Toppgene analysis for aggregated_1964_log, IC24, negative side

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1: GO: Molecular Function [Display Chart] 269 annotations before applied cutoff / 18819 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0004859 phospholipase inhibitor activity 9.513E-6 2.559E-3 1.580E-2 2.559E-3 3 13
2 GO:0055102 lipase inhibitor activity 2.682E-5 3.608E-3 2.227E-2 7.216E-3 3 18
3 GO:0004857 enzyme inhibitor activity 4.252E-5 3.813E-3 2.354E-2 1.144E-2 8 393
4 GO:0019834 phospholipase A2 inhibitor activity 6.380E-5 4.291E-3 2.649E-2 1.716E-2 2 4
5 GO:0061134 peptidase regulator activity 9.148E-5 4.922E-3 3.038E-2 2.461E-2 6 223
6 GO:0005253 anion channel activity 2.504E-4 1.123E-2
6.931E-2
6.736E-2
 4 93
7 GO:0003729 mRNA binding 3.152E-4 1.211E-2
7.479E-2
8.480E-2
 5 180
8 GO:0008199 ferric iron binding 4.725E-4 1.589E-2
9.808E-2
1.271E-1
 2 10
9 GO:0044548 S100 protein binding 8.138E-4 2.242E-2
1.384E-1
2.189E-1
 2 13
10 GO:0005544 calcium-dependent phospholipid binding 8.335E-4 2.242E-2
1.384E-1
2.242E-1
 3 56
11 GO:0032036 myosin heavy chain binding 9.474E-4 2.317E-2
1.430E-1
2.548E-1
 2 14
12 GO:0048306 calcium-dependent protein binding 1.593E-3 3.571E-2
2.205E-1
4.285E-1
 3 70
13 GO:0005254 chloride channel activity 2.420E-3 4.220E-2
2.605E-1
6.510E-1
 3 81
14 GO:0004866 endopeptidase inhibitor activity 2.436E-3 4.220E-2
2.605E-1
6.554E-1
 4 171
15 GO:0061135 endopeptidase regulator activity 2.760E-3 4.220E-2
2.605E-1
7.423E-1
 4 177
16 GO:0030414 peptidase inhibitor activity 2.932E-3 4.220E-2
2.605E-1
7.886E-1
 4 180
17 GO:0008509 anion transmembrane transporter activity 2.939E-3 4.220E-2
2.605E-1
7.906E-1
 5 297
18 GO:0048270 methionine adenosyltransferase regulator activity 3.295E-3 4.220E-2
2.605E-1
8.862E-1
 1 1
19 GO:0033676 double-stranded DNA-dependent ATPase activity 3.295E-3 4.220E-2
2.605E-1
8.862E-1
 1 1
20 GO:0070320 inward rectifier potassium channel inhibitor activity 3.295E-3 4.220E-2
2.605E-1
8.862E-1
 1 1
21 GO:0032896 palmitoyl-CoA 9-desaturase activity 3.295E-3 4.220E-2
2.605E-1
8.862E-1
 1 1
22 GO:0015108 chloride transmembrane transporter activity 3.472E-3 4.245E-2
2.621E-1
9.339E-1
 3 92
23 GO:0004867 serine-type endopeptidase inhibitor activity 3.913E-3 4.577E-2
2.826E-1
1.000E0
 3 96
Show 18 more annotations

2: GO: Biological Process [Display Chart] 2323 annotations before applied cutoff / 18785 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0001525 angiogenesis 3.095E-7 4.876E-4 4.061E-3 7.189E-4 11 465
2 GO:0002902 regulation of B cell apoptotic process 7.525E-7 4.876E-4 4.061E-3 1.748E-3 4 22
3 GO:2001233 regulation of apoptotic signaling pathway 8.781E-7 4.876E-4 4.061E-3 2.040E-3 10 411
4 GO:2000106 regulation of leukocyte apoptotic process 1.002E-6 4.876E-4 4.061E-3 2.328E-3 6 101
5 GO:0048145 regulation of fibroblast proliferation 1.062E-6 4.876E-4 4.061E-3 2.467E-3 6 102
6 GO:0048144 fibroblast proliferation 1.259E-6 4.876E-4 4.061E-3 2.926E-3 6 105
7 GO:0071709 membrane assembly 1.523E-6 5.053E-4 4.209E-3 3.537E-3 4 26
8 GO:0001783 B cell apoptotic process 2.075E-6 6.026E-4 5.019E-3 4.821E-3 4 28
9 GO:0061515 myeloid cell development 2.742E-6 6.539E-4 5.446E-3 6.370E-3 5 67
10 GO:0071887 leukocyte apoptotic process 2.887E-6 6.539E-4 5.446E-3 6.707E-3 6 121
11 GO:1903034 regulation of response to wounding 3.280E-6 6.539E-4 5.446E-3 7.618E-3 10 476
12 GO:0044091 membrane biogenesis 3.609E-6 6.539E-4 5.446E-3 8.384E-3 4 32
13 GO:0070228 regulation of lymphocyte apoptotic process 3.659E-6 6.539E-4 5.446E-3 8.501E-3 5 71
14 GO:0001765 membrane raft assembly 4.041E-6 6.706E-4 5.585E-3 9.388E-3 3 10
15 GO:0007160 cell-matrix adhesion 5.082E-6 7.573E-4 6.307E-3 1.181E-2 7 206
16 GO:0098751 bone cell development 5.216E-6 7.573E-4 6.307E-3 1.212E-2 4 35
17 GO:0030100 regulation of endocytosis 9.320E-6 1.195E-3 9.956E-3 2.165E-2 7 226
18 GO:0070227 lymphocyte apoptotic process 9.974E-6 1.195E-3 9.956E-3 2.317E-2 5 87
19 GO:0042254 ribosome biogenesis 1.033E-5 1.195E-3 9.956E-3 2.400E-2 8 322
20 GO:2001234 negative regulation of apoptotic signaling pathway 1.045E-5 1.195E-3 9.956E-3 2.427E-2 7 230
21 GO:0031589 cell-substrate adhesion 1.081E-5 1.195E-3 9.956E-3 2.510E-2 8 324
22 GO:0002903 negative regulation of B cell apoptotic process 1.214E-5 1.282E-3 1.068E-2 2.821E-2 3 14
23 GO:0007569 cell aging 1.613E-5 1.629E-3 1.357E-2 3.747E-2 5 96
24 GO:0045806 negative regulation of endocytosis 1.725E-5 1.670E-3 1.391E-2 4.007E-2 4 47
25 GO:0022613 ribonucleoprotein complex biogenesis 2.152E-5 1.984E-3 1.653E-2 4.999E-2 9 468
26 GO:2001236 regulation of extrinsic apoptotic signaling pathway 2.243E-5 1.984E-3 1.653E-2
5.211E-2
 6 173
27 GO:0006364 rRNA processing 2.306E-5 1.984E-3 1.653E-2
5.358E-2
 7 260
28 GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 2.697E-5 2.117E-3 1.763E-2
6.265E-2
 3 18
29 GO:0031579 membrane raft organization 2.697E-5 2.117E-3 1.763E-2
6.265E-2
 3 18
30 GO:0016072 rRNA metabolic process 2.734E-5 2.117E-3 1.763E-2
6.351E-2
 7 267
31 GO:0033031 positive regulation of neutrophil apoptotic process 3.209E-5 2.373E-3 1.976E-2
7.454E-2
 2 3
32 GO:0090150 establishment of protein localization to membrane 3.269E-5 2.373E-3 1.976E-2
7.594E-2
 8 378
33 GO:0010810 regulation of cell-substrate adhesion 3.373E-5 2.374E-3 1.977E-2
7.835E-2
 6 186
34 GO:1903035 negative regulation of response to wounding 3.581E-5 2.447E-3 2.038E-2
8.319E-2
 6 188
35 GO:0050900 leukocyte migration 3.863E-5 2.564E-3 2.135E-2
8.973E-2
 8 387
36 GO:0030850 prostate gland development 3.993E-5 2.577E-3 2.146E-2
9.277E-2
 4 58
37 GO:0070371 ERK1 and ERK2 cascade 4.142E-5 2.601E-3 2.166E-2
9.623E-2
 7 285
38 GO:0006612 protein targeting to membrane 4.520E-5 2.763E-3 2.301E-2
1.050E-1
 6 196
39 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 4.924E-5 2.933E-3 2.443E-2
1.144E-1
 5 121
40 GO:0034329 cell junction assembly 5.059E-5 2.938E-3 2.447E-2
1.175E-1
 6 200
41 GO:0034109 homotypic cell-cell adhesion 5.323E-5 3.016E-3 2.512E-2
1.237E-1
 8 405
42 GO:0007568 aging 7.041E-5 3.894E-3 3.243E-2
1.636E-1
 7 310
43 GO:0048146 positive regulation of fibroblast proliferation 7.479E-5 4.040E-3 3.365E-2
1.737E-1
 4 68
44 GO:0006402 mRNA catabolic process 8.154E-5 4.305E-3 3.585E-2
1.894E-1
 6 218
45 GO:0045629 negative regulation of T-helper 2 cell differentiation 1.065E-4 5.498E-3 4.579E-2
2.474E-1
 2 5
46 GO:0035710 CD4-positive, alpha-beta T cell activation 1.155E-4 5.816E-3 4.844E-2
2.684E-1
 4 76
47 GO:0046636 negative regulation of alpha-beta T cell activation 1.177E-4 5.816E-3 4.844E-2
2.734E-1
 3 29
48 GO:0008360 regulation of cell shape 1.279E-4 6.184E-3
5.150E-2
2.971E-1
 5 148
49 GO:0033032 regulation of myeloid cell apoptotic process 1.304E-4 6.184E-3
5.150E-2
3.030E-1
 3 30
50 GO:0001953 negative regulation of cell-matrix adhesion 1.586E-4 7.030E-3
5.854E-2
3.685E-1
 3 32
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 239 annotations before applied cutoff / 19172 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0005925 focal adhesion 3.994E-9 4.216E-7 2.553E-6 9.546E-7 12 393
2 GO:0005924 cell-substrate adherens junction 4.602E-9 4.216E-7 2.553E-6 1.100E-6 12 398
3 GO:0030055 cell-substrate junction 5.292E-9 4.216E-7 2.553E-6 1.265E-6 12 403
4 GO:0045177 apical part of cell 1.062E-8 6.347E-7 3.843E-6 2.539E-6 12 429
5 GO:0005912 adherens junction 4.019E-8 1.921E-6 1.163E-5 9.606E-6 12 484
6 GO:0044420 extracellular matrix component 6.757E-6 2.692E-4 1.630E-3 1.615E-3 6 143
7 GO:0031012 extracellular matrix 1.208E-5 3.709E-4 2.246E-3 2.887E-3 9 444
8 GO:0016324 apical plasma membrane 1.241E-5 3.709E-4 2.246E-3 2.967E-3 8 337
9 GO:0005578 proteinaceous extracellular matrix 2.885E-5 7.066E-4 4.279E-3 6.894E-3 8 379
10 GO:0005604 basement membrane 2.956E-5 7.066E-4 4.279E-3 7.066E-3 5 111
11 GO:0030016 myofibril 7.866E-5 1.709E-3 1.035E-2 1.880E-2 6 221
12 GO:0043292 contractile fiber 1.102E-4 2.196E-3 1.330E-2 2.635E-2 6 235
13 GO:0042383 sarcolemma 1.360E-4 2.286E-3 1.385E-2 3.250E-2 5 153
14 GO:0016323 basolateral plasma membrane 1.384E-4 2.286E-3 1.385E-2 3.309E-2 6 245
15 GO:0015629 actin cytoskeleton 1.461E-4 2.286E-3 1.385E-2 3.493E-2 8 478
16 GO:0035749 myelin sheath adaxonal region 1.531E-4 2.286E-3 1.385E-2 3.658E-2 2 6
17 GO:0031232 extrinsic component of external side of plasma membrane 3.651E-4 5.132E-3 3.108E-2
8.725E-2
 2 9
18 GO:0043209 myelin sheath 5.137E-4 6.821E-3 4.131E-2
1.228E-1
 5 204
19 GO:0022626 cytosolic ribosome 5.962E-4 7.500E-3 4.542E-2
1.425E-1
 4 119
20 GO:0044449 contractile fiber part 6.656E-4 7.954E-3 4.817E-2
1.591E-1
 5 216
21 GO:0005903 brush border 9.044E-4 1.029E-2
6.233E-2
2.162E-1
 4 133
22 GO:0043220 Schmidt-Lanterman incisure 1.052E-3 1.142E-2
6.918E-2
2.513E-1
 2 15
23 GO:0072562 blood microparticle 1.184E-3 1.230E-2
7.449E-2
2.829E-1
 4 143
24 GO:0097517 contractile actin filament bundle 1.390E-3 1.329E-2
8.045E-2
3.321E-1
 3 68
25 GO:0001725 stress fiber 1.390E-3 1.329E-2
8.045E-2
3.321E-1
 3 68
26 GO:0019897 extrinsic component of plasma membrane 1.483E-3 1.363E-2
8.253E-2
3.543E-1
 4 152
27 GO:0043218 compact myelin 1.698E-3 1.503E-2
9.104E-2
4.059E-1
 2 19
28 GO:0032432 actin filament bundle 1.773E-3 1.513E-2
9.164E-2
4.237E-1
 3 74
29 GO:0030141 secretory granule 1.847E-3 1.522E-2
9.216E-2
4.413E-1
 6 401
30 GO:0042641 actomyosin 2.062E-3 1.597E-2
9.670E-2
4.928E-1
 3 78
31 GO:0019898 extrinsic component of membrane 2.071E-3 1.597E-2
9.670E-2
4.950E-1
 5 279
32 GO:0001726 ruffle 2.184E-3 1.631E-2
9.877E-2
5.219E-1
 4 169
33 GO:0044391 ribosomal subunit 2.478E-3 1.795E-2
1.087E-1
5.922E-1
 4 175
34 GO:0034774 secretory granule lumen 2.634E-3 1.836E-2
1.112E-1
6.296E-1
 3 85
35 GO:0098862 cluster of actin-based cell projections 2.689E-3 1.836E-2
1.112E-1
6.426E-1
 4 179
36 GO:0030667 secretory granule membrane 3.001E-3 1.992E-2
1.207E-1
7.173E-1
 3 89
37 GO:0002102 podosome 3.181E-3 2.010E-2
1.217E-1
7.603E-1
 2 26
38 GO:0005902 microvillus 3.196E-3 2.010E-2
1.217E-1
7.638E-1
 3 91
39 GO:0016460 myosin II complex 3.428E-3 2.059E-2
1.247E-1
8.194E-1
 2 27
40 GO:0005769 early endosome 3.445E-3 2.059E-2
1.247E-1
8.235E-1
 5 314
41 GO:0030017 sarcomere 3.928E-3 2.290E-2
1.387E-1
9.389E-1
 4 199
42 GO:0060205 cytoplasmic vesicle lumen 4.650E-3 2.594E-2
1.571E-1
1.000E0
 3 104
43 GO:0048770 pigment granule 4.776E-3 2.594E-2
1.571E-1
1.000E0
 3 105
44 GO:0042470 melanosome 4.776E-3 2.594E-2
1.571E-1
1.000E0
 3 105
45 GO:0031983 vesicle lumen 5.166E-3 2.744E-2
1.662E-1
1.000E0
 3 108
46 GO:1990667 PCSK9-AnxA2 complex 6.457E-3 3.026E-2
1.833E-1
1.000E0
 1 2
47 GO:0008043 intracellular ferritin complex 6.457E-3 3.026E-2
1.833E-1
1.000E0
 1 2
48 GO:0032311 angiogenin-PRI complex 6.457E-3 3.026E-2
1.833E-1
1.000E0
 1 2
49 GO:0035692 macrophage migration inhibitory factor receptor complex 6.457E-3 3.026E-2
1.833E-1
1.000E0
 1 2
50 GO:0048269 methionine adenosyltransferase complex 6.457E-3 3.026E-2
1.833E-1
1.000E0
 1 2
Show 45 more annotations

4: Human Phenotype [Display Chart] 479 annotations before applied cutoff / 4410 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0000956 Acanthosis nigricans 3.748E-5 1.334E-2
9.005E-2
 1.795E-2 3 18
2 HP:0003306 Spinal rigidity 6.065E-5 1.334E-2
9.005E-2
 2.905E-2 3 21
3 HP:0007485 Absence of subcutaneous fat 8.355E-5 1.334E-2
9.005E-2
 4.002E-2 2 4
4 HP:0008180 Mildly elevated creatine phosphokinase 1.172E-4 1.403E-2
9.470E-2
5.612E-2
 3 26
5 HP:0000160 Narrow mouth {has synonym type="layperson"} 2.304E-4 2.207E-2
1.490E-1
1.104E-1
 4 83
6 HP:0002987 Elbow flexion contracture 5.717E-4 4.012E-2
2.708E-1
2.738E-1
 3 44
7 HP:0000411 Protruding ear 7.395E-4 4.012E-2
2.708E-1
3.542E-1
 3 48
8 HP:0003803 Type 1 muscle fiber predominance 7.538E-4 4.012E-2
2.708E-1
3.611E-1
 2 11
9 HP:0001533 Slender build {has synonym type="layperson"} 7.538E-4 4.012E-2
2.708E-1
3.611E-1
 2 11
Show 4 more annotations

5: Mouse Phenotype [Display Chart] 2226 annotations before applied cutoff / 9299 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0005341 decreased susceptibility to atherosclerosis 1.423E-7 3.167E-4 2.624E-3 3.167E-4 6 47
2 MP:0000260 abnormal angiogenesis 3.925E-7 4.369E-4 3.620E-3 8.738E-4 12 377
3 MP:0005338 atherosclerotic lesions 1.043E-6 7.741E-4 6.414E-3 2.322E-3 7 104
4 MP:0003991 arteriosclerosis 1.435E-6 7.983E-4 6.614E-3 3.193E-3 7 109
5 MP:0005340 altered susceptibility to atherosclerosis 2.205E-6 9.817E-4 8.133E-3 4.908E-3 6 74
6 MP:0000609 abnormal liver physiology 5.279E-6 1.959E-3 1.623E-2 1.175E-2 11 399
7 MP:0005023 abnormal wound healing 8.738E-6 2.779E-3 2.302E-2 1.945E-2 8 201
8 MP:0002139 abnormal hepatobiliary system physiology 1.176E-5 3.272E-3 2.711E-2 2.618E-2 11 434
9 MP:0008719 impaired neutrophil recruitment 1.448E-5 3.581E-3 2.967E-2 3.223E-2 5 60
10 MP:0005265 abnormal blood urea nitrogen level 2.120E-5 4.720E-3 3.910E-2 4.720E-2 8 227
11 MP:0009644 uremia 2.405E-5 4.867E-3 4.032E-2
5.354E-2
 8 231
12 MP:0002908 delayed wound healing 2.678E-5 4.967E-3 4.115E-2
5.960E-2
 5 68
13 MP:0011131 abnormal lung endothelial cell physiology 2.926E-5 5.010E-3 4.151E-2
6.513E-2
 3 12
14 MP:0008721 abnormal chemokine level 3.538E-5 5.610E-3 4.648E-2
7.875E-2
 5 72
15 MP:0005565 increased blood urea nitrogen level 3.781E-5 5.610E-3 4.648E-2
8.416E-2
 7 179
16 MP:0001209 spontaneous skin ulceration 4.887E-5 6.799E-3
5.633E-2
1.088E-1
 4 39
17 MP:0002412 increased susceptibility to bacterial infection 5.300E-5 6.940E-3
5.750E-2
1.180E-1
 8 258
18 MP:0002981 increased liver weight 6.454E-5 7.982E-3
6.613E-2
1.437E-1
 6 133
19 MP:0009738 enlarged prostate gland anterior lobe 8.133E-5 9.052E-3
7.500E-2
1.810E-1
 2 3
20 MP:0014045 Mallory bodies 8.133E-5 9.052E-3
7.500E-2
1.810E-1
 2 3
21 MP:0004847 abnormal liver weight 1.205E-4 1.271E-2
1.053E-1
2.683E-1
 7 215
22 MP:0003303 peritoneal inflammation 1.256E-4 1.271E-2
1.053E-1
2.795E-1
 3 19
23 MP:0013193 sebaceous gland hypoplasia 1.621E-4 1.504E-2
1.246E-1
3.609E-1
 2 4
24 MP:0005284 increased saturated fatty acid level 1.621E-4 1.504E-2
1.246E-1
3.609E-1
 2 4
25 MP:0001163 abnormal prostate gland anterior lobe morphology 1.711E-4 1.523E-2
1.262E-1
3.808E-1
 3 21
26 MP:0001860 liver inflammation 1.854E-4 1.587E-2
1.315E-1
4.127E-1
 6 161
27 MP:0012778 abnormal liver triglyceride level 2.050E-4 1.690E-2
1.400E-1
4.563E-1
 6 164
28 MP:0001798 impaired macrophage phagocytosis 2.189E-4 1.740E-2
1.442E-1
4.873E-1
 4 57
29 MP:0004003 abnormal vascular endothelial cell physiology 2.342E-4 1.791E-2
1.484E-1
5.214E-1
 4 58
30 MP:0003156 abnormal leukocyte migration 2.413E-4 1.791E-2
1.484E-1
5.372E-1
 6 169
31 MP:0011139 increased lung endothelial cell proliferation 2.693E-4 1.908E-2
1.581E-1
5.994E-1
 2 5
32 MP:0020186 altered susceptibility to bacterial infection 2.746E-4 1.908E-2
1.581E-1
6.112E-1
 8 327
33 MP:0008713 abnormal cytokine level 2.845E-4 1.908E-2
1.581E-1
6.332E-1
 9 418
34 MP:0001195 flaky skin 2.915E-4 1.908E-2
1.581E-1
6.489E-1
 3 25
35 MP:0002463 abnormal neutrophil physiology 3.098E-4 1.970E-2
1.632E-1
6.896E-1
 6 177
36 MP:0001219 thick epidermis 3.275E-4 2.020E-2
1.674E-1
7.291E-1
 5 115
37 MP:0000599 enlarged liver 3.446E-4 2.020E-2
1.674E-1
7.672E-1
 7 255
38 MP:0008835 abnormal intercellular signaling peptide or protein level 3.448E-4 2.020E-2
1.674E-1
7.675E-1
 9 429
39 MP:0003710 abnormal physiological neovascularization 3.680E-4 2.048E-2
1.697E-1
8.191E-1
 3 27
40 MP:0000836 abnormal substantia nigra morphology 3.680E-4 2.048E-2
1.697E-1
8.191E-1
 3 27
41 MP:0009763 increased sensitivity to induced morbidity/mortality 3.791E-4 2.058E-2
1.705E-1
8.438E-1
 8 343
42 MP:0002406 increased susceptibility to infection 4.018E-4 2.129E-2
1.764E-1
8.943E-1
 9 438
43 MP:0004848 abnormal liver size 4.513E-4 2.336E-2
1.936E-1
1.000E0
 9 445
44 MP:0002874 decreased hemoglobin content 4.787E-4 2.422E-2
2.007E-1
1.000E0
 6 192
45 MP:0000811 hippocampal neuron degeneration 5.051E-4 2.422E-2
2.007E-1
1.000E0
 3 30
46 MP:0005329 abnormal myocardium layer morphology 5.058E-4 2.422E-2
2.007E-1
1.000E0
 9 452
47 MP:0000208 decreased hematocrit 5.198E-4 2.422E-2
2.007E-1
1.000E0
 6 195
48 MP:0020148 abnormal sensitivity to induced morbidity/mortality 5.223E-4 2.422E-2
2.007E-1
1.000E0
 9 454
49 MP:0005601 increased angiogenesis 5.572E-4 2.459E-2
2.038E-1
1.000E0
 3 31
50 MP:0011138 abnormal lung endothelial cell proliferation 5.617E-4 2.459E-2
2.038E-1
1.000E0
 2 7
Show 45 more annotations

6: Domain [Display Chart] 423 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PF08976 EF-hand 11 Pfam 3.122E-5 6.603E-3 4.375E-2 1.321E-2 2 3
2 IPR015070 EF hand DJBP InterPro 3.122E-5 6.603E-3 4.375E-2 1.321E-2 2 3
3 IPR002946 CLIC InterPro 1.551E-4 2.187E-2
1.449E-1
6.561E-2
 2 6
4 PF00822 PMP22 Claudin Pfam 2.978E-4 2.221E-2
1.472E-1
1.260E-1
 3 40
5 PS01221 PMP22 1 PROSITE 3.699E-4 2.221E-2
1.472E-1
1.565E-1
 2 9
6 PS01222 PMP22 2 PROSITE 3.699E-4 2.221E-2
1.472E-1
1.565E-1
 2 9
7 IPR004032 PMP22 EMP MP20 InterPro 3.699E-4 2.221E-2
1.472E-1
1.565E-1
 2 9
8 IPR004031 PMP22/EMP/MP20/Claudin InterPro 4.228E-4 2.221E-2
1.472E-1
1.788E-1
 3 45
9 1.10.220.10 - Gene3D 7.948E-4 2.221E-2
1.472E-1
3.362E-1
 2 13
10 IPR018502 Annexin repeat InterPro 9.253E-4 2.221E-2
1.472E-1
3.914E-1
 2 14
11 SM00335 ANX SMART 9.253E-4 2.221E-2
1.472E-1
3.914E-1
 2 14
12 PS00223 ANNEXIN PROSITE 9.253E-4 2.221E-2
1.472E-1
3.914E-1
 2 14
13 PF00191 Annexin Pfam 9.253E-4 2.221E-2
1.472E-1
3.914E-1
 2 14
14 IPR018252 Annexin repeat CS InterPro 9.253E-4 2.221E-2
1.472E-1
3.914E-1
 2 14
15 IPR001464 Annexin InterPro 1.065E-3 2.221E-2
1.472E-1
4.507E-1
 2 15
16 PF01015 Ribosomal S3Ae Pfam 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
17 IPR005913 dTDP dehydrorham reduct InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
18 IPR002388 AnnexinI InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
19 IPR003932 EMP 1 InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
20 IPR003934 EMP 3 InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
21 IPR001380 Ribosomal L13e InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
22 PS00884 OSTEOPONTIN PROSITE 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
23 PF01294 Ribosomal L13e Pfam 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
24 PS00088 SOD MN PROSITE 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
25 IPR002389 AnnexinII InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
26 PF02777 Sod Fe C Pfam 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
27 IPR033832 PEDF InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
28 IPR018281 Ribosomal S3Ae CS InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
29 IPR018256 Ribosomal L13e CS InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
30 SM00017 OSTEO SMART 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
31 IPR019832 Mn/Fe SOD C InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
32 SM01397 Ribosomal S3Ae SMART 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
33 PF05022 SRP40 C Pfam 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
34 IPR030277 VDAC2 InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
35 IPR030259 CLIC-1 InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
36 IPR029903 RmlD-like-bd InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
37 IPR015503 Cortactin InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
38 IPR019841 Osteopontin CS InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
39 IPR028476 S100-A10 InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
40 PS01104 RIBOSOMAL L13E PROSITE 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
41 IPR030257 CLIC-4 InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
42 PS01191 RIBOSOMAL S3AE PROSITE 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
43 IPR005711 Ribosomal S5 euk/arc InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
44 IPR008122 TF AP2 beta InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
45 IPR030685 Serotransferrin mammal InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
46 IPR027500 Ribosomal S1/3 euk InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
47 PF00865 Osteopontin Pfam 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
48 IPR015628 SV/p205 InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
49 IPR028482 S100A11 InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
50 IPR028538 CHI3L1 InterPro 3.256E-3 2.221E-2
1.472E-1
1.000E0
 1 1
Show 45 more annotations

7: Pathway [Display Chart] 477 annotations before applied cutoff / 10916 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 83067 Focal adhesion BioSystems: KEGG 2.940E-5 1.402E-2
9.460E-2
 1.402E-2 7 206
2 83071 Tight junction BioSystems: KEGG 2.900E-4 2.663E-2
1.796E-1
1.383E-1
 5 134
3 137939 Direct p53 effectors BioSystems: Pathway Interaction Database 2.900E-4 2.663E-2
1.796E-1
1.383E-1
 5 134
4 198912 Prostaglandin Synthesis and Regulation BioSystems: WikiPathways 3.290E-4 2.663E-2
1.796E-1
1.569E-1
 3 31
5 149807 Bacterial invasion of epithelial cells BioSystems: KEGG 3.347E-4 2.663E-2
1.796E-1
1.597E-1
 4 76
6 83089 Regulation of actin cytoskeleton BioSystems: KEGG 3.349E-4 2.663E-2
1.796E-1
1.598E-1
 6 215
7 105968 Formation of a pool of free 40S subunits BioSystems: REACTOME 5.026E-4 2.829E-2
1.909E-1
2.397E-1
 5 151
8 83068 ECM-receptor interaction BioSystems: KEGG 5.365E-4 2.829E-2
1.909E-1
2.559E-1
 4 86
9 160955 L13a-mediated translational silencing of Ceruloplasmin expression BioSystems: REACTOME 6.730E-4 2.829E-2
1.909E-1
3.210E-1
 5 161
10 105973 GTP hydrolysis and joining of the 60S ribosomal subunit BioSystems: REACTOME 6.922E-4 2.829E-2
1.909E-1
3.302E-1
 5 162
11 366241 Nonsense Mediated Decay Enhanced by the Exon Junction Complex BioSystems: REACTOME 7.118E-4 2.829E-2
1.909E-1
3.395E-1
 5 163
12 366240 Nonsense-Mediated Decay BioSystems: REACTOME 7.118E-4 2.829E-2
1.909E-1
3.395E-1
 5 163
13 105966 Eukaryotic Translation Initiation BioSystems: REACTOME 8.380E-4 2.855E-2
1.926E-1
3.997E-1
 5 169
14 105967 Cap-dependent Translation Initiation BioSystems: REACTOME 8.380E-4 2.855E-2
1.926E-1
3.997E-1
 5 169
15 138036 FoxO family signaling BioSystems: Pathway Interaction Database 1.130E-3 3.420E-2
2.307E-1
5.388E-1
 3 47
16 672461 Iron metabolism in placenta BioSystems: WikiPathways 1.215E-3 3.420E-2
2.307E-1
5.796E-1
 2 12
17 198780 Senescence and Autophagy BioSystems: WikiPathways 1.219E-3 3.420E-2
2.307E-1
5.814E-1
 4 107
18 106261 Muscle contraction BioSystems: REACTOME 1.433E-3 3.797E-2
2.562E-1
6.835E-1
 3 51
19 83083 Leukocyte transendothelial migration BioSystems: KEGG 1.750E-3 4.159E-2
2.806E-1
8.345E-1
 4 118
20 83103 Pathogenic Escherichia coli infection BioSystems: KEGG 1.783E-3 4.159E-2
2.806E-1
8.506E-1
 3 55
21 672459 Pathogenic Escherichia coli infection BioSystems: WikiPathways 1.878E-3 4.159E-2
2.806E-1
8.960E-1
 3 56
22 198853 Cytoplasmic Ribosomal Proteins BioSystems: WikiPathways 1.918E-3 4.159E-2
2.806E-1
9.150E-1
 4 121
23 105965 Translation BioSystems: REACTOME 2.063E-3 4.278E-2
2.886E-1
9.839E-1
 5 207
24 83104 Shigellosis BioSystems: KEGG 2.402E-3 4.773E-2
3.220E-1
1.000E0
 3 61
25 198832 Adipogenesis BioSystems: WikiPathways 2.707E-3 4.855E-2
3.275E-1
1.000E0
 4 133
26 83036 Ribosome BioSystems: KEGG 2.857E-3 4.855E-2
3.275E-1
1.000E0
 4 135
27 782000 Proteoglycans in cancer BioSystems: KEGG 2.962E-3 4.855E-2
3.275E-1
1.000E0
 5 225
28 106110 Integrin cell surface interactions BioSystems: REACTOME 3.007E-3 4.855E-2
3.275E-1
1.000E0
 3 66
29 M295 Genes related to PIP3 signaling in cardiac myocytes MSigDB C2 BIOCARTA (v5.1) 3.138E-3 4.855E-2
3.275E-1
1.000E0
 3 67
30 105978 Eukaryotic Translation Termination BioSystems: REACTOME 3.257E-3 4.855E-2
3.275E-1
1.000E0
 4 140
31 106077 Viral mRNA Translation BioSystems: REACTOME 3.257E-3 4.855E-2
3.275E-1
1.000E0
 4 140
32 105977 Peptide chain elongation BioSystems: REACTOME 3.257E-3 4.855E-2
3.275E-1
1.000E0
 4 140
Show 27 more annotations

8: Pubmed [Display Chart] 21329 annotations before applied cutoff / 51853 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 21319273 An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells. Pubmed 5.564E-22 1.187E-17 1.251E-16 1.187E-17 17 397
2 22623428 Proteomic analysis of ¿4�1 integrin adhesion complexes reveals ¿-subunit-dependent protein recruitment. Pubmed 2.037E-20 2.173E-16 2.291E-15 4.345E-16 17 491
3 21423176 Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for Ã?-Pix in negative regulation of focal adhesion maturation. Pubmed 1.306E-15 9.287E-12 9.793E-11 2.786E-11 12 286
4 23874603 HIV-1 Vpr modulates macrophage metabolic pathways: a SILAC-based quantitative analysis. Pubmed 8.807E-14 4.019E-10 4.238E-9 1.878E-9 9 135
5 22304920 PKC¿ promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria. Pubmed 9.422E-14 4.019E-10 4.238E-9 2.010E-9 9 136
6 17620599 Functional specialization of beta-arrestin interactions revealed by proteomic analysis. Pubmed 1.739E-13 6.183E-10 6.520E-9 3.710E-9 11 317
7 15047060 Analysis of proteins copurifying with the CD4/lck complex using one-dimensional polyacrylamide gel electrophoresis and mass spectrometry: comparison with affinity-tag based protein detection and evaluation of different solubilization methods. Pubmed 4.085E-13 1.200E-9 1.266E-8 8.712E-9 7 53
8 25324306 hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling. Pubmed 4.502E-13 1.200E-9 1.266E-8 9.602E-9 11 346
9 23398456 The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. Pubmed 8.495E-12 2.013E-8 2.123E-7 1.812E-7 10 328
10 26641092 The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells. Pubmed 1.539E-11 3.281E-8 3.460E-7 3.281E-7 9 239
11 26561776 Reversible oxidation of phosphatase and tensin homolog (PTEN) alters its interactions with signaling and regulatory proteins. Pubmed 3.513E-11 6.812E-8 7.184E-7 7.494E-7 7 98
12 7821789 Construction of a human full-length cDNA bank. Pubmed 7.014E-11 1.247E-7 1.315E-6 1.496E-6 7 108
13 16385451 A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Pubmed 8.885E-11 1.385E-7 1.461E-6 1.895E-6 10 417
14 16385451:gr A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. GeneRIF 9.094E-11 1.385E-7 1.461E-6 1.940E-6 10 418
15 21150319 Proteomic profiling of Myc-associated proteins. Pubmed 1.029E-10 1.464E-7 1.543E-6 2.195E-6 7 114
16 19805454 Quantitative nanoproteomics for protein complexes (QNanoPX) related to estrogen transcriptional action. Pubmed 1.787E-10 2.382E-7 2.512E-6 3.812E-6 6 64
17 16130169 Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis. Pubmed 4.750E-10 5.960E-7 6.284E-6 1.013E-5 6 75
18 23125841 Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1. Pubmed 6.021E-10 7.135E-7 7.524E-6 1.284E-5 8 241
19 24189400 Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms. Pubmed 9.691E-10 1.088E-6 1.147E-5 2.067E-5 8 256
20 19190083 Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. Pubmed 1.255E-9 1.339E-6 1.412E-5 2.677E-5 5 39
21 15161933 Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins. Pubmed 1.505E-9 1.529E-6 1.612E-5 3.211E-5 7 167
22 25337248 Prognostic and predictive values of SPP1, PAI and caveolin-1 in patients with oral squamous cell carcinoma. Pubmed 1.709E-9 1.657E-6 1.747E-5 3.645E-5 3 3
23 16289162 The identification of myocilin-associated proteins in the human trabecular meshwork. Pubmed 1.850E-9 1.715E-6 1.809E-5 3.945E-5 5 42
24 16791210 Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins. Pubmed 2.969E-9 2.639E-6 2.783E-5 6.333E-5 5 46
25 21630459 Proteomic characterization of the human sperm nucleus. Pubmed 3.127E-9 2.668E-6 2.814E-5 6.671E-5 9 437
26 25468996 E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Pubmed 4.024E-9 3.301E-6 3.481E-5 8.583E-5 8 307
27 24244333 Profiling of Parkin-binding partners using tandem affinity purification. Pubmed 5.838E-9 4.601E-6 4.851E-5 1.245E-4 7 203
28 25659154 ABCE1 is a highly conserved RNA silencing suppressor. Pubmed 6.040E-9 4.601E-6 4.851E-5 1.288E-4 7 204
29 2969496 Chromosomal localization of the human genes for lipocortin I and lipocortin II. Pubmed 6.830E-9 5.024E-6 5.297E-5 1.457E-4 3 4
30 23463506 The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. Pubmed 7.877E-9 5.590E-6 5.895E-5 1.680E-4 7 212
31 15592455 Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. Pubmed 8.125E-9 5.590E-6 5.895E-5 1.733E-4 8 336
32 24332808 PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry. Pubmed 8.907E-9 5.937E-6 6.260E-5 1.900E-4 8 340
33 25277244 The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets. Pubmed 1.187E-8 7.673E-6 8.091E-5 2.532E-4 7 225
34 21182205 Identification of proteins associated with ligand-activated estrogen receptor ¿ in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS. Pubmed 2.131E-8 1.337E-5 1.410E-4 4.545E-4 7 245
35 23792823 Protein isoform-specific validation defines multiple chloride intracellular channel and tropomyosin isoforms as serological biomarkers of ovarian cancer. Pubmed 3.409E-8 2.078E-5 2.191E-4 7.272E-4 3 6
36 22952844 Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex. Pubmed 3.969E-8 2.348E-5 2.476E-4 8.466E-4 6 156
37 19199708 Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Pubmed 4.074E-8 2.348E-5 2.476E-4 8.689E-4 8 414
38 24965446 Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex. Pubmed 5.045E-8 2.832E-5 2.986E-4 1.076E-3 5 80
39 18289715:gr Direct effects of alcohol on hepatic fibrinolytic balance: implications for alcoholic liver disease. GeneRIF 5.961E-8 3.260E-5 3.438E-4 1.271E-3 3 7
40 23084401 The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus. Pubmed 6.387E-8 3.405E-5 3.591E-4 1.362E-3 6 169
41 16159877 Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin. Pubmed 6.614E-8 3.441E-5 3.628E-4 1.411E-3 6 170
42 23455922 Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. Pubmed 7.330E-8 3.722E-5 3.925E-4 1.563E-3 8 447
43 17361185 14-3-3sigma controls mitotic translation to facilitate cytokinesis. Pubmed 7.704E-8 3.821E-5 4.029E-4 1.643E-3 5 87
44 25144556 Autophagic degradation of the inhibitory p53 isoform ¿133p53¿ as a regulatory mechanism for p53-mediated senescence. Pubmed 8.160E-8 3.956E-5 4.171E-4 1.740E-3 5 88
45 23402259 Quantitative study of the interactome of PKC¿ involved in the EGF-induced tumor cell chemotaxis. Pubmed 1.057E-7 5.008E-5 5.281E-4 2.254E-3 6 184
46 26460568 Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy. Pubmed 1.163E-7 5.391E-5 5.684E-4 2.480E-3 6 187
47 26693507 The dynamic interactome of human Aha1 upon Y223 phosphorylation. Pubmed 1.264E-7 5.735E-5 6.047E-4 2.695E-3 5 96
48 20000738 Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma. Pubmed 1.712E-7 7.609E-5 8.024E-4 3.652E-3 5 102
49 22145905 A cohesin-RAD21 interactome. Pubmed 2.176E-7 9.474E-5 9.990E-4 4.642E-3 6 208
50 21362503 Protein profile of exosomes from trabecular meshwork cells. Pubmed 4.022E-7 1.675E-4 1.766E-3 8.579E-3 4 49
Show 45 more annotations

9: Interaction [Display Chart] 3334 annotations before applied cutoff / 16534 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:VCAM1 VCAM1 interactions 8.093E-10 1.928E-6 1.676E-5 2.698E-6 14 447
2 int:SLC25A5 SLC25A5 interactions 1.157E-9 1.928E-6 1.676E-5 3.857E-6 9 129
3 int:MYH9 MYH9 interactions 1.973E-9 1.934E-6 1.681E-5 6.576E-6 12 319
4 int:RPL12 RPL12 interactions 2.889E-9 1.934E-6 1.681E-5 9.631E-6 9 143
5 int:INVS INVS interactions 2.961E-9 1.934E-6 1.681E-5 9.872E-6 8 98
6 int:CD4 CD4 interactions 3.481E-9 1.934E-6 1.681E-5 1.161E-5 8 100
7 int:RPL10A RPL10A interactions 6.581E-9 2.900E-6 2.520E-5 2.194E-5 9 157
8 int:RPL15 RPL15 interactions 6.958E-9 2.900E-6 2.520E-5 2.320E-5 9 158
9 int:RPL28 RPL28 interactions 1.441E-8 5.336E-6 4.637E-5 4.803E-5 7 77
10 int:MYOC MYOC interactions 1.808E-8 6.028E-6 5.238E-5 6.028E-5 6 46
11 int:RPL13 RPL13 interactions 5.636E-8 1.708E-5 1.484E-4 1.879E-4 9 201
12 int:FLOT1 FLOT1 interactions 7.795E-8 2.090E-5 1.816E-4 2.599E-4 7 98
13 int:YWHAQ YWHAQ interactions 8.150E-8 2.090E-5 1.816E-4 2.717E-4 12 446
14 int:ATF2 ATF2 interactions 1.045E-7 2.488E-5 2.162E-4 3.483E-4 9 216
15 int:RPS20 RPS20 interactions 1.152E-7 2.560E-5 2.224E-4 3.840E-4 8 156
16 int:RPS9 RPS9 interactions 1.400E-7 2.822E-5 2.452E-4 4.669E-4 8 160
17 int:RPA1 RPA1 interactions 1.439E-7 2.822E-5 2.452E-4 4.797E-4 12 470
18 int:FLNA FLNA interactions 1.555E-7 2.881E-5 2.503E-4 5.186E-4 10 300
19 int:RPS3 RPS3 interactions 2.064E-7 3.428E-5 2.979E-4 6.883E-4 9 234
20 int:STAU1 STAU1 interactions 2.108E-7 3.428E-5 2.979E-4 7.028E-4 10 310
21 int:NCL NCL interactions 2.219E-7 3.428E-5 2.979E-4 7.398E-4 9 236
22 int:MYO19 MYO19 interactions 2.335E-7 3.428E-5 2.979E-4 7.786E-4 8 171
23 int:RPS13 RPS13 interactions 2.442E-7 3.428E-5 2.979E-4 8.142E-4 8 172
24 int:ABCE1 ABCE1 interactions 2.469E-7 3.428E-5 2.979E-4 8.233E-4 9 239
25 int:MYH10 MYH10 interactions 2.571E-7 3.428E-5 2.979E-4 8.571E-4 6 71
26 int:ACTB ACTB interactions 2.826E-7 3.624E-5 3.149E-4 9.422E-4 10 320
27 int:RPL7 RPL7 interactions 3.175E-7 3.921E-5 3.407E-4 1.059E-3 8 178
28 int:ARRB1 ARRB1 interactions 3.490E-7 4.045E-5 3.515E-4 1.164E-3 9 249
29 int:RPL13A RPL13A interactions 3.519E-7 4.045E-5 3.515E-4 1.173E-3 7 122
30 int:PAN2 PAN2 interactions 5.489E-7 6.100E-5 5.300E-4 1.830E-3 10 344
31 int:RPL27A RPL27A interactions 6.328E-7 6.624E-5 5.755E-4 2.110E-3 7 133
32 int:RPLP0 RPLP0 interactions 6.357E-7 6.624E-5 5.755E-4 2.120E-3 8 195
33 int:IGFBP5 IGFBP5 interactions 6.660E-7 6.728E-5 5.846E-4 2.220E-3 4 19
34 int:U2AF2 U2AF2 interactions 7.697E-7 7.335E-5 6.374E-4 2.566E-3 10 357
35 int:RPS6 RPS6 interactions 7.700E-7 7.335E-5 6.374E-4 2.567E-3 8 200
36 int:RPS26 RPS26 interactions 8.529E-7 7.899E-5 6.863E-4 2.844E-3 7 139
37 int:ASB16 ASB16 interactions 1.023E-6 9.060E-5 7.873E-4 3.409E-3 4 21
38 int:RPL21 RPL21 interactions 1.033E-6 9.060E-5 7.873E-4 3.443E-3 7 143
39 int:RPS23 RPS23 interactions 1.134E-6 9.693E-5 8.423E-4 3.780E-3 7 145
40 int:RPS3A RPS3A interactions 1.282E-6 1.056E-4 9.172E-4 4.274E-3 8 214
41 int:CSNK2A1 CSNK2A1 interactions 1.354E-6 1.056E-4 9.172E-4 4.515E-3 11 476
42 int:DDX3X DDX3X interactions 1.361E-6 1.056E-4 9.172E-4 4.539E-3 7 149
43 int:RPL19 RPL19 interactions 1.361E-6 1.056E-4 9.172E-4 4.539E-3 7 149
44 int:RPL31 RPL31 interactions 1.424E-6 1.079E-4 9.374E-4 4.747E-3 7 150
45 int:RPS25 RPS25 interactions 1.489E-6 1.079E-4 9.375E-4 4.963E-3 7 151
46 int:EZR EZR interactions 1.489E-6 1.079E-4 9.375E-4 4.963E-3 7 151
47 int:RPL7A RPL7A interactions 1.773E-6 1.258E-4 1.093E-3 5.913E-3 7 155
48 int:FBL FBL interactions 2.422E-6 1.682E-4 1.462E-3 8.074E-3 8 233
49 int:RPL18 RPL18 interactions 2.481E-6 1.688E-4 1.467E-3 8.272E-3 7 163
50 int:RPS28 RPS28 interactions 3.255E-6 2.170E-4 1.886E-3 1.085E-2 6 109
Show 45 more annotations

10: Cytoband [Display Chart] 57 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 9p13 9p13 7.526E-4 3.344E-2
1.548E-1
 4.290E-2 2 23
2 18p11.31 18p11.31 1.200E-3 3.344E-2
1.548E-1
6.838E-2
 2 29
3 4q31.2-q31.3 4q31.2-q31.3 1.760E-3 3.344E-2
1.548E-1
1.003E-1
 1 1
4 5q34-q35 5q34-q35 3.517E-3 4.009E-2
1.856E-1
2.005E-1
 1 2
5 1q21-q25 1q21-q25 3.517E-3 4.009E-2
1.856E-1
2.005E-1
 1 2

11: Transcription Factor Binding Site [Display Chart] 368 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 47 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 307 Chloride intracellular channels genenames.org 9.320E-5 4.381E-3 1.944E-2 4.381E-3 2 6
2 404 Annexins genenames.org 4.792E-4 8.745E-3 3.881E-2 2.252E-2 2 13
3 657 Myosin light chains|EF-hand domain containing genenames.org 5.582E-4 8.745E-3 3.881E-2 2.623E-2 2 14
4 459 S100 calcium binding proteins|EF-hand domain containing genenames.org 1.274E-3 1.497E-2
6.642E-2
5.986E-2
 2 21
5 542 Endogenous ligands genenames.org 2.983E-3 2.610E-2
1.158E-1
1.402E-1
 4 237
6 728 S ribosomal proteins genenames.org 3.332E-3 2.610E-2
1.158E-1
1.566E-1
 2 34
7 739 Serpin peptidase inhibitors genenames.org 3.937E-3 2.643E-2
1.173E-1
1.850E-1
 2 37
8 106 Y box binding proteins genenames.org 7.566E-3 3.233E-2
1.435E-1
3.556E-1
 1 3
9 612 Lamins genenames.org 7.566E-3 3.233E-2
1.435E-1
3.556E-1
 1 3
10 306 Voltage dependent anion channels genenames.org 7.566E-3 3.233E-2
1.435E-1
3.556E-1
 1 3
11 908 Transferrins genenames.org 7.566E-3 3.233E-2
1.435E-1
3.556E-1
 1 3
12 867 Chloride channel accessory genenames.org 1.008E-2 3.383E-2
1.501E-1
4.736E-1
 1 4
13 777 Tropomyosins genenames.org 1.008E-2 3.383E-2
1.501E-1
4.736E-1
 1 4
14 1238 Exon junction complex genenames.org 1.008E-2 3.383E-2
1.501E-1
4.736E-1
 1 4
15 902 C2 tensin-type domain containing|PTEN protein phosphatases|Phosphoinositide phosphatases genenames.org 1.258E-2 3.478E-2
1.543E-1
5.912E-1
 1 5
16 610 Intermediate filaments Type III genenames.org 1.258E-2 3.478E-2
1.543E-1
5.912E-1
 1 5
17 1279 Deafness associated genes|SIBLING family genenames.org 1.258E-2 3.478E-2
1.543E-1
5.912E-1
 1 5
18 570 Proteoglycans genenames.org 1.757E-2 3.927E-2
1.743E-1
8.257E-1
 1 7
19 1053 14-3-3 phospho-serine/phospho-threonine binding proteins genenames.org 1.757E-2 3.927E-2
1.743E-1
8.257E-1
 1 7
20 816 Chitinases genenames.org 1.757E-2 3.927E-2
1.743E-1
8.257E-1
 1 7
21 863 EF-hand domain containing genenames.org 1.786E-2 3.927E-2
1.743E-1
8.394E-1
 3 219
22 950 Gelsolin/villins genenames.org 2.005E-2 3.927E-2
1.743E-1
9.425E-1
 1 8
23 837 DNAJ (HSP40) heat shock proteins|C2 tensin-type domain containing genenames.org 2.005E-2 3.927E-2
1.743E-1
9.425E-1
 1 8
24 553 Fatty acid desaturases genenames.org 2.005E-2 3.927E-2
1.743E-1
9.425E-1
 1 8
Show 19 more annotations

13: Coexpression [Display Chart] 4848 annotations before applied cutoff / 21867 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M11197 Housekeeping genes identified as expressed across 19 normal tissues. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.071E-16 2.943E-12 2.667E-11 2.943E-12 17 389
2 M2293 Genes down-regulated in ES (embryonic stem cells) with defficient SUZ12 [GeneID=23512]. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.931E-12 1.195E-8 1.083E-7 2.391E-8 13 315
3 M4952 Genes down-regulated in comparison of plasmacytoid dendritic cells (DC) versus myeloid DCs. MSigDB C7: Immunologic Signatures (v5.1) 1.156E-11 1.868E-8 1.693E-7 5.604E-8 11 200
4 M19541 Genes commonly down-regulated in human alveolar rhabdomyosarcoma (ARMS) and its mouse model overexpressing PAX3-FOXO1 [GeneID=5077;2308] fusion. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.235E-10 1.497E-7 1.357E-6 5.989E-7 13 408
5 M18149 Genes up-regulated in peripheral blood monocytes by HGF [GeneID=3082]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.664E-10 1.613E-7 1.462E-6 8.067E-7 13 418
6 M11884 Genes up-regulated at the peak of an antigen response of naive CD8+ [GeneID=925;926] T-cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.636E-10 1.899E-7 1.721E-6 1.278E-6 12 346
7 M4971 Genes down-regulated in comparison of plasmacytoid dendritic cells (DC) from influenza vaccinee at day 7 post-vaccination versus myeloid DCs at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v5.1) 2.742E-10 1.899E-7 1.721E-6 1.329E-6 10 200
8 M15193 Genes up-regulated in pancreatic ductal adenocarcinoma (PDAC) identified in a meta analysis across four independent studies. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.891E-10 2.345E-7 2.125E-6 1.886E-6 12 358
9 M14507 Genes down-regulated in luminal-like breast cancer cell lines compared to the basal-like ones. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.576E-10 2.345E-7 2.125E-6 2.218E-6 13 454
10 M1484 Genes up-regulated in pancreatic cells from mice with double knockout of E2F1 [GeneID=1869] and E2F2 [GeneID=1870] compared to wild type. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.837E-10 2.345E-7 2.125E-6 2.345E-6 9 151
11 GSE26488 CTRL VS PEPTIDE INJECTION OT2 THYMOCYTE DN Genes down-regulated in double positive thymocytes from OT-2 transgenic mice: control versus injected with agonist peptide. MSigDB C7: Immunologic Signatures (v5.1) 2.293E-9 1.011E-6 9.159E-6 1.112E-5 9 180
12 M2001 Genes associated with migration rate of 40 human bladder cancer cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.782E-9 1.124E-6 1.019E-5 1.349E-5 9 184
13 M3645 Genes up-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.320E-9 1.474E-6 1.336E-5 2.094E-5 12 443
14 M1399 Retinoic acid-responsive genes up-regulated in hepatocellular carcinoma (HCC) samples of TRIM24 [GeneID=8805] knockout mice. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.387E-9 1.474E-6 1.336E-5 2.127E-5 6 47
15 M3013 Genes down-regulated in comparison of naive versus effector CD8 T cells at the peak expansion phase (day8 after LCMV-Armstrong infection). MSigDB C7: Immunologic Signatures (v5.1) 5.778E-9 1.474E-6 1.336E-5 2.801E-5 9 200
16 M4467 Genes down-regulated in comparison of neutrophils versusl monocytes. MSigDB C7: Immunologic Signatures (v5.1) 5.778E-9 1.474E-6 1.336E-5 2.801E-5 9 200
17 GSE22140 GERMFREE VS SPF MOUSE CD4 TCELL DN Genes down-regulated in healthy CD4 [GeneID=920] T cells: germ free versus specific pathogen free. MSigDB C7: Immunologic Signatures (v5.1) 5.778E-9 1.474E-6 1.336E-5 2.801E-5 9 200
18 GSE23568 CTRL TRANSDUCED VS WT CD8 TCELL UP Genes up-regulated CD8 T cells: mock transduced versus wildtype. MSigDB C7: Immunologic Signatures (v5.1) 5.778E-9 1.474E-6 1.336E-5 2.801E-5 9 200
19 M4486 Genes down-regulated in comparison of naive B cells versus day 0 monocytes. MSigDB C7: Immunologic Signatures (v5.1) 5.778E-9 1.474E-6 1.336E-5 2.801E-5 9 200
20 M9192 Genes down-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.577E-9 1.594E-6 1.445E-5 3.189E-5 12 460
21 M2086 Genes up-regulated in ITNK cells (T-lymphocyte progenitors (DN3 cells) reprogrammed to natural killer (NK) cells by ablation of BCL11B [GeneID=64919] gene), compared to the parental DN3 cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.702E-8 3.930E-6 3.562E-5 8.252E-5 10 307
22 M5902 Genes mediating programmed cell death (apoptosis) by activation of caspases. MSigDB H: Hallmark Gene Sets (v5.1) 1.992E-8 4.389E-6 3.978E-5 9.656E-5 8 161
23 M863 Myb-regulated genes in MCF7 (breast cancer) and lung epithelial cell lines overexpressing MYBL2, MYBL1 or MYB [GeneID=4605;4603;4602]. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.374E-8 5.004E-6 4.536E-5 1.151E-4 10 318
24 M14072 Genes regulated by hypoxia, based on literature searches. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.020E-8 6.100E-6 5.529E-5 1.464E-4 9 242
25 M6326 Genes up-regulated in spleen from wildtype mice: control versus LPS. MSigDB C7: Immunologic Signatures (v5.1) 3.335E-8 6.231E-6 5.647E-5 1.617E-4 8 172
26 M16586 Genes up-regulated in serrated vs conventional colorectal carcinoma (CRC) samples. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.342E-8 6.231E-6 5.647E-5 1.620E-4 7 112
27 M12636 Genes up-regulated in peripheral blood monocytes by CSF2RB (GM-CSF) and IL4 [GeneID=1437;3565]. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.215E-8 7.569E-6 6.860E-5 2.044E-4 10 338
28 M4433 Genes down-regulated in comparison of naive B cells versus memory IgG IgA B cells. MSigDB C7: Immunologic Signatures (v5.1) 9.918E-8 1.443E-5 1.308E-4 4.808E-4 8 198
29 M4942 Genes down-regulated in comparison of B cells versus plasmacytoid dendritic cells (pDC) . MSigDB C7: Immunologic Signatures (v5.1) 1.031E-7 1.443E-5 1.308E-4 4.998E-4 8 199
30 M3119 Genes down-regulated in comparison of naive T cells versus memory T cells. MSigDB C7: Immunologic Signatures (v5.1) 1.031E-7 1.443E-5 1.308E-4 4.998E-4 8 199
31 M3017 Genes down-regulated in comparison of naive versus memory CD8 T cells (day 40+ after LCMV-Armstrong infection). MSigDB C7: Immunologic Signatures (v5.1) 1.072E-7 1.443E-5 1.308E-4 5.195E-4 8 200
32 GSE19401 NAIVE VS IMMUNIZED MOUSE PLN FOLLICULAR DC UP Genes up-regulated in ex vivo follicular dendritic cells from peripheral lymph nodes: naïve versus immunized mice. MSigDB C7: Immunologic Signatures (v5.1) 1.072E-7 1.443E-5 1.308E-4 5.195E-4 8 200
33 M3636 Genes up-regulated in comparison of unstimulated CD8 T cells at 48 h versus CD8 T cells at 48 h after treatment with trichostatin A (TSA) [PubChem=5562]. MSigDB C7: Immunologic Signatures (v5.1) 1.072E-7 1.443E-5 1.308E-4 5.195E-4 8 200
34 M4945 Genes up-regulated in comparison of monocytes versus plasmacytoid dendritic cells (pDC). MSigDB C7: Immunologic Signatures (v5.1) 1.072E-7 1.443E-5 1.308E-4 5.195E-4 8 200
35 M5930 Genes defining epithelial-mesenchymal transition, as in wound healing, fibrosis and metastasis. MSigDB H: Hallmark Gene Sets (v5.1) 1.072E-7 1.443E-5 1.308E-4 5.195E-4 8 200
36 GSE18893 TCONV VS TREG 24H CULTURE UP Genes up-regulated in lymphocytes treated with medium for 24h: T conv versus T reg cells. MSigDB C7: Immunologic Signatures (v5.1) 1.072E-7 1.443E-5 1.308E-4 5.195E-4 8 200
37 M1850 Known targets of AP1 that were down-regulated by overexpression of TAM67, a dominant-negative form of JUN [GeneID=3725]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.447E-7 1.896E-5 1.719E-4 7.016E-4 4 17
38 M2122 Genes correlated with mesenchymal type of glioblastoma multiforme tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.934E-7 2.467E-5 2.236E-4 9.375E-4 8 216
39 M6921 Top 50 marker genes for glioblastoma multiforme (GBM), a class of high grade glioma. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.113E-7 2.627E-5 2.381E-4 1.024E-3 5 46
40 M14098 Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 24 h time point that were not down-regulated at the previous time point, 20 h. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.273E-7 2.755E-5 2.497E-4 1.102E-3 7 148
41 M7013 Upregulated in the vastus lateralis muscle of middle aged rhesus monkeys subjected to caloric restriction since young adulthood vs age matched controls MSigDB C2: CGP Curated Gene Sets (v5.1) 3.189E-7 3.771E-5 3.418E-4 1.546E-3 6 95
42 M2567 Genes down-regulated in T98 cells (glioma) 48 h after treatment with interferon beta. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.953E-7 4.563E-5 4.136E-4 1.917E-3 5 52
43 M2807 Genes up-regulated in astrogia cells. MSigDB C6: Oncogenic Signatures (v5.1) 4.326E-7 4.877E-5 4.420E-4 2.097E-3 6 100
44 M5644 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMC from patients with acute S. aureus infection. MSigDB C7: Immunologic Signatures (v5.1) 5.159E-7 5.684E-5 5.152E-4 2.501E-3 7 167
45 GSE13547 2H VS 12 H ANTI IGM STIM ZFX KO BCELL DN Genes down-regulated in B lymphocytes stimulated by anti-IgM: ZFX [GeneID=7543] knockout (2h) versus wildtype (12h). MSigDB C7: Immunologic Signatures (v5.1) 5.817E-7 6.267E-5 5.680E-4 2.820E-3 7 170
46 M1617 Genes down-regulated in aorta biopsies from mice treated with rosiglitazone [PubChem=77999]. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.108E-7 6.360E-5 5.765E-4 2.961E-3 6 106
47 M2769 Genes down-regulated during early stages of differentiation of embryoid bodies from V6.5 embryonic stem cells. MSigDB C6: Oncogenic Signatures (v5.1) 6.295E-7 6.360E-5 5.765E-4 3.052E-3 7 172
48 M1218 Genes up-regulated in hepatocellular carcinoma (HCC) developed by transgenic mice overexpressing a secretable form of EGF [GeneID=1950] in liver. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.299E-7 6.360E-5 5.765E-4 3.054E-3 5 57
49 M2310 Genes down-regulated by MYC [GeneID=4609], according to the MYC Target Gene Database. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.428E-7 6.360E-5 5.765E-4 3.116E-3 8 253
50 M1120 Genes up-regulated in brain tumors induced by retroviral delivery of PDGFB [GeneID=5155]. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.878E-7 6.669E-5 6.045E-4 3.335E-3 5 58
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 2070 annotations before applied cutoff / 20974 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 endothelial Top 500 All endothelial Top 500 All Brain Map - Barres 3.596E-23 7.445E-20 6.114E-19 7.445E-20 24 496
2 endothelial Top 500 Cluster 0 endothelial Top 500 Cluster 0 Brain Map - Barres 4.876E-12 3.455E-9 2.838E-8 1.009E-8 10 128
3 54Dn SubClass 54Dn 1SK Top 500 All 54Dn SubClass 54Dn 1SK Top 500 All Brain Map - Allen iN 5.008E-12 3.455E-9 2.838E-8 1.037E-8 15 461
4 80Dn Top 500 All 80Dn Top 500 All Brain Map - Allen iN 1.335E-11 6.908E-9 5.673E-8 2.763E-8 15 494
5 80Dn SubClass 80Dn 1 Top 500 All 80Dn SubClass 80Dn 1 Top 500 All Brain Map - Allen iN 1.533E-10 5.288E-8 4.343E-7 3.173E-7 14 489
6 80Dn SubClass 80Dn 1 Top 500 Cluster 0 80Dn SubClass 80Dn 1 Top 500 Cluster 0 Brain Map - Allen iN 1.533E-10 5.288E-8 4.343E-7 3.173E-7 14 489
7 80Dn Top 500 Cluster 1 80Dn Top 500 Cluster 1 Brain Map - Allen iN 3.194E-10 9.445E-8 7.757E-7 6.612E-7 8 92
8 PCBC ratio ECTO blastocyst vs ECTO UCB CD34+Z cfr-2X-p05 ECTO blastocyst vs ECTO UCB CD34+Z-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 1.098E-9 2.842E-7 2.334E-6 2.274E-6 11 294
9 GSM605820 500 Myeloid Cells, DC.103+11b-.PolyIC.Lu, CD45 MHCII CD11c CD103 CD11b, Lung, avg-3 Immgen.org, GSE15907 1.763E-8 3.835E-6 3.150E-5 3.650E-5 11 384
10 Lungmap Mouse e16.5 Endothelial Top 500 Cluster 3 Mouse Lung E16.5 Endothelial top 500 c3 Lungmap Mouse Single Cell (Lungmap.net) 1.853E-8 3.835E-6 3.150E-5 3.835E-5 6 57
11 endothelial SubClass endothelial all Top 500 All endothelial SubClass endothelial all Top 500 All Brain Map - Barres 2.046E-8 3.851E-6 3.162E-5 4.236E-5 12 489
12 GSM854241 500 Myeloid Cells, DC.103+11b-.Lu, MHCII+ CD11c+ CD103+ CD11b, Lung, avg-2 Immgen.org, GSE15907 2.818E-8 4.587E-6 3.767E-5 5.834E-5 11 402
13 Lungmap Mouse e18.5 Epithelial (GSE52583) SubClass AT1 Top 500 Cluster 3 Mouse Lung E18.5 Epithelial AT1 c3 Lungmap Mouse Single Cell (Lungmap.net) 3.102E-8 4.587E-6 3.767E-5 6.422E-5 6 62
14 54Dn SubClass 54Dn 1SK Top 500 Cluster 0 54Dn SubClass 54Dn 1SK Top 500 Cluster 0 Brain Map - Allen iN 3.102E-8 4.587E-6 3.767E-5 6.422E-5 6 62
15 oligodendrocytes Top 500 Cluster 1 oligodendrocytes Top 500 Cluster 1 Brain Map - Barres 1.262E-7 1.741E-5 1.430E-4 2.612E-4 5 40
16 54Dn SubClass 54Dn 1 Top 500 Cluster 0 54Dn SubClass 54Dn 1 Top 500 Cluster 0 Brain Map - Allen iN 2.125E-7 2.444E-5 2.007E-4 4.398E-4 11 491
17 54Dn SubClass 54Dn 1 Top 500 All 54Dn SubClass 54Dn 1 Top 500 All Brain Map - Allen iN 2.125E-7 2.444E-5 2.007E-4 4.398E-4 11 491
18 54Dn Top 500 All 54Dn Top 500 All Brain Map - Allen iN 2.213E-7 2.444E-5 2.007E-4 4.581E-4 11 493
19 endothelial SubClass endothelial all Top 500 Cluster 3 endothelial SubClass endothelial all Top 500 Cluster 3 Brain Map - Barres 2.244E-7 2.444E-5 2.007E-4 4.644E-4 6 86
20 GSM854269 500 Myeloid Cells, DC.103-11b+24+.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24+, Lung, avg-2 Immgen.org, GSE15907 3.237E-7 3.351E-5 2.752E-4 6.701E-4 10 404
21 Lungmap Mouse e16.5 Myeloid SubClass Proliferative Myeloid Top 500 All Mouse Lung E16.5 Proliferative Myeloid top 500 Lungmap Mouse Single Cell (Lungmap.net) 3.465E-7 3.415E-5 2.805E-4 7.172E-4 10 407
22 Lungmap Mouse e18.5 Epithelial (GSE52583) SubClass AT1 Top 500 All Mouse Lung E18.5 Epithelial AT1 top 500 Lungmap Mouse Single Cell (Lungmap.net) 4.422E-7 4.161E-5 3.417E-4 9.154E-4 10 418
23 Lungmap Mouse e18.5 Epithelial (GSE52583) SubClass Bi-potential Top 500 Cluster 1 Mouse Lung E18.5 Epithelial BP c1 Lungmap Mouse Single Cell (Lungmap.net) 4.848E-7 4.261E-5 3.500E-4 1.004E-3 5 52
24 GSM538231 500 Myeloid Cells, DC.103+11b-.Lu, CD11chi CD11b low CD103+ MHCII+ SiglecF-, Lung, avg-3 Immgen.org, GSE15907 5.037E-7 4.261E-5 3.500E-4 1.043E-3 10 424
25 GSM538282 500 Myeloid Cells, MF.Lu, CD11chi CD11b- CD103- MHCII- SiglecF+, Lung, avg-3 Immgen.org, GSE15907 5.146E-7 4.261E-5 3.500E-4 1.065E-3 10 425
26 GSM777046 500 Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4 Immgen.org, GSE15907 6.771E-7 5.390E-5 4.427E-4 1.402E-3 10 438
27 Lungmap Mouse e16.5 Endothelial Top 500 All Mouse Lung E16.5 Endothelial top 500 Lungmap Mouse Single Cell (Lungmap.net) 7.979E-7 6.118E-5 5.024E-4 1.652E-3 10 446
28 gudmap kidney adult RenalCapsule k2 1000 kidney adult RenalCapsule k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.569E-6 1.160E-4 9.525E-4 3.247E-3 9 371
29 gudmap developingLowerUrinaryTract P1 bladder B 1000 k2 DevelopingLowerUrinaryTract P1 bladder B emap-30374 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.870E-6 1.334E-4 1.096E-3 3.870E-3 9 379
30 gudmap dev gonad e12.5 F VasAssocMesStromOvary Sma k4 1000 dev gonad e12.5 F VasAssocMesStromOvary Sma k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 2.044E-6 1.410E-4 1.158E-3 4.231E-3 6 125
31 Lungmap Mouse e18.5 Epithelial (GSE52583) Top 500 All Mouse Lung E18.5 Epithelial top 500 Lungmap Mouse Single Cell (Lungmap.net) 2.678E-6 1.788E-4 1.469E-3 5.543E-3 9 396
32 GSM605823 500 Myeloid Cells, DC.103-11b+.PolyIC.Lu, CD45 MHCII CD11c CD103 CD11b, Lung, avg-3 Immgen.org, GSE15907 3.484E-6 2.254E-4 1.851E-3 7.213E-3 9 409
33 GSM854302 500 Stromal Cells, Ep.MEChi.Th, CD45-EpCAm+Ly51-MHCIIhi, Thymus, avg-1 Immgen.org, GSE15907 3.625E-6 2.274E-4 1.868E-3 7.505E-3 9 411
34 GSM854271 500 Myeloid Cells, DC.103-11b+24-.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24-, Lung, avg-2 Immgen.org, GSE15907 3.846E-6 2.342E-4 1.923E-3 7.961E-3 9 414
35 GSM854309 500 Myeloid Cells, GN.Thio.PC, CD11b+ Ly6-G+, Peritoneal Cavity, avg-3 Immgen.org, GSE15907 3.999E-6 2.365E-4 1.943E-3 8.279E-3 9 416
36 GSM854338 500 Myeloid Cells, GN.Arth.SynF, CD11b+ Ly6-G+, Synovial Fluid, avg-3 Immgen.org, GSE15907 4.158E-6 2.391E-4 1.964E-3 8.607E-3 9 418
37 GSM605865 100 Myeloid Cells, MF.Thio5.II-480int.PC, CD115+ MHCII- F480int SiglecF- CD11c+, Peritoneal Cavity, avg-3 Immgen.org, GSE15907 4.471E-6 2.501E-4 2.054E-3 9.254E-3 5 81
38 GSM605862 500 Myeloid Cells, MF.Thio5.II-480hi.PC, CD115+ MHC II- F480hi Siglec F-, Peritoneal Cavity, avg-3 Immgen.org, GSE15907 6.410E-6 3.492E-4 2.868E-3 1.327E-2 9 441
39 gudmap dev gonad e11.5 M ReproVasc Flk k2 1000 dev gonad e11.5 M ReproVasc Flk k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 6.727E-6 3.567E-4 2.930E-3 1.392E-2 5 88
40 GSM777043 500 Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3 Immgen.org, GSE15907 6.894E-6 3.567E-4 2.930E-3 1.427E-2 9 445
41 54SK Top 500 Cluster 2 54SK Top 500 Cluster 2 Brain Map - Allen iN 7.230E-6 3.650E-4 2.998E-3 1.497E-2 3 13
42 GSM777067 500 Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2 Immgen.org, GSE15907 7.954E-6 3.920E-4 3.220E-3 1.646E-2 9 453
43 endothelial SubClass DCN-hi Top 500 All endothelial SubClass DCN-hi Top 500 All Brain Map - Barres 1.612E-5 7.625E-4 6.262E-3 3.337E-2 9 495
44 gudmap kidney adult GlomCapSys Tie2 k1 1000 kidney adult GlomCapSys Tie2 k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.621E-5 7.625E-4 6.262E-3 3.355E-2 7 270
45 26Dn SubClass 26Dn 2 Top 500 All 26Dn SubClass 26Dn 2 Top 500 All Brain Map - Allen iN 1.691E-5 7.780E-4 6.389E-3 3.501E-2 9 498
46 26Dn Top 500 Cluster 4 26Dn Top 500 Cluster 4 Brain Map - Allen iN 1.796E-5 8.081E-4 6.636E-3 3.717E-2 4 52
47 Lungmap Mouse e16.5 Myeloid SubClass Proliferative Myeloid Top 500 Cluster 4 Mouse Lung E16.5 Myeloid Proliferative Myeloid c4 Lungmap Mouse Single Cell (Lungmap.net) 2.418E-5 1.043E-3 8.565E-3
5.006E-2
 3 19
48 54Dn Top 500 Cluster 2 54Dn Top 500 Cluster 2 Brain Map - Allen iN 2.418E-5 1.043E-3 8.565E-3
5.006E-2
 3 19
49 PCBC ratio ECTO blastocyst vs ECTO amniotic fluid MSC cfr-2X-p05 ECTO blastocyst vs ECTO amniotic fluid MSC-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 2.565E-5 1.083E-3 8.898E-3
5.309E-2
 7 290
50 Lungmap Mouse e18.5 Epithelial (GSE52583) SubClass Bi-potential Top 500 All Mouse Lung E18.5 Epithelial Bi-potential top 500 Lungmap Mouse Single Cell (Lungmap.net) 2.619E-5 1.084E-3 8.905E-3
5.421E-2
 8 402
Show 45 more annotations

15: Computational [Display Chart] 272 annotations before applied cutoff / 9399 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 module 1 Genes in module 1 MSigDb: C4 - CM: Cancer Modules 7.229E-10 1.966E-7 1.216E-6 1.966E-7 15 361
2 module 3 Genes in module 3 MSigDb: C4 - CM: Cancer Modules 1.041E-7 1.415E-5 8.754E-5 2.831E-5 13 375
3 module 52 Genes in module 52 MSigDb: C4 - CM: Cancer Modules 3.761E-7 3.410E-5 2.109E-4 1.023E-4 13 419
4 module 2 Genes in module 2 MSigDb: C4 - CM: Cancer Modules 9.009E-7 6.126E-5 3.789E-4 2.451E-4 12 378
5 MORF NPM1 Neighborhood of NPM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood 1.956E-6 1.064E-4 6.581E-4 5.320E-4 8 153
6 MORF ACTG1 Neighborhood of ACTG1 MSigDb: C4 - CGN: Cancer Gene Neighborhood 9.134E-6 3.780E-4 2.338E-3 2.484E-3 7 134
7 module 118 Genes in module 118 MSigDb: C4 - CM: Cancer Modules 9.729E-6 3.780E-4 2.338E-3 2.646E-3 11 395
8 module 12 Genes in module 12 MSigDb: C4 - CM: Cancer Modules 2.158E-5 6.379E-4 3.945E-3 5.869E-3 10 351
9 module 164 Genes in module 164 MSigDb: C4 - CM: Cancer Modules 2.202E-5 6.379E-4 3.945E-3 5.990E-3 5 61
10 module 18 Genes in module 18 MSigDb: C4 - CM: Cancer Modules 2.458E-5 6.379E-4 3.945E-3 6.685E-3 11 436
11 MORF JUND Neighborhood of JUND MSigDb: C4 - CGN: Cancer Gene Neighborhood 2.580E-5 6.379E-4 3.945E-3 7.017E-3 5 63
12 module 151 Genes in module 151 MSigDb: C4 - CM: Cancer Modules 4.823E-5 1.093E-3 6.761E-3 1.312E-2 9 308
13 MORF EIF4A2 Neighborhood of EIF4A2 MSigDb: C4 - CGN: Cancer Gene Neighborhood 5.896E-5 1.234E-3 7.630E-3 1.604E-2 6 122
14 module 6 Genes in module 6 MSigDb: C4 - CM: Cancer Modules 7.603E-5 1.391E-3 8.604E-3 2.068E-2 10 407
15 module 114 Genes in module 114 MSigDb: C4 - CM: Cancer Modules 7.671E-5 1.391E-3 8.604E-3 2.087E-2 9 327
16 module 543 Genes in module 543 MSigDb: C4 - CM: Cancer Modules 1.089E-4 1.851E-3 1.145E-2 2.962E-2 3 17
17 module 223 Genes in module 223 MSigDb: C4 - CM: Cancer Modules 1.267E-4 2.027E-3 1.253E-2 3.445E-2 6 140
18 MORF UBE2I Neighborhood of UBE2I MSigDb: C4 - CGN: Cancer Gene Neighborhood 1.769E-4 2.673E-3 1.653E-2 4.811E-2 7 213
19 module 38 Genes in module 38 MSigDb: C4 - CM: Cancer Modules 1.911E-4 2.735E-3 1.692E-2
5.197E-2
 10 455
20 MORF TPT1 Neighborhood of TPT1 MSigDb: C4 - CGN: Cancer Gene Neighborhood 2.361E-4 3.211E-3 1.986E-2
6.421E-2
 5 100
21 GNF2 MSN Neighborhood of MSN MSigDb: C4 - CGN: Cancer Gene Neighborhood 3.152E-4 4.082E-3 2.525E-2
8.573E-2
 3 24
22 module 321 Genes in module 321 MSigDb: C4 - CM: Cancer Modules 3.378E-4 4.170E-3 2.579E-2
9.189E-2
 5 108
23 GCM NPM1 Neighborhood of NPM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood 3.526E-4 4.170E-3 2.579E-2
9.590E-2
 5 109
24 module 44 Genes in module 44 MSigDb: C4 - CM: Cancer Modules 3.770E-4 4.272E-3 2.642E-2
1.025E-1
 8 319
25 GCM ACTG1 Neighborhood of ACTG1 MSigDb: C4 - CGN: Cancer Gene Neighborhood 4.515E-4 4.912E-3 3.038E-2
1.228E-1
 5 115
26 module 5 Genes in module 5 MSigDb: C4 - CM: Cancer Modules 5.282E-4 5.526E-3 3.418E-2
1.437E-1
 9 423
27 GCM TPT1 Neighborhood of TPT1 MSigDb: C4 - CGN: Cancer Gene Neighborhood 5.941E-4 5.985E-3 3.702E-2
1.616E-1
 4 69
28 module 324 Genes in module 324 MSigDb: C4 - CM: Cancer Modules 8.180E-4 7.946E-3 4.915E-2
2.225E-1
 5 131
29 module 390 Genes in module 390 MSigDb: C4 - CM: Cancer Modules 8.548E-4 8.018E-3 4.959E-2
2.325E-1
 2 8
30 module 47 Genes in module 47 MSigDb: C4 - CM: Cancer Modules 1.281E-3 1.162E-2
7.184E-2
3.485E-1
 6 216
31 module 540 Genes in module 540 MSigDb: C4 - CM: Cancer Modules 1.364E-3 1.197E-2
7.402E-2
3.710E-1
 2 10
32 module 121 Genes in module 121 MSigDb: C4 - CM: Cancer Modules 2.201E-3 1.871E-2
1.157E-1
5.986E-1
 4 98
33 GCM APEX1 Neighborhood of APEX1 MSigDb: C4 - CGN: Cancer Gene Neighborhood 2.928E-3 2.413E-2
1.493E-1
7.964E-1
 4 106
34 MORF ANP32B Neighborhood of ANP32B MSigDb: C4 - CGN: Cancer Gene Neighborhood 3.169E-3 2.535E-2
1.568E-1
8.619E-1
 5 178
35 GNF2 EIF3S6 Neighborhood of EIF3S6 MSigDb: C4 - CGN: Cancer Gene Neighborhood 3.347E-3 2.601E-2
1.609E-1
9.104E-1
 4 110
36 module 191 Genes in module 191 MSigDb: C4 - CM: Cancer Modules 5.017E-3 3.791E-2
2.345E-1
1.000E0
 2 19
Show 31 more annotations

16: MicroRNA [Display Chart] 874 annotations before applied cutoff / 19844 genes in category

No results to display

17: Drug [Display Chart] 14326 annotations before applied cutoff / 22098 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000030956 AC1L1KMJ Stitch 3.795E-12 5.437E-8 5.517E-7 5.437E-8 15 476
2 D001761 Bleomycin CTD 1.037E-11 7.431E-8 7.541E-7 1.486E-7 14 420
3 C010063 carbonyl sulfide CTD 1.516E-10 7.239E-7 7.346E-6 2.172E-6 9 134
4 C430898 AGN 194204 CTD 3.475E-10 1.235E-6 1.254E-5 4.978E-6 9 147
5 C059765 amphotericin B, deoxycholate drug combination CTD 4.312E-10 1.235E-6 1.254E-5 6.177E-6 12 365
6 C042577 diallyl trisulfide CTD 1.473E-9 3.516E-6 3.568E-5 2.110E-5 8 117
7 CID011214849 2 IgY Stitch 2.085E-9 4.268E-6 4.331E-5 2.988E-5 4 7
8 D002235 Carbofuran CTD 4.141E-9 7.043E-6 7.146E-5 5.932E-5 7 84
9 CID000006124 dimethylnitrosamine Stitch 4.424E-9 7.043E-6 7.146E-5 6.338E-5 9 196
10 MESH:D011471/D011794-T Prostatic Neoplasms affected by Quercetin CTD Therapeutic 1.736E-8 2.488E-5 2.524E-4 2.488E-4 7 103
11 1598 UP Colchicine [64-86-8]; Up 200; 10uM; HL60; HG-U133A Broad Institute CMAP 2.941E-8 3.831E-5 3.887E-4 4.214E-4 8 171
12 D016559 Tacrolimus CTD 3.719E-8 4.440E-5 4.505E-4 5.327E-4 10 337
13 D011692 Puromycin Aminonucleoside CTD 7.223E-8 7.960E-5 8.077E-4 1.035E-3 8 192
14 MESH:D011471/D020849-T Prostatic Neoplasms affected by Raloxifene CTD Therapeutic 8.518E-8 8.413E-5 8.536E-4 1.220E-3 6 77
15 D006820 Hyaluronic Acid CTD 8.808E-8 8.413E-5 8.536E-4 1.262E-3 8 197
16 MESH:D011471/C430898-T Prostatic Neoplasms affected by AGN 194204 CTD Therapeutic 1.064E-7 9.460E-5 9.600E-4 1.524E-3 4 16
17 C043211 carvedilol CTD 1.130E-7 9.460E-5 9.600E-4 1.619E-3 7 135
18 MESH:D011471/C017947-M Prostatic Neoplasms affected by sodium arsenite CTD Marker 1.189E-7 9.460E-5 9.600E-4 1.703E-3 7 136
19 MESH:D011471/C006632-T Prostatic Neoplasms affected by arsenic trioxide CTD Therapeutic 1.314E-7 9.906E-5 1.005E-3 1.882E-3 7 138
20 D017258 Medroxyprogesterone Acetate CTD 1.452E-7 1.040E-4 1.056E-3 2.081E-3 10 390
21 C457499 2-chloro-5-nitrobenzanilide CTD 1.900E-7 1.296E-4 1.315E-3 2.722E-3 6 88
22 C063002 2,3-dimethoxy-1,4-naphthoquinone CTD 2.657E-7 1.671E-4 1.695E-3 3.807E-3 7 153
23 C011559 tributyltin CTD 2.682E-7 1.671E-4 1.695E-3 3.842E-3 9 316
24 MESH:D011471/D004317-T Prostatic Neoplasms affected by Doxorubicin CTD Therapeutic 2.817E-7 1.682E-4 1.706E-3 4.036E-3 6 94
25 C030370 2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone CTD 2.981E-7 1.690E-4 1.715E-3 4.271E-3 9 320
26 C051786 metolachlor CTD 3.075E-7 1.690E-4 1.715E-3 4.405E-3 5 50
27 D004298 Dopamine CTD 3.185E-7 1.690E-4 1.715E-3 4.562E-3 8 233
28 D008345 Manganese CTD 4.497E-7 2.301E-4 2.335E-3 6.443E-3 10 441
29 CID000005711 Y-27632 Stitch 4.883E-7 2.412E-4 2.448E-3 6.996E-3 10 445
30 C057862 cyanoginosin LR CTD 5.944E-7 2.733E-4 2.773E-3 8.516E-3 8 253
31 MESH:D001943/D013749-M Breast Neoplasms affected by Tetrachlorodibenzodioxin CTD Marker 6.105E-7 2.733E-4 2.773E-3 8.746E-3 7 173
32 1122 UP cytochalasin B; Up 200; 20.8uM; MCF7; HT HG-U133A EA Broad Institute CMAP 6.105E-7 2.733E-4 2.773E-3 8.746E-3 7 173
33 MESH:D011471/D017239-T Prostatic Neoplasms affected by Paclitaxel CTD Therapeutic 6.534E-7 2.837E-4 2.878E-3 9.361E-3 5 58
34 2690 UP thioridazine hydrochloride; Up 200; 10uM; HL60; HT HG-U133A Broad Institute CMAP 7.121E-7 2.916E-4 2.959E-3 1.020E-2 7 177
35 D018684 Glycine Agents CTD 7.123E-7 2.916E-4 2.959E-3 1.021E-2 5 59
36 CID000024759 hyaluronan Stitch 7.961E-7 3.168E-4 3.215E-3 1.141E-2 8 263
37 C010327 salinomycin CTD 8.587E-7 3.325E-4 3.374E-3 1.230E-2 7 182
38 MESH:D011471/D004958-M Prostatic Neoplasms affected by Estradiol CTD Marker 9.935E-7 3.746E-4 3.801E-3 1.423E-2 7 186
39 C064769 N-acetylsphingosine CTD 1.160E-6 4.261E-4 4.324E-3 1.662E-2 5 65
40 D003609 Dactinomycin CTD 1.343E-6 4.811E-4 4.882E-3 1.924E-2 8 282
41 C037219 quinoline CTD 1.454E-6 5.055E-4 5.129E-3 2.083E-2 5 68
42 D014302 Trinitrobenzenesulfonic Acid CTD 1.482E-6 5.055E-4 5.129E-3 2.123E-2 9 388
43 C028904 isoproturon CTD 1.681E-6 5.474E-4 5.554E-3 2.408E-2 5 70
44 CID003359490 AC1MNW2N Stitch 1.681E-6 5.474E-4 5.554E-3 2.408E-2 5 70
45 CID000115167 1-azidopyrene Stitch 1.832E-6 5.834E-4 5.919E-3 2.625E-2 3 9
46 MESH:D001943/D004317-T Breast Neoplasms affected by Doxorubicin CTD Therapeutic 2.073E-6 6.455E-4 6.550E-3 2.969E-2 5 73
47 C008493 methylselenic acid CTD 2.194E-6 6.682E-4 6.780E-3 3.144E-2 9 407
48 D016685 Mitomycin CTD 2.239E-6 6.682E-4 6.780E-3 3.207E-2 9 408
49 D003994 Bucladesine CTD 2.408E-6 7.041E-4 7.144E-3 3.450E-2 8 305
50 CID000001445 16,16-dimethyl prostaglandin E2 Stitch 2.608E-6 7.446E-4 7.556E-3 3.737E-2 4 34
Show 45 more annotations

18: Disease [Display Chart] 1788 annotations before applied cutoff / 16150 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 umls:C1709246 Non-Neoplastic Disorder DisGeNET BeFree 1.294E-9 8.923E-7 7.197E-6 2.313E-6 14 461
2 umls:C0338106 Adenocarcinoma of colon DisGeNET Curated 1.349E-9 8.923E-7 7.197E-6 2.413E-6 11 240
3 umls:C0027626 Neoplasm Invasiveness DisGeNET Curated 1.497E-9 8.923E-7 7.197E-6 2.677E-6 9 132
4 umls:C1621958 Glioblastoma Multiforme DisGeNET BeFree 6.478E-9 2.896E-6 2.336E-5 1.158E-5 13 434
5 umls:C0346957 Disseminated Malignant Neoplasm DisGeNET BeFree 9.132E-9 3.266E-6 2.634E-5 1.633E-5 9 162
6 umls:C1134719 Invasive Ductal Breast Carcinoma DisGeNET Curated 1.241E-8 3.698E-6 2.983E-5 2.219E-5 10 228
7 umls:C0025286 Meningioma DisGeNET Curated 1.629E-8 4.161E-6 3.357E-5 2.913E-5 12 383
8 umls:C0334579 Anaplastic astrocytoma DisGeNET Curated 4.404E-8 9.843E-6 7.939E-5 7.874E-5 8 137
9 umls:C3539878 Triple Negative Breast Neoplasms DisGeNET BeFree 1.104E-7 2.193E-5 1.769E-4 1.974E-4 12 456
10 umls:C0022548 Keloid DisGeNET Curated 1.950E-7 3.325E-5 2.682E-4 3.487E-4 8 166
11 umls:C0024232 Lymphatic Metastasis DisGeNET Curated 2.046E-7 3.325E-5 2.682E-4 3.658E-4 7 112
12 umls:C1800706 Idiopathic Pulmonary Fibrosis DisGeNET Curated 3.255E-7 4.850E-5 3.912E-4 5.820E-4 10 323
13 umls:C0032927 Precancerous Conditions DisGeNET Curated 4.498E-7 6.186E-5 4.990E-4 8.042E-4 11 423
14 umls:C0007138 Carcinoma, Transitional Cell DisGeNET Curated 9.699E-7 1.155E-4 9.319E-4 1.734E-3 10 364
15 umls:C0007124 Noninfiltrating Intraductal Carcinoma DisGeNET Curated 1.010E-6 1.155E-4 9.319E-4 1.806E-3 9 281
16 umls:C0035335 Retinoblastoma DisGeNET Curated 1.095E-6 1.155E-4 9.319E-4 1.958E-3 11 463
17 umls:C0151546 Oral Cavity Carcinoma DisGeNET BeFree 1.098E-6 1.155E-4 9.319E-4 1.964E-3 6 90
18 umls:C0856169 Endothelial dysfunction DisGeNET BeFree 1.441E-6 1.431E-4 1.154E-3 2.576E-3 8 216
19 umls:C0024668 Mammary Neoplasms, Experimental DisGeNET Curated 1.624E-6 1.528E-4 1.232E-3 2.903E-3 7 152
20 umls:C0038356 Stomach Neoplasms DisGeNET Curated 1.902E-6 1.700E-4 1.372E-3 3.401E-3 11 490
21 umls:C0024117 Chronic Obstructive Airway Disease DisGeNET Curated 2.182E-6 1.858E-4 1.499E-3 3.902E-3 11 497
22 umls:C0034069 Pulmonary Fibrosis DisGeNET Curated 2.731E-6 2.220E-4 1.791E-3 4.884E-3 9 317
23 umls:C0206682 Follicular thyroid carcinoma DisGeNET Curated 2.922E-6 2.272E-4 1.832E-3 5.225E-3 7 166
24 umls:C0239946 Fibrosis, Liver DisGeNET BeFree 3.520E-6 2.623E-4 2.116E-3 6.294E-3 9 327
25 umls:C0262659 Vagina Carcinoma DisGeNET BeFree 4.238E-6 2.914E-4 2.351E-3 7.577E-3 3 9
26 umls:C0162291 Retinal ischemia DisGeNET BeFree 4.238E-6 2.914E-4 2.351E-3 7.577E-3 3 9
27 umls:C1449563 Cardiomyopathy, Familial Idiopathic DisGeNET Curated 4.469E-6 2.960E-4 2.387E-3 7.991E-3 7 177
28 umls:C0007133 Carcinoma, Papillary DisGeNET BeFree 6.196E-6 3.956E-4 3.191E-3 1.108E-2 7 186
29 umls:C0030524 Paratuberculosis DisGeNET Curated 7.847E-6 4.838E-4 3.903E-3 1.403E-2 4 34
30 umls:C0282612 Prostatic Intraepithelial Neoplasias DisGeNET Curated 8.563E-6 5.103E-4 4.117E-3 1.531E-2 6 128
31 umls:C0853879 Invasive breast carcinoma DisGeNET BeFree 9.355E-6 5.396E-4 4.352E-3 1.673E-2 9 369
32 umls:C0153690 Secondary malignant neoplasm of bone DisGeNET BeFree 1.174E-5 6.561E-4 5.292E-3 2.100E-2 8 287
33 umls:C0086692 Benign Neoplasm DisGeNET BeFree 1.246E-5 6.753E-4 5.447E-3 2.228E-2 7 207
34 umls:C0026918 Mycobacterium Infections DisGeNET Curated 1.507E-5 7.923E-4 6.391E-3 2.694E-2 5 83
35 umls:C0346153 Breast Cancer, Familial DisGeNET Curated 1.816E-5 9.277E-4 7.483E-3 3.247E-2 6 146
36 umls:C0238461 Anaplastic thyroid carcinoma DisGeNET Curated 2.017E-5 1.002E-3 8.082E-3 3.607E-2 7 223
37 umls:C0751690 Malignant Peripheral Nerve Sheath Tumor DisGeNET BeFree 2.198E-5 1.052E-3 8.483E-3 3.930E-2 6 151
38 umls:C1168327 High-Grade Prostatic Intraepithelial Neoplasia DisGeNET BeFree 2.235E-5 1.052E-3 8.483E-3 3.996E-2 5 90
39 umls:C0015695 Fatty Liver DisGeNET Curated 2.404E-5 1.098E-3 8.858E-3 4.299E-2 8 317
40 umls:C1334274 Invasive Carcinoma DisGeNET BeFree 2.457E-5 1.098E-3 8.858E-3 4.392E-2 6 154
41 umls:C0220641 Lip and Oral Cavity Carcinoma DisGeNET BeFree 2.566E-5 1.119E-3 9.026E-3 4.588E-2 9 419
42 umls:C0741923 cardiac event DisGeNET BeFree 2.669E-5 1.136E-3 9.166E-3 4.773E-2 4 46
43 umls:C0007112 Adenocarcinoma of prostate DisGeNET BeFree 2.942E-5 1.223E-3 9.867E-3
5.260E-2
 6 159
44 umls:C0017075 Ganglioneuroma DisGeNET BeFree 3.165E-5 1.286E-3 1.037E-2
5.659E-2
 4 48
45 umls:C0278883 Metastatic melanoma DisGeNET BeFree 3.416E-5 1.357E-3 1.095E-2
6.108E-2
 8 333
46 umls:C0494165 Secondary malignant neoplasm of liver DisGeNET BeFree 4.638E-5 1.803E-3 1.454E-2
8.292E-2
 9 452
47 umls:C0476073 Papillary neoplasm DisGeNET BeFree 4.759E-5 1.810E-3 1.460E-2
8.509E-2
 3 19
48 umls:C0007621 Neoplastic Cell Transformation DisGeNET Curated 4.921E-5 1.833E-3 1.479E-2
8.799E-2
 5 106
49 umls:C0877430 Asthma chronic DisGeNET BeFree 5.583E-5 2.011E-3 1.622E-2
9.983E-2
 3 20
50 umls:C2931852 Clear-cell metastatic renal cell carcinoma DisGeNET BeFree 5.624E-5 2.011E-3 1.622E-2
1.006E-1
 5 109
Show 45 more annotations