Toppgene analysis for aggregated_1964_log, IC15, positive side

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1: GO: Molecular Function [Display Chart] 582 annotations before applied cutoff / 18819 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0019838 growth factor binding 1.198E-5 4.459E-3 3.097E-2 6.971E-3 9 142
2 GO:0008093 cytoskeletal adaptor activity 1.532E-5 4.459E-3 3.097E-2 8.918E-3 4 16
3 GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity 1.083E-4 2.102E-2
1.459E-1
6.305E-2
 3 10
4 GO:0019199 transmembrane receptor protein kinase activity 2.858E-4 4.158E-2
2.888E-1
1.663E-1
 6 91

2: GO: Biological Process [Display Chart] 3664 annotations before applied cutoff / 18785 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0001525 angiogenesis 9.825E-7 3.600E-3 3.162E-2 3.600E-3 18 465
2 GO:0070371 ERK1 and ERK2 cascade 5.859E-6 8.340E-3
7.326E-2
 2.147E-2 13 285
3 GO:0048568 embryonic organ development 7.077E-6 8.340E-3
7.326E-2
 2.593E-2 17 483
4 GO:0032970 regulation of actin filament-based process 9.105E-6 8.340E-3
7.326E-2
 3.336E-2 14 343
5 GO:2000027 regulation of organ morphogenesis 1.747E-5 9.601E-3
8.434E-2
6.403E-2
 12 270
6 GO:0070372 regulation of ERK1 and ERK2 cascade 1.747E-5 9.601E-3
8.434E-2
6.403E-2
 12 270
7 GO:0042692 muscle cell differentiation 1.834E-5 9.601E-3
8.434E-2
6.721E-2
 15 415
8 GO:0043583 ear development 2.972E-5 1.337E-2
1.174E-1
1.089E-1
 11 240
9 GO:0060449 bud elongation involved in lung branching 3.299E-5 1.337E-2
1.174E-1
1.209E-1
 3 7
10 GO:0051146 striated muscle cell differentiation 3.648E-5 1.337E-2
1.174E-1
1.337E-1
 12 291
11 GO:0090287 regulation of cellular response to growth factor stimulus 5.347E-5 1.532E-2
1.346E-1
1.959E-1
 11 256
12 GO:0032956 regulation of actin cytoskeleton organization 5.393E-5 1.532E-2
1.346E-1
1.976E-1
 12 303
13 GO:0048738 cardiac muscle tissue development 6.315E-5 1.532E-2
1.346E-1
2.314E-1
 10 216
14 GO:0010876 lipid localization 6.589E-5 1.532E-2
1.346E-1
2.414E-1
 13 359
15 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 6.941E-5 1.532E-2
1.346E-1
2.543E-1
 6 70
16 GO:0050769 positive regulation of neurogenesis 7.073E-5 1.532E-2
1.346E-1
2.592E-1
 15 467
17 GO:0007596 blood coagulation 7.577E-5 1.532E-2
1.346E-1
2.776E-1
 13 364
18 GO:0050777 negative regulation of immune response 8.512E-5 1.532E-2
1.346E-1
3.119E-1
 8 141
19 GO:0007599 hemostasis 8.691E-5 1.532E-2
1.346E-1
3.184E-1
 13 369
20 GO:0050817 coagulation 8.691E-5 1.532E-2
1.346E-1
3.184E-1
 13 369
21 GO:0040017 positive regulation of locomotion 9.167E-5 1.532E-2
1.346E-1
3.359E-1
 15 478
22 GO:0032368 regulation of lipid transport 9.199E-5 1.532E-2
1.346E-1
3.371E-1
 7 106
23 GO:0045666 positive regulation of neuron differentiation 1.077E-4 1.580E-2
1.388E-1
3.946E-1
 13 377
24 GO:0055017 cardiac muscle tissue growth 1.102E-4 1.580E-2
1.388E-1
4.036E-1
 6 76
25 GO:0048562 embryonic organ morphogenesis 1.113E-4 1.580E-2
1.388E-1
4.078E-1
 12 327
26 GO:0060038 cardiac muscle cell proliferation 1.121E-4 1.580E-2
1.388E-1
4.109E-1
 5 48
27 GO:0070374 positive regulation of ERK1 and ERK2 cascade 1.239E-4 1.681E-2
1.476E-1
4.539E-1
 9 190
28 GO:0048701 embryonic cranial skeleton morphogenesis 1.502E-4 1.908E-2
1.676E-1
5.502E-1
 5 51
29 GO:0070493 thrombin-activated receptor signaling pathway 1.510E-4 1.908E-2
1.676E-1
5.534E-1
 3 11
30 GO:0030335 positive regulation of cell migration 1.572E-4 1.920E-2
1.687E-1
5.760E-1
 14 446
31 GO:0050920 regulation of chemotaxis 1.756E-4 2.075E-2
1.823E-1
6.434E-1
 9 199
32 GO:0048762 mesenchymal cell differentiation 1.823E-4 2.081E-2
1.828E-1
6.680E-1
 9 200
33 GO:0040013 negative regulation of locomotion 1.874E-4 2.081E-2
1.828E-1
6.868E-1
 11 295
34 GO:0001667 ameboidal-type cell migration 1.933E-4 2.084E-2
1.830E-1
7.084E-1
 12 347
35 GO:0060419 heart growth 2.047E-4 2.143E-2
1.882E-1
7.499E-1
 6 85
36 GO:2000147 positive regulation of cell motility 2.113E-4 2.151E-2
1.889E-1
7.743E-1
 14 459
37 GO:0048863 stem cell differentiation 2.361E-4 2.331E-2
2.048E-1
8.651E-1
 11 303
38 GO:0043542 endothelial cell migration 2.418E-4 2.331E-2
2.048E-1
8.859E-1
 8 164
39 GO:0048015 phosphatidylinositol-mediated signaling 2.530E-4 2.346E-2
2.060E-1
9.272E-1
 9 209
40 GO:0014065 phosphatidylinositol 3-kinase signaling 2.734E-4 2.346E-2
2.060E-1
1.000E0
 8 167
41 GO:0051272 positive regulation of cellular component movement 2.749E-4 2.346E-2
2.060E-1
1.000E0
 14 471
42 GO:0032370 positive regulation of lipid transport 2.769E-4 2.346E-2
2.060E-1
1.000E0
 5 58
43 GO:0048017 inositol lipid-mediated signaling 2.812E-4 2.346E-2
2.060E-1
1.000E0
 9 212
44 GO:0035239 tube morphogenesis 2.888E-4 2.346E-2
2.060E-1
1.000E0
 13 417
45 GO:0072001 renal system development 2.951E-4 2.346E-2
2.060E-1
1.000E0
 11 311
46 GO:0060537 muscle tissue development 3.023E-4 2.346E-2
2.060E-1
1.000E0
 13 419
47 GO:0001656 metanephros development 3.151E-4 2.346E-2
2.060E-1
1.000E0
 6 92
48 GO:1900046 regulation of hemostasis 3.151E-4 2.346E-2
2.060E-1
1.000E0
 6 92
49 GO:0030193 regulation of blood coagulation 3.151E-4 2.346E-2
2.060E-1
1.000E0
 6 92
50 GO:0042476 odontogenesis 3.265E-4 2.346E-2
2.060E-1
1.000E0
 7 130
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 290 annotations before applied cutoff / 19172 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0043034 costamere 5.588E-5 1.620E-2
1.013E-1
 1.620E-2 4 22
2 GO:0098794 postsynapse 1.533E-4 1.707E-2
1.067E-1
 4.446E-2 14 454
3 GO:0030018 Z disc 1.766E-4 1.707E-2
1.067E-1
5.121E-2
 7 120
4 GO:0031674 I band 3.802E-4 2.757E-2
1.723E-1
1.103E-1
 7 136
5 GO:0044420 extracellular matrix component 5.143E-4 2.983E-2
1.864E-1
1.492E-1
 7 143
6 GO:0030017 sarcomere 7.665E-4 3.705E-2
2.315E-1
2.223E-1
 8 199
7 GO:0060076 excitatory synapse 9.994E-4 3.861E-2
2.413E-1
2.898E-1
 9 258
8 GO:0045177 apical part of cell 1.065E-3 3.861E-2
2.413E-1
3.089E-1
 12 429
9 GO:0044449 contractile fiber part 1.299E-3 3.959E-2
2.474E-1
3.767E-1
 8 216
10 GO:0031012 extracellular matrix 1.426E-3 3.959E-2
2.474E-1
4.135E-1
 12 444
11 GO:0030016 myofibril 1.502E-3 3.959E-2
2.474E-1
4.355E-1
 8 221
12 GO:0045211 postsynaptic membrane 1.681E-3 4.001E-2
2.500E-1
4.876E-1
 8 225
13 GO:0016324 apical plasma membrane 1.793E-3 4.001E-2
2.500E-1
5.201E-1
 10 337
14 GO:0030426 growth cone 2.094E-3 4.133E-2
2.583E-1
6.072E-1
 7 182
15 GO:0043292 contractile fiber 2.206E-3 4.133E-2
2.583E-1
6.396E-1
 8 235
16 GO:0030427 site of polarized growth 2.438E-3 4.133E-2
2.583E-1
7.072E-1
 7 187
17 GO:0014731 spectrin-associated cytoskeleton 2.549E-3 4.133E-2
2.583E-1
7.393E-1
 2 8
18 GO:0097060 synaptic membrane 2.800E-3 4.133E-2
2.583E-1
8.120E-1
 9 300
19 GO:0005911 cell-cell junction 2.848E-3 4.133E-2
2.583E-1
8.259E-1
 11 420
20 GO:0016323 basolateral plasma membrane 2.851E-3 4.133E-2
2.583E-1
8.267E-1
 8 245
21 GO:0045178 basal part of cell 3.530E-3 4.875E-2
3.046E-1
1.000E0
 4 64
22 GO:0042383 sarcolemma 3.930E-3 4.973E-2
3.108E-1
1.000E0
 6 153
23 GO:0016529 sarcoplasmic reticulum 3.944E-3 4.973E-2
3.108E-1
1.000E0
 4 66
Show 18 more annotations

4: Human Phenotype [Display Chart] 622 annotations before applied cutoff / 4410 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 3132 annotations before applied cutoff / 9299 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0011185 absent primitive endoderm 1.322E-5 3.787E-2
3.267E-1
 4.139E-2 3 4
2 MP:0003935 abnormal craniofacial development 5.546E-5 3.787E-2
3.267E-1
1.737E-1
 17 381
3 MP:0013545 cleft hard palate 6.413E-5 3.787E-2
3.267E-1
2.008E-1
 8 91
4 MP:0009655 abnormal secondary palate development 6.841E-5 3.787E-2
3.267E-1
2.142E-1
 9 118
5 MP:0003755 abnormal palate morphology 7.832E-5 3.787E-2
3.267E-1
2.453E-1
 15 316
6 MP:0009653 abnormal palate development 8.320E-5 3.787E-2
3.267E-1
2.606E-1
 9 121
7 MP:0000111 cleft palate 1.028E-4 3.787E-2
3.267E-1
3.219E-1
 14 287
8 MP:0009887 abnormal palatal shelf fusion at midline 1.073E-4 3.787E-2
3.267E-1
3.362E-1
 7 73
9 MP:0003756 abnormal hard palate morphology 1.138E-4 3.787E-2
3.267E-1
3.565E-1
 9 126
10 MP:0003115 abnormal respiratory system development 1.209E-4 3.787E-2
3.267E-1
3.787E-1
 11 188
Show 5 more annotations

6: Domain [Display Chart] 1250 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR026823 cEGF InterPro 5.488E-6 3.430E-3 2.644E-2 6.859E-3 5 26
2 PF12662 cEGF Pfam 5.488E-6 3.430E-3 2.644E-2 6.859E-3 5 26
3 SM00218 ZU5 SMART 8.117E-5 2.357E-2
1.817E-1
1.015E-1
 3 9
4 PS51145 ZU5 PROSITE 1.151E-4 2.357E-2
1.817E-1
1.439E-1
 3 10
5 2.40.155.10 - Gene3D 1.571E-4 2.357E-2
1.817E-1
1.964E-1
 3 11
6 IPR023413 GFP-like InterPro 1.571E-4 2.357E-2
1.817E-1
1.964E-1
 3 11
7 IPR009030 Growth fac rcpt InterPro 1.881E-4 2.357E-2
1.817E-1
2.351E-1
 8 156
8 PF00791 ZU5 Pfam 2.079E-4 2.357E-2
1.817E-1
2.599E-1
 3 12
9 IPR000906 ZU5 dom InterPro 2.079E-4 2.357E-2
1.817E-1
2.599E-1
 3 12
10 PF07645 EGF CA Pfam 2.344E-4 2.357E-2
1.817E-1
2.930E-1
 6 86
11 SM00179 EGF CA SMART 2.400E-4 2.357E-2
1.817E-1
3.000E-1
 7 122
12 IPR001881 EGF-like Ca-bd dom InterPro 2.652E-4 2.357E-2
1.817E-1
3.315E-1
 7 124
13 IPR020635 Tyr kinase cat dom InterPro 2.658E-4 2.357E-2
1.817E-1
3.322E-1
 6 88
14 SM00219 TyrKc SMART 2.658E-4 2.357E-2
1.817E-1
3.322E-1
 6 88
15 SM00682 G2F SMART 3.017E-4 2.357E-2
1.817E-1
3.771E-1
 2 3
16 IPR026716 FAM122 InterPro 3.017E-4 2.357E-2
1.817E-1
3.771E-1
 2 3
17 PF07714 Pkinase Tyr Pfam 3.376E-4 2.482E-2
1.913E-1
4.219E-1
 7 129
18 PS00109 PROTEIN KINASE TYR PROSITE 4.497E-4 2.649E-2
2.042E-1
5.621E-1
 6 97
19 IPR008266 Tyr kinase AS InterPro 4.497E-4 2.649E-2
2.042E-1
5.621E-1
 6 97
20 IPR001245 Ser-Thr/Tyr kinase cat dom InterPro 5.072E-4 2.649E-2
2.042E-1
6.340E-1
 7 138
21 PS00010 ASX HYDROXYL PROSITE 5.291E-4 2.649E-2
2.042E-1
6.614E-1
 6 100
22 IPR006605 G2 nidogen/fibulin G2F InterPro 5.994E-4 2.649E-2
2.042E-1
7.492E-1
 2 4
23 PS50993 NIDOGEN G2 PROSITE 5.994E-4 2.649E-2
2.042E-1
7.492E-1
 2 4
24 IPR009017 GFP InterPro 5.994E-4 2.649E-2
2.042E-1
7.492E-1
 2 4
25 PF07474 G2F Pfam 5.994E-4 2.649E-2
2.042E-1
7.492E-1
 2 4
26 IPR003912 Protea act rcpt InterPro 5.994E-4 2.649E-2
2.042E-1
7.492E-1
 2 4
27 SM00408 IGc2 SMART 6.542E-4 2.649E-2
2.042E-1
8.177E-1
 9 235
28 IPR003598 Ig sub2 InterPro 6.542E-4 2.649E-2
2.042E-1
8.177E-1
 9 235
29 SM00181 EGF SMART 6.743E-4 2.649E-2
2.042E-1
8.429E-1
 9 236
30 PF00047 ig Pfam 7.047E-4 2.649E-2
2.042E-1
8.808E-1
 8 190
31 IPR013098 Ig I-set InterPro 7.047E-4 2.649E-2
2.042E-1
8.808E-1
 8 190
32 PF07679 I-set Pfam 7.047E-4 2.649E-2
2.042E-1
8.808E-1
 8 190
33 IPR013151 Immunoglobulin InterPro 7.047E-4 2.649E-2
2.042E-1
8.808E-1
 8 190
34 IPR000152 EGF-type Asp/Asn hydroxyl site InterPro 7.205E-4 2.649E-2
2.042E-1
9.006E-1
 6 106
35 IPR006530 YD InterPro 9.923E-4 3.519E-2
2.712E-1
1.000E0
 2 5
36 IPR000742 EGF-like dom InterPro 1.013E-3 3.519E-2
2.712E-1
1.000E0
 9 250
37 IPR003599 Ig sub InterPro 1.208E-3 3.975E-2
3.064E-1
1.000E0
 12 421
38 SM00409 IG SMART 1.208E-3 3.975E-2
3.064E-1
1.000E0
 12 421
39 IPR011044 Quino amine DH bsu InterPro 1.351E-3 4.330E-2
3.338E-1
1.000E0
 3 22
40 IPR013032 EGF-like CS InterPro 1.404E-3 4.387E-2
3.382E-1
1.000E0
 9 262
41 PS50835 IG LIKE PROSITE 1.508E-3 4.598E-2
3.545E-1
1.000E0
 13 492
42 PS01186 EGF 2 PROSITE 1.558E-3 4.637E-2
3.575E-1
1.000E0
 9 266
Show 37 more annotations

7: Pathway [Display Chart] 949 annotations before applied cutoff / 10916 genes in category

No results to display

8: Pubmed [Display Chart] 25766 annotations before applied cutoff / 51853 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 20628624 Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". Pubmed 5.965E-11 7.684E-7 8.249E-6 1.537E-6 11 172
2 20628624:gr Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". GeneRIF 5.965E-11 7.684E-7 8.249E-6 1.537E-6 11 172
3 20634891:gr Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. GeneRIF 4.521E-10 2.912E-6 3.126E-5 1.165E-5 13 331
4 20634891 Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Pubmed 4.521E-10 2.912E-6 3.126E-5 1.165E-5 13 331
5 25241761 Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. Pubmed 1.860E-8 9.583E-5 1.029E-3 4.791E-4 12 371
6 10893266 Ankyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration. Pubmed 5.077E-8 1.189E-4 1.276E-3 1.308E-3 3 3
7 18349119:gr Keratin overexpression levels correlate with the extent of spontaneous pancreatic injury. GeneRIF 5.077E-8 1.189E-4 1.276E-3 1.308E-3 3 3
8 23776077:gr PDGFR¿ and CD51 mark human nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion. GeneRIF 5.077E-8 1.189E-4 1.276E-3 1.308E-3 3 3
9 18941637:gr Contrasting expression of keratins in mouse and human embryonic stem cells. GeneRIF 5.077E-8 1.189E-4 1.276E-3 1.308E-3 3 3
10 19585610 Keratin variants are overrepresented in primary biliary cirrhosis and associate with disease severity. Pubmed 5.077E-8 1.189E-4 1.276E-3 1.308E-3 3 3
11 19585610:gr Keratin variants are overrepresented in primary biliary cirrhosis and associate with disease severity. GeneRIF 5.077E-8 1.189E-4 1.276E-3 1.308E-3 3 3
12 22261194 Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury. Pubmed 1.541E-7 3.069E-4 3.295E-3 3.970E-3 6 64
13 10809736 Dissection of protein linkage between keratins and pinin, a protein with dual location at desmosome-intermediate filament complex and in the nucleus. Pubmed 2.025E-7 3.069E-4 3.295E-3 5.218E-3 3 4
14 21705376 Quantitative expression study of four cytokeratins and p63 in squamous cell carcinoma of the tongue: suitability for sentinel node navigation surgery using one-step nucleic acid amplification. Pubmed 2.025E-7 3.069E-4 3.295E-3 5.218E-3 3 4
15 20398190 Significant high expression of cytokeratins 7, 8, 18, 19 in pulmonary large cell neuroendocrine carcinomas, compared to small cell lung carcinomas. Pubmed 2.025E-7 3.069E-4 3.295E-3 5.218E-3 3 4
16 21705376:gr Quantitative expression study of four cytokeratins and p63 in squamous cell carcinoma of the tongue: suitability for sentinel node navigation surgery using one-step nucleic acid amplification. GeneRIF 2.025E-7 3.069E-4 3.295E-3 5.218E-3 3 4
17 20398190:gr Significant high expression of cytokeratins 7, 8, 18, 19 in pulmonary large cell neuroendocrine carcinomas, compared to small cell lung carcinomas. GeneRIF 2.025E-7 3.069E-4 3.295E-3 5.218E-3 3 4
18 15314064 Raf-1 activation disrupts its binding to keratins during cell stress. Pubmed 5.049E-7 7.227E-4 7.758E-3 1.301E-2 3 5
19 25429064 Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. Pubmed 8.636E-7 1.140E-3 1.223E-2 2.225E-2 7 136
20 20881960 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Pubmed 8.845E-7 1.140E-3 1.223E-2 2.279E-2 8 198
21 18941637 Contrasting expression of keratins in mouse and human embryonic stem cells. Pubmed 1.007E-6 1.236E-3 1.326E-2 2.595E-2 3 6
22 20446891 A comprehensive study of the association between the EGFR and ERBB2 genes and glioma risk. Pubmed 1.757E-6 1.887E-3 2.025E-2 4.528E-2 3 7
23 23776077 PDGFR¿ and CD51 mark human nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion. Pubmed 1.757E-6 1.887E-3 2.025E-2 4.528E-2 3 7
24 20446891:gr A comprehensive study of the association between the EGFR and ERBB2 genes and glioma risk. GeneRIF 1.757E-6 1.887E-3 2.025E-2 4.528E-2 3 7
25 19948975:gr Integrative predictive model of coronary artery calcification in atherosclerosis. GeneRIF 2.618E-6 2.595E-3 2.785E-2
6.747E-2
 8 229
26 19948975 Integrative predictive model of coronary artery calcification in atherosclerosis. Pubmed 2.618E-6 2.595E-3 2.785E-2
6.747E-2
 8 229
27 8681137 Identification of 4370 expressed sequence tags from a 3'-end-specific cDNA library of human skeletal muscle by DNA sequencing and filter hybridization. Pubmed 4.108E-6 2.658E-3 2.853E-2
1.058E-1
 4 29
28 11866539 Identification of endothelial cell genes expressed in an in vitro model of angiogenesis: induction of ESM-1, (beta)ig-h3, and NrCAM. Pubmed 4.195E-6 2.658E-3 2.853E-2
1.081E-1
 3 9
29 23620752 The diminished expression of proangiogenic growth factors and their receptors in gastric ulcers of cirrhotic patients. Pubmed 4.195E-6 2.658E-3 2.853E-2
1.081E-1
 3 9
30 19936222 Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis. Pubmed 5.410E-6 2.658E-3 2.853E-2
1.394E-1
 4 31
31 20673868:gr A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). GeneRIF 7.144E-6 2.658E-3 2.853E-2
1.841E-1
 7 187
32 20673868 A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). Pubmed 7.144E-6 2.658E-3 2.853E-2
1.841E-1
 7 187
33 20452482:gr Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. GeneRIF 7.398E-6 2.658E-3 2.853E-2
1.906E-1
 7 188
34 20452482 Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. Pubmed 7.398E-6 2.658E-3 2.853E-2
1.906E-1
 7 188
35 19032382:gr Antigen expression of human eccrine sweat glands. GeneRIF 8.195E-6 2.658E-3 2.853E-2
2.111E-1
 3 11
36 19032382 Antigen expression of human eccrine sweat glands. Pubmed 8.195E-6 2.658E-3 2.853E-2
2.111E-1
 3 11
37 20602615 Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? Pubmed 8.486E-6 2.658E-3 2.853E-2
2.186E-1
 7 192
38 20602615:gr Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? GeneRIF 8.486E-6 2.658E-3 2.853E-2
2.186E-1
 7 192
39 23563607 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Pubmed 9.568E-6 2.658E-3 2.853E-2
2.465E-1
 6 129
40 20587546:gr Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection. GeneRIF 9.982E-6 2.658E-3 2.853E-2
2.572E-1
 4 36
41 20587546 Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection. Pubmed 9.982E-6 2.658E-3 2.853E-2
2.572E-1
 4 36
42 20864672:gr Genetic variants influencing circulating lipid levels and risk of coronary artery disease. GeneRIF 1.090E-5 2.658E-3 2.853E-2
2.807E-1
 3 12
43 15846844 Proteomic profiling of cellular proteins interacting with the hepatitis C virus core protein. Pubmed 1.090E-5 2.658E-3 2.853E-2
2.807E-1
 3 12
44 24658140 The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Pubmed 1.139E-5 2.658E-3 2.853E-2
2.935E-1
 6 133
45 20503287 Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. Pubmed 1.258E-5 2.658E-3 2.853E-2
3.241E-1
 7 204
46 20503287:gr Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. GeneRIF 1.258E-5 2.658E-3 2.853E-2
3.241E-1
 7 204
47 19258923 Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. Pubmed 1.298E-5 2.658E-3 2.853E-2
3.345E-1
 7 205
48 19258923:gr Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. GeneRIF 1.298E-5 2.658E-3 2.853E-2
3.345E-1
 7 205
49 24915158 Intestinal cell barrier function in vitro is severely compromised by keratin 8 and 18 mutations identified in patients with inflammatory bowel disease. Pubmed 1.378E-5 2.658E-3 2.853E-2
3.551E-1
 2 2
50 22412904:gr Non-coding keratin variants associate with liver fibrosis progression in patients with hemochromatosis. GeneRIF 1.378E-5 2.658E-3 2.853E-2
3.551E-1
 2 2
Show 45 more annotations

9: Interaction [Display Chart] 3053 annotations before applied cutoff / 16534 genes in category

No results to display

10: Cytoband [Display Chart] 158 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1q32 1q32 1.528E-4 1.827E-2
1.031E-1
 2.415E-2 4 49
2 5q13 5q13 2.312E-4 1.827E-2
1.031E-1
 3.653E-2 3 22
3 4q32.1 4q32.1 4.304E-4 2.267E-2
1.279E-1
6.800E-2
 3 27

11: Transcription Factor Binding Site [Display Chart] 491 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$EN1 01 V$EN1 01 1.041E-4 3.811E-2
2.582E-1
5.111E-2
 7 91
2 V$GATA1 03 V$GATA1 03 1.552E-4 3.811E-2
2.582E-1
7.622E-2
 10 203

12: Gene Family [Display Chart] 102 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 471 CD molecules|V-set domain containing|Immunoglobulin like domain containing|Carcinoembryonic antigen related cell adhesion molecule family genenames.org 2.812E-5 2.868E-3 1.494E-2 2.868E-3 12 394
2 593 CD molecules|V-set domain containing|I-set domain containing|Sialic acid binding Ig like lectins genenames.org 1.661E-4 6.524E-3 3.397E-2 1.695E-2 7 161
3 321 Receptor Tyrosine Kinases|Fibronectin type III domain containing|V-set domain containing|Immunoglobulin like domain containing genenames.org 1.919E-4 6.524E-3 3.397E-2 1.957E-2 4 40
4 219 F2R receptors genenames.org 3.058E-4 7.798E-3 4.060E-2 3.119E-2 2 4
5 556 Fibulins genenames.org 1.400E-3 2.857E-2
1.487E-1
1.428E-1
 2 8
6 594 CD molecules|V-set domain containing|Immunoglobulin like domain containing genenames.org 2.754E-3 4.681E-2
2.438E-1
2.809E-1
 6 193
Show 1 more annotation

13: Coexpression [Display Chart] 6557 annotations before applied cutoff / 21867 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M4306 Genes down-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.036E-15 6.792E-12 6.361E-11 6.792E-12 28 464
2 M12138 Genes up-regulated in erythroid lineage cells by RUNX1-RUNX1T1 [GeneID=861;862] fusion . MSigDB C2: CGP Curated Gene Sets (v5.1) 4.896E-14 1.605E-10 1.503E-9 3.210E-10 17 157
3 M4680 Genes up-regulated in RD cells (embryonal rhabdomyosarcoma, ERMS) by expression of PAX3- or PAX7-FOXO1 [GeneID=5077;5081;2308] fusions off retroviral vectors. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.366E-12 2.985E-9 2.796E-8 8.955E-9 19 255
4 M13206 Genes down-regulated in TC71 and EWS502 cells (Ewing's sarcoma) by EWSR1-FLI1 [GeneID=2130;2314] as inferred from RNAi knockdown of this fusion protein. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.838E-11 1.365E-7 1.279E-6 6.451E-7 19 326
5 M3804 Genes up-regulated in normal hematopoietic progenitors by RUNX1-RUNX1T1 [GeneID=861;862] fusion. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.041E-10 1.365E-7 1.279E-6 6.827E-7 15 185
6 M4995 Genes specifically up-regulated in Cluster IIb of urothelial cell carcinom (UCC) tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.981E-10 3.258E-7 3.051E-6 1.955E-6 20 390
7 M12225 Up-regulated genes in angioimmunoblastic lymphoma (AILT) compared to normal T lymphocytes. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.415E-10 4.135E-7 3.873E-6 2.895E-6 15 205
8 M1804 Genes up-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [GeneID=6605] off a retroviral vector. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.330E-10 4.369E-7 4.092E-6 3.495E-6 17 280
9 M1578 Genes down-regulated in freshly isolated CD31- [GeneID=5175] (stromal stem cells from adipose tissue) versus the CD31+ (non-stem) counterparts. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.132E-10 6.653E-7 6.231E-6 5.988E-6 15 216
10 M15835 Genes down-regulated SUM44/LCCTam cells (breast cancer) resistant to 4-hydroxytamoxifen [PubChem=63062] relative to the parental SUM44 cells sensitive to the drug. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.177E-9 7.718E-7 7.228E-6 7.718E-6 15 220
11 M17923 Genes up-regulated in cultured stromal stem cells from adipose tissue, compared to the freshly isolated cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.326E-9 7.907E-7 7.405E-6 8.698E-6 20 425
12 M3645 Genes up-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.700E-9 1.475E-6 1.382E-5 1.770E-5 20 443
13 M12085 Genes up-regulated by RUNX1-RUNX1T1 [GeneID=861;862] fusion protein in normal hematopoietic progenitors; their expression was sustained in subsequently developing erythroid lineage. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.300E-9 2.169E-6 2.031E-5 2.819E-5 8 44
14 M2446 Genes down-regulated in MEF cells (embryonic fibroblast) upon stimulation with TGFB1 [GeneID=7040] for 10 h. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.858E-9 2.276E-6 2.131E-5 3.186E-5 15 244
15 M12621 Genes up-regulated in Wilm's tumor samples compared to fetal kidney. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.906E-9 3.761E-6 3.522E-5 5.840E-5 13 182
16 M2581 Genes up-regulated in the HSC supportive stromal cell lines. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.687E-9 3.761E-6 3.522E-5 6.352E-5 16 297
17 M15981 Genes up-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.750E-9 3.761E-6 3.522E-5 6.393E-5 19 430
18 M2256 Genes commonly down-regulated in UET-13 cells (mesenchymal progenitor) by expression of EWSR1 [GeneID=2130] fusions with ETS transcription factors FLI1 and ERG [GeneID=2313 ,2078]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.544E-8 5.626E-6 5.269E-5 1.013E-4 14 227
19 M9192 Genes down-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.866E-8 9.890E-6 9.263E-5 1.879E-4 19 460
20 M6510 Genes up-regulated in post-GC, BCL6 [GeneID=604] dependent B cell non-Hodgkin's lymphoma (B-NHL) vs MYC [GeneID=4609] driven pre-GC lymphoma. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.540E-8 1.161E-5 1.087E-4 2.321E-4 15 283
21 M1565 Genes up-regulated in MMEC cells (myometrial endothelium) by VEGFA [GeneID=7422] stimulation. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.157E-8 1.298E-5 1.216E-4 2.726E-4 10 108
22 M2205 Genes up-regulated in immature bone marrow progenitor cells upon knock out of CBFA2T3 [GeneID=863]. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.605E-8 1.968E-5 1.844E-4 4.331E-4 17 387
23 M19097 Genes up-regulated in the Kras2LA mouse lung cancer model with mutated KRAS [GeneID=3845]. MSigDB C2: CGP Curated Gene Sets (v5.1) 7.992E-8 2.278E-5 2.134E-4 5.240E-4 19 491
24 M2001 Genes associated with migration rate of 40 human bladder cancer cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.213E-8 2.437E-5 2.282E-4 6.041E-4 12 184
25 M5547 Age up-regulated genes in the human frontal cortex. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.290E-8 2.437E-5 2.282E-4 6.091E-4 14 262
26 M13273 Genes down-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.568E-7 3.953E-5 3.703E-4 1.028E-3 13 232
27 M5930 Genes defining epithelial-mesenchymal transition, as in wound healing, fibrosis and metastasis. MSigDB H: Hallmark Gene Sets (v5.1) 2.284E-7 5.348E-5 5.009E-4 1.498E-3 12 200
28 GSE36888 UNTREATED VS IL2 TREATED TCELL 17H UP Genes up-regulated in T cells: control versus IL2 [GeneID=3558] stimulation for 17h. MSigDB C7: Immunologic Signatures (v5.1) 2.284E-7 5.348E-5 5.009E-4 1.498E-3 12 200
29 M10117 Genes down-regulated in acute myeloid leukemia (AML) patients with mutated NPM1 [GeneID=4869]. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.076E-7 6.955E-5 6.514E-4 2.017E-3 13 246
30 M7514 Genes down-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [GeneID=387] off plasmid vector. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.687E-7 1.024E-4 9.594E-4 3.073E-3 16 394
31 M17471 Genes up-regulated in invasive ductal carcinoma (IDC) relative to ductal carcinoma in situ (DCIS, non-invasive). MSigDB C2: CGP Curated Gene Sets (v5.1) 5.717E-7 1.191E-4 1.115E-3 3.748E-3 15 351
32 M9483 Genes up-regulated in metastatic vs non-metastatic stromal cells originated from either bone or prostate tissues. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.812E-7 1.191E-4 1.115E-3 3.811E-3 9 110
33 M1919 Genes up-regulated in MEF cells (embryonic fibroblast) with double knockout of the translation repressors 4EBP1 [GeneID=1978] and 4EBP2 [GeneID=1979]. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.831E-7 1.357E-4 1.271E-3 4.479E-3 15 356
34 M8544 Up-regualted genes from the set F (Fig. 5a): specific signature shared by cells expressing AF4-MLL [GeneID=4299;4297] alone and those expressing both AF4-MLL and MLL-AF4 fusion proteins. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.060E-7 1.554E-4 1.456E-3 5.285E-3 11 185
35 M1521 Genes up-regulated in MMEC cells (myometrial endothelium) at 6 h after VEGFA [GeneID=7422] stimulation. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.660E-7 1.577E-4 1.477E-3 5.679E-3 7 59
36 M15107 Genes up-regulated in CD133+ [GeneID=8842] cells (hematopoietic stem cells, HSC) compared to the CD133- cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.661E-7 1.577E-4 1.477E-3 5.679E-3 14 315
37 M988 Genes up-regulated in T98G cells (glioblastoma) by TNC [GeneID=3371]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.093E-6 1.937E-4 1.814E-3 7.168E-3 10 153
38 M3654 Genes up-regulated in samples with systolic heart failure compared to normal hearts. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.157E-6 1.997E-4 1.870E-3 7.589E-3 16 422
39 M19467 Genes down-regulated in five primary endothelial cell types (lung, aortic, iliac, dermal, and colon) by TNF [GeneID=7124]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.330E-6 2.237E-4 2.095E-3 8.723E-3 8 90
40 M13661 The 'group 5 set' of genes associated with acquired endocrine therapy resistance in breast tumors expressing ESR1 but not ERBB2 [GeneID=2099;2064]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.427E-6 2.319E-4 2.172E-3 9.357E-3 17 482
41 M1784 Genes changed in U373-MG cells (malignant glioma) upon treatment with arsenic trioxide [PubChem=14888], a chemical that can cause autophagic cell death. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.493E-6 2.319E-4 2.172E-3 9.787E-3 9 123
42 M12362 Genes up-regulated in RMS cells (rhabdomyosarcoma) expressing PAX3 or PAX7 fusions with FOXO1 [GeneID=5077;5081;2308] compared to the fusion negative cell lines. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.519E-6 2.319E-4 2.172E-3 9.963E-3 7 64
43 M7137 Genes most down-regulated in hypoxia tolerant NCI H460 cells (lung cancer). MSigDB C2: CGP Curated Gene Sets (v5.1) 1.521E-6 2.319E-4 2.172E-3 9.971E-3 6 41
44 M14877 Genes down-regulated in SKOC-3 cells (ovarian cancer) after YB-1 (YBX1) [GeneID=4904] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.698E-6 2.419E-4 2.266E-3 1.113E-2 15 383
45 M7396 Genes down-regulated in the Kras2LA mouse lung cancer model with mutated KRAS [GeneID=3845]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.717E-6 2.419E-4 2.266E-3 1.126E-2 16 435
46 M6480 Genes up-regulated in monocyte-derived dendritic cells: untreated versus LPS (3h). MSigDB C7: Immunologic Signatures (v5.1) 1.734E-6 2.419E-4 2.266E-3 1.137E-2 11 200
47 M3599 Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 48 h after stimulation with IL12. MSigDB C7: Immunologic Signatures (v5.1) 1.734E-6 2.419E-4 2.266E-3 1.137E-2 11 200
48 M12272 Genes up-regulated in PaCa44 and CFPAC1 cells (pancreatic cancer) after treatment with decitabine [PubChem=451668], a DNA hypomethylating agent similar to azacitidine [PubChem=9444]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.826E-6 2.443E-4 2.288E-3 1.197E-2 9 126
49 M15887 Genes up-regulated in adipose tissue mesenchymal stem cells (ASC) vs bone marrow mesenchymal stem cells (rBMSC) MSigDB C2: CGP Curated Gene Sets (v5.1) 1.826E-6 2.443E-4 2.288E-3 1.197E-2 9 126
50 M4577 Top genes down-regulated in mesenchyme stem cells (MSC) grown in a tumor conditioned medium, which leads to carcinoma-associated fibroblast phenotype. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.886E-6 2.470E-4 2.313E-3 1.237E-2 5 24
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 3578 annotations before applied cutoff / 20974 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GSM777037 500 Stromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 3.349E-18 1.198E-14 1.050E-13 1.198E-14 31 459
2 gudmap dev gonad e11.5 M GonadVasMes Flk 500 dev gonad e11.5 M GonadVasMes Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 2.156E-16 3.857E-13 3.379E-12 7.714E-13 28 419
3 Lungmap Mouse e16.5 Endothelial Top 500 All Mouse Lung E16.5 Endothelial top 500 Lungmap Mouse Single Cell (Lungmap.net) 1.064E-15 1.269E-12 1.112E-11 3.807E-12 28 446
4 GSM777032 500 Stromal Cells, BEC.MLN, gp38- CD31+, Lymph Node, avg-5 Immgen.org, GSE15907 1.868E-15 1.671E-12 1.464E-11 6.683E-12 28 456
5 GSM777043 500 Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3 Immgen.org, GSE15907 8.307E-15 5.944E-12 5.207E-11 2.972E-11 27 445
6 gudmap dev gonad e12.5 M gudmap devVasTestis Flk 500 dev gonad e12.5 M DevVasTestis Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.209E-14 7.211E-12 6.317E-11 4.327E-11 26 414
7 Facebase RNAseq e10.5 Olfactory Pit 1000 K1 FacebaseRNAseq e10.5 Olfactory Pit top-relative-expression-ranked 1000 k-means-cluster#1 FaceBase_RNAseq 3.538E-14 1.809E-11 1.584E-10 1.266E-10 21 259
8 gudmap dev gonad e11.5 M GonadVasMes Flk k1 1000 dev gonad e11.5 M GonadVasMes Flk k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 8.480E-14 3.793E-11 3.322E-10 3.034E-10 23 338
9 26Dn Top 500 All 26Dn Top 500 All Brain Map - Allen iN 1.137E-13 4.520E-11 3.960E-10 4.068E-10 27 496
10 gudmap dev gonad e11.5 F GonadVasMes Flk 500 dev gonad e11.5 F GonadVasMes Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.687E-13 6.038E-11 5.289E-10 6.038E-10 25 424
11 gudmap kidney e10.5 UretericTrunk HoxB7 500 kidney e10.5 UretericTrunk HoxB7 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 2.953E-13 9.607E-11 8.415E-10 1.057E-9 24 396
12 gudmap dev gonad e13.5 M InterstitTestis Sma 500 dev gonad e13.5 M InterstitTestis Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 3.581E-13 1.068E-10 9.352E-10 1.281E-9 23 362
13 gudmap dev gonad e13.5 F VascAssocMesenchStromOvary Sma 500 dev gonad e13.5 F VascAssocMesenchStromOvary Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 6.677E-13 1.605E-10 1.406E-9 2.389E-9 23 373
14 54Dn Top 500 All 54Dn Top 500 All Brain Map - Allen iN 6.967E-13 1.605E-10 1.406E-9 2.493E-9 26 493
15 gudmap kidney e15.5 Podocyte MafB 500 kidney e15.5 Podocyte MafB top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 7.300E-13 1.605E-10 1.406E-9 2.612E-9 24 413
16 gudmap kidney e15.5 SmlBldVes Tie2 500 kidney e15.5 SmlBldVes Tie2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 7.300E-13 1.605E-10 1.406E-9 2.612E-9 24 413
17 PCBC ratio EB blastocyst vs EB amniotic fluid MSC cfr-2X-p05 EB blastocyst vs EB amniotic fluid MSC-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 7.624E-13 1.605E-10 1.406E-9 2.728E-9 21 303
18 gudmap dev gonad e11.5 M GonadVasMes Flk k4 500 dev gonad e11.5 M GonadVasMes Flk k-means-cluster#4 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 8.530E-13 1.696E-10 1.485E-9 3.052E-9 18 208
19 gudmap dev gonad e13.5 M gudmap devVasTestis Flk 500 dev gonad e13.5 M DevVasTestis Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.728E-12 3.254E-10 2.851E-9 6.183E-9 24 430
20 GSM777059 500 Stromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 2.683E-12 4.800E-10 4.204E-9 9.599E-9 24 439
21 gudmap dev gonad e11.5 F ReproVasc Flk 500 dev gonad e11.5 F ReproVasc Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 4.451E-12 7.363E-10 6.450E-9 1.593E-8 23 409
22 GSM777063 500 Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 4.527E-12 7.363E-10 6.450E-9 1.620E-8 24 450
23 gudmap dev gonad e13.5 F gudmap devVascOvary Flk 500 dev gonad e13.5 F DevVascOvary Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 6.290E-12 9.785E-10 8.572E-9 2.251E-8 23 416
24 Lungmap Mouse e16.5 Endothelial SubClass Mature Endothelial Top 500 All Mouse Lung E16.5 Mature Endothelial top500 Lungmap Mouse Single Cell (Lungmap.net) 6.935E-12 1.034E-9 9.056E-9 2.481E-8 23 418
25 gudmap dev gonad e12.5 F VasAssMesen MafB 500 dev gonad e12.5 F VasAssMesen MafB top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.200E-11 1.717E-9 1.504E-8 4.294E-8 22 389
26 gudmap dev gonad e11.5 F ReproVasc Flk k3 1000 dev gonad e11.5 F ReproVasc Flk k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 2.347E-11 3.230E-9 2.829E-8 8.397E-8 23 444
27 Facebase RNAseq e10.5 Olfactory Pit 500 FacebaseRNAseq e10.5 Olfactory Pit top-relative-expression-ranked 500 FaceBase_RNAseq 3.313E-11 4.390E-9 3.846E-8 1.185E-7 24 495
28 gudmap dev gonad e12.5 M InterstitTestis Sma 500 dev gonad e12.5 M InterstitTestis Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 4.141E-11 5.219E-9 4.572E-8 1.482E-7 21 374
29 gudmap dev gonad e12.5 M gudmap devVasTestis Flk k2 500 dev gonad e12.5 M DevVasTestis Flk k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 4.238E-11 5.219E-9 4.572E-8 1.516E-7 19 298
30 ratio EB vs SC 1000 K1 ratio EmbryoidBody vs StemCell top-relative-expression-ranked 1000 k-means-cluster#1 PCBC 4.376E-11 5.219E-9 4.572E-8 1.566E-7 20 336
31 PCBC ratio MESO-5 vs DE cfr-2X-p05 Mesoderm Day 5 vs Endoderm Differentiated Cells-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 5.131E-11 5.922E-9 5.188E-8 1.836E-7 20 339
32 gudmap dev gonad e12.5 F VasAssocMesStromOvary Sma 500 dev gonad e12.5 F VasAssocMesStromOvary Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 7.440E-11 8.319E-9 7.288E-8 2.662E-7 21 386
33 gudmap dev gonad e11.5 M GonMes Sma k3 1000 dev gonad e11.5 M GonMes Sma k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 9.314E-11 1.010E-8 8.847E-8 3.333E-7 19 312
34 gudmap dev gonad e11.5 F GonadVasMes Flk k3 1000 dev gonad e11.5 F GonadVasMes Flk k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 1.166E-10 1.227E-8 1.075E-7 4.173E-7 20 355
35 gudmap kidney e10.5 UretericTrunk HoxB7 200 kidney e10.5 UretericTrunk HoxB7 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 1.275E-10 1.303E-8 1.142E-7 4.561E-7 14 151
36 gudmap dev gonad e12.5 M gudmap devVasTestis Flk k2 200 dev gonad e12.5 M DevVasTestis Flk k-means-cluster#2 top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 1.973E-10 1.960E-8 1.717E-7 7.058E-7 14 156
37 PCBC ratio DE vs SC 500 ratio induced-DefinitiveEndoderm vs StemCell top-relative-expression-ranked 500 PCBC 2.378E-10 2.299E-8 2.014E-7 8.508E-7 23 499
38 gudmap dev gonad e12.5 F gudmap devVasOvary Flk 500 dev gonad e12.5 F DevVasOvary Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 2.814E-10 2.649E-8 2.321E-7 1.007E-6 21 415
39 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 k4 1000 dev lower uro neuro e15.5 PelvicGanglion Sox10 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 3.376E-10 3.097E-8 2.713E-7 1.208E-6 17 261
40 Facebase RNAseq e9.5 Olfactory Placode 2500 K5 FacebaseRNAseq e9.5 Olfactory Placode top-relative-expression-ranked 2500 k-means-cluster#5 FaceBase_RNAseq 6.361E-10 5.690E-8 4.984E-7 2.276E-6 20 391
41 gudmap dev gonad e12.5 F gudmap devVasOvary Flk 200 dev gonad e12.5 F DevVasOvary Flk top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 9.757E-10 8.515E-8 7.459E-7 3.491E-6 14 176
42 gudmap dev gonad e13.5 M gudmap devVasTestis Flk k4 500 dev gonad e13.5 M DevVasTestis Flk k-means-cluster#4 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.108E-9 9.435E-8 8.265E-7 3.963E-6 17 282
43 Facebase RNAseq e9.5 Olfactory Placode 1000 K3 FacebaseRNAseq e9.5 Olfactory Placode top-relative-expression-ranked 1000 k-means-cluster#3 FaceBase_RNAseq 1.169E-9 9.727E-8 8.521E-7 4.183E-6 17 283
44 Facebase RNAseq e10.5 Olfactory Pit 2500 K5 FacebaseRNAseq e10.5 Olfactory Pit top-relative-expression-ranked 2500 k-means-cluster#5 FaceBase_RNAseq 1.221E-9 9.925E-8 8.694E-7 4.368E-6 20 406
45 gudmap dev gonad e12.5 M InterstitLeydig MafB 500 dev gonad e12.5 M InterstitLeydig MafB top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.248E-9 9.925E-8 8.694E-7 4.466E-6 19 364
46 gudmap dev gonad e12.5 M gudmap devVasTestis Flk 200 dev gonad e12.5 M DevVasTestis Flk top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 1.310E-9 1.009E-7 8.836E-7 4.688E-6 14 180
47 26Dn SubClass 26Dn 2 Top 500 All 26Dn SubClass 26Dn 2 Top 500 All Brain Map - Allen iN 1.325E-9 1.009E-7 8.836E-7 4.741E-6 22 498
48 gudmap dev gonad e11.5 F ReproVasc Flk 200 dev gonad e11.5 F ReproVasc Flk top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 1.514E-9 1.105E-7 9.683E-7 5.417E-6 14 182
49 gudmap dev gonad e11.5 M ReproVasc Flk 200 dev gonad e11.5 M ReproVasc Flk top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 1.514E-9 1.105E-7 9.683E-7 5.417E-6 14 182
50 gudmap dev gonad e11.5 M ReproVasc Flk 500 dev gonad e11.5 M ReproVasc Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.708E-9 1.222E-7 1.071E-6 6.111E-6 20 414
Show 45 more annotations

15: Computational [Display Chart] 357 annotations before applied cutoff / 9399 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 module 52 Genes in module 52 MSigDb: C4 - CM: Cancer Modules 2.543E-7 4.735E-5 3.057E-4 9.077E-5 21 419
2 module 47 Genes in module 47 MSigDb: C4 - CM: Cancer Modules 2.653E-7 4.735E-5 3.057E-4 9.470E-5 15 216
3 module 1 Genes in module 1 MSigDb: C4 - CM: Cancer Modules 2.163E-6 2.574E-4 1.662E-3 7.723E-4 18 361
4 module 180 Genes in module 180 MSigDb: C4 - CM: Cancer Modules 3.646E-6 2.611E-4 1.686E-3 1.302E-3 10 114
5 module 342 Genes in module 342 MSigDb: C4 - CM: Cancer Modules 3.657E-6 2.611E-4 1.686E-3 1.306E-3 13 200
6 module 5 Genes in module 5 MSigDb: C4 - CM: Cancer Modules 5.126E-6 3.050E-4 1.969E-3 1.830E-3 19 423
7 module 139 Genes in module 139 MSigDb: C4 - CM: Cancer Modules 7.484E-5 3.817E-3 2.464E-2 2.672E-2 7 75
8 module 33 Genes in module 33 MSigDb: C4 - CM: Cancer Modules 1.838E-4 8.203E-3
5.296E-2
6.563E-2
 15 372
9 module 2 Genes in module 2 MSigDb: C4 - CM: Cancer Modules 2.188E-4 8.680E-3
5.604E-2
7.812E-2
 15 378
10 module 121 Genes in module 121 MSigDb: C4 - CM: Cancer Modules 4.011E-4 1.432E-2
9.245E-2
1.432E-1
 7 98
11 module 357 Genes in module 357 MSigDb: C4 - CM: Cancer Modules 7.592E-4 2.464E-2
1.591E-1
2.710E-1
 6 79
12 module 19 Genes in module 19 MSigDb: C4 - CM: Cancer Modules 1.092E-3 3.004E-2
1.940E-1
3.899E-1
 12 307
13 module 118 Genes in module 118 MSigDb: C4 - CM: Cancer Modules 1.094E-3 3.004E-2
1.940E-1
3.905E-1
 14 395
14 module 6 Genes in module 6 MSigDb: C4 - CM: Cancer Modules 1.455E-3 3.710E-2
2.395E-1
5.194E-1
 14 407
Show 9 more annotations

16: MicroRNA [Display Chart] 1298 annotations before applied cutoff / 19844 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-338-3p:TargetScan hsa-miR-338-3p:TargetScan TargetScan 2.287E-5 9.211E-3
7.135E-2
 2.968E-2 10 198
2 hsa-miR-199b-3p:PITA hsa-miR-199b-3p:PITA TOP PITA 3.343E-5 9.211E-3
7.135E-2
 4.340E-2 12 298
3 hsa-miR-199a-3p:PITA hsa-miR-199a-3p:PITA TOP PITA 3.343E-5 9.211E-3
7.135E-2
 4.340E-2 12 298
4 hsa-miR-196a:TargetScan hsa-miR-196a:TargetScan TargetScan 3.780E-5 9.211E-3
7.135E-2
 4.906E-2 10 210
5 hsa-miR-196b:TargetScan hsa-miR-196b:TargetScan TargetScan 3.780E-5 9.211E-3
7.135E-2
 4.906E-2 10 210
6 hsa-miR-219-5p:PITA hsa-miR-219-5p:PITA TOP PITA 4.477E-5 9.211E-3
7.135E-2
5.812E-2
 9 172
7 hsa-miR-4322:mirSVR highEffct hsa-miR-4322:mirSVR nonconserved highEffect-0.5 MicroRNA.org 5.258E-5 9.211E-3
7.135E-2
6.825E-2
 15 470
8 hsa-miR-222:PITA hsa-miR-222:PITA TOP PITA 6.428E-5 9.211E-3
7.135E-2
8.344E-2
 11 270
9 hsa-miR-219-5p:TargetScan hsa-miR-219-5p:TargetScan TargetScan 6.867E-5 9.211E-3
7.135E-2
8.914E-2
 11 272
10 hsa-miR-221:PITA hsa-miR-221:PITA TOP PITA 7.097E-5 9.211E-3
7.135E-2
9.211E-2
 11 273
11 hsa-miR-129-5p:PITA hsa-miR-129-5p:PITA TOP PITA 7.833E-5 9.243E-3
7.160E-2
1.017E-1
 15 487
12 hsa-miR-212:PITA hsa-miR-212:PITA TOP PITA 1.116E-4 1.071E-2
8.299E-2
1.448E-1
 12 338
13 hsa-miR-132:PITA hsa-miR-132:PITA TOP PITA 1.116E-4 1.071E-2
8.299E-2
1.448E-1
 12 338
14 hsa-miR-4265:mirSVR highEffct hsa-miR-4265:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.170E-4 1.071E-2
8.299E-2
1.519E-1
 14 448
15 hsa-miR-196a:PITA hsa-miR-196a:PITA TOP PITA 1.321E-4 1.071E-2
8.299E-2
1.714E-1
 9 198
16 hsa-miR-196b:PITA hsa-miR-196b:PITA TOP PITA 1.321E-4 1.071E-2
8.299E-2
1.714E-1
 9 198
17 hsa-miR-660:PITA hsa-miR-660:PITA TOP PITA 2.188E-4 1.240E-2
9.608E-2
2.840E-1
 8 167
18 CAATGCA,MIR-33:MSigDB CAATGCA,MIR-33:MSigDB MSigDB 2.341E-4 1.240E-2
9.608E-2
3.038E-1
 6 90
19 miR-199a-star:PicTar miR-199a-star:PicTar PicTar 2.359E-4 1.240E-2
9.608E-2
3.063E-1
 13 422
20 hsa-miR-623:PITA hsa-miR-623:PITA TOP PITA 2.549E-4 1.240E-2
9.608E-2
3.309E-1
 7 129
21 hsa-let-7g:PITA hsa-let-7g:PITA TOP PITA 2.771E-4 1.240E-2
9.608E-2
3.597E-1
 12 373
22 hsa-let-7e:PITA hsa-let-7e:PITA TOP PITA 2.771E-4 1.240E-2
9.608E-2
3.597E-1
 12 373
23 hsa-let-7c:PITA hsa-let-7c:PITA TOP PITA 2.771E-4 1.240E-2
9.608E-2
3.597E-1
 12 373
24 hsa-let-7b:PITA hsa-let-7b:PITA TOP PITA 2.771E-4 1.240E-2
9.608E-2
3.597E-1
 12 373
25 hsa-let-7f:PITA hsa-let-7f:PITA TOP PITA 2.771E-4 1.240E-2
9.608E-2
3.597E-1
 12 373
26 hsa-let-7a:PITA hsa-let-7a:PITA TOP PITA 2.771E-4 1.240E-2
9.608E-2
3.597E-1
 12 373
27 hsa-let-7d:PITA hsa-let-7d:PITA TOP PITA 2.771E-4 1.240E-2
9.608E-2
3.597E-1
 12 373
28 hsa-let-7i:PITA hsa-let-7i:PITA TOP PITA 2.771E-4 1.240E-2
9.608E-2
3.597E-1
 12 373
29 hsa-miR-98:PITA hsa-miR-98:PITA TOP PITA 2.771E-4 1.240E-2
9.608E-2
3.597E-1
 12 373
30 miR-144:PicTar miR-144:PicTar PicTar 3.022E-4 1.308E-2
1.013E-1
3.923E-1
 13 433
31 GACAATC,MIR-219:MSigDB GACAATC,MIR-219:MSigDB MSigDB 3.216E-4 1.347E-2
1.043E-1
4.174E-1
 7 134
32 hsa-miR-455-5p:PITA hsa-miR-455-5p:PITA TOP PITA 3.679E-4 1.470E-2
1.138E-1
4.775E-1
 7 137
33 hsa-miR-4296:mirSVR highEffct hsa-miR-4296:mirSVR nonconserved highEffect-0.5 MicroRNA.org 3.757E-4 1.470E-2
1.138E-1
4.877E-1
 13 443
34 hsa-miR-31:miRTarbase hsa-miR-31:miRTarbase miRTarbase 3.850E-4 1.470E-2
1.138E-1
4.997E-1
 4 36
35 hsa-miR-33a:PITA hsa-miR-33a:PITA TOP PITA 4.014E-4 1.477E-2
1.144E-1
5.211E-1
 9 230
36 hsa-miR-33b:PITA hsa-miR-33b:PITA TOP PITA 4.143E-4 1.477E-2
1.144E-1
5.377E-1
 9 231
37 TACTTGA,MIR-26A:MSigDB TACTTGA,MIR-26A:MSigDB MSigDB 4.325E-4 1.477E-2
1.144E-1
5.614E-1
 10 283
38 TACTTGA,MIR-26B:MSigDB TACTTGA,MIR-26B:MSigDB MSigDB 4.325E-4 1.477E-2
1.144E-1
5.614E-1
 10 283
39 hsa-miR-205:TargetScan hsa-miR-205:TargetScan TargetScan 4.959E-4 1.619E-2
1.254E-1
6.436E-1
 10 288
40 hsa-miR-217:TargetScan hsa-miR-217:TargetScan TargetScan 4.988E-4 1.619E-2
1.254E-1
6.475E-1
 9 237
41 hsa-miR-219-2-3p:PITA hsa-miR-219-2-3p:PITA TOP PITA 5.202E-4 1.647E-2
1.276E-1
6.752E-1
 8 190
42 hsa-miR-587:PITA hsa-miR-587:PITA TOP PITA 7.163E-4 1.975E-2
1.530E-1
9.298E-1
 12 415
43 hsa-miR-124:miRecords TarBase hsa-miR-124:miRecords TarBase miRecords_TarBase 7.284E-4 1.975E-2
1.530E-1
9.455E-1
 8 200
44 miR-199b:PicTar miR-199b:PicTar PicTar 7.284E-4 1.975E-2
1.530E-1
9.455E-1
 8 200
45 GACTGTT,MIR-132:MSigDB GACTGTT,MIR-132:MSigDB MSigDB 7.405E-4 1.975E-2
1.530E-1
9.612E-1
 7 154
46 GACTGTT,MIR-212:MSigDB GACTGTT,MIR-212:MSigDB MSigDB 7.405E-4 1.975E-2
1.530E-1
9.612E-1
 7 154
47 hsa-miR-484:PITA hsa-miR-484:PITA TOP PITA 7.405E-4 1.975E-2
1.530E-1
9.612E-1
 7 154
48 hsa-miR-557:PITA hsa-miR-557:PITA TOP PITA 7.526E-4 1.975E-2
1.530E-1
9.769E-1
 10 304
49 hsa-miR-507:PITA hsa-miR-507:PITA TOP PITA 7.526E-4 1.975E-2
1.530E-1
9.769E-1
 10 304
50 GCAAGAC,MIR-431:MSigDB GCAAGAC,MIR-431:MSigDB MSigDB 7.654E-4 1.975E-2
1.530E-1
9.934E-1
 4 43
Show 45 more annotations

17: Drug [Display Chart] 20601 annotations before applied cutoff / 22098 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 4072 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 5.266E-11 1.085E-6 1.140E-5 1.085E-6 15 180
2 1212 UP Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 2.763E-10 2.583E-6 2.715E-5 5.692E-6 14 170
3 2084 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 3.761E-10 2.583E-6 2.715E-5 7.749E-6 14 174
4 2904 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT HG-U133A Broad Institute CMAP 1.117E-9 5.754E-6 6.047E-5 2.302E-5 14 189
5 1793 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 2.823E-9 1.119E-5 1.176E-4 5.815E-5 13 169
6 3791 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 3.259E-9 1.119E-5 1.176E-4 6.713E-5 13 171
7 D008942 Mitoxantrone CTD 4.328E-9 1.192E-5 1.252E-4 8.915E-5 15 247
8 4565 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 4.628E-9 1.192E-5 1.252E-4 9.533E-5 13 176
9 7084 UP MS-275; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 7.421E-9 1.699E-5 1.785E-4 1.529E-4 13 183
10 6143 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT HG-U133A Broad Institute CMAP 1.027E-8 1.923E-5 2.021E-4 2.115E-4 13 188
11 5882 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 1.027E-8 1.923E-5 2.021E-4 2.115E-4 13 188
12 D008558 Melphalan CTD 2.121E-8 3.227E-5 3.392E-4 4.370E-4 15 278
13 7046 DN PHA-00846566E [724718-26-7]; Down 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 2.153E-8 3.227E-5 3.392E-4 4.435E-4 13 200
14 4444 UP SAHA; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 2.193E-8 3.227E-5 3.392E-4 4.518E-4 12 165
15 4237 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 3.266E-8 4.486E-5 4.715E-4 6.729E-4 12 171
16 7077 UP trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 3.717E-8 4.654E-5 4.891E-4 7.657E-4 12 173
17 2507 UP Tetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; HL60; HT HG-U133A Broad Institute CMAP 4.222E-8 4.654E-5 4.891E-4 8.699E-4 12 175
18 3746 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 4.222E-8 4.654E-5 4.891E-4 8.699E-4 12 175
19 4665 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 4.789E-8 4.654E-5 4.891E-4 9.865E-4 12 177
20 4590 UP Etilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; PC3; HT HG-U133A Broad Institute CMAP 4.789E-8 4.654E-5 4.891E-4 9.865E-4 12 177
21 5065 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 5.096E-8 4.654E-5 4.891E-4 1.050E-3 12 178
22 C058705 diethyl malate CTD 5.212E-8 4.654E-5 4.891E-4 1.074E-3 9 85
23 5086 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 5.422E-8 4.654E-5 4.891E-4 1.117E-3 12 179
24 4184 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 5.422E-8 4.654E-5 4.891E-4 1.117E-3 12 179
25 3290 DN Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; MCF7; HT HG-U133A Broad Institute CMAP 6.129E-8 4.791E-5 5.036E-4 1.263E-3 12 181
26 C002202 4-oxoretinoic acid CTD 6.244E-8 4.791E-5 5.036E-4 1.286E-3 10 115
27 C459179 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide CTD 6.419E-8 4.791E-5 5.036E-4 1.322E-3 11 147
28 6316 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 6.512E-8 4.791E-5 5.036E-4 1.342E-3 12 182
29 7074 UP MS-275; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 7.345E-8 5.217E-5 5.484E-4 1.513E-3 12 184
30 6709 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 8.772E-8 6.024E-5 6.331E-4 1.807E-3 12 187
31 5579 UP radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT HG-U133A Broad Institute CMAP 1.044E-7 6.939E-5 7.293E-4 2.151E-3 12 190
32 4442 UP 17-AAG; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 1.171E-7 7.537E-5 7.922E-4 2.412E-3 12 192
33 D010705 Phosgene CTD 1.344E-7 8.389E-5 8.817E-4 2.768E-3 11 158
34 4685 DN Timolol maleate salt [26921-17-5]; Down 200; 9.2uM; PC3; HT HG-U133A Broad Institute CMAP 1.466E-7 8.866E-5 9.318E-4 3.020E-3 12 196
35 1220 UP SAHA; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP 1.527E-7 8.866E-5 9.318E-4 3.146E-3 11 160
36 7434 DN Pergolide mesylate [66104-23-2]; Down 200; 9.8uM; MCF7; HT HG-U133A Broad Institute CMAP 1.549E-7 8.866E-5 9.318E-4 3.192E-3 12 197
37 2988 DN Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; HL60; HT HG-U133A Broad Institute CMAP 1.826E-7 1.016E-4 1.068E-3 3.761E-3 12 200
38 2540 UP Podophyllotoxin [518-28-5]; Up 200; 9.6uM; HL60; HT HG-U133A Broad Institute CMAP 2.218E-7 1.202E-4 1.264E-3 4.569E-3 11 166
39 1234 UP Trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 2.357E-7 1.245E-4 1.308E-3 4.855E-3 11 167
40 C103303 alitretinoin CTD 2.714E-7 1.398E-4 1.469E-3 5.591E-3 14 292
41 2105 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 3.362E-7 1.689E-4 1.775E-3 6.926E-3 11 173
42 7245 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 3.773E-7 1.807E-4 1.900E-3 7.772E-3 11 175
43 3873 UP Rifabutin [72559-06-9]; Up 200; 4.8uM; MCF7; HT HG-U133A Broad Institute CMAP 3.773E-7 1.807E-4 1.900E-3 7.772E-3 11 175
44 5209 UP Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT HG-U133A Broad Institute CMAP 4.227E-7 1.893E-4 1.990E-3 8.708E-3 11 177
45 3993 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 4.227E-7 1.893E-4 1.990E-3 8.708E-3 11 177
46 7555 UP trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 4.227E-7 1.893E-4 1.990E-3 8.708E-3 11 177
47 5940 UP trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP 4.472E-7 1.960E-4 2.060E-3 9.213E-3 11 178
48 4248 UP Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Up 200; 7.6uM; PC3; HT HG-U133A Broad Institute CMAP 4.729E-7 2.020E-4 2.123E-3 9.743E-3 11 179
49 6340 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 5.000E-7 2.020E-4 2.123E-3 1.030E-2 11 180
50 3787 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 5.000E-7 2.020E-4 2.123E-3 1.030E-2 11 180
Show 45 more annotations

18: Disease [Display Chart] 2325 annotations before applied cutoff / 16150 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 umls:C1800706 Idiopathic Pulmonary Fibrosis DisGeNET Curated 1.947E-6 4.526E-3 3.770E-2 4.526E-3 15 323
2 umls:C0003090 Ankylosis DisGeNET Curated 2.046E-5 2.379E-2
1.981E-1
 4.757E-2 4 16
3 umls:C1334177 Infiltrating Cervical Carcinoma DisGeNET BeFree 4.572E-5 2.919E-2
2.431E-1
1.063E-1
 6 61
4 umls:C1335475 Primary Carcinoma DisGeNET BeFree 1.003E-4 2.919E-2
2.431E-1
2.332E-1
 5 44
5 umls:C0037286 Skin Neoplasms DisGeNET Curated 1.082E-4 2.919E-2
2.431E-1
2.516E-1
 10 216
6 umls:C1861556 Cirrhosis, Familial DisGeNET Curated 1.128E-4 2.919E-2
2.431E-1
2.622E-1
 2 2
7 215600 CIRRHOSIS, FAMILIAL OMIM 1.128E-4 2.919E-2
2.431E-1
2.622E-1
 2 2
8 umls:C0019189 Hepatitis, Chronic DisGeNET Curated 1.184E-4 2.919E-2
2.431E-1
2.753E-1
 9 177
9 umls:C0162820 Dermatitis, Allergic Contact DisGeNET Curated 1.227E-4 2.919E-2
2.431E-1
2.853E-1
 7 104
10 umls:C0555198 Malignant Glioma DisGeNET BeFree 1.351E-4 2.919E-2
2.431E-1
3.141E-1
 14 412
11 umls:C0206727 Nerve Sheath Tumors DisGeNET Curated 1.381E-4 2.919E-2
2.431E-1
3.210E-1
 5 47
12 umls:C0853879 Invasive breast carcinoma DisGeNET BeFree 1.653E-4 3.204E-2
2.668E-1
3.844E-1
 13 369
13 umls:C0022408 Arthropathy DisGeNET Curated 1.844E-4 3.297E-2
2.746E-1
4.286E-1
 7 111
14 umls:C0027830 neurofibroma DisGeNET Curated 2.043E-4 3.393E-2
2.826E-1
4.750E-1
 5 51
15 umls:C0024899 Mastocytosis DisGeNET Curated 2.241E-4 3.457E-2
2.880E-1
5.211E-1
 5 52
16 umls:C0278883 Metastatic melanoma DisGeNET BeFree 2.405E-4 3.457E-2
2.880E-1
5.591E-1
 12 333
17 umls:C0339543 Epiretinal Membrane DisGeNET BeFree 2.742E-4 3.457E-2
2.880E-1
6.376E-1
 4 30
18 umls:C0035126 Reperfusion Injury DisGeNET Curated 2.918E-4 3.457E-2
2.880E-1
6.784E-1
 6 85
19 umls:C0278488 Carcinoma breast stage IV DisGeNET BeFree 2.986E-4 3.457E-2
2.880E-1
6.942E-1
 12 341
20 umls:C1292778 Chronic myeloproliferative disorder DisGeNET BeFree 3.047E-4 3.457E-2
2.880E-1
7.085E-1
 8 159
21 umls:C0220726 Diastrophic dysplasia DisGeNET Curated 3.123E-4 3.457E-2
2.880E-1
7.260E-1
 4 31
22 umls:C0035238 Congenital abnormality of respiratory system DisGeNET Curated 3.359E-4 3.550E-2
2.957E-1
7.811E-1
 2 3
23 umls:C0949690 Spondylarthritis DisGeNET Curated 3.753E-4 3.731E-2
3.107E-1
8.727E-1
 5 58
24 umls:C0018798 Congenital Heart Defects DisGeNET Curated 3.944E-4 3.731E-2
3.107E-1
9.170E-1
 9 208
25 umls:C0008925 Cleft Palate DisGeNET Curated 4.011E-4 3.731E-2
3.107E-1
9.326E-1
 7 126
Show 20 more annotations