Toppgene analysis for aggregated_1964_log, IC19, positive side

Go To Start Page
Input Parameters [Show Detail]
Training Results [Expand All] [Download All] [Sparse Matrix]
Display pValues and Scores as Table row limit

1: GO: Molecular Function [Display Chart] 497 annotations before applied cutoff / 18819 genes in category

No results to display

2: GO: Biological Process [Display Chart] 2721 annotations before applied cutoff / 18785 genes in category

No results to display

3: GO: Cellular Component [Display Chart] 296 annotations before applied cutoff / 19172 genes in category

No results to display

4: Human Phenotype [Display Chart] 506 annotations before applied cutoff / 4410 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0000682 Abnormality of dental enamel 5.102E-5 2.582E-2
1.757E-1
 2.582E-2 2 2

5: Mouse Phenotype [Display Chart] 2412 annotations before applied cutoff / 9299 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0006049 semilunar valve regurgitation 1.348E-5 3.252E-2
2.721E-1
 3.252E-2 4 17

6: Domain [Display Chart] 1049 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR014797 CKK domain InterPro 1.727E-4 2.264E-2
1.706E-1
1.812E-1
 2 3
2 PF08683 CAMSAP CKK Pfam 1.727E-4 2.264E-2
1.706E-1
1.812E-1
 2 3
3 IPR032940 CAMSAP InterPro 1.727E-4 2.264E-2
1.706E-1
1.812E-1
 2 3
4 PS51508 CKK PROSITE 1.727E-4 2.264E-2
1.706E-1
1.812E-1
 2 3
5 IPR011033 PRC barrel-like InterPro 1.727E-4 2.264E-2
1.706E-1
1.812E-1
 2 3
6 IPR031372 CAMSAP CC1 InterPro 1.727E-4 2.264E-2
1.706E-1
1.812E-1
 2 3
7 SM01051 CAMSAP CKK SMART 1.727E-4 2.264E-2
1.706E-1
1.812E-1
 2 3
8 PF17095 CAMSAP CC1 Pfam 1.727E-4 2.264E-2
1.706E-1
1.812E-1
 2 3
9 SM00231 FA58C SMART 5.236E-4 4.577E-2
3.448E-1
5.492E-1
 3 21
10 PS01286 FA58C 2 PROSITE 5.236E-4 4.577E-2
3.448E-1
5.492E-1
 3 21
11 PS50022 FA58C 3 PROSITE 5.236E-4 4.577E-2
3.448E-1
5.492E-1
 3 21
12 PS01285 FA58C 1 PROSITE 5.236E-4 4.577E-2
3.448E-1
5.492E-1
 3 21
Show 7 more annotations

7: Pathway [Display Chart] 670 annotations before applied cutoff / 10916 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 P00018 EGF receptor signaling pathway PantherDB 1.184E-4 4.484E-2
3.177E-1
7.930E-2
 6 111
2 83115 Bladder cancer BioSystems: KEGG 1.338E-4 4.484E-2
3.177E-1
8.968E-2
 4 38

8: Pubmed [Display Chart] 21977 annotations before applied cutoff / 51853 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 19199708 Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Pubmed 2.989E-7 3.879E-3 4.102E-2 6.570E-3 10 414
2 22190034 Global landscape of HIV-human protein complexes. Pubmed 7.329E-7 3.879E-3 4.102E-2 1.611E-2 10 457
3 21423176 Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for Ã?-Pix in negative regulation of focal adhesion maturation. Pubmed 1.610E-6 3.879E-3 4.102E-2 3.538E-2 8 286
4 26389662 Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis. Pubmed 2.253E-6 3.879E-3 4.102E-2 4.952E-2 7 209
5 12878157 Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis. Pubmed 2.548E-6 3.879E-3 4.102E-2
5.600E-2
 4 34
6 16303743 Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. Pubmed 3.829E-6 3.879E-3 4.102E-2
8.414E-2
 9 430
7 20453000:gr A Large-scale genetic association study of esophageal adenocarcinoma risk. GeneRIF 7.248E-6 3.879E-3 4.102E-2
1.593E-1
 8 351
8 20453000 A Large-scale genetic association study of esophageal adenocarcinoma risk. Pubmed 7.248E-6 3.879E-3 4.102E-2
1.593E-1
 8 351
9 25730904 Knockdown of GALNT1 suppresses malignant phenotype of hepatocellular carcinoma by suppressing EGFR signaling. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
10 15302576:gr DU145 human prostate carcinoma invasiveness is modulated by urokinase receptor (uPAR) downstream of epidermal growth factor receptor (EGFR) signaling. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
11 24675463 Temozolomide resistance in glioblastoma cells occurs partly through epidermal growth factor receptor-mediated induction of connexin 43. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
12 15702432 Classic and non-classic progesterone receptors are both expressed in human spermatozoa. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
13 12787920 Human tissue factor pathway inhibitor-2 does not bind or inhibit activated matrix metalloproteinase-1. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
14 18586252:gr High glucose and interferon gamma synergistically stimulate MMP-1 expression in U937 macrophages by increasing transcription factor STAT1 activity. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
15 21896743 Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
16 14730602 Retinoblastoma suppression of matrix metalloproteinase 1, but not interleukin-6, through a p38-dependent pathway in rheumatoid arthritis synovial fibroblasts. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
17 25837250 Soluble Urokinase Receptor Is Released Selectively by Glioblastoma Cells That Express Epidermal Growth Factor Receptor Variant III and Promotes Tumor Cell Migration and Invasion. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
18 16803894:gr Suppression of the ligand-mediated down-regulation of epidermal growth factor receptor by Ymer, a novel tyrosine-phosphorylated and ubiquitinated protein. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
19 14730602:gr Retinoblastoma suppression of matrix metalloproteinase 1, but not interleukin-6, through a p38-dependent pathway in rheumatoid arthritis synovial fibroblasts. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
20 22855500:gr Hepatitis C virus induces epidermal growth factor receptor activation via CD81 binding for viral internalization and entry. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
21 18586252 High glucose and interferon gamma synergistically stimulate MMP-1 expression in U937 macrophages by increasing transcription factor STAT1 activity. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
22 22611165:gr Epidermal growth factor regulates connexin 43 in the human epididymis: role of gap junctions in azoospermia. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
23 16306221 The BTB domain of the nuclear matrix protein NRP/B is required for neurite outgrowth. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
24 21440529:gr ERK/MAPK pathways play critical roles in EGFR ligands-induced MMP1 expression. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
25 20538600 Pgrmc1 (progesterone receptor membrane component 1) associates with epidermal growth factor receptor and regulates erlotinib sensitivity. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
26 23172893 Proteomic analysis of temporally stimulated ovarian cancer cells for biomarker discovery. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
27 15302576 DU145 human prostate carcinoma invasiveness is modulated by urokinase receptor (uPAR) downstream of epidermal growth factor receptor (EGFR) signaling. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
28 16803894 Suppression of the ligand-mediated down-regulation of epidermal growth factor receptor by Ymer, a novel tyrosine-phosphorylated and ubiquitinated protein. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
29 20219323 Astaxanthin attenuates the UVA-induced up-regulation of matrix-metalloproteinase-1 and skin fibroblast elastase in human dermal fibroblasts. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
30 10574929 The novel kinase peptidylglycine alpha-amidating monooxygenase cytosolic interactor protein 2 interacts with the cytosolic routing determinants of the peptide processing enzyme peptidylglycine alpha-amidating monooxygenase. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
31 12787920:gr Human tissue factor pathway inhibitor-2 does not bind or inhibit activated matrix metalloproteinase-1. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
32 23219092:gr Extracellular epimorphin modulates epidermal differentiation signals mediated by epidermal growth factor receptor. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
33 20573687:gr Signaling from the secretory granule to the nucleus: Uhmk1 and PAM. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
34 17576813:gr BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
35 25758528 RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
36 23172893:gr Proteomic analysis of temporally stimulated ovarian cancer cells for biomarker discovery. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
37 15702432:gr Classic and non-classic progesterone receptors are both expressed in human spermatozoa. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
38 22855500 Hepatitis C virus induces epidermal growth factor receptor activation via CD81 binding for viral internalization and entry. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
39 9705155 Cloning and tissue expression of two putative steroid membrane receptors. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
40 21896743:gr Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
41 21440529 ERK/MAPK pathways play critical roles in EGFR ligands-induced MMP1 expression. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
42 23793472 Expression patterns of progesterone receptor membrane components 1 and 2 in endometria from women with and without endometriosis. Pubmed 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
43 20538600:gr Pgrmc1 (progesterone receptor membrane component 1) associates with epidermal growth factor receptor and regulates erlotinib sensitivity. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
44 20219323:gr Astaxanthin attenuates the UVA-induced up-regulation of matrix-metalloproteinase-1 and skin fibroblast elastase in human dermal fibroblasts. GeneRIF 7.766E-6 3.879E-3 4.102E-2
1.707E-1
 2 2
45 15164053 DNA sequence and analysis of human chromosome 9. Pubmed 1.061E-5 5.183E-3
5.481E-2
2.332E-1
 8 370
46 15588985 Substrate-trapping techniques in the identification of cellular PTP targets. Pubmed 1.222E-5 5.840E-3
6.175E-2
2.686E-1
 4 50
47 22487523:gr Invasive markers identified by gene expression profiling in pancreatic cancer. GeneRIF 2.325E-5 6.637E-3
7.018E-2
5.111E-1
 2 3
48 19480010:gr Urokinase receptor, MMP-1 and MMP-9 are markers to differentiate prognosis, adenoma and carcinoma in thyroid malignancies. GeneRIF 2.325E-5 6.637E-3
7.018E-2
5.111E-1
 2 3
49 23970345 Progesterone protects ovarian cancer cells from cisplatin-induced inhibitory effects through progesterone receptor membrane component 1/2 as well as AKT signaling. Pubmed 2.325E-5 6.637E-3
7.018E-2
5.111E-1
 2 3
50 20732323:gr GPR48-Induced keratinocyte proliferation occurs through HB-EGF mediated EGFR transactivation. GeneRIF 2.325E-5 6.637E-3
7.018E-2
5.111E-1
 2 3
Show 45 more annotations

9: Interaction [Display Chart] 3500 annotations before applied cutoff / 16534 genes in category

No results to display

10: Cytoband [Display Chart] 131 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 9p24.1 9p24.1 1.353E-5 1.773E-3 9.673E-3 1.773E-3 4 35
2 5q14 5q14 7.547E-4 4.943E-2
2.697E-1
9.886E-2
 2 10
3 10q25.2 10q25.2 2.798E-3 4.948E-2
2.700E-1
3.666E-1
 2 19
4 2q37.1-q37.2 2q37.1-q37.2 4.155E-3 4.948E-2
2.700E-1
5.442E-1
 1 1
5 7q31.1-q31.33 7q31.1-q31.33 4.155E-3 4.948E-2
2.700E-1
5.442E-1
 1 1
6 5q14-q21 5q14-q21 4.155E-3 4.948E-2
2.700E-1
5.442E-1
 1 1
7 7q21-q31 7q21-q31 4.155E-3 4.948E-2
2.700E-1
5.442E-1
 1 1
8 13q31.2-q32.3 13q31.2-q32.3 4.155E-3 4.948E-2
2.700E-1
5.442E-1
 1 1
9 10p12.3 10p12.3 4.155E-3 4.948E-2
2.700E-1
5.442E-1
 1 1
10 6q21-q23.2 6q21-q23.2 4.155E-3 4.948E-2
2.700E-1
5.442E-1
 1 1
11 11p14-p13 11p14-p13 4.155E-3 4.948E-2
2.700E-1
5.442E-1
 1 1
Show 6 more annotations

11: Transcription Factor Binding Site [Display Chart] 412 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 81 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1282 Membrane associated progesterone receptor family genenames.org 1.317E-4 1.067E-2
5.310E-2
 1.067E-2 2 4

13: Coexpression [Display Chart] 6051 annotations before applied cutoff / 21867 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M4665 Genes down-regulated in glomeruli of kidneys from patients with diabetic nephropathy (type 2 diabetes mellitus). MSigDB C2: CGP Curated Gene Sets (v5.1) 1.214E-16 7.348E-13 6.823E-12 7.348E-13 25 434
2 M19541 Genes commonly down-regulated in human alveolar rhabdomyosarcoma (ARMS) and its mouse model overexpressing PAX3-FOXO1 [GeneID=5077;2308] fusion. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.598E-15 9.632E-12 8.943E-11 2.177E-11 23 408
3 M9192 Genes down-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.775E-15 9.632E-12 8.943E-11 2.890E-11 24 460
4 M7363 Genes up-regulated in MCF7 cells (breast cancer) under hypoxia conditions. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.629E-9 2.465E-6 2.289E-5 9.859E-6 12 171
5 M5930 Genes defining epithelial-mesenchymal transition, as in wound healing, fibrosis and metastasis. MSigDB H: Hallmark Gene Sets (v5.1) 9.611E-9 1.163E-5 1.080E-4 5.816E-5 12 200
6 M9197 Genes up-regulated in MCF7 cells (breast cancer) treated with hypoxia mimetic DMOG [PubChem=3080614]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.626E-8 1.640E-5 1.522E-4 9.838E-5 10 130
7 M6189 Genes down-regulated in MCF7 cells (breast cancer) after knockdown of both HIF1A and HIF2A [GeneID=3091;2034] by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.107E-8 2.686E-5 2.494E-4 1.880E-4 9 104
8 M2123 Up-regulated genes in the cancer gene signature, representing a gene signature of cellular transformation. MSigDB C2: CGP Curated Gene Sets (v5.1) 7.927E-8 5.996E-5 5.567E-4 4.796E-4 12 242
9 M13522 Common down-regulated transcripts in fibroblasts expressing either XP/CS or TDD mutant forms of ERCC3 [GeneID=2071], after UVC irradiation. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.420E-7 8.942E-5 8.303E-4 8.594E-4 16 483
10 M8729 Genes whose expression peaked at 480 min after stimulation of HeLa cells with EGF [GeneID=1950]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.478E-7 8.942E-5 8.303E-4 8.942E-4 10 164
11 M2122 Genes correlated with mesenchymal type of glioblastoma multiforme tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.154E-7 1.185E-4 1.100E-3 1.303E-3 11 216
12 M4008 Genes which best discriminate between two groups of breast cancer according to the status of ESR1 and AR [GeneID=2099;367]: apocrine (ESR1- AR+) and luminal (ESR1+ AR+). MSigDB C2: CGP Curated Gene Sets (v5.1) 2.804E-7 1.414E-4 1.313E-3 1.697E-3 13 326
13 M14507 Genes down-regulated in luminal-like breast cancer cell lines compared to the basal-like ones. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.693E-7 1.719E-4 1.596E-3 2.235E-3 15 454
14 M3898 Genes down-regulated in NHEK cells (normal epidermal keratinocytes) after UVB irradiation. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.478E-7 3.496E-4 3.246E-3 5.130E-3 15 485
15 M5073 Genes down-regulated in comparison of memory CD8 T cells versus naive CD8 T cells. MSigDB C7: Immunologic Signatures (v5.1) 9.243E-7 3.496E-4 3.246E-3 5.593E-3 10 200
16 M6157 Genes down-regulated in monocyte-derived macrophages: no priming versus primed by IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v5.1) 9.243E-7 3.496E-4 3.246E-3 5.593E-3 10 200
17 M2293 Genes down-regulated in ES (embryonic stem cells) with defficient SUZ12 [GeneID=23512]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.326E-6 4.719E-4 4.382E-3 8.022E-3 12 315
18 M5547 Age up-regulated genes in the human frontal cortex. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.456E-6 4.893E-4 4.543E-3 8.807E-3 11 262
19 M15835 Genes down-regulated SUM44/LCCTam cells (breast cancer) resistant to 4-hydroxytamoxifen [PubChem=63062] relative to the parental SUM44 cells sensitive to the drug. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.188E-6 6.969E-4 6.471E-3 1.324E-2 10 220
20 M16114 Genes down-regulated in HFK cells (primary keratinocytes) in response to UVB irradiation. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.445E-6 7.141E-4 6.630E-3 1.479E-2 5 33
21 M2513 Genes down-regulated in MCF7 cells (breast cancer) after knockdown of HIF1A [GeneID=3091] by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.478E-6 7.141E-4 6.630E-3 1.500E-2 7 91
22 M3804 Genes up-regulated in normal hematopoietic progenitors by RUNX1-RUNX1T1 [GeneID=861;862] fusion. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.124E-6 1.097E-3 1.019E-2 2.496E-2 9 185
23 M2803 Genes down-regulated in primary keratinocytes from RB1 and RBL2 [Gene ID=5925, 5934] skin specific knockout mice. MSigDB C6: Oncogenic Signatures (v5.1) 4.170E-6 1.097E-3 1.019E-2 2.523E-2 8 139
24 M2025 Genes down-regulated in mesenchymal stem cells during early phase of adipogenesis, defined as days 1 to 5 of culturing with adipogenic hormones. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.034E-6 1.269E-3 1.179E-2 3.046E-2 5 38
25 M14136 Genes down-regulated early in HMEC cells (mammary epithelium) during acinar development in vitro. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.629E-6 1.362E-3 1.265E-2 3.406E-2 3 6
26 M2721 Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] MCF-7 cells (breast cancer) and long-term adapted for estrogen-independent growth. MSigDB C6: Oncogenic Signatures (v5.1) 6.596E-6 1.516E-3 1.407E-2 3.991E-2 9 196
27 GSE36078 UNTREATED VS AD5 INF MOUSE LUNG DC DN Genes down-regulated in CD11c+ monocytes: control versus HAdv5 infection. MSigDB C7: Immunologic Signatures (v5.1) 7.766E-6 1.516E-3 1.407E-2 4.699E-2 9 200
28 M6435 Genes up-regulated in NKT cells versus B2 B lymphocytes. MSigDB C7: Immunologic Signatures (v5.1) 7.766E-6 1.516E-3 1.407E-2 4.699E-2 9 200
29 GSE43955 1H VS 20H ACT CD4 TCELL WITH TGFB IL6 DN Genes down-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 1h versus 20h. MSigDB C7: Immunologic Signatures (v5.1) 7.766E-6 1.516E-3 1.407E-2 4.699E-2 9 200
30 GSE29164 DAY3 VS DAY7 UNTREATED MELANOMA DN Genes down-regulated in untreated B16 melanoma: day 3 versus day 7. MSigDB C7: Immunologic Signatures (v5.1) 7.766E-6 1.516E-3 1.407E-2 4.699E-2 9 200
31 GSE28726 NAIVE VS ACTIVATED NKTCELL DN Genes down-regulated in NKT cells: naïve versus activated. MSigDB C7: Immunologic Signatures (v5.1) 7.766E-6 1.516E-3 1.407E-2 4.699E-2 9 200
32 M863 Myb-regulated genes in MCF7 (breast cancer) and lung epithelial cell lines overexpressing MYBL2, MYBL1 or MYB [GeneID=4605;4603;4602]. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.287E-6 1.756E-3 1.631E-2
5.620E-2
 11 318
33 M12138 Genes up-regulated in erythroid lineage cells by RUNX1-RUNX1T1 [GeneID=861;862] fusion . MSigDB C2: CGP Curated Gene Sets (v5.1) 1.024E-5 1.877E-3 1.743E-2
6.194E-2
 8 157
34 M12085 Genes up-regulated by RUNX1-RUNX1T1 [GeneID=861;862] fusion protein in normal hematopoietic progenitors; their expression was sustained in subsequently developing erythroid lineage. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.055E-5 1.878E-3 1.743E-2
6.384E-2
 5 44
35 M14973 Genes up-regulated in U2OS cells (osteosarcoma) upon knockdown of HDAC1 [GeneID=3065] by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.160E-5 2.005E-3 1.861E-2
7.016E-2
 13 457
36 M9814 Genes down-regulated in poorly differentiated thyroid carcinoma (PDTC) compared to anaplastic thyroid carcinoma (ATC). MSigDB C2: CGP Curated Gene Sets (v5.1) 1.233E-5 2.073E-3 1.925E-2
7.464E-2
 6 77
37 M12828 Genes up-regulated in reverted NIH3T3 cells (fibroblasts transformed by activated KRAS [GeneID=3845] which then reverted to normal cells upon stable over-expression of a dominant negative form of CDC25 [GeneID=5923]) vs normal fibroblasts. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.552E-5 2.539E-3 2.357E-2
9.393E-2
 7 120
38 M6222 Genes up-regulated in Jurkat cells (transformed T lymphocytes) after knockdown of BCL11B [GeneID=64919] by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.652E-5 2.631E-3 2.443E-2
9.997E-2
 6 81
39 GSE37605 FOXP3 FUSION GFP VS IRES GFP TREG C57BL6 DN Genes down-regulated in T reg (FOXP3+ [GeneID=50943]) cells from B6 mice: Foxp3-Fusion-GFP versus Foxp3-ires-GFP. MSigDB C7: Immunologic Signatures (v5.1) 1.904E-5 2.954E-3 2.743E-2
1.152E-1
 8 171
40 M2256 Genes commonly down-regulated in UET-13 cells (mesenchymal progenitor) by expression of EWSR1 [GeneID=2130] fusions with ETS transcription factors FLI1 and ERG [GeneID=2313 ,2078]. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.134E-5 3.228E-3 2.997E-2
1.291E-1
 9 227
41 M1448 Genes up-regulated in RAW 264.7 cells (macrophage) 3 hr after stimulation with bacterial lipopolysaccharide (LPS). MSigDB C2: CGP Curated Gene Sets (v5.1) 2.656E-5 3.826E-3 3.553E-2
1.607E-1
 6 88
42 M12924 Genes down-regulated in primary granulosa cells in response to forskolin [PubChem=47936]. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.656E-5 3.826E-3 3.553E-2
1.607E-1
 6 88
43 M13251 Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 14 h time point that were not down-regulated at the previous time point, 12 h. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.015E-5 4.243E-3 3.939E-2
1.824E-1
 10 297
44 GSE13173 UNTREATED VS IL12 TREATED ACT CD8 TCELL DN Genes down-regulated in splenocytes from OT-1 TCR transgenic mice: control versus IL-12 treatment. MSigDB C7: Immunologic Signatures (v5.1) 3.171E-5 4.361E-3 4.049E-2
1.919E-1
 7 134
45 M4717 Genes consistently up-regulated in ACRP cells (ovarian cancer, resistant to cisplatin [PubChem=2767]) compared to the parental sensitive A2780 cells, regardless of cisplatin exposure. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.355E-5 4.512E-3 4.189E-2
2.030E-1
 4 28
46 M5301 Genes up-regulated in PC3 cells (prostate cancer) after EZH2 [GeneID=2146] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.641E-5 4.789E-3 4.447E-2
2.203E-1
 9 243
47 M10236 Genes up-regulated in biphasic (mixed) vs epithelial subtypes of malignant peritoneal mesothelioma. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.776E-5 4.861E-3 4.513E-2
2.285E-1
 10 305
48 M12591 Genes up-regulated by 3 h of euglycemic hyperinsulinemic clamp in the vastus lateralis muscle of healthy lean subjects. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.013E-5 4.888E-3 4.539E-2
2.428E-1
 12 442
49 M15069 Genes up-regulated in A549 cells (lung carcinoma) upon infection with RSV (respiratory syncytial virus) and up-regulated by further treatment with ribavirin [PubChem=5064]. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.445E-5 4.888E-3 4.539E-2
2.690E-1
 4 30
50 M2634 Genes up-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] and engineered to express ligand-activatable EGFR [Gene ID=1956]. MSigDB C6: Oncogenic Signatures (v5.1) 4.524E-5 4.888E-3 4.539E-2
2.737E-1
 8 193
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 2363 annotations before applied cutoff / 20974 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 54Dn SubClass 54Dn 1SK Top 500 All 54Dn SubClass 54Dn 1SK Top 500 All Brain Map - Allen iN 2.158E-8 3.115E-5 2.600E-4 5.100E-5 17 461
2 gudmap kidney adult RenalCapsule 500 kidney adult RenalCapsule top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 2.637E-8 3.115E-5 2.600E-4 6.230E-5 16 410
3 GSM777043 500 Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3 Immgen.org, GSE15907 8.155E-8 6.423E-5 5.360E-4 1.927E-4 16 445
4 Lungmap Mouse e16.5 Myofibro Top 500 All Lungmap Mouse e16.5 Myofibro Top 500 All Lungmap Mouse Single Cell (Lungmap.net) 2.315E-7 1.366E-4 1.140E-3 5.470E-4 15 420
5 DevelopingLowerUrinaryTract e14.5 urethra emap-30902 k3 1000 DevelopingLowerUrinaryTract e14.5 urethra emap-30902 k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 2.891E-7 1.366E-4 1.140E-3 6.831E-4 14 369
6 GSM777067 500 Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2 Immgen.org, GSE15907 6.041E-7 2.346E-4 1.958E-3 1.428E-3 15 453
7 gudmap developingLowerUrinaryTract e14.5 bladder 1000 k5 DevelopingLowerUrinaryTract e14.5 bladder emap-30872 k-means-cluster#5 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 6.950E-7 2.346E-4 1.958E-3 1.642E-3 14 397
8 endothelial SubClass MFSD2-hi Top 500 All endothelial SubClass MFSD2-hi Top 500 All Brain Map - Barres 1.961E-6 4.936E-4 4.119E-3 4.634E-3 15 498
9 gudmap developingLowerUrinaryTract e14.5 Genital tubercle 1000 k1 DevelopingLowerUrinaryTract e14.5 Genital tubercle emap-6706 k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.994E-6 4.936E-4 4.119E-3 4.712E-3 10 209
10 gudmap developingKidney e15.5 Medullary collecting duct 1000 k4 DevelopingKidney e15.5 Medullary collecting duct emap-28063 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 2.089E-6 4.936E-4 4.119E-3 4.936E-3 11 261
11 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k2 1000 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 3.284E-6 6.760E-4 5.641E-3 7.761E-3 12 330
12 GSM777055 500 Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4 Immgen.org, GSE15907 3.434E-6 6.760E-4 5.641E-3 8.115E-3 14 455
13 gudmap developingKidney e15.5 stage III -IV renal corpusc 1000 k5 DevelopingKidney e15.5 stage III -IV renal corpusc emap-27945 k-means-cluster#5 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.012E-6 6.760E-4 5.641E-3 9.480E-3 10 226
14 JC fibro 1000 K1 JC fibro top-relative-expression-ranked 1000 k-means-cluster#1 PCBC 4.302E-6 6.760E-4 5.641E-3 1.016E-2 14 464
15 54Dn SubClass 54Dn 1SK Top 500 Cluster 0 54Dn SubClass 54Dn 1SK Top 500 Cluster 0 Brain Map - Allen iN 4.399E-6 6.760E-4 5.641E-3 1.039E-2 6 62
16 PCBC ratio DE blastocyst vs DE cord blood cfr-2X-p05 DE blastocyst vs DE cord blood-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 4.655E-6 6.760E-4 5.641E-3 1.100E-2 7 96
17 gudmap developingKidney e15.5 Pelvic Mesenchyme 100 k2 DevelopingKidney e15.5 Pelvic Mesenchyme emap-8241 k-means-cluster#2 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 4.863E-6 6.760E-4 5.641E-3 1.149E-2 4 17
18 80Dn SubClass 80Dn 5 Top 500 All 80Dn SubClass 80Dn 5 Top 500 All Brain Map - Allen iN 5.490E-6 6.827E-4 5.697E-3 1.297E-2 14 474
19 80Dn SubClass 80Dn 5 Top 500 Cluster 0 80Dn SubClass 80Dn 5 Top 500 Cluster 0 Brain Map - Allen iN 5.490E-6 6.827E-4 5.697E-3 1.297E-2 14 474
20 54Dn Top 500 All 54Dn Top 500 All Brain Map - Allen iN 8.574E-6 8.679E-4 7.242E-3 2.026E-2 14 493
21 PCBC ratio EB blastocyst vs EB amniotic fluid MSC cfr-2X-p05 EB blastocyst vs EB amniotic fluid MSC-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 8.683E-6 8.679E-4 7.242E-3 2.052E-2 11 303
22 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 500 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 8.735E-6 8.679E-4 7.242E-3 2.064E-2 13 427
23 OPC Top 500 All OPC Top 500 All Brain Map - Barres 8.773E-6 8.679E-4 7.242E-3 2.073E-2 14 494
24 gudmap dev gonad e13.5 M gudmap devVasTestis Flk k4 1000 dev gonad e13.5 M DevVasTestis Flk k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 8.961E-6 8.679E-4 7.242E-3 2.118E-2 8 148
25 gudmap kidney adult Mesangium Meis 500 kidney adult Mesangium Meis top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 9.182E-6 8.679E-4 7.242E-3 2.170E-2 13 429
26 gudmap kidney e15.5 Podocyte MafB k3 200 kidney e15.5 Podocyte MafB k-means-cluster#3 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 9.741E-6 8.853E-4 7.388E-3 2.302E-2 4 20
27 GSM777046 500 Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4 Immgen.org, GSE15907 1.145E-5 1.002E-3 8.362E-3 2.706E-2 13 438
28 gudmap developingKidney e15.5 cortic collect duct 1000 k4 DevelopingKidney e15.5 cortic collect duct emap-28132 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.198E-5 1.011E-3 8.436E-3 2.831E-2 12 375
29 gudmap developingLowerUrinaryTract P1 bladder B 1000 k2 DevelopingLowerUrinaryTract P1 bladder B emap-30374 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.331E-5 1.085E-3 9.053E-3 3.146E-2 12 379
30 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k5 500 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k-means-cluster#5 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.978E-5 1.558E-3 1.300E-2 4.673E-2 8 165
31 gudmap kidney adult Mesangium Meis 200 kidney adult Mesangium Meis top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 2.157E-5 1.644E-3 1.372E-2
5.097E-2
 8 167
32 GSM777050 500 Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5 Immgen.org, GSE15907 2.247E-5 1.659E-3 1.384E-2
5.309E-2
 13 467
33 Lungmap Mouse e16.5 Myofibro Top 500 Cluster 1 Mouse Lung E16.5 Myofibroblast top 500 c1 Lungmap Mouse Single Cell (Lungmap.net) 2.949E-5 2.111E-3 1.762E-2
6.967E-2
 5 52
34 gudmap developingLowerUrinaryTract e14.5 bladder 500 k1 DevelopingLowerUrinaryTract e14.5 bladder emap-30872 k-means-cluster#1 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.380E-5 2.349E-3 1.960E-2
7.987E-2
 9 231
35 gudmap developingLowerUrinaryTract e14.5 bladder 500 DevelopingLowerUrinaryTract e14.5 bladder emap-30872 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.737E-5 2.442E-3 2.038E-2
8.829E-2
 12 421
36 gudmap kidney e15.5 Podocyte MafB k2 1000 kidney e15.5 Podocyte MafB k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 3.802E-5 2.442E-3 2.038E-2
8.983E-2
 6 90
37 DevelopingLowerUrinaryTract e14.5 bladder emap-6668 500 DevelopingLowerUrinaryTract e14.5 bladder emap-6668 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.823E-5 2.442E-3 2.038E-2
9.035E-2
 12 422
38 80Dn Top 500 All 80Dn Top 500 All Brain Map - Allen iN 4.017E-5 2.498E-3 2.084E-2
9.492E-2
 13 494
39 gudmap kidney adult GlomCapSys Tie2 k2 1000 kidney adult GlomCapSys Tie2 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.305E-5 2.608E-3 2.177E-2
1.017E-1
 6 92
40 GSM777063 100 Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 5.472E-5 3.232E-3 2.697E-2
1.293E-1
 6 96
41 Lungmap Mouse e16.5 Endothelial SubClass Mature Endothelial Top 500 Cluster 0 Mouse Lung E16.5 Endothelial Mature Endothelial c0 Lungmap Mouse Single Cell (Lungmap.net) 6.233E-5 3.510E-3 2.929E-2
1.473E-1
 7 143
42 gudmap developingKidney e13.5 podocyte cells 1000 k3 DevelopingKidney e13.5 podocyte cells emap-27773 k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 6.239E-5 3.510E-3 2.929E-2
1.474E-1
 9 250
43 gudmap kidney e15.5 Podocyte MafB k2 100 kidney e15.5 Podocyte MafB k-means-cluster#2 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 6.802E-5 3.738E-3 3.119E-2
1.607E-1
 3 12
44 GSM777037 500 Stromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 8.542E-5 4.588E-3 3.828E-2
2.019E-1
 12 459
45 gudmap developingKidney e15.5 S-shaped body 1000 k5 DevelopingKidney e15.5 S-shaped body emap-27855 k-means-cluster#5 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 9.156E-5 4.796E-3 4.003E-2
2.164E-1
 7 152
46 gudmap developingKidney e15.5 Ureteral Smooth Musc 500 DevelopingKidney e15.5 Ureteral Smooth Musc emap-28812 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 9.337E-5 4.796E-3 4.003E-2
2.206E-1
 11 393
47 GSM605834 500 Myeloid Cells, DC.8-4-11b-.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-2 Immgen.org, GSE15907 1.165E-4 5.857E-3 4.888E-2
2.753E-1
 11 403
48 gudmap developingKidney e15.5 ureter tip flank cortic collct 1000 k5 DevelopingKidney e15.5 ureter tip flank cortic collct emap-27752 k-means-cluster#5 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.278E-4 6.293E-3
5.252E-2
3.021E-1
 10 339
49 gudmap kidney e15.5 Podocyte MafB 500 kidney e15.5 Podocyte MafB top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.443E-4 6.961E-3
5.809E-2
3.411E-1
 11 413
50 GSM854299 500 Plasmacytoid, DC.pDC.8+.SLN, B220-FITC CD45-APC CD11c-eFluor780 GR1-PE CD8-eFlu, Lymph Node, avg-3 Immgen.org, GSE15907 1.505E-4 7.115E-3
5.937E-2
3.557E-1
 11 415
Show 45 more annotations

15: Computational [Display Chart] 353 annotations before applied cutoff / 9399 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 module 47 Genes in module 47 MSigDb: C4 - CM: Cancer Modules 1.287E-5 4.543E-3 2.928E-2 4.543E-3 11 216

16: MicroRNA [Display Chart] 1265 annotations before applied cutoff / 19844 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-421:PITA hsa-miR-421:PITA TOP PITA 6.789E-9 5.461E-6 4.216E-5 8.587E-6 16 355
2 miR-199a-star:PicTar miR-199a-star:PicTar PicTar 1.183E-8 5.461E-6 4.216E-5 1.496E-5 17 422
3 hsa-miR-548b-3p:PITA hsa-miR-548b-3p:PITA TOP PITA 1.338E-8 5.461E-6 4.216E-5 1.692E-5 13 230
4 miR-144:PicTar miR-144:PicTar PicTar 1.727E-8 5.461E-6 4.216E-5 2.184E-5 17 433
5 miR-186:PicTar miR-186:PicTar PicTar 2.492E-8 6.306E-6 4.868E-5 3.153E-5 17 444
6 miR-101:PicTar miR-101:PicTar PicTar 5.706E-7 1.203E-4 9.288E-4 7.218E-4 15 430
7 hsa-miR-448:PITA hsa-miR-448:PITA TOP PITA 3.835E-6 5.679E-4 4.384E-3 4.852E-3 14 438
8 hsa-miR-512-3p:PITA hsa-miR-512-3p:PITA TOP PITA 3.962E-6 5.679E-4 4.384E-3 5.012E-3 11 266
9 hsa-miR-34b:PITA hsa-miR-34b:PITA TOP PITA 4.040E-6 5.679E-4 4.384E-3 5.111E-3 13 379
10 hsa-miR-365*:mirSVR highEffct hsa-miR-365*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 5.931E-6 7.427E-4 5.734E-3 7.503E-3 14 455
11 hsa-miR-889:PITA hsa-miR-889:PITA TOP PITA 6.458E-6 7.427E-4 5.734E-3 8.170E-3 11 280
12 hsa-miR-491-3p:PITA hsa-miR-491-3p:PITA TOP PITA 8.156E-6 7.731E-4 5.968E-3 1.032E-2 11 287
13 hsa-miR-129-3p:PITA hsa-miR-129-3p:PITA TOP PITA 9.614E-6 7.731E-4 5.968E-3 1.216E-2 10 238
14 hsa-miR-320c:PITA hsa-miR-320c:PITA TOP PITA 1.112E-5 7.731E-4 5.968E-3 1.407E-2 14 481
15 hsa-miR-320a:PITA hsa-miR-320a:PITA TOP PITA 1.112E-5 7.731E-4 5.968E-3 1.407E-2 14 481
16 hsa-miR-320b:PITA hsa-miR-320b:PITA TOP PITA 1.112E-5 7.731E-4 5.968E-3 1.407E-2 14 481
17 hsa-miR-320d:PITA hsa-miR-320d:PITA TOP PITA 1.112E-5 7.731E-4 5.968E-3 1.407E-2 14 481
18 hsa-miR-199a-3p:PITA hsa-miR-199a-3p:PITA TOP PITA 1.161E-5 7.731E-4 5.968E-3 1.469E-2 11 298
19 hsa-miR-199b-3p:PITA hsa-miR-199b-3p:PITA TOP PITA 1.161E-5 7.731E-4 5.968E-3 1.469E-2 11 298
20 hsa-miR-105:PITA hsa-miR-105:PITA TOP PITA 1.679E-5 1.014E-3 7.831E-3 2.124E-2 13 433
21 AAGCACA,MIR-218:MSigDB AAGCACA,MIR-218:MSigDB MSigDB 1.684E-5 1.014E-3 7.831E-3 2.130E-2 12 370
22 ATATGCA,MIR-448:MSigDB ATATGCA,MIR-448:MSigDB MSigDB 1.777E-5 1.022E-3 7.886E-3 2.247E-2 9 203
23 miR-218:PicTar miR-218:PicTar PicTar 1.940E-5 1.067E-3 8.236E-3 2.454E-2 13 439
24 hsa-miR-649:PITA hsa-miR-649:PITA TOP PITA 2.598E-5 1.361E-3 1.051E-2 3.287E-2 9 213
25 hsa-miR-1305:PITA hsa-miR-1305:PITA TOP PITA 2.690E-5 1.361E-3 1.051E-2 3.403E-2 13 453
26 hsa-miR-549:PITA hsa-miR-549:PITA TOP PITA 3.033E-5 1.421E-3 1.097E-2 3.837E-2 8 167
27 hsa-miR-642:PITA hsa-miR-642:PITA TOP PITA 3.033E-5 1.421E-3 1.097E-2 3.837E-2 8 167
28 AATGTGA,MIR-23A:MSigDB AATGTGA,MIR-23A:MSigDB MSigDB 3.279E-5 1.430E-3 1.104E-2 4.148E-2 12 396
29 AATGTGA,MIR-23B:MSigDB AATGTGA,MIR-23B:MSigDB MSigDB 3.279E-5 1.430E-3 1.104E-2 4.148E-2 12 396
30 hsa-miR-145:PITA hsa-miR-145:PITA TOP PITA 3.704E-5 1.562E-3 1.206E-2 4.686E-2 12 401
31 hsa-miR-501-5p:PITA hsa-miR-501-5p:PITA TOP PITA 3.913E-5 1.597E-3 1.233E-2 4.950E-2 11 340
32 hsa-miR-182:PITA hsa-miR-182:PITA TOP PITA 4.779E-5 1.889E-3 1.458E-2
6.045E-2
 13 479
33 hsa-miR-1279:PITA hsa-miR-1279:PITA TOP PITA 6.166E-5 2.364E-3 1.825E-2
7.800E-2
 9 238
34 hsa-miR-433:PITA hsa-miR-433:PITA TOP PITA 7.703E-5 2.716E-3 2.097E-2
9.744E-2
 9 245
35 hsa-miR-507:PITA hsa-miR-507:PITA TOP PITA 7.730E-5 2.716E-3 2.097E-2
9.778E-2
 10 304
36 hsa-miR-557:PITA hsa-miR-557:PITA TOP PITA 7.730E-5 2.716E-3 2.097E-2
9.778E-2
 10 304
37 miR-323:PicTar miR-323:PicTar PicTar 8.454E-5 2.777E-3 2.144E-2
1.069E-1
 9 248
38 hsa-miR-1252:PITA hsa-miR-1252:PITA TOP PITA 8.561E-5 2.777E-3 2.144E-2
1.083E-1
 11 371
39 miR-302c-star:PicTar miR-302c-star:PicTar PicTar 8.561E-5 2.777E-3 2.144E-2
1.083E-1
 11 371
40 hsa-let-7a:miRTarbase hsa-let-7a:miRTarbase miRTarbase 9.240E-5 2.899E-3 2.238E-2
1.169E-1
 4 33
41 hsa-miR-3130-3p:mirSVR highEffct hsa-miR-3130-3p:mirSVR nonconserved highEffect-0.5 MicroRNA.org 9.396E-5 2.899E-3 2.238E-2
1.189E-1
 12 442
42 hsa-miR-501-3p:mirSVR highEffct hsa-miR-501-3p:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.112E-4 3.275E-3 2.528E-2
1.407E-1
 12 450
43 hsa-miR-1185:PITA hsa-miR-1185:PITA TOP PITA 1.113E-4 3.275E-3 2.528E-2
1.408E-1
 6 104
44 hsa-miR-323-3p:PITA hsa-miR-323-3p:PITA TOP PITA 1.160E-4 3.336E-3 2.575E-2
1.468E-1
 11 384
45 hsa-miR-222:PITA hsa-miR-222:PITA TOP PITA 1.608E-4 4.474E-3 3.454E-2
2.034E-1
 9 270
46 hsa-miR-221:PITA hsa-miR-221:PITA TOP PITA 1.746E-4 4.474E-3 3.454E-2
2.209E-1
 9 273
47 miR-141:PicTar miR-141:PicTar PicTar 1.753E-4 4.474E-3 3.454E-2
2.218E-1
 10 336
48 hsa-miR-26a:PITA hsa-miR-26a:PITA TOP PITA 1.768E-4 4.474E-3 3.454E-2
2.237E-1
 12 473
49 hsa-miR-26b:PITA hsa-miR-26b:PITA TOP PITA 1.768E-4 4.474E-3 3.454E-2
2.237E-1
 12 473
50 hsa-miR-1297:PITA hsa-miR-1297:PITA TOP PITA 1.768E-4 4.474E-3 3.454E-2
2.237E-1
 12 473
Show 45 more annotations

17: Drug [Display Chart] 18283 annotations before applied cutoff / 22098 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 2801 DN Emetine dihydrochloride [316-42-7]; Down 200; 7.2uM; MCF7; HT HG-U133A Broad Institute CMAP 1.431E-9 2.342E-5 2.433E-4 2.617E-5 12 172
2 3290 DN Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; MCF7; HT HG-U133A Broad Institute CMAP 2.562E-9 2.342E-5 2.433E-4 4.684E-5 12 181
3 1926 DN Glipizide [29094-61-9]; Down 200; 9uM; PC3; HG-U133A Broad Institute CMAP 5.302E-9 3.231E-5 3.358E-4 9.694E-5 12 193
4 3998 DN Etifenin [63245-28-3]; Down 200; 12.4uM; PC3; HT HG-U133A Broad Institute CMAP 2.513E-8 1.149E-4 1.194E-3 4.595E-4 11 178
5 1597 UP Enoxacin [74011-58-8]; Up 200; 12.4uM; HL60; HG-U133A Broad Institute CMAP 7.120E-8 2.285E-4 2.374E-3 1.302E-3 11 197
6 1938 UP Cyproheptadine hydrochloride [969-33-5]; Up 200; 12.4uM; PC3; HG-U133A Broad Institute CMAP 7.497E-8 2.285E-4 2.374E-3 1.371E-3 11 198
7 1925 DN Bromocryptine mesylate [22260-51-1]; Down 200; 5.4uM; PC3; HG-U133A Broad Institute CMAP 5.975E-7 1.500E-3 1.559E-2 1.093E-2 10 194
8 1586 UP Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; HL60; HG-U133A Broad Institute CMAP 6.564E-7 1.500E-3 1.559E-2 1.200E-2 10 196
9 7477 UP Atracurium besylate [64228-81-5]; Up 200; 3.2uM; MCF7; HT HG-U133A Broad Institute CMAP 7.542E-7 1.532E-3 1.592E-2 1.379E-2 10 199
10 4545 DN Ethotoin [86-35-1]; Down 200; 19.6uM; PC3; HT HG-U133A Broad Institute CMAP 4.085E-6 6.323E-3
6.571E-2
7.468E-2
 9 188
11 4647 DN Butylparaben [94-26-8]; Down 200; 20.6uM; PC3; HT HG-U133A Broad Institute CMAP 4.647E-6 6.323E-3
6.571E-2
8.497E-2
 9 191
12 5058 DN Homatropine hydrobromide (R,S) [51-56-9]; Down 200; 11.2uM; PC3; HT HG-U133A Broad Institute CMAP 4.849E-6 6.323E-3
6.571E-2
8.866E-2
 9 192
13 1929 DN Cotinine (-) [486-56-6]; Down 200; 22.6uM; PC3; HG-U133A Broad Institute CMAP 4.849E-6 6.323E-3
6.571E-2
8.866E-2
 9 192
14 7097 UP GSK-3beta Inhibitor VIII; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 5.059E-6 6.323E-3
6.571E-2
9.249E-2
 9 193
15 D003513 Cycloheximide CTD 5.966E-6 6.323E-3
6.571E-2
1.091E-1
 13 437
16 2810 UP Vitexin [3681-93-4]; Up 200; 9.2uM; MCF7; HT HG-U133A Broad Institute CMAP 5.975E-6 6.323E-3
6.571E-2
1.092E-1
 9 197
17 460 DN deferoxamine mesylate salt; Down 200; 100uM; PC3; HG-U133A Broad Institute CMAP 5.975E-6 6.323E-3
6.571E-2
1.092E-1
 9 197
18 5314 DN Amikacin hydrate [37517-28-5]; Down 200; 6.6uM; MCF7; HT HG-U133A Broad Institute CMAP 6.225E-6 6.323E-3
6.571E-2
1.138E-1
 9 198
19 CID000006331 borane Stitch 1.109E-5 1.056E-2
1.097E-1
2.028E-1
 10 269
20 CID000018300 BP-1,6-quinone Stitch 1.155E-5 1.056E-2
1.097E-1
2.111E-1
 4 22
21 C025462 sulindac sulfide CTD 1.860E-5 1.620E-2
1.683E-1
3.401E-1
 9 227
22 4827 DN Emetine dihydrochloride [316-42-7]; Down 200; 7.2uM; MCF7; HT HG-U133A Broad Institute CMAP 2.156E-5 1.709E-2
1.776E-1
3.941E-1
 8 177
23 CID000023981 europium Stitch 2.257E-5 1.709E-2
1.776E-1
4.126E-1
 6 87
24 3895 UP Diethylstilbestrol [56-53-1]; Up 200; 15uM; MCF7; HT HG-U133A Broad Institute CMAP 2.337E-5 1.709E-2
1.776E-1
4.273E-1
 8 179
25 4585 DN Captopril [62571-86-2]; Down 200; 17.2uM; PC3; HT HG-U133A Broad Institute CMAP 2.337E-5 1.709E-2
1.776E-1
4.273E-1
 8 179
26 CID000005291 imatinib Stitch 2.592E-5 1.822E-2
1.894E-1
4.738E-1
 12 430
27 5364 DN Anisomycin [22862-76-6]; Down 200; 15uM; MCF7; HT HG-U133A Broad Institute CMAP 2.960E-5 1.933E-2
2.009E-1
5.411E-1
 8 185
28 6735 DN Neostigmine bromide [114-80-7]; Down 200; 13.2uM; PC3; HT HG-U133A Broad Institute CMAP 3.320E-5 1.933E-2
2.009E-1
6.070E-1
 8 188
29 3232 UP Mitoxantrone dihydrochloride [70476-82-3]; Up 200; 7.8uM; MCF7; HT HG-U133A Broad Institute CMAP 3.580E-5 1.933E-2
2.009E-1
6.545E-1
 8 190
30 1153 UP Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; HL60; HT HG-U133A Broad Institute CMAP 3.856E-5 1.933E-2
2.009E-1
7.051E-1
 8 192
31 1958 DN Chlortetracycline hydrochloride [64-72-2]; Down 200; 7.8uM; PC3; HG-U133A Broad Institute CMAP 4.001E-5 1.933E-2
2.009E-1
7.316E-1
 8 193
32 1396 DN Dexamethasone acetate [1177-87-3]; Down 200; 9.2uM; HL60; HG-U133A Broad Institute CMAP 4.151E-5 1.933E-2
2.009E-1
7.589E-1
 8 194
33 7164 UP Albendazole [54965-21-8]; Up 200; 15uM; MCF7; HT HG-U133A Broad Institute CMAP 4.151E-5 1.933E-2
2.009E-1
7.589E-1
 8 194
34 6163 DN haloperidol; Down 200; 10uM; HL60; HT HG-U133A Broad Institute CMAP 4.305E-5 1.933E-2
2.009E-1
7.870E-1
 8 195
35 4272 DN Flumethasone [2135-17-3]; Down 200; 9.8uM; PC3; HT HG-U133A Broad Institute CMAP 4.305E-5 1.933E-2
2.009E-1
7.870E-1
 8 195
36 1978 UP Prednisone [53-03-2]; Up 200; 11.2uM; HL60; HG-U133A Broad Institute CMAP 4.464E-5 1.933E-2
2.009E-1
8.161E-1
 8 196
37 1432 DN Chlorphensin carbamate [886-74-8]; Down 200; 16.2uM; HL60; HG-U133A Broad Institute CMAP 4.464E-5 1.933E-2
2.009E-1
8.161E-1
 8 196
38 2950 DN Roxarsone [121-19-7]; Down 200; 15.2uM; HL60; HT HG-U133A Broad Institute CMAP 4.464E-5 1.933E-2
2.009E-1
8.161E-1
 8 196
39 6310 UP Esculin Hydrate [531-75-9]; Up 200; 11.8uM; PC3; HT HG-U133A Broad Institute CMAP 4.627E-5 1.933E-2
2.009E-1
8.460E-1
 8 197
40 2819 UP beta- Belladonnine dichloroethylate [191355-47-2]; Up 200; 6uM; MCF7; HT HG-U133A Broad Institute CMAP 4.627E-5 1.933E-2
2.009E-1
8.460E-1
 8 197
41 1902 UP Dicyclomine hydrochloride [67-92-5]; Up 200; 11.6uM; PC3; HG-U133A Broad Institute CMAP 4.796E-5 1.933E-2
2.009E-1
8.768E-1
 8 198
42 2803 UP Yohimbinic acid monohydrate [27801-27-2]; Up 200; 11.2uM; MCF7; HT HG-U133A Broad Institute CMAP 4.796E-5 1.933E-2
2.009E-1
8.768E-1
 8 198
43 7514 DN 11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; MCF7; HT HG-U133A Broad Institute CMAP 4.796E-5 1.933E-2
2.009E-1
8.768E-1
 8 198
44 D014302 Trinitrobenzenesulfonic Acid CTD 4.932E-5 1.933E-2
2.009E-1
9.017E-1
 11 388
45 5309 DN Diltiazem hydrochloride [33286-22-5]; Down 200; 8.8uM; MCF7; HT HG-U133A Broad Institute CMAP 4.970E-5 1.933E-2
2.009E-1
9.086E-1
 8 199
46 5517 DN Rimexolone [49697-38-3]; Down 200; 10.8uM; MCF7; HT HG-U133A Broad Institute CMAP 4.970E-5 1.933E-2
2.009E-1
9.086E-1
 8 199
47 122 DN alpha-estradiol; Down 200; 0.01uM; MCF7; HG-U133A Broad Institute CMAP 4.970E-5 1.933E-2
2.009E-1
9.086E-1
 8 199
48 4807 DN Nystatine [1400-61-9]; Down 200; 4.4uM; MCF7; HT HG-U133A Broad Institute CMAP 5.148E-5 1.961E-2
2.038E-1
9.413E-1
 8 200
49 C070081 fulvestrant CTD 6.502E-5 2.426E-2
2.521E-1
1.000E0
 12 473
50 CID000100299 8-Cl-cAMP Stitch 7.649E-5 2.797E-2
2.906E-1
1.000E0
 5 67
Show 45 more annotations

18: Disease [Display Chart] 1682 annotations before applied cutoff / 16150 genes in category

No results to display