3 78
16 GO:0061135 endopeptidase regulator activity 1.152E-3 1.707E-2
1.032E-1
2.730E-1
 4 177
17 GO:0030414 peptidase inhibitor activity 1.226E-3 1.709E-2
1.034E-1
2.905E-1
 4 180
18 GO:0005540 hyaluronic acid binding 1.767E-3 2.204E-2
1.333E-1
4.188E-1
 2 24
19 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1.767E-3 2.204E-2
1.333E-1
4.188E-1
 2 24
20 GO:0004702 signal transducer, downstream of receptor, with serine/threonine kinase activity 2.377E-3 2.614E-2
1.581E-1
5.633E-1
 3 102
21 GO:0033746 histone demethylase activity (H3-R2 specific) 2.604E-3 2.614E-2
1.581E-1
6.171E-1
 1 1
22 GO:0033749 histone demethylase activity (H4-R3 specific) 2.604E-3 2.614E-2
1.581E-1
6.171E-1
 1 1
23 GO:0003979 UDP-glucose 6-dehydrogenase activity 2.604E-3 2.614E-2
1.581E-1
6.171E-1
 1 1
24 GO:0061134 peptidase regulator activity 2.679E-3 2.614E-2
1.581E-1
6.349E-1
 4 223
25 GO:0004709 MAP kinase kinase kinase activity 2.758E-3 2.614E-2
1.581E-1
6.536E-1
 2 30
26 GO:0043394 proteoglycan binding 3.741E-3 3.410E-2
2.062E-1
8.866E-1
 2 35
27 GO:1901681 sulfur compound binding 4.632E-3 3.976E-2
2.405E-1
1.000E0
 4 260
28 GO:0008307 structural constituent of muscle 5.104E-3 3.976E-2
2.405E-1
1.000E0
 2 41
29 GO:0035403 histone kinase activity (H3-T6 specific) 5.201E-3 3.976E-2
2.405E-1
1.000E0
 1 2
30 GO:0008147 structural constituent of bone 5.201E-3 3.976E-2
2.405E-1
1.000E0
 1 2
31 GO:0050436 microfibril binding 5.201E-3 3.976E-2
2.405E-1
1.000E0
 1 2
32 GO:0031625 ubiquitin protein ligase binding 5.500E-3 4.073E-2
2.463E-1
1.000E0
 4 273
33 GO:0044389 ubiquitin-like protein ligase binding 5.787E-3 4.156E-2
2.513E-1
1.000E0
 4 277
Show 28 more annotations

2: GO: Biological Process [Display Chart] 1864 annotations before applied cutoff / 18785 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0030198 extracellular matrix organization 2.616E-8 2.504E-5 2.030E-4 4.877E-5 10 354
2 GO:0043062 extracellular structure organization 2.687E-8 2.504E-5 2.030E-4 5.008E-5 10 355
3 GO:0010810 regulation of cell-substrate adhesion 5.810E-7 3.610E-4 2.927E-3 1.083E-3 7 186
4 GO:0007160 cell-matrix adhesion 1.154E-6 5.376E-4 4.359E-3 2.150E-3 7 206
5 GO:0031589 cell-substrate adhesion 2.053E-6 7.655E-4 6.207E-3 3.828E-3 8 324
6 GO:0001952 regulation of cell-matrix adhesion 5.542E-6 1.722E-3 1.396E-2 1.033E-2 5 96
7 GO:0061448 connective tissue development 6.579E-6 1.752E-3 1.420E-2 1.226E-2 7 268
8 GO:0051216 cartilage development 1.373E-5 3.199E-3 2.594E-2 2.560E-2 6 198
9 GO:0048705 skeletal system morphogenesis 3.607E-5 7.469E-3
6.056E-2
6.723E-2
 6 235
10 GO:0014909 smooth muscle cell migration 5.479E-5 1.021E-2
8.281E-2
1.021E-1
 4 78
11 GO:0001654 eye development 7.649E-5 1.296E-2
1.051E-1
1.426E-1
 7 393
12 GO:0001503 ossification 9.374E-5 1.375E-2
1.115E-1
1.747E-1
 7 406
13 GO:0014812 muscle cell migration 9.587E-5 1.375E-2
1.115E-1
1.787E-1
 4 90
14 GO:0001822 kidney development 1.221E-4 1.613E-2
1.308E-1
2.276E-1
 6 293
15 GO:0048754 branching morphogenesis of an epithelial tube 1.298E-4 1.613E-2
1.308E-1
2.420E-1
 5 185
16 GO:0048704 embryonic skeletal system morphogenesis 1.679E-4 1.852E-2
1.502E-1
3.129E-1
 4 104
17 GO:0072001 renal system development 1.689E-4 1.852E-2
1.502E-1
3.149E-1
 6 311
18 GO:0043010 camera-type eye development 2.776E-4 2.800E-2
2.270E-1
5.174E-1
 6 341
19 GO:0061138 morphogenesis of a branching epithelium 3.029E-4 2.800E-2
2.270E-1
5.645E-1
 5 222
20 GO:0048701 embryonic cranial skeleton morphogenesis 3.377E-4 2.800E-2
2.270E-1
6.295E-1
 3 51
21 GO:0001655 urogenital system development 3.599E-4 2.800E-2
2.270E-1
6.709E-1
 6 358
22 GO:0071560 cellular response to transforming growth factor beta stimulus 3.635E-4 2.800E-2
2.270E-1
6.776E-1
 5 231
23 GO:0010631 epithelial cell migration 3.932E-4 2.800E-2
2.270E-1
7.330E-1
 5 235
24 GO:0071559 response to transforming growth factor beta 3.932E-4 2.800E-2
2.270E-1
7.330E-1
 5 235
25 GO:0045861 negative regulation of proteolysis 4.048E-4 2.800E-2
2.270E-1
7.545E-1
 6 366
26 GO:0001763 morphogenesis of a branching structure 4.167E-4 2.800E-2
2.270E-1
7.768E-1
 5 238
27 GO:0090132 epithelium migration 4.167E-4 2.800E-2
2.270E-1
7.768E-1
 5 238
28 GO:0010812 negative regulation of cell-substrate adhesion 4.453E-4 2.800E-2
2.270E-1
8.301E-1
 3 56
29 GO:0090130 tissue migration 4.669E-4 2.800E-2
2.270E-1
8.702E-1
 5 244
30 GO:0000186 activation of MAPKK activity 4.692E-4 2.800E-2
2.270E-1
8.746E-1
 3 57
31 GO:0010951 negative regulation of endopeptidase activity 4.756E-4 2.800E-2
2.270E-1
8.866E-1
 5 245
32 GO:0048706 embryonic skeletal system development 4.807E-4 2.800E-2
2.270E-1
8.961E-1
 4 137
33 GO:0010466 negative regulation of peptidase activity 5.910E-4 3.294E-2
2.671E-1
1.000E0
 5 257
34 GO:1904888 cranial skeletal system development 6.008E-4 3.294E-2
2.671E-1
1.000E0
 3 62
35 GO:0061029 eyelid development in camera-type eye 7.131E-4 3.736E-2
3.029E-1
1.000E0
 2 15
36 GO:0043462 regulation of ATPase activity 7.215E-4 3.736E-2
3.029E-1
1.000E0
 3 66
37 GO:0048146 positive regulation of fibroblast proliferation 7.873E-4 3.908E-2
3.168E-1
1.000E0
 3 68
38 GO:0035239 tube morphogenesis 8.032E-4 3.908E-2
3.168E-1
1.000E0
 6 417
39 GO:0051346 negative regulation of hydrolase activity 8.234E-4 3.908E-2
3.168E-1
1.000E0
 6 419
40 GO:0001938 positive regulation of endothelial cell proliferation 8.928E-4 3.908E-2
3.168E-1
1.000E0
 3 71
41 GO:0042063 gliogenesis 8.975E-4 3.908E-2
3.168E-1
1.000E0
 5 282
42 GO:0021783 preganglionic parasympathetic fiber development 9.205E-4 3.908E-2
3.168E-1
1.000E0
 2 17
43 GO:0048708 astrocyte differentiation 9.299E-4 3.908E-2
3.168E-1
1.000E0
 3 72
44 GO:0014910 regulation of smooth muscle cell migration 9.299E-4 3.908E-2
3.168E-1
1.000E0
 3 72
45 GO:0043542 endothelial cell migration 9.434E-4 3.908E-2
3.168E-1
1.000E0
 4 164
46 GO:0051589 negative regulation of neurotransmitter transport 1.034E-3 4.189E-2
3.396E-1
1.000E0
 2 18
47 GO:0030500 regulation of bone mineralization 1.088E-3 4.261E-2
3.455E-1
1.000E0
 3 76
48 GO:0001558 regulation of cell growth 1.124E-3 4.261E-2
3.455E-1
1.000E0
 6 445
49 GO:0030335 positive regulation of cell migration 1.137E-3 4.261E-2
3.455E-1
1.000E0
 6 446
50 GO:0014912 negative regulation of smooth muscle cell migration 1.153E-3 4.261E-2
3.455E-1
1.000E0
 2 19
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 185 annotations before applied cutoff / 19172 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0031012 extracellular matrix 6.163E-12 1.140E-9 6.613E-9 1.140E-9 14 444
2 GO:0005578 proteinaceous extracellular matrix 3.657E-9 3.383E-7 1.962E-6 6.765E-7 11 379
3 GO:0014069 postsynaptic density 3.025E-6 1.399E-4 8.115E-4 5.596E-4 7 238
4 GO:0099572 postsynaptic specialization 3.025E-6 1.399E-4 8.115E-4 5.596E-4 7 238
5 GO:0060076 excitatory synapse 5.147E-6 1.904E-4 1.105E-3 9.522E-4 7 258
6 GO:0045177 apical part of cell 1.614E-5 4.976E-4 2.886E-3 2.985E-3 8 429
7 GO:0016323 basolateral plasma membrane 4.559E-5 1.205E-3 6.989E-3 8.435E-3 6 245
8 GO:0005925 focal adhesion 7.672E-5 1.661E-3 9.633E-3 1.419E-2 7 393
9 GO:0005924 cell-substrate adherens junction 8.304E-5 1.661E-3 9.633E-3 1.536E-2 7 398
10 GO:0030055 cell-substrate junction 8.977E-5 1.661E-3 9.633E-3 1.661E-2 7 403
11 GO:0098794 postsynapse 1.876E-4 2.992E-3 1.736E-2 3.470E-2 7 454
12 GO:0031983 vesicle lumen 1.941E-4 2.992E-3 1.736E-2 3.591E-2 4 108
13 GO:0042583 chromaffin granule 2.468E-4 3.418E-3 1.982E-2 4.566E-2 2 9
14 GO:0016324 apical plasma membrane 2.609E-4 3.418E-3 1.982E-2 4.827E-2 6 337
15 GO:0005912 adherens junction 2.771E-4 3.418E-3 1.982E-2
5.127E-2
 7 484
16 GO:0044420 extracellular matrix component 5.649E-4 6.532E-3 3.789E-2
1.045E-1
 4 143
17 GO:0034774 secretory granule lumen 1.502E-3 1.635E-2
9.482E-2
2.779E-1
 3 85
18 GO:0015629 actin cytoskeleton 1.621E-3 1.666E-2
9.663E-2
2.999E-1
 6 478
19 GO:0045121 membrane raft 2.130E-3 1.971E-2
1.143E-1
3.941E-1
 5 343
20 GO:0098857 membrane microdomain 2.130E-3 1.971E-2
1.143E-1
3.941E-1
 5 343
21 GO:0031941 filamentous actin 2.334E-3 2.056E-2
1.192E-1
4.317E-1
 2 27
22 GO:0097489 multivesicular body, internal vesicle lumen 2.660E-3 2.061E-2
1.195E-1
4.921E-1
 1 1
23 GO:0038045 large latent transforming growth factor-beta complex 2.660E-3 2.061E-2
1.195E-1
4.921E-1
 1 1
24 GO:0060205 cytoplasmic vesicle lumen 2.673E-3 2.061E-2
1.195E-1
4.945E-1
 3 104
25 GO:0031252 cell leading edge 3.660E-3 2.709E-2
1.571E-1
6.772E-1
 5 389
26 GO:0097442 CA3 pyramidal cell dendrite 5.313E-3 3.390E-2
1.966E-1
9.830E-1
 1 2
27 GO:0070435 Shc-EGFR complex 5.313E-3 3.390E-2
1.966E-1
9.830E-1
 1 2
28 GO:0035692 macrophage migration inhibitory factor receptor complex 5.313E-3 3.390E-2
1.966E-1
9.830E-1
 1 2
29 GO:0031673 H zone 5.313E-3 3.390E-2
1.966E-1
9.830E-1
 1 2
30 GO:0042383 sarcolemma 7.843E-3 4.331E-2
2.512E-1
1.000E0
 3 153
31 GO:0060053 neurofilament cytoskeleton 7.960E-3 4.331E-2
2.512E-1
1.000E0
 1 3
32 GO:0005589 collagen type VI trimer 7.960E-3 4.331E-2
2.512E-1
1.000E0
 1 3
33 GO:0098647 collagen beaded filament 7.960E-3 4.331E-2
2.512E-1
1.000E0
 1 3
34 GO:0097487 multivesicular body, internal vesicle 7.960E-3 4.331E-2
2.512E-1
1.000E0
 1 3
35 GO:0005875 microtubule associated complex 8.271E-3 4.372E-2
2.536E-1
1.000E0
 3 156
36 GO:0031093 platelet alpha granule lumen 9.416E-3 4.708E-2
2.731E-1
1.000E0
 2 55
37 GO:0005871 kinesin complex 9.416E-3 4.708E-2
2.731E-1
1.000E0
 2 55
38 GO:0005862 muscle thin filament tropomyosin 1.060E-2 4.984E-2
2.891E-1
1.000E0
 1 4
39 GO:0070022 transforming growth factor beta receptor complex 1.060E-2 4.984E-2
2.891E-1
1.000E0
 1 4
40 GO:0014704 intercalated disc 1.078E-2 4.984E-2
2.891E-1
1.000E0
 2 59
Show 35 more annotations

4: Human Phenotype [Display Chart] 234 annotations before applied cutoff / 4410 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 1701 annotations before applied cutoff / 9299 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0005620 abnormal muscle contractility 7.924E-6 1.348E-2
1.081E-1
 1.348E-2 10 398
2 MP:0002626 increased heart rate 3.490E-5 2.071E-2
1.660E-1
5.936E-2
 5 84
3 MP:0000260 abnormal angiogenesis 3.652E-5 2.071E-2
1.660E-1
6.212E-2
 9 377
4 MP:0002191 abnormal artery morphology 5.156E-5 2.192E-2
1.758E-1
8.770E-2
 10 494

6: Domain [Display Chart] 484 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PF00008 EGF Pfam 3.817E-4 1.882E-2
1.272E-1
1.847E-1
 4 126
2 IPR017441 Protein kinase ATP BS InterPro 5.502E-4 1.882E-2
1.272E-1
2.663E-1
 6 379
3 PS50963 LINK 2 PROSITE 5.559E-4 1.882E-2
1.272E-1
2.691E-1
 2 13
4 PS01241 LINK 1 PROSITE 5.559E-4 1.882E-2
1.272E-1
2.691E-1
 2 13
5 IPR000538 Link dom InterPro 5.559E-4 1.882E-2
1.272E-1
2.691E-1
 2 13
6 PF00193 Xlink Pfam 5.559E-4 1.882E-2
1.272E-1
2.691E-1
 2 13
7 SM00445 LINK SMART 5.559E-4 1.882E-2
1.272E-1
2.691E-1
 2 13
8 SM00033 CH SMART 7.370E-4 1.882E-2
1.272E-1
3.567E-1
 3 65
9 PF00307 CH Pfam 9.148E-4 1.882E-2
1.272E-1
4.428E-1
 3 70
10 1.10.418.10 - Gene3D 9.534E-4 1.882E-2
1.272E-1
4.614E-1
 3 71
11 IPR000716 Thyroglobulin 1 InterPro 9.626E-4 1.882E-2
1.272E-1
4.659E-1
 2 17
12 PF00086 Thyroglobulin 1 Pfam 9.626E-4 1.882E-2
1.272E-1
4.659E-1
 2 17
13 4.10.800.10 - Gene3D 9.626E-4 1.882E-2
1.272E-1
4.659E-1
 2 17
14 PS00484 THYROGLOBULIN 1 1 PROSITE 9.626E-4 1.882E-2
1.272E-1
4.659E-1
 2 17
15 PS51162 THYROGLOBULIN 1 2 PROSITE 9.626E-4 1.882E-2
1.272E-1
4.659E-1
 2 17
16 SM00211 TY SMART 9.626E-4 1.882E-2
1.272E-1
4.659E-1
 2 17
17 PS50021 CH PROSITE 1.033E-3 1.882E-2
1.272E-1
5.002E-1
 3 73
18 4.10.410.10 - Gene3D 1.081E-3 1.882E-2
1.272E-1
5.232E-1
 2 18
19 IPR020901 Prtase inh Kunz-CS InterPro 1.081E-3 1.882E-2
1.272E-1
5.232E-1
 2 18
20 SM00131 KU SMART 1.081E-3 1.882E-2
1.272E-1
5.232E-1
 2 18
21 IPR001715 CH-domain InterPro 1.118E-3 1.882E-2
1.272E-1
5.410E-1
 3 75
22 PF00014 Kunitz BPTI Pfam 1.206E-3 1.882E-2
1.272E-1
5.838E-1
 2 19
23 PS00280 BPTI KUNITZ 1 PROSITE 1.206E-3 1.882E-2
1.272E-1
5.838E-1
 2 19
24 PS50279 BPTI KUNITZ 2 PROSITE 1.206E-3 1.882E-2
1.272E-1
5.838E-1
 2 19
25 PS01286 FA58C 2 PROSITE 1.476E-3 1.882E-2
1.272E-1
7.144E-1
 2 21
26 PS50022 FA58C 3 PROSITE 1.476E-3 1.882E-2
1.272E-1
7.144E-1
 2 21
27 PS01285 FA58C 1 PROSITE 1.476E-3 1.882E-2
1.272E-1
7.144E-1
 2 21
28 SM00231 FA58C SMART 1.476E-3 1.882E-2
1.272E-1
7.144E-1
 2 21
29 PS00107 PROTEIN KINASE ATP PROSITE 1.482E-3 1.882E-2
1.272E-1
7.175E-1
 6 459
30 IPR002223 Kunitz BPTI InterPro 1.772E-3 1.882E-2
1.272E-1
8.577E-1
 2 23
31 IPR000421 FA58C InterPro 1.930E-3 1.882E-2
1.272E-1
9.340E-1
 2 24
32 PF00754 F5 F8 type C Pfam 1.930E-3 1.882E-2
1.272E-1
9.340E-1
 2 24
33 IPR000719 Prot kinase dom InterPro 2.042E-3 1.882E-2
1.272E-1
9.882E-1
 6 489
34 PS50011 PROTEIN KINASE DOM PROSITE 2.127E-3 1.882E-2
1.272E-1
1.000E0
 6 493
35 PF12662 cEGF Pfam 2.265E-3 1.882E-2
1.272E-1
1.000E0
 2 26
36 IPR026823 cEGF InterPro 2.265E-3 1.882E-2
1.272E-1
1.000E0
 2 26
37 IPR018097 EGF Ca-bd CS InterPro 2.340E-3 1.882E-2
1.272E-1
1.000E0
 3 97
38 PS01187 EGF CA PROSITE 2.480E-3 1.882E-2
1.272E-1
1.000E0
 3 99
39 PS00010 ASX HYDROXYL PROSITE 2.552E-3 1.882E-2
1.272E-1
1.000E0
 3 100
40 PF00984 UDPG MGDP dh Pfam 2.722E-3 1.882E-2
1.272E-1
1.000E0
 1 1
41 PF15467 SGIII Pfam 2.722E-3 1.882E-2
1.272E-1
1.000E0
 1 1
42 IPR014027 UDP-Glc/GDP-Man DH C InterPro 2.722E-3 1.882E-2
1.272E-1
1.000E0
 1 1
43 IPR026729 Stathmin-2 InterPro 2.722E-3 1.882E-2
1.272E-1
1.000E0
 1 1
44 IPR026197 SCG3 InterPro 2.722E-3 1.882E-2
1.272E-1
1.000E0
 1 1
45 IPR028540 AKAP12 InterPro 2.722E-3 1.882E-2
1.272E-1
1.000E0
 1 1
46 IPR013588 MAP2 projctn InterPro 2.722E-3 1.882E-2
1.272E-1
1.000E0
 1 1
47 PF03721 UDPG MGDP dh N Pfam 2.722E-3 1.882E-2
1.272E-1
1.000E0
 1 1
48 SM00984 UDPG MGDP dh C SMART 2.722E-3 1.882E-2
1.272E-1
1.000E0
 1 1
49 PF03720 UDPG MGDP dh C Pfam 2.722E-3 1.882E-2
1.272E-1
1.000E0
 1 1
50 IPR015565 Na/K ATPase sub beta chordates InterPro 2.722E-3 1.882E-2
1.272E-1
1.000E0
 1 1
Show 45 more annotations

7: Pathway [Display Chart] 626 annotations before applied cutoff / 10916 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 576262 Extracellular matrix organization BioSystems: REACTOME 1.699E-7 1.063E-4 7.463E-4 1.063E-4 9 264
2 M5884 Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans MSigDB C2 BIOCARTA (v5.1) 3.214E-5 1.006E-2
7.058E-2
 2.012E-2 7 275
3 694606 Hepatitis B BioSystems: KEGG 1.234E-4 2.362E-2
1.658E-1
7.724E-2
 5 146
4 M1909 EGF Signaling Pathway MSigDB C2 BIOCARTA (v5.1) 1.509E-4 2.362E-2
1.658E-1
9.449E-2
 3 31
5 M14899 Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling MSigDB C2 BIOCARTA (v5.1) 1.995E-4 2.418E-2
1.697E-1
1.249E-1
 3 34
6 106048 Response to elevated platelet cytosolic Ca2+ BioSystems: REACTOME 2.318E-4 2.418E-2
1.697E-1
1.451E-1
 4 90
7 645296 EGFR Transactivation by Gastrin BioSystems: REACTOME 3.965E-4 3.384E-2
2.375E-1
2.482E-1
 2 9
8 852705 MicroRNAs in cancer BioSystems: KEGG 4.324E-4 3.384E-2
2.375E-1
2.707E-1
 6 296
9 M19118 Keratinocyte Differentiation MSigDB C2 BIOCARTA (v5.1) 4.922E-4 3.424E-2
2.403E-1
3.081E-1
 3 46
10 M18837 Map Kinase Inactivation of SMRT Corepressor MSigDB C2 BIOCARTA (v5.1) 6.031E-4 3.432E-2
2.409E-1
3.776E-1
 2 11
11 106061 Dissolution of Fibrin Clot BioSystems: REACTOME 6.031E-4 3.432E-2
2.409E-1
3.776E-1
 2 11
12 M2842 Fibrinolysis Pathway MSigDB C2 BIOCARTA (v5.1) 7.222E-4 3.665E-2
2.572E-1
4.521E-1
 2 12
13 198810 TGF Beta Signaling Pathway BioSystems: WikiPathways 8.330E-4 3.665E-2
2.572E-1
5.215E-1
 3 55
14 M16973 CBL mediated ligand-induced downregulation of EGF receptors MSigDB C2 BIOCARTA (v5.1) 8.517E-4 3.665E-2
2.572E-1
5.332E-1
 2 13
15 83119 Non-small cell lung cancer BioSystems: KEGG 8.781E-4 3.665E-2
2.572E-1
5.497E-1
 3 56
16 M6487 Platelet Amyloid Precursor Protein Pathway MSigDB C2 BIOCARTA (v5.1) 9.916E-4 3.879E-2
2.722E-1
6.207E-1
 2 14
17 106028 Hemostasis BioSystems: REACTOME 1.161E-3 4.277E-2
3.001E-1
7.271E-1
 7 493
18 83110 Glioma BioSystems: KEGG 1.355E-3 4.378E-2
3.072E-1
8.483E-1
 3 65
19 83108 Pancreatic cancer BioSystems: KEGG 1.416E-3 4.378E-2
3.072E-1
8.866E-1
 3 66
20 P00050 Plasminogen activating cascade PantherDB 1.472E-3 4.378E-2
3.072E-1
9.217E-1
 2 17
21 908257 Adrenergic signaling in cardiomyocytes BioSystems: KEGG 1.551E-3 4.378E-2
3.072E-1
9.712E-1
 4 149
22 M7552 Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy MSigDB C2 BIOCARTA (v5.1) 1.653E-3 4.378E-2
3.072E-1
1.000E0
 2 18
23 M10401 Telomeres, Telomerase, Cellular Aging, and Immortality MSigDB C2 BIOCARTA (v5.1) 1.653E-3 4.378E-2
3.072E-1
1.000E0
 2 18
24 198807 Alpha6-Beta4 Integrin Signaling Pathway BioSystems: WikiPathways 1.679E-3 4.378E-2
3.072E-1
1.000E0
 3 70
25 835410 Thyroid hormone synthesis BioSystems: KEGG 1.820E-3 4.558E-2
3.199E-1
1.000E0
 3 72
Show 20 more annotations

8: Pubmed [Display Chart] 18333 annotations before applied cutoff / 51853 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 20551380 Proteomics characterization of extracellular space components in the human aorta. Pubmed 9.289E-12 1.703E-7 1.770E-6 1.703E-7 7 101
2 21078678 V3 versican isoform alters the behavior of human melanoma cells by interfering with CD44/ErbB-dependent signaling. Pubmed 8.963E-10 5.477E-6 5.693E-5 1.643E-5 3 3
3 21078678:gr V3 versican isoform alters the behavior of human melanoma cells by interfering with CD44/ErbB-dependent signaling. GeneRIF 8.963E-10 5.477E-6 5.693E-5 1.643E-5 3 3
4 19453261:gr High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. GeneRIF 3.975E-9 1.458E-5 1.515E-4 7.288E-5 8 383
5 19453261 High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Pubmed 3.975E-9 1.458E-5 1.515E-4 7.288E-5 8 383
6 20029029 Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6. Pubmed 1.939E-8 5.923E-5 6.157E-4 3.554E-4 5 82
7 21423176 Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for Ã?-Pix in negative regulation of focal adhesion maturation. Pubmed 3.906E-7 1.512E-4 1.571E-3 7.161E-3 6 286
8 23658023 Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance. Pubmed 8.590E-7 1.512E-4 1.571E-3 1.575E-2 4 73
9 22410565 Involvement of plasminogen activator inhibitor-1 in the pathogenesis of atopic cataracts. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
10 18922856:gr Unique secretory dynamics of tissue plasminogen activator and its modulation by plasminogen activator inhibitor-1 in vascular endothelial cells. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
11 12524082 Modulation of the expression of tissue plasminogen activator and its inhibitor by hypoxia in human peritoneal and adhesion fibroblasts. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
12 22213301:gr Intense CD44 expression is a negative prognostic factor in tonsillar and base of tongue cancer. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
13 18662099:gr Investigation of association between plasminogen activator inhibitor type-1 (PAI-1) gene 4G/5G polymorphism frequency and plasma PAI-1 enzyme activity in patients with acute stroke. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
14 20686427:gr Imbalance of plasminogen activator inhibitor type-1 (PAI-1) and tissue plasminogen activator (t-PA) activity in patients with Noonan syndrome. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
15 22240314:gr Association of genetic variants of fibrinolytic system with stroke and stroke subtypes. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
16 21082259 Role of tissue plasminogen activator and plasminogen activator inhibitor polymorphism in myocardial infarction. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
17 21079779:gr Versican G3 promotes mouse mammary tumor cell growth, migration, and metastasis by influencing EGF receptor signaling. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
18 2110366 Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
19 23249568:gr Chronic circadian clock disruption induces expression of the cardiovascular risk factor plasminogen activator inhibitor-1 in mice. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
20 21501649 Antithrombotic and profibrinolytic activities of phloroglucinol. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
21 18983502:gr Acute endothelial tissue plasminogen activator release in pregnancy. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
22 16648628 Versican G3 domain regulates neurite growth and synaptic transmission of hippocampal neurons by activation of epidermal growth factor receptor. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
23 21136024:gr Role of versican V0/V1 and CD44 in the regulation of human melanoma cell behavior. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
24 21501649:gr Antithrombotic and profibrinolytic activities of phloroglucinol. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
25 20500107:gr Tissue plasminogen activator and plasminogen activator inhibitor 1 in obese and lean patients with polycystic ovary syndrome. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
26 24114008 Mental disorders and thrombotic risk. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
27 19794964:gr Tumor-endothelium cross talk blocks recruitment of neutrophils to endothelial cells: a novel mechanism of endothelial cell anergy. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
28 12145287:gr Hyaluronan promotes signaling interaction between CD44 and the transforming growth factor beta receptor I in metastatic breast tumor cells. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
29 11734664 Mean transit times and the sites of synthesis and catabolism of tissue plasminogen activator and plasminogen activator inhibitor type 1 in young subjects. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
30 17257155:gr Gene polymorphisms of tissue plasminogen activator and plasminogen activator inhibitor-1 in Turkish patients with generalized aggressive periodontitis. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
31 22213301 Intense CD44 expression is a negative prognostic factor in tonsillar and base of tongue cancer. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
32 20500107 Tissue plasminogen activator and plasminogen activator inhibitor 1 in obese and lean patients with polycystic ovary syndrome. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
33 11385207 4G/5G polymorphism of the plasminogen activator inhibitor-1 gene and insertion/deletion polymorphism of the tissue-type plasminogen activator gene in atherothrombotic stroke. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
34 18983502 Acute endothelial tissue plasminogen activator release in pregnancy. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
35 17608581:gr Tissue plasminogen activator and plasminogen activator inhibitor-1 gene polymorphisms in patients with chronic periodontitis. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
36 25306554 Effect of obesity on acute hemostatic responses to live-fire training drills. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
37 17957481:gr CD44 adhesion molecule and neuro-glial proteoglycan NG2 as invasive markers of glioma. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
38 8508955 Functional display of human plasminogen-activator inhibitor 1 (PAI-1) on phages: novel perspectives for structure-function analysis by error-prone DNA synthesis. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
39 17473573:gr Glucagon as a determinant of fibrinolytic activity in men with different stages of glucose tolerance: impact of glucagon on fibrinolysis. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
40 19492158:gr Role of viral receptors TLR3, RIG-I and MDA5 in mesothelial tissue-type plasminogen activator and plasminogen activator inhibitor-1 synthesis. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
41 16037259:gr Glycation does not alter LDL-induced secretion of tissue plasminogen activator and plasminogen activator inhibitor-1 from human aortic endothelial cells. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
42 26324706 Crystal Structure of the Michaelis Complex between Tissue-type Plasminogen Activator and Plasminogen Activators Inhibitor-1. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
43 19085655:gr Genetic architecture of tissue-type plasminogen activator and plasminogen activator inhibitor-1. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
44 23265944 CD44 interacts with EGFR and promotes head and neck squamous cell carcinoma initiation and progression. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
45 17689414:gr The PAI-1 4G/5G gene polymorphism and ischemic stroke: an association study and meta-analysis. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
46 12589088 Tissue plasminogen activator and plasminogen activator inhibitor type 1 gene polymorphism in patients with gastric ulcer complicated with bleeding. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
47 19698232 [Effects of protein kinase C activity on CD44 expression and subcellular distribution in human erythrocytes]. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
48 21158116:gr [Homocysteine' s effect on tPA and PAI-1 gene expression in HUVEC]. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
49 22577291:gr Effect of plasminogen activator inhibitor-1 and tissue plasminogen activator polymorphisms on susceptibility to type 2 diabetes in Malaysian subjects. GeneRIF 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
50 19794964 Tumor-endothelium cross talk blocks recruitment of neutrophils to endothelial cells: a novel mechanism of endothelial cell anergy. Pubmed 9.484E-7 1.512E-4 1.571E-3 1.739E-2 2 2
Show 45 more annotations

9: Interaction [Display Chart] 2285 annotations before applied cutoff / 16534 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:PHRF1 PHRF1 interactions 1.226E-5 2.800E-2
2.328E-1
 2.800E-2 3 15
2 int:CD44 CD44 interactions 5.987E-5 3.359E-2
2.792E-1
1.368E-1
 4 69
3 int:CHUK CHUK interactions 7.444E-5 3.359E-2
2.792E-1
1.701E-1
 5 142
4 int:AKAP12 AKAP12 interactions 7.676E-5 3.359E-2
2.792E-1
1.754E-1
 3 27
5 int:MMP3 MMP3 interactions 7.676E-5 3.359E-2
2.792E-1
1.754E-1
 3 27
6 int:ACTN1 ACTN1 interactions 9.648E-5 3.359E-2
2.792E-1
2.205E-1
 5 150
7 int:PLAU PLAU interactions 1.169E-4 3.359E-2
2.792E-1
2.672E-1
 3 31
8 int:LRP1 LRP1 interactions 1.176E-4 3.359E-2
2.792E-1
2.687E-1
 4 82
Show 3 more annotations

10: Cytoband [Display Chart] 51 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 8p21-p12 8p21-p12 1.471E-3 3.752E-2
1.695E-1
7.504E-2
 1 1
2 17q22-q23.2 17q22-q23.2 1.471E-3 3.752E-2
1.695E-1
7.504E-2
 1 1
3 11p15.3-p15.1 11p15.3-p15.1 2.941E-3 4.978E-2
2.249E-1
1.500E-1
 1 2
4 7p12 7p12 4.408E-3 4.978E-2
2.249E-1
2.248E-1
 1 3
5 1p22-p21 1p22-p21 7.336E-3 4.978E-2
2.249E-1
3.741E-1
 1 5
6 6q24-q25 6q24-q25 7.336E-3 4.978E-2
2.249E-1
3.741E-1
 1 5
7 2q23.1 2q23.1 1.026E-2 4.978E-2
2.249E-1
5.230E-1
 1 7
8 2q34-q35 2q34-q35 1.026E-2 4.978E-2
2.249E-1
5.230E-1
 1 7
9 15q22.1 15q22.1 1.026E-2 4.978E-2
2.249E-1
5.230E-1
 1 7
10 4p15.1 4p15.1 1.026E-2 4.978E-2
2.249E-1
5.230E-1
 1 7
11 2p22-p21 2p22-p21 1.171E-2 4.978E-2
2.249E-1
5.973E-1
 1 8
12 2p24.3 2p24.3 1.171E-2 4.978E-2
2.249E-1
5.973E-1
 1 8
Show 7 more annotations

11: Transcription Factor Binding Site [Display Chart] 419 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$GATA1 03 V$GATA1 03 8.652E-5 3.625E-2
2.398E-1
 3.625E-2 6 203

12: Gene Family [Display Chart] 43 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1250 Gla domain containing genenames.org 2.929E-4 1.259E-2
5.478E-2
 1.259E-2 2 13
2 396 Zinc fingers MYND-type|A-kinase anchoring proteins genenames.org 1.599E-3 3.438E-2
1.496E-1
6.876E-2
 2 30
3 622 Kinesins|Pleckstrin homology domain containing genenames.org 3.730E-3 4.226E-2
1.838E-1
1.604E-1
 2 46
4 628 Latent transforming growth factor beta binding proteins genenames.org 7.892E-3 4.226E-2
1.838E-1
3.394E-1
 1 4
5 1096 Erb-b2 receptor tyrosine kinases genenames.org 7.892E-3 4.226E-2
1.838E-1
3.394E-1
 1 4
6 574 Hyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing genenames.org 7.892E-3 4.226E-2
1.838E-1
3.394E-1
 1 4
7 1138 Stathmins genenames.org 7.892E-3 4.226E-2
1.838E-1
3.394E-1
 1 4
8 777 Tropomyosins genenames.org 7.892E-3 4.226E-2
1.838E-1
3.394E-1
 1 4
9 1164 CDC42 effector proteins genenames.org 9.855E-3 4.226E-2
1.838E-1
4.238E-1
 1 5
10 345 Type 1 receptor serine/threonine kinases genenames.org 1.377E-2 4.226E-2
1.838E-1
5.922E-1
 1 7
11 1246 DAN family genenames.org 1.377E-2 4.226E-2
1.838E-1
5.922E-1
 1 7
12 570 Proteoglycans genenames.org 1.377E-2 4.226E-2
1.838E-1
5.922E-1
 1 7
13 1208 ATPase Na+/K+ transporting subunits genenames.org 1.377E-2 4.226E-2
1.838E-1
5.922E-1
 1 7
14 925 Granins genenames.org 1.572E-2 4.226E-2
1.838E-1
6.761E-1
 1 8
15 939 EF-hand domain containing|Plakins genenames.org 1.572E-2 4.226E-2
1.838E-1
6.761E-1
 1 8
16 1278 SPARC family genenames.org 1.572E-2 4.226E-2
1.838E-1
6.761E-1
 1 8
17 90 Zinc fingers SWIM-type genenames.org 1.767E-2 4.470E-2
1.944E-1
7.599E-1
 1 9
18 835 C2 domain containing protein kinases genenames.org 1.962E-2 4.686E-2
2.038E-1
8.435E-1
 1 10
19 769 Tetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome genenames.org 2.169E-2 4.910E-2
2.136E-1
9.328E-1
 2 115
Show 14 more annotations

13: Coexpression [Display Chart] 4010 annotations before applied cutoff / 21867 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M13867 Genes up-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.099E-16 1.644E-12 1.459E-11 1.644E-12 14 256
2 M4737 ECM related genes up-regulated early (within 30 min) in dermal fibroblasts after addition of TGFB1 [GeneID=7040]. MSigDB C2: CGP Curated Gene Sets (v5.1) 7.296E-13 1.039E-9 9.223E-9 2.926E-9 8 58
3 M5930 Genes defining epithelial-mesenchymal transition, as in wound healing, fibrosis and metastasis. MSigDB H: Hallmark Gene Sets (v5.1) 7.776E-13 1.039E-9 9.223E-9 3.118E-9 11 200
4 M15484 Genes changed in HMLE cells (mmortalized nontransformed mammary epithelium) after RNAi knockdown of both CDH1 and CTNNB1 [GeneID=999;1499], compared to the knockdown of CDH1 alone. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.438E-11 1.442E-8 1.280E-7 5.768E-8 8 83
5 M4995 Genes specifically up-regulated in Cluster IIb of urothelial cell carcinom (UCC) tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.771E-11 4.629E-8 4.107E-7 2.314E-7 12 390
6 M14557 Genes up-regulated by expression of GAB2 [GeneID=9846] in K562 cells (chronic myeloid leukemia (CML) cell line with p210 BCR-ABL [GeneID=613;25]). MSigDB C2: CGP Curated Gene Sets (v5.1) 7.385E-11 4.878E-8 4.329E-7 2.961E-7 6 31
7 M2256 Genes commonly down-regulated in UET-13 cells (mesenchymal progenitor) by expression of EWSR1 [GeneID=2130] fusions with ETS transcription factors FLI1 and ERG [GeneID=2313 ,2078]. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.516E-11 4.878E-8 4.329E-7 3.415E-7 10 227
8 M4680 Genes up-regulated in RD cells (embryonal rhabdomyosarcoma, ERMS) by expression of PAX3- or PAX7-FOXO1 [GeneID=5077;5081;2308] fusions off retroviral vectors. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.659E-10 1.333E-7 1.183E-6 1.066E-6 10 255
9 M16026 Cluster 1: ECM related genes up-regulated in dermal fibroblasts within 30 min after TGFB1 [GeneID=7040] addition, and which kept increasing with time. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.775E-10 2.573E-7 2.283E-6 2.316E-6 5 19
10 M1521 Genes up-regulated in MMEC cells (myometrial endothelium) at 6 h after VEGFA [GeneID=7422] stimulation. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.306E-9 1.727E-6 1.532E-5 1.727E-5 6 59
11 M2310 Genes down-regulated by MYC [GeneID=4609], according to the MYC Target Gene Database. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.340E-9 1.947E-6 1.727E-5 2.141E-5 9 253
12 M2863 Genes up-regulated in epithelial lung cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v5.1) 1.195E-8 3.995E-6 3.545E-5 4.794E-5 8 192
13 M14134 Genes down-regulated in ductal carcinoma vs normal ductal breast cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.520E-8 4.690E-6 4.161E-5 6.096E-5 8 198
14 M5953 Genes up-regulated by KRAS activation. MSigDB H: Hallmark Gene Sets (v5.1) 1.644E-8 4.710E-6 4.179E-5 6.594E-5 8 200
15 M9814 Genes down-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to anaplastic thyroid carcinoma (ATC). MSigDB C2: CGP Curated Gene Sets (v5.1) 2.196E-8 5.872E-6 5.210E-5 8.808E-5 6 77
16 M14507 Genes down-regulated in luminal-like breast cancer cell lines compared to the basal-like ones. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.589E-8 1.651E-5 1.465E-4 2.642E-4 10 454
17 M9192 Genes down-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones. MSigDB C2: CGP Curated Gene Sets (v5.1) 7.448E-8 1.757E-5 1.559E-4 2.987E-4 10 460
18 M1459 Genes up-regulated in BEC (blood endothelial cells) compared to LEC (lymphatic endothelial cells). MSigDB C2: CGP Curated Gene Sets (v5.1) 8.220E-8 1.831E-5 1.625E-4 3.296E-4 7 162
19 M19391 Genes down-regulated in prostate cancer samples. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.107E-7 2.336E-5 2.073E-4 4.438E-4 10 480
20 M1834 Genes up-regulated in freshly isolated CD31- [GeneID=5175] (stromal stem cells from adipose tissue) versus the CD31+ (non-stem) counterparts. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.251E-7 2.418E-5 2.146E-4 5.015E-4 8 260
21 M12300 Up-regulated genesin the left ventricle myocardium of patients with heart failure following implantation of LVAD (left ventricular assist device). MSigDB C2: CGP Curated Gene Sets (v5.1) 1.266E-7 2.418E-5 2.146E-4 5.078E-4 6 103
22 M1565 Genes up-regulated in MMEC cells (myometrial endothelium) by VEGFA [GeneID=7422] stimulation. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.680E-7 3.063E-5 2.718E-4 6.738E-4 6 108
23 GSE37605 FOXP3 FUSION GFP VS IRES GFP TREG C57BL6 UP Genes up-regulated in T reg (FOXP3+ [GeneID=50943]) cells from B6 mice: Foxp3-Fusion-GFP versus Foxp3-ires-GFP. MSigDB C7: Immunologic Signatures (v5.1) 1.820E-7 3.173E-5 2.816E-4 7.299E-4 7 182
24 M1804 Genes up-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [GeneID=6605] off a retroviral vector. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.203E-7 3.682E-5 3.267E-4 8.836E-4 8 280
25 M8510 Top down-regulated marker genes for medulloblastoma classification: desmoplastic vs classic morphology. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.322E-7 3.724E-5 3.305E-4 9.310E-4 5 59
26 M16975 Up-regulated genes in peripheral zone of human pancreatic cancer growing in the pancreas of nude mice compared to that of the tumor from the central zone. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.455E-7 3.786E-5 3.360E-4 9.844E-4 8 284
27 M2309 Genes up-regulated in RWPE-1 cells (prostate cancer) upon expression of constitutively active form of STAT3 [GeneID=6774]. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.300E-7 4.847E-5 4.301E-4 1.323E-3 6 121
28 GSE21546 UNSTIM VS ANTI CD3 STIM DP THYMOCYTES UP Genes up-regulated in double positive thymocytes: untreated versus stimulated by anti-CD3. MSigDB C7: Immunologic Signatures (v5.1) 3.451E-7 4.847E-5 4.301E-4 1.384E-3 7 200
29 M2572 Genes in the 'mesenchymal transition signature' common to all invasive cancer types. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.506E-7 4.847E-5 4.301E-4 1.406E-3 5 64
30 M2494 Genes down-regulated in primary LEC cells (lymphatic endothelum) upon overexpression of MIR31 [GeneID=407035]. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.762E-7 5.028E-5 4.462E-4 1.508E-3 9 416
31 M9197 Genes up-regulated in MCF7 cells (breast cancer) treated with hypoxia mimetic DMOG [PubChem=3080614]. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.041E-7 6.521E-5 5.787E-4 2.021E-3 6 130
32 M2293 Genes down-regulated in ES (embryonic stem cells) with defficient SUZ12 [GeneID=23512]. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.384E-7 6.747E-5 5.987E-4 2.159E-3 8 315
33 M2504 Genes whose expression changes in Calu-6 cells (lung cancer) by TNF [GeneID=7124] were not affected by p38 inhibitor LY479754. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.950E-7 1.088E-4 9.650E-4 3.589E-3 8 337
34 M4716 Genes up-regulated in SH-SY5Y cells (neuroblastoma) after treatment with epoxomicin [PubChem=3035402], a protease inhibitor causing apoptosis. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.142E-6 1.347E-4 1.196E-3 4.581E-3 7 239
35 M15193 Genes up-regulated in pancreatic ductal adenocarcinoma (PDAC) identified in a meta analysis across four independent studies. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.407E-6 1.612E-4 1.430E-3 5.642E-3 8 358
36 M12135 Genes down-regulated in apoptotic tissues (neuroepithelium) after MDM4 [GeneID=4194] knockout. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.964E-6 2.187E-4 1.941E-3 7.875E-3 6 164
37 M4065 Down-regulated at 24 h following infection of primary human foreskin fibroblasts with CMV MSigDB C2: CGP Curated Gene Sets (v5.1) 2.041E-6 2.195E-4 1.948E-3 8.186E-3 5 91
38 M11504 Genes down-regulated in prostate cancer vs benign prostate tissue, based on a meta-analysis of five gene expression profiling studies. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.080E-6 2.195E-4 1.948E-3 8.340E-3 4 40
39 M1124 Pubertal genes up-regulated by TGFB1 [GeneID=7040]. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.338E-6 2.404E-4 2.133E-3 9.374E-3 6 169
40 M7363 Genes up-regulated in MCF7 cells (breast cancer) under hypoxia conditions. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.503E-6 2.509E-4 2.226E-3 1.004E-2 6 171
41 M11891 The postradiation tumor escape signature: genes up-regulated in tumors from irradiated stroma vs those from non-irradiated stroma. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.814E-6 2.752E-4 2.442E-3 1.128E-2 8 393
42 M9639 Genes up-regulated in MDA-MB-231 cells (breast cancer) after knockdown of SATB1 [GeneID=6304] by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.921E-6 2.789E-4 2.475E-3 1.171E-2 8 395
43 M19541 Genes commonly down-regulated in human alveolar rhabdomyosarcoma (ARMS) and its mouse model overexpressing PAX3-FOXO1 [GeneID=5077;2308] fusion. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.710E-6 3.460E-4 3.070E-3 1.488E-2 8 408
44 M2001 Genes associated with migration rate of 40 human bladder cancer cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.822E-6 3.484E-4 3.091E-3 1.533E-2 6 184
45 M6189 Genes down-regulated in MCF7 cells (breast cancer) after knockdown of both HIF1A and HIF2A [GeneID=3091;2034] by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.948E-6 3.518E-4 3.122E-3 1.583E-2 5 104
46 M13256 Genes down-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.598E-6 4.008E-4 3.557E-3 1.844E-2 6 190
47 M2899 Genes up-regulated among the high recurrence rate urothelial cell carcinoma (UCC) tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.750E-6 4.052E-4 3.596E-3 1.905E-2 4 49
48 M9483 Genes up-regulated in metastatic vs non-metastatic stromal cells originated from either bone or prostate tissues. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.200E-6 4.315E-4 3.829E-3 2.085E-2 5 110
49 M1351 Genes down-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 48 h. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.273E-6 4.315E-4 3.829E-3 2.115E-2 8 428
50 GSE28737 BCL6 HET VS BCL6 KO FOLLICULAR BCELL DN Genes down-regulated in follicular B lymphocytes with BCL6 [GeneID=604] knockout: heterozygotic versus homozygotic strains. MSigDB C7: Immunologic Signatures (v5.1) 6.173E-6 4.854E-4 4.307E-3 2.475E-2 6 200
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 2351 annotations before applied cutoff / 20974 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GSM777043 500 Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3 Immgen.org, GSE15907 2.013E-16 4.733E-13 3.947E-12 4.733E-13 17 445
2 GSM777067 500 Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2 Immgen.org, GSE15907 2.455E-12 2.042E-9 1.703E-8 5.773E-9 14 453
3 GSM777055 500 Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4 Immgen.org, GSE15907 2.605E-12 2.042E-9 1.703E-8 6.125E-9 14 455
4 GSM777050 500 Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5 Immgen.org, GSE15907 3.696E-12 2.172E-9 1.811E-8 8.688E-9 14 467
5 GSM777046 500 Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4 Immgen.org, GSE15907 2.788E-11 1.311E-8 1.093E-7 6.555E-8 13 438
6 gudmap dev gonad e13.5 M InterstitTestis Sma 500 dev gonad e13.5 M InterstitTestis Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 5.053E-11 1.892E-8 1.578E-7 1.188E-7 12 362
7 gudmap dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 k4 1000 dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 5.634E-11 1.892E-8 1.578E-7 1.325E-7 11 279
8 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 500 dev lower uro neuro e15.5 PelvicGanglion Sox10 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 6.921E-11 2.034E-8 1.696E-7 1.627E-7 12 372
9 Facebase RNAseq e10.5 Olfactory Pit 1000 K2 FacebaseRNAseq e10.5 Olfactory Pit top-relative-expression-ranked 1000 k-means-cluster#2 FaceBase_RNAseq 1.167E-9 3.048E-7 2.542E-6 2.744E-6 10 279
10 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 200 dev lower uro neuro e15.5 PelvicGanglion Sox10 top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 2.503E-9 5.885E-7 4.908E-6 5.885E-6 8 148
11 gudmap dev gonad e11.5 M GonMes Sma k3 1000 dev gonad e11.5 M GonMes Sma k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 3.423E-9 6.977E-7 5.819E-6 8.048E-6 10 312
12 GSM777043 100 Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3 Immgen.org, GSE15907 3.561E-9 6.977E-7 5.819E-6 8.373E-6 7 97
13 gudmap dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 500 dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 4.550E-9 8.229E-7 6.863E-6 1.070E-5 11 423
14 gudmap dev gonad e11.5 M GonadVasMes Flk k1 1000 dev gonad e11.5 M GonadVasMes Flk k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 7.357E-9 1.235E-6 1.030E-5 1.730E-5 10 338
15 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 200 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 1.072E-8 1.680E-6 1.401E-5 2.520E-5 8 178
16 gudmap dev gonad e13.5 M InterstitFLeydig MafB 500 dev gonad e13.5 M InterstitFLeydig MafB top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.205E-8 1.771E-6 1.477E-5 2.833E-5 10 356
17 gudmap dev gonad e13.5 F VascAssocMesenchStromOvary MafB k2 1000 dev gonad e13.5 F VascAssocMesenchStromOvary MafB k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 1.417E-8 1.959E-6 1.634E-5 3.331E-5 9 266
18 Facebase RNAseq e10.5 Neural Epithelium Overlying Medial Eminence 500 FacebaseRNAseq e10.5 Neural Epithelium Overlying Medial Eminence top-relative-expression-ranked 500 FaceBase_RNAseq 1.751E-8 2.269E-6 1.892E-5 4.117E-5 11 482
19 astrocytes Top 500 Cluster 3 astrocytes Top 500 Cluster 3 Brain Map - Barres 1.833E-8 2.269E-6 1.892E-5 4.311E-5 5 34
20 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 k1 500 dev lower uro neuro e15.5 PelvicGanglion Sox10 k-means-cluster#1 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 2.100E-8 2.351E-6 1.961E-5 4.936E-5 7 125
21 Facebase RNAseq e10.5 Neural Epithelium Overlying Lateral Eminence 500 FacebaseRNAseq e10.5 Neural Epithelium Overlying Lateral Eminence top-relative-expression-ranked 500 FaceBase_RNAseq 2.253E-8 2.351E-6 1.961E-5 5.297E-5 11 494
22 OPC Top 500 All OPC Top 500 All Brain Map - Barres 2.253E-8 2.351E-6 1.961E-5 5.297E-5 11 494
23 endothelial SubClass DCN-hi Top 500 All endothelial SubClass DCN-hi Top 500 All Brain Map - Barres 2.300E-8 2.351E-6 1.961E-5 5.408E-5 11 495
24 gudmap dev lower uro neuro e14.5 PelvicGanglion Sox10 k4 1000 dev lower uro neuro e14.5 PelvicGanglion Sox10 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 2.906E-8 2.847E-6 2.374E-5 6.832E-5 7 131
25 gudmap dev gonad e11.5 M GonadVasMes Flk k4 500 dev gonad e11.5 M GonadVasMes Flk k-means-cluster#4 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 3.611E-8 3.396E-6 2.832E-5 8.490E-5 8 208
26 DevelopingLowerUrinaryTract e14.5 urethra emap-30902 500 DevelopingLowerUrinaryTract e14.5 urethra emap-30902 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 4.361E-8 3.943E-6 3.289E-5 1.025E-4 10 408
27 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k1 1000 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 5.013E-8 4.259E-6 3.552E-5 1.179E-4 8 217
28 gudmap developingKidney e14.5 whole kidney - Wnt4 KO 1000 k2 DevelopingKidney e14.5 whole kidney - Wnt4 KO emap-6674 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 5.073E-8 4.259E-6 3.552E-5 1.193E-4 7 142
29 gudmap dev gonad e11.5 M GonadVasMes Flk 500 dev gonad e11.5 M GonadVasMes Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 5.595E-8 4.517E-6 3.767E-5 1.315E-4 10 419
30 GSM777067 100 Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2 Immgen.org, GSE15907 5.764E-8 4.517E-6 3.767E-5 1.355E-4 6 85
31 GSM777050 100 Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5 Immgen.org, GSE15907 6.631E-8 4.905E-6 4.091E-5 1.559E-4 6 87
32 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 500 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 6.677E-8 4.905E-6 4.091E-5 1.570E-4 10 427
33 gudmap dev gonad e11.5 F GonMes Sma k4 1000 dev gonad e11.5 F GonMes Sma k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 8.563E-8 6.100E-6 5.088E-5 2.013E-4 9 328
34 GSM777063 500 Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 1.088E-7 7.526E-6 6.277E-5 2.559E-4 10 450
35 PCBC ratio DE blastocyst vs DE cord blood cfr-2X-p05 DE blastocyst vs DE cord blood-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 1.197E-7 8.042E-6 6.707E-5 2.815E-4 6 96
36 gudmap developingLowerUrinaryTract P1 bladder J 1000 k2 DevelopingLowerUrinaryTract P1 bladder J emap-30374 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.537E-7 1.003E-5 8.369E-5 3.612E-4 8 251
37 DevelopingLowerUrinaryTract e14.5 urethra emap-30902 200 DevelopingLowerUrinaryTract e14.5 urethra emap-30902 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 1.741E-7 1.106E-5 9.227E-5 4.093E-4 7 170
38 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 k4 200 dev lower uro neuro e15.5 PelvicGanglion Sox10 k-means-cluster#4 top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 2.009E-7 1.217E-5 1.015E-4 4.723E-4 5 54
39 gudmap dev gonad e12.5 M InterstitLeydig MafB 500 dev gonad e12.5 M InterstitLeydig MafB top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 2.070E-7 1.217E-5 1.015E-4 4.867E-4 9 364
40 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 k4 1000 dev lower uro neuro e15.5 PelvicGanglion Sox10 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 2.071E-7 1.217E-5 1.015E-4 4.869E-4 8 261
41 Facebase RNAseq e10.5 Neural Epithelium Flanking Eminence 1000 K1 FacebaseRNAseq e10.5 Neural Epithelium Flanking Eminence top-relative-expression-ranked 1000 k-means-cluster#1 FaceBase_RNAseq 2.291E-7 1.314E-5 1.096E-4 5.387E-4 7 177
42 Facebase RNAseq e8.5 Floor Plate 500 FacebaseRNAseq e8.5 Floor Plate top-relative-expression-ranked 500 FaceBase_RNAseq 2.627E-7 1.430E-5 1.193E-4 6.177E-4 10 495
43 endothelial Top 500 All endothelial Top 500 All Brain Map - Barres 2.676E-7 1.430E-5 1.193E-4 6.292E-4 10 496
44 fetal replicating Top 500 All fetal replicating Top 500 All Brain Map - Barres 2.676E-7 1.430E-5 1.193E-4 6.292E-4 10 496
45 gudmap developingKidney e15.5 Ureteral Smooth Musc 1000 k4 DevelopingKidney e15.5 Ureteral Smooth Musc emap-28812 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.416E-7 2.307E-5 1.924E-4 1.038E-3 7 195
46 Facebase RNAseq e10.5 Neural Epithelium Overlying Lateral Eminence 500 K4 FacebaseRNAseq e10.5 Neural Epithelium Overlying Lateral Eminence top-relative-expression-ranked 500 k-means-cluster#4 FaceBase_RNAseq 4.740E-7 2.423E-5 2.020E-4 1.114E-3 6 121
47 GSM854302 500 Stromal Cells, Ep.MEChi.Th, CD45-EpCAm+Ly51-MHCIIhi, Thymus, avg-1 Immgen.org, GSE15907 5.734E-7 2.868E-5 2.392E-4 1.348E-3 9 411
48 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k2 500 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 6.306E-7 3.088E-5 2.576E-4 1.482E-3 6 127
49 gudmap dev lower uro neuro e14.5 BladdPelvicGanglion Sox10 k2 1000 dev lower uro neuro e14.5 BladdPelvicGanglion Sox10 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 7.508E-7 3.603E-5 3.005E-4 1.765E-3 7 211
50 gudmap kidney adult Mesangium Meis 500 kidney adult Mesangium Meis top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 8.192E-7 3.852E-5 3.213E-4 1.926E-3 9 429
Show 45 more annotations

15: Computational [Display Chart] 202 annotations before applied cutoff / 9399 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 module 2 Genes in module 2 MSigDb: C4 - CM: Cancer Modules 7.163E-9 1.447E-6 8.519E-6 1.447E-6 13 378
2 module 1 Genes in module 1 MSigDb: C4 - CM: Cancer Modules 4.492E-8 4.537E-6 2.671E-5 9.073E-6 12 361
3 module 12 Genes in module 12 MSigDb: C4 - CM: Cancer Modules 3.312E-7 2.187E-5 1.288E-4 6.689E-5 11 351
4 module 47 Genes in module 47 MSigDb: C4 - CM: Cancer Modules 4.331E-7 2.187E-5 1.288E-4 8.748E-5 9 216
5 module 52 Genes in module 52 MSigDb: C4 - CM: Cancer Modules 1.421E-5 5.740E-4 3.380E-3 2.870E-3 10 419
6 module 122 Genes in module 122 MSigDb: C4 - CM: Cancer Modules 3.504E-5 1.180E-3 6.946E-3 7.078E-3 6 138
7 module 19 Genes in module 19 MSigDb: C4 - CM: Cancer Modules 6.324E-5 1.825E-3 1.075E-2 1.277E-2 8 307
8 module 321 Genes in module 321 MSigDb: C4 - CM: Cancer Modules 1.241E-4 3.134E-3 1.845E-2 2.507E-2 5 108
9 module 131 Genes in module 131 MSigDb: C4 - CM: Cancer Modules 4.423E-4 9.926E-3
5.845E-2
8.934E-2
 3 33
10 module 5 Genes in module 5 MSigDb: C4 - CM: Cancer Modules 5.696E-4 1.151E-2
6.774E-2
1.151E-1
 8 423
11 module 3 Genes in module 3 MSigDb: C4 - CM: Cancer Modules 1.415E-3 2.599E-2
1.530E-1
2.859E-1
 7 375
12 module 118 Genes in module 118 MSigDb: C4 - CM: Cancer Modules 1.908E-3 3.212E-2
1.891E-1
3.854E-1
 7 395
13 module 6 Genes in module 6 MSigDb: C4 - CM: Cancer Modules 2.262E-3 3.515E-2
2.070E-1
4.569E-1
 7 407
14 module 164 Genes in module 164 MSigDb: C4 - CM: Cancer Modules 2.669E-3 3.851E-2
2.267E-1
5.391E-1
 3 61
15 module 493 Genes in module 493 MSigDb: C4 - CM: Cancer Modules 2.926E-3 3.941E-2
2.320E-1
5.911E-1
 3 63
16 module 438 Genes in module 438 MSigDb: C4 - CM: Cancer Modules 3.485E-3 4.320E-2
2.543E-1
7.041E-1
 3 67
17 GNF2 AF1Q Neighborhood of AF1Q MSigDb: C4 - CGN: Cancer Gene Neighborhood 3.687E-3 4.320E-2
2.543E-1
7.447E-1
 2 20
18 GNF2 DNM1 Neighborhood of DNM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood 3.945E-3 4.320E-2
2.543E-1
7.969E-1
 3 70
19 module 253 Genes in module 253 MSigDb: C4 - CM: Cancer Modules 4.063E-3 4.320E-2
2.543E-1
8.207E-1
 2 21
20 module 154 Genes in module 154 MSigDb: C4 - CM: Cancer Modules 4.613E-3 4.659E-2
2.743E-1
9.318E-1
 3 74
21 module 196 Genes in module 196 MSigDb: C4 - CM: Cancer Modules 4.867E-3 4.681E-2
2.756E-1
9.831E-1
 2 23
22 module 297 Genes in module 297 MSigDb: C4 - CM: Cancer Modules 5.539E-3 4.865E-2
2.864E-1
1.000E0
 3 79
23 module 357 Genes in module 357 MSigDb: C4 - CM: Cancer Modules 5.539E-3 4.865E-2
2.864E-1
1.000E0
 3 79
Show 18 more annotations

16: MicroRNA [Display Chart] 1037 annotations before applied cutoff / 19844 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-924:PITA hsa-miR-924:PITA TOP PITA 7.743E-8 8.029E-5 6.039E-4 8.029E-5 7 146
2 miR-101:PicTar miR-101:PicTar PicTar 1.105E-6 2.983E-4 2.244E-3 1.146E-3 9 430
3 ACTGTGA,MIR-27B:MSigDB ACTGTGA,MIR-27B:MSigDB MSigDB 1.522E-6 2.983E-4 2.244E-3 1.578E-3 9 447
4 ACTGTGA,MIR-27A:MSigDB ACTGTGA,MIR-27A:MSigDB MSigDB 1.522E-6 2.983E-4 2.244E-3 1.578E-3 9 447
5 hsa-miR-33a:PITA hsa-miR-33a:PITA TOP PITA 1.677E-6 2.983E-4 2.244E-3 1.739E-3 7 230
6 hsa-miR-33b:PITA hsa-miR-33b:PITA TOP PITA 1.726E-6 2.983E-4 2.244E-3 1.790E-3 7 231
7 TGGTGCT,MIR-29A:MSigDB TGGTGCT,MIR-29A:MSigDB MSigDB 2.730E-6 3.146E-4 2.366E-3 2.831E-3 9 480
8 TGGTGCT,MIR-29C:MSigDB TGGTGCT,MIR-29C:MSigDB MSigDB 2.730E-6 3.146E-4 2.366E-3 2.831E-3 9 480
9 TGGTGCT,MIR-29B:MSigDB TGGTGCT,MIR-29B:MSigDB MSigDB 2.730E-6 3.146E-4 2.366E-3 2.831E-3 9 480
10 hsa-miR-26a:PITA hsa-miR-26a:PITA TOP PITA 2.189E-5 1.892E-3 1.423E-2 2.270E-2 8 473
11 hsa-miR-26b:PITA hsa-miR-26b:PITA TOP PITA 2.189E-5 1.892E-3 1.423E-2 2.270E-2 8 473
12 hsa-miR-1297:PITA hsa-miR-1297:PITA TOP PITA 2.189E-5 1.892E-3 1.423E-2 2.270E-2 8 473
13 hsa-miR-1179:PITA hsa-miR-1179:PITA TOP PITA 4.021E-5 3.207E-3 2.412E-2 4.169E-2 6 253
14 CTACTGT,MIR-199A:MSigDB CTACTGT,MIR-199A:MSigDB MSigDB 6.748E-5 4.767E-3 3.585E-2
6.998E-2
 5 170
15 CAATGCA,MIR-33:MSigDB CAATGCA,MIR-33:MSigDB MSigDB 7.768E-5 4.767E-3 3.585E-2
8.055E-2
 4 90
16 miR-199a-star:PicTar miR-199a-star:PicTar PicTar 8.491E-5 4.767E-3 3.585E-2
8.805E-2
 7 422
17 hsa-miR-485-3p:PITA hsa-miR-485-3p:PITA TOP PITA 8.491E-5 4.767E-3 3.585E-2
8.805E-2
 7 422
18 hsa-miR-204:miRTarbase hsa-miR-204:miRTarbase miRTarbase 8.524E-5 4.767E-3 3.585E-2
8.840E-2
 3 34
19 miR-144:PicTar miR-144:PicTar PicTar 9.968E-5 4.767E-3 3.585E-2
1.034E-1
 7 433
20 CAGTATT,MIR-200B:MSigDB CAGTATT,MIR-200B:MSigDB MSigDB 1.011E-4 4.767E-3 3.585E-2
1.049E-1
 7 434
21 CAGTATT,MIR-200C:MSigDB CAGTATT,MIR-200C:MSigDB MSigDB 1.011E-4 4.767E-3 3.585E-2
1.049E-1
 7 434
22 CAGTATT,MIR-429:MSigDB CAGTATT,MIR-429:MSigDB MSigDB 1.011E-4 4.767E-3 3.585E-2
1.049E-1
 7 434
23 hsa-miR-548m:PITA hsa-miR-548m:PITA TOP PITA 1.393E-4 6.279E-3 4.723E-2
1.444E-1
 7 457
24 ATGCTGC,MIR-103:MSigDB ATGCTGC,MIR-103:MSigDB MSigDB 1.555E-4 6.293E-3 4.733E-2
1.612E-1
 5 203
25 ATGCTGC,MIR-107:MSigDB ATGCTGC,MIR-107:MSigDB MSigDB 1.555E-4 6.293E-3 4.733E-2
1.612E-1
 5 203
26 hsa-miR-1973:mirSVR highEffct hsa-miR-1973:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.691E-4 6.293E-3 4.733E-2
1.754E-1
 4 110
27 hsa-miR-103:TargetScan hsa-miR-103:TargetScan TargetScan 1.699E-4 6.293E-3 4.733E-2
1.762E-1
 7 472
28 hsa-miR-107:TargetScan hsa-miR-107:TargetScan TargetScan 1.699E-4 6.293E-3 4.733E-2
1.762E-1
 7 472
29 hsa-miR-29b:miRTarbase hsa-miR-29b:miRTarbase miRTarbase 1.853E-4 6.628E-3 4.985E-2
1.922E-1
 3 44
30 hsa-miR-578:PITA hsa-miR-578:PITA TOP PITA 1.943E-4 6.648E-3
5.001E-2
2.015E-1
 6 337
31 hsa-miR-1237:PITA hsa-miR-1237:PITA TOP PITA 1.987E-4 6.648E-3
5.001E-2
2.061E-1
 5 214
32 hsa-miR-574-3p:mirSVR lowEffct hsa-miR-574-3p:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 2.239E-4 7.257E-3
5.459E-2
2.322E-1
 6 346
33 hsa-miR-1200:PITA hsa-miR-1200:PITA TOP PITA 2.382E-4 7.486E-3
5.631E-2
2.470E-1
 6 350
34 hsa-miR-34a:miRecords TarBase hsa-miR-34a:miRecords TarBase miRecords_TarBase 2.764E-4 8.352E-3
6.282E-2
2.866E-1
 2 10
35 hsa-miR-1246:PITA hsa-miR-1246:PITA TOP PITA 2.945E-4 8.352E-3
6.282E-2
3.054E-1
 5 233
36 hsa-miR-451:mirSVR lowEffct hsa-miR-451:mirSVR conserved lowEffect-0.1-0.5 MicroRNA.org 3.117E-4 8.352E-3
6.282E-2
3.232E-1
 6 368
37 hsa-miR-1:PITA hsa-miR-1:PITA TOP PITA 3.255E-4 8.352E-3
6.282E-2
3.375E-1
 6 371
38 hsa-miR-1252:PITA hsa-miR-1252:PITA TOP PITA 3.255E-4 8.352E-3
6.282E-2
3.375E-1
 6 371
39 hsa-miR-206:PITA hsa-miR-206:PITA TOP PITA 3.255E-4 8.352E-3
6.282E-2
3.375E-1
 6 371
40 hsa-miR-671-5p:PITA hsa-miR-671-5p:PITA TOP PITA 3.302E-4 8.352E-3
6.282E-2
3.424E-1
 4 131
41 hsa-miR-613:PITA hsa-miR-613:PITA TOP PITA 3.302E-4 8.352E-3
6.282E-2
3.424E-1
 6 372
42 TGTATGA,MIR-485-3P:MSigDB TGTATGA,MIR-485-3P:MSigDB MSigDB 3.702E-4 9.140E-3
6.875E-2
3.839E-1
 4 135
43 hsa-miR-139-5p:TargetScan hsa-miR-139-5p:TargetScan TargetScan 3.921E-4 9.457E-3
7.113E-2
4.067E-1
 5 248
44 hsa-miR-107:PITA hsa-miR-107:PITA TOP PITA 4.541E-4 1.046E-2
7.871E-2
4.709E-1
 6 395
45 hsa-miR-103:PITA hsa-miR-103:PITA TOP PITA 4.541E-4 1.046E-2
7.871E-2
4.709E-1
 6 395
46 hsa-miR-380:PITA hsa-miR-380:PITA TOP PITA 4.726E-4 1.052E-2
7.913E-2
4.901E-1
 6 398
47 hsa-miR-128:miRTarbase hsa-miR-128:miRTarbase miRTarbase 4.768E-4 1.052E-2
7.913E-2
4.944E-1
 2 13
48 hsa-miR-34a:miRTarbase hsa-miR-34a:miRTarbase miRTarbase 5.127E-4 1.108E-2
8.331E-2
5.317E-1
 3 62
49 hsa-miR-633:PITA hsa-miR-633:PITA TOP PITA 5.396E-4 1.142E-2
8.589E-2
5.595E-1
 5 266
50 hsa-miR-891b:PITA hsa-miR-891b:PITA TOP PITA 5.582E-4 1.158E-2
8.708E-2
5.789E-1
 5 268
Show 45 more annotations

17: Drug [Display Chart] 12983 annotations before applied cutoff / 22098 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 7084 UP MS-275; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 8.915E-9 7.772E-5 7.810E-4 1.157E-4 8 183
2 4580 UP Beclomethasone dipropionate [5534-09-8]; Up 200; 7.6uM; PC3; HT HG-U133A Broad Institute CMAP 1.298E-8 7.772E-5 7.810E-4 1.685E-4 8 192
3 D015056 1-Methyl-3-isobutylxanthine CTD 1.796E-8 7.772E-5 7.810E-4 2.332E-4 10 391
4 C008493 methylselenic acid CTD 2.622E-8 8.510E-5 8.551E-4 3.404E-4 10 407
5 C035988 procymidone CTD 6.516E-8 1.692E-4 1.700E-3 8.460E-4 7 155
6 CID000030956 AC1L1KMJ Stitch 1.134E-7 2.035E-4 2.045E-3 1.472E-3 10 476
7 CID000024759 hyaluronan Stitch 1.481E-7 2.035E-4 2.045E-3 1.922E-3 8 263
8 6886 UP trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 1.554E-7 2.035E-4 2.045E-3 2.018E-3 7 176
9 CID000002299 AC1L1DD6 Stitch 1.744E-7 2.035E-4 2.045E-3 2.264E-3 7 179
10 CID000043187 IF-6 Stitch 1.785E-7 2.035E-4 2.045E-3 2.317E-3 4 22
11 CID000003961 losartan Stitch 1.840E-7 2.035E-4 2.045E-3 2.389E-3 9 378
12 5822 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 1.881E-7 2.035E-4 2.045E-3 2.442E-3 7 181
13 7074 UP MS-275; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 2.103E-7 2.101E-4 2.111E-3 2.731E-3 7 184
14 4314 UP Fluocinonide [356-12-7]; Up 200; 8uM; PC3; HT HG-U133A Broad Institute CMAP 2.615E-7 2.278E-4 2.289E-3 3.395E-3 7 190
15 3236 UP Maprotiline hydrochloride [10347-81-6]; Up 200; 12.8uM; MCF7; HT HG-U133A Broad Institute CMAP 2.808E-7 2.278E-4 2.289E-3 3.645E-3 7 192
16 3087 UP Nitrendipine [39562-70-4]; Up 200; 11uM; HL60; HT HG-U133A Broad Institute CMAP 2.808E-7 2.278E-4 2.289E-3 3.645E-3 7 192
17 5752 UP Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; PC3; HT HG-U133A Broad Institute CMAP 3.012E-7 2.300E-4 2.311E-3 3.910E-3 7 194
18 4524 UP (S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT HG-U133A Broad Institute CMAP 3.228E-7 2.328E-4 2.340E-3 4.191E-3 7 196
19 3764 DN Ethoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT HG-U133A Broad Institute CMAP 3.458E-7 2.363E-4 2.374E-3 4.489E-3 7 198
20 CID000024766 chondroitin sulfate Stitch 3.875E-7 2.490E-4 2.502E-3 5.031E-3 9 413
21 CID000444053 AC1L9FMG Stitch 4.027E-7 2.490E-4 2.502E-3 5.228E-3 3 7
22 C113580 U 0126 CTD 4.641E-7 2.739E-4 2.752E-3 6.025E-3 9 422
23 CID000005711 Y-27632 Stitch 7.222E-7 4.077E-4 4.097E-3 9.377E-3 9 445
24 D016559 Tacrolimus CTD 9.687E-7 5.240E-4 5.266E-3 1.258E-2 8 337
25 CID000104802 Rgd Peptide Stitch 1.224E-6 6.357E-4 6.388E-3 1.589E-2 7 239
26 DB00013 Urokinase Drug Bank 1.374E-6 6.861E-4 6.894E-3 1.784E-2 3 10
27 D002713 Chlorine CTD 1.688E-6 8.117E-4 8.156E-3 2.192E-2 8 363
28 CID000023968 argon Stitch 1.815E-6 8.417E-4 8.458E-3 2.357E-2 5 88
29 CID000004865 C22H22O8 Stitch 2.083E-6 9.324E-4 9.370E-3 2.704E-2 6 164
30 3979 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT HG-U133A Broad Institute CMAP 2.745E-6 1.163E-3 1.169E-2 3.564E-2 6 172
31 4112 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT HG-U133A Broad Institute CMAP 2.839E-6 1.163E-3 1.169E-2 3.686E-2 6 173
32 7073 UP trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 3.034E-6 1.163E-3 1.169E-2 3.939E-2 6 175
33 D014520 Urethane CTD 3.034E-6 1.163E-3 1.169E-2 3.939E-2 6 175
34 7047 UP trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 3.136E-6 1.163E-3 1.169E-2 4.071E-2 6 176
35 6546 UP trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 3.136E-6 1.163E-3 1.169E-2 4.071E-2 6 176
36 5065 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 3.347E-6 1.207E-3 1.213E-2 4.345E-2 6 178
37 5802 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 3.686E-6 1.272E-3 1.279E-2 4.785E-2 6 181
38 3075 UP Cantharidin [56-25-7]; Up 200; 20.4uM; HL60; HT HG-U133A Broad Institute CMAP 3.805E-6 1.272E-3 1.279E-2 4.940E-2 6 182
39 C568713 GSK1210151A CTD 3.822E-6 1.272E-3 1.279E-2 4.962E-2 4 46
40 6874 UP trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 3.927E-6 1.275E-3 1.281E-2
5.099E-2
 6 183
41 C581572 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea CTD 4.542E-6 1.360E-3 1.366E-2
5.897E-2
 4 48
42 4581 UP Dicyclomine hydrochloride [67-92-5]; Up 200; 11.6uM; PC3; HT HG-U133A Broad Institute CMAP 4.586E-6 1.360E-3 1.366E-2
5.955E-2
 6 188
43 3046 UP (+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Up 200; 11uM; HL60; HT HG-U133A Broad Institute CMAP 4.586E-6 1.360E-3 1.366E-2
5.955E-2
 6 188
44 C103303 alitretinoin CTD 4.608E-6 1.360E-3 1.366E-2
5.983E-2
 7 292
45 CID000040821 fendosal Stitch 5.222E-6 1.448E-3 1.455E-2
6.780E-2
 2 2
46 C095105 bexarotene CTD 5.410E-6 1.448E-3 1.455E-2
7.024E-2
 8 425
47 6762 DN Cefotiam hydrochloride; Down 200; 7.2uM; PC3; HT HG-U133A Broad Institute CMAP 5.658E-6 1.448E-3 1.455E-2
7.346E-2
 6 195
48 CID000025476 Hypertensin II Stitch 5.795E-6 1.448E-3 1.455E-2
7.523E-2
 8 429
49 4551 UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; PC3; HT HG-U133A Broad Institute CMAP 5.827E-6 1.448E-3 1.455E-2
7.565E-2
 6 196
50 5666 UP Naringin hydrate [11032-30-7]; Up 200; 6.6uM; MCF7; HT HG-U133A Broad Institute CMAP 5.827E-6 1.448E-3 1.455E-2
7.565E-2
 6 196
Show 45 more annotations

18: Disease [Display Chart] 1505 annotations before applied cutoff / 16150 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 umls:C0010072 Coronary Thrombosis DisGeNET Curated 1.934E-6 2.910E-3 2.297E-2 2.910E-3 4 30
2 umls:C0278883 Metastatic melanoma DisGeNET BeFree 6.485E-6 4.880E-3 3.852E-2 9.760E-3 8 333
3 umls:C0940937 precancerous lesions DisGeNET BeFree 1.679E-5 6.599E-3
5.210E-2
 2.527E-2 5 106
4 umls:C1519346 Skin Carcinogenesis DisGeNET BeFree 2.009E-5 6.599E-3
5.210E-2
 3.024E-2 5 110
5 umls:C0024232 Lymphatic Metastasis DisGeNET Curated 2.192E-5 6.599E-3
5.210E-2
 3.300E-2 5 112
6 umls:C0281361 Adenocarcinoma of pancreas DisGeNET BeFree 3.781E-5 8.559E-3
6.757E-2
5.691E-2
 7 309
7 umls:C0037286 Skin Neoplasms DisGeNET Curated 4.621E-5 8.559E-3
6.757E-2
6.955E-2
 6 216
8 umls:C1519670 Tumor Angiogenesis DisGeNET BeFree 5.056E-5 8.559E-3
6.757E-2
7.609E-2
 8 443
9 umls:C0007114 Malignant neoplasm of skin DisGeNET BeFree 5.119E-5 8.559E-3
6.757E-2
7.703E-2
 6 220
10 umls:C0027962 Melanocytic nevus DisGeNET Curated 5.972E-5 8.987E-3
7.095E-2
8.987E-2
 5 138
11 umls:C1511789 Desmoplastic DisGeNET BeFree 7.758E-5 1.015E-2
8.013E-2
1.168E-1
 4 75
12 umls:C0016057 Fibrosarcoma DisGeNET Curated 8.481E-5 1.015E-2
8.013E-2
1.276E-1
 6 241
13 umls:C0001510 Postoperative adhesion DisGeNET BeFree 8.966E-5 1.015E-2
8.013E-2
1.349E-1
 2 5
14 umls:C0024668 Mammary Neoplasms, Experimental DisGeNET Curated 9.442E-5 1.015E-2
8.013E-2
1.421E-1
 5 152
15 umls:C0853879 Invasive breast carcinoma DisGeNET BeFree 1.154E-4 1.158E-2
9.142E-2
1.737E-1
 7 369
16 umls:C0861727 Pancreatic adenocarcinoma metastatic DisGeNET BeFree 1.342E-4 1.263E-2
9.967E-2
2.020E-1
 2 6
17 umls:C0206681 Adenocarcinoma, Clear Cell DisGeNET Curated 1.511E-4 1.337E-2
1.056E-1
2.274E-1
 4 89
18 umls:C0729233 Dissecting aneurysm of the thoracic aorta DisGeNET BeFree 1.781E-4 1.486E-2
1.173E-1
2.680E-1
 5 174
19 umls:C0519030 Pneumonia due to Klebsiella pneumoniae DisGeNET BeFree 1.876E-4 1.486E-2
1.173E-1
2.823E-1
 2 7
20 umls:C1561643 Chronic Kidney Diseases DisGeNET Curated 2.078E-4 1.564E-2
1.235E-1
3.128E-1
 6 284
21 umls:C0039103 Synovitis DisGeNET Curated 2.278E-4 1.620E-2
1.279E-1
3.428E-1
 4 99
22 umls:C0877373 Advanced cancer DisGeNET BeFree 2.368E-4 1.620E-2
1.279E-1
3.563E-1
 4 100
23 umls:C0006287 Bronchopulmonary Dysplasia DisGeNET Curated 2.745E-4 1.796E-2
1.418E-1
4.131E-1
 5 191
24 umls:C0206718 Ganglioneuroblastoma DisGeNET BeFree 2.974E-4 1.865E-2
1.472E-1
4.476E-1
 3 43
25 umls:C0000786 Spontaneous abortion DisGeNET Curated 3.179E-4 1.914E-2
1.511E-1
4.784E-1
 4 108
26 umls:C0747845 early pregnancy DisGeNET BeFree 3.906E-4 2.146E-2
1.694E-1
5.878E-1
 4 114
27 umls:C0036631 Seminoma DisGeNET Curated 3.975E-4 2.146E-2
1.694E-1
5.982E-1
 5 207
28 umls:C0041948 Uremia DisGeNET Curated 4.124E-4 2.146E-2
1.694E-1
6.207E-1
 3 48
29 umls:C3539878 Triple Negative Breast Neoplasms DisGeNET BeFree 4.207E-4 2.146E-2
1.694E-1
6.332E-1
 7 456
30 umls:C0238394 Female Pseudohermaphroditism DisGeNET BeFree 4.384E-4 2.146E-2
1.694E-1
6.598E-1
 3 49
31 umls:C0239946 Fibrosis, Liver DisGeNET BeFree 4.420E-4 2.146E-2
1.694E-1
6.652E-1
 6 327
32 umls:C2931189 Neural crest tumor DisGeNET Curated 4.874E-4 2.182E-2
1.723E-1
7.336E-1
 2 11
33 umls:C1336538 Supratentorial Primitive Neuroectodermal Tumor DisGeNET BeFree 4.874E-4 2.182E-2
1.723E-1
7.336E-1
 2 11
34 umls:C0031099 Periodontitis DisGeNET Curated 4.930E-4 2.182E-2
1.723E-1
7.420E-1
 5 217
35 umls:C0034065 Pulmonary Embolism DisGeNET Curated 5.225E-4 2.247E-2
1.774E-1
7.863E-1
 3 52
36 umls:C1321546 Anaplastic large B-cell lymphoma DisGeNET BeFree 5.838E-4 2.374E-2
1.874E-1
8.786E-1
 2 12
37 cv:C0085580 Essential hypertension Clinical Variations 5.838E-4 2.374E-2
1.874E-1
8.786E-1
 2 12
38 umls:C0013364 Dysautonomia, Familial DisGeNET Curated 6.886E-4 2.655E-2
2.096E-1
1.000E0
 2 13
39 umls:C0206754 Neuroendocrine Tumors DisGeNET Curated 7.075E-4 2.655E-2
2.096E-1
1.000E0
 5 235
40 umls:C0153594 Malignant neoplasm of testis DisGeNET Curated 7.779E-4 2.655E-2
2.096E-1
1.000E0
 5 240
41 umls:C2697932 Loeys-Dietz Syndrome DisGeNET Curated 8.018E-4 2.655E-2
2.096E-1
1.000E0
 2 14
42 umls:C1096458 Vascular occlusion DisGeNET BeFree 8.018E-4 2.655E-2
2.096E-1
1.000E0
 2 14
43 umls:C0279702 Conventional (Clear Cell) Renal Cell Carcinoma DisGeNET Curated 8.103E-4 2.655E-2
2.096E-1
1.000E0
 6 367
44 umls:C1334177 Infiltrating Cervical Carcinoma DisGeNET BeFree 8.347E-4 2.655E-2
2.096E-1
1.000E0
 3 61
45 umls:C0038443 Stress, Psychological DisGeNET BeFree 9.171E-4 2.655E-2
2.096E-1
1.000E0
 3 63
46 umls:C0008625 Chromosome Aberrations DisGeNET Curated 9.233E-4 2.655E-2
2.096E-1
1.000E0
 2 15
47 umls:C0334287 Fibrolamellar hepatocellular carcinoma DisGeNET BeFree 9.233E-4 2.655E-2
2.096E-1
1.000E0
 2 15
48 umls:C0205748 Dysplastic Nevus DisGeNET BeFree 9.602E-4 2.655E-2
2.096E-1
1.000E0
 3 64
49 umls:C0025286 Meningioma DisGeNET Curated 1.011E-3 2.655E-2
2.096E-1
1.000E0
 6 383
50 umls:C0156181 Peritoneal adhesion DisGeNET BeFree 1.053E-3 2.655E-2
2.096E-1
1.000E0
 2 16
Show 45 more annotations