1: GO: Molecular Function [Display Chart]
577 annotations before applied cutoff / 18819 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
GO:0009922
|
fatty acid elongase activity
|
|
9.129E-6
|
5.267E-3
|
3.653E-2
|
5.267E-3
|
3
|
7
|
2
|
GO:0004312
|
fatty acid synthase activity
|
|
4.223E-5
|
1.218E-2
|
8.450E-2
|
2.436E-2
|
3
|
11
|
3
|
GO:0048037
|
cofactor binding
|
|
8.374E-5
|
1.611E-2
|
1.117E-1
|
4.832E-2
|
9
|
278
|
4
|
GO:0051015
|
actin filament binding
|
|
2.396E-4
|
2.366E-2
|
1.641E-1
|
1.382E-1
|
6
|
134
|
5
|
GO:0004720
|
protein-lysine 6-oxidase activity
|
|
2.480E-4
|
2.366E-2
|
1.641E-1
|
1.431E-1
|
2
|
4
|
6
|
GO:0050662
|
coenzyme binding
|
|
2.654E-4
|
2.366E-2
|
1.641E-1
|
1.531E-1
|
7
|
193
|
7
|
GO:0031625
|
ubiquitin protein ligase binding
|
|
4.096E-4
|
2.366E-2
|
1.641E-1
|
2.363E-1
|
8
|
273
|
8
|
GO:0008823
|
cupric reductase activity
|
|
4.116E-4
|
2.366E-2
|
1.641E-1
|
2.375E-1
|
2
|
5
|
9
|
GO:0052851
|
ferric-chelate reductase (NADPH) activity
|
|
4.116E-4
|
2.366E-2
|
1.641E-1
|
2.375E-1
|
2
|
5
|
10
|
GO:0046912
|
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
|
|
4.116E-4
|
2.366E-2
|
1.641E-1
|
2.375E-1
|
2
|
5
|
11
|
GO:0044389
|
ubiquitin-like protein ligase binding
|
|
4.511E-4
|
2.366E-2
|
1.641E-1
|
2.603E-1
|
8
|
277
|
12
|
GO:0016215
|
acyl-CoA desaturase activity
|
|
8.569E-4
|
4.120E-2
|
2.858E-1
|
4.945E-1
|
2
|
7
|
13
|
GO:0043177
|
organic acid binding
|
|
1.045E-3
|
4.636E-2
|
3.216E-1
|
6.027E-1
|
7
|
243
|
14
|
GO:0016717
|
oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
|
|
1.138E-3
|
4.689E-2
|
3.252E-1
|
6.565E-1
|
2
|
8
|
Show 9 more annotations
|
2: GO: Biological Process [Display Chart]
2497 annotations before applied cutoff / 18785 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
GO:0016126
|
sterol biosynthetic process
|
|
3.164E-17
|
7.901E-14
|
6.637E-13
|
7.901E-14
|
13
|
56
|
2
|
GO:1902653
|
secondary alcohol biosynthetic process
|
|
4.592E-16
|
3.822E-13
|
3.211E-12
|
1.147E-12
|
12
|
51
|
3
|
GO:0006695
|
cholesterol biosynthetic process
|
|
4.592E-16
|
3.822E-13
|
3.211E-12
|
1.147E-12
|
12
|
51
|
4
|
GO:0016125
|
sterol metabolic process
|
|
4.606E-14
|
2.875E-11
|
2.415E-10
|
1.150E-10
|
15
|
148
|
5
|
GO:0008202
|
steroid metabolic process
|
|
2.279E-13
|
1.138E-10
|
9.562E-10
|
5.691E-10
|
19
|
316
|
6
|
GO:0046165
|
alcohol biosynthetic process
|
|
2.579E-12
|
1.073E-9
|
9.016E-9
|
6.440E-9
|
14
|
160
|
7
|
GO:0008203
|
cholesterol metabolic process
|
|
4.757E-12
|
1.697E-9
|
1.425E-8
|
1.188E-8
|
13
|
135
|
8
|
GO:1902652
|
secondary alcohol metabolic process
|
|
7.592E-12
|
2.370E-9
|
1.990E-8
|
1.896E-8
|
13
|
140
|
9
|
GO:0006694
|
steroid biosynthetic process
|
|
1.033E-10
|
2.866E-8
|
2.408E-7
|
2.579E-7
|
13
|
172
|
10
|
GO:0006066
|
alcohol metabolic process
|
|
1.954E-10
|
4.879E-8
|
4.098E-7
|
4.879E-7
|
18
|
411
|
11
|
GO:1901617
|
organic hydroxy compound biosynthetic process
|
|
6.617E-10
|
1.502E-7
|
1.262E-6
|
1.652E-6
|
14
|
242
|
12
|
GO:0033489
|
cholesterol biosynthetic process via desmosterol
|
|
1.091E-6
|
2.095E-4
|
1.760E-3
|
2.723E-3
|
3
|
4
|
13
|
GO:0033490
|
cholesterol biosynthetic process via lathosterol
|
|
1.091E-6
|
2.095E-4
|
1.760E-3
|
2.723E-3
|
3
|
4
|
14
|
GO:0036109
|
alpha-linolenic acid metabolic process
|
|
1.196E-6
|
2.132E-4
|
1.791E-3
|
2.985E-3
|
4
|
13
|
15
|
GO:0006633
|
fatty acid biosynthetic process
|
|
5.326E-6
|
8.866E-4
|
7.447E-3
|
1.330E-2
|
8
|
146
|
16
|
GO:0035338
|
long-chain fatty-acyl-CoA biosynthetic process
|
|
6.882E-6
|
1.074E-3
|
9.023E-3
|
1.719E-2
|
5
|
41
|
17
|
GO:0046949
|
fatty-acyl-CoA biosynthetic process
|
|
8.748E-6
|
1.285E-3
|
1.079E-2
|
2.184E-2
|
5
|
43
|
18
|
GO:0035336
|
long-chain fatty-acyl-CoA metabolic process
|
|
1.099E-5
|
1.524E-3
|
1.280E-2
|
2.744E-2
|
5
|
45
|
19
|
GO:0006732
|
coenzyme metabolic process
|
|
1.319E-5
|
1.733E-3
|
1.456E-2
|
3.293E-2
|
11
|
336
|
20
|
GO:0035337
|
fatty-acyl-CoA metabolic process
|
|
2.254E-5
|
2.814E-3
|
2.363E-2
|
5.627E-2
|
5
|
52
|
21
|
GO:0008299
|
isoprenoid biosynthetic process
|
|
3.662E-5
|
4.355E-3
|
3.658E-2
|
9.145E-2
|
4
|
29
|
22
|
GO:0006631
|
fatty acid metabolic process
|
|
4.089E-5
|
4.469E-3
|
3.754E-2
|
1.021E-1
|
11
|
380
|
23
|
GO:0046394
|
carboxylic acid biosynthetic process
|
|
4.295E-5
|
4.469E-3
|
3.754E-2
|
1.072E-1
|
10
|
315
|
24
|
GO:0016053
|
organic acid biosynthetic process
|
|
4.295E-5
|
4.469E-3
|
3.754E-2
|
1.072E-1
|
10
|
315
|
25
|
GO:0071616
|
acyl-CoA biosynthetic process
|
|
5.326E-5
|
5.115E-3
|
4.296E-2
|
1.330E-1
|
5
|
62
|
26
|
GO:0035384
|
thioester biosynthetic process
|
|
5.326E-5
|
5.115E-3
|
4.296E-2
|
1.330E-1
|
5
|
62
|
27
|
GO:0030497
|
fatty acid elongation
|
|
7.468E-5
|
6.907E-3
|
5.802E-2
|
1.865E-1
|
3
|
13
|
28
|
GO:0051186
|
cofactor metabolic process
|
|
8.443E-5
|
7.415E-3
|
6.229E-2
|
2.108E-1
|
11
|
412
|
29
|
GO:0031668
|
cellular response to extracellular stimulus
|
|
8.625E-5
|
7.415E-3
|
6.229E-2
|
2.154E-1
|
8
|
215
|
30
|
GO:0072330
|
monocarboxylic acid biosynthetic process
|
|
8.909E-5
|
7.415E-3
|
6.229E-2
|
2.225E-1
|
8
|
216
|
31
|
GO:0097286
|
iron ion import
|
|
9.460E-5
|
7.620E-3
|
6.401E-2
|
2.362E-1
|
3
|
14
|
32
|
GO:0034625
|
fatty acid elongation, monounsaturated fatty acid
|
|
1.270E-4
|
9.789E-3
|
8.223E-2
|
3.172E-1
|
2
|
3
|
33
|
GO:0015682
|
ferric iron transport
|
|
1.333E-4
|
9.789E-3
|
8.223E-2
|
3.328E-1
|
4
|
40
|
34
|
GO:0072512
|
trivalent inorganic cation transport
|
|
1.333E-4
|
9.789E-3
|
8.223E-2
|
3.328E-1
|
4
|
40
|
35
|
GO:0043651
|
linoleic acid metabolic process
|
|
1.441E-4
|
1.028E-2
|
8.639E-2
|
3.599E-1
|
3
|
16
|
36
|
GO:0031669
|
cellular response to nutrient levels
|
|
1.905E-4
|
1.322E-2
|
1.110E-1
|
4.758E-1
|
7
|
181
|
37
|
GO:0009267
|
cellular response to starvation
|
|
2.057E-4
|
1.388E-2
|
1.166E-1
|
5.137E-1
|
6
|
129
|
38
|
GO:0019322
|
pentose biosynthetic process
|
|
2.530E-4
|
1.662E-2
|
1.396E-1
|
6.317E-1
|
2
|
4
|
39
|
GO:0061041
|
regulation of wound healing
|
|
2.739E-4
|
1.754E-2
|
1.473E-1
|
6.839E-1
|
6
|
136
|
40
|
GO:0009108
|
coenzyme biosynthetic process
|
|
2.963E-4
|
1.807E-2
|
1.518E-1
|
7.398E-1
|
6
|
138
|
41
|
GO:0001676
|
long-chain fatty acid metabolic process
|
|
2.968E-4
|
1.807E-2
|
1.518E-1
|
7.411E-1
|
5
|
89
|
42
|
GO:0042493
|
response to drug
|
|
3.238E-4
|
1.925E-2
|
1.617E-1
|
8.084E-1
|
11
|
481
|
43
|
GO:0055129
|
L-proline biosynthetic process
|
|
4.198E-4
|
2.230E-2
|
1.874E-1
|
1.000E0
|
2
|
5
|
44
|
GO:0019368
|
fatty acid elongation, unsaturated fatty acid
|
|
4.198E-4
|
2.230E-2
|
1.874E-1
|
1.000E0
|
2
|
5
|
45
|
GO:0019367
|
fatty acid elongation, saturated fatty acid
|
|
4.198E-4
|
2.230E-2
|
1.874E-1
|
1.000E0
|
2
|
5
|
46
|
GO:0097461
|
ferric iron import into cell
|
|
4.198E-4
|
2.230E-2
|
1.874E-1
|
1.000E0
|
2
|
5
|
47
|
GO:0033216
|
ferric iron import
|
|
4.198E-4
|
2.230E-2
|
1.874E-1
|
1.000E0
|
2
|
5
|
48
|
GO:0006637
|
acyl-CoA metabolic process
|
|
4.855E-4
|
2.474E-2
|
2.078E-1
|
1.000E0
|
5
|
99
|
49
|
GO:0035383
|
thioester metabolic process
|
|
4.855E-4
|
2.474E-2
|
2.078E-1
|
1.000E0
|
5
|
99
|
50
|
GO:0044272
|
sulfur compound biosynthetic process
|
|
6.186E-4
|
3.081E-2
|
2.588E-1
|
1.000E0
|
7
|
220
|
Show 45 more annotations
|
3: GO: Cellular Component [Display Chart]
258 annotations before applied cutoff / 19172 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
GO:0030176
|
integral component of endoplasmic reticulum membrane
|
|
2.912E-4
|
4.553E-2
|
2.792E-1
|
7.513E-2
|
6
|
137
|
2
|
GO:0031227
|
intrinsic component of endoplasmic reticulum membrane
|
|
3.530E-4
|
4.553E-2
|
2.792E-1
|
9.107E-2
|
6
|
142
|
|
4: Human Phenotype [Display Chart]
453 annotations before applied cutoff / 4410 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
HP:0003465
|
Elevated 8(9)-cholestenol
|
|
4.783E-5
|
1.083E-2
|
7.252E-2
|
2.167E-2
|
2
|
2
|
2
|
HP:0003462
|
Elevated 8-dehydrocholesterol
|
|
4.783E-5
|
1.083E-2
|
7.252E-2
|
2.167E-2
|
2
|
2
|
3
|
HP:0001776
|
Bilateral talipes equinovarus
|
|
1.429E-4
|
2.157E-2
|
1.444E-1
|
6.472E-2
|
2
|
3
|
4
|
HP:0006685
|
Endocardial fibrosis
|
|
2.845E-4
|
3.222E-2
|
2.157E-1
|
1.289E-1
|
2
|
4
|
|
5: Mouse Phenotype [Display Chart]
2259 annotations before applied cutoff / 9299 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
MP:0002139
|
abnormal hepatobiliary system physiology
|
|
2.596E-5
|
3.954E-2
|
3.282E-1
|
5.863E-2
|
14
|
434
|
2
|
MP:0002625
|
heart left ventricle hypertrophy
|
|
3.501E-5
|
3.954E-2
|
3.282E-1
|
7.909E-2
|
6
|
70
|
3
|
MP:0010579
|
increased heart left ventricle size
|
|
5.951E-5
|
4.089E-2
|
3.394E-1
|
1.344E-1
|
7
|
112
|
4
|
MP:0009888
|
palatal shelves fail to meet at midline
|
|
8.539E-5
|
4.089E-2
|
3.394E-1
|
1.929E-1
|
5
|
51
|
5
|
MP:0003717
|
pallor
|
|
1.070E-4
|
4.089E-2
|
3.394E-1
|
2.417E-1
|
9
|
212
|
6
|
MP:0012776
|
abnormal liver cholesterol level
|
|
1.126E-4
|
4.089E-2
|
3.394E-1
|
2.543E-1
|
5
|
54
|
7
|
MP:0010578
|
abnormal heart left ventricle size
|
|
1.385E-4
|
4.089E-2
|
3.394E-1
|
3.128E-1
|
7
|
128
|
8
|
MP:0008944
|
decreased sensitivity to induced cell death
|
|
1.629E-4
|
4.089E-2
|
3.394E-1
|
3.680E-1
|
6
|
92
|
9
|
MP:0010901
|
abnormal pulmonary alveolar parenchyma morphology
|
|
1.629E-4
|
4.089E-2
|
3.394E-1
|
3.680E-1
|
6
|
92
|
10
|
MP:0000609
|
abnormal liver physiology
|
|
2.018E-4
|
4.559E-2
|
3.784E-1
|
4.559E-1
|
12
|
399
|
11
|
MP:0000010
|
abnormal abdominal fat pad morphology
|
|
2.405E-4
|
4.765E-2
|
3.955E-1
|
5.432E-1
|
9
|
236
|
12
|
MP:0001178
|
pulmonary hypoplasia
|
|
2.531E-4
|
4.765E-2
|
3.955E-1
|
5.719E-1
|
5
|
64
|
Show 7 more annotations
|
6: Domain [Display Chart]
1028 annotations before applied cutoff / 18735 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
PS01188
|
ELO
|
PROSITE
|
1.019E-5
|
3.493E-3
|
2.624E-2
|
1.048E-2
|
3
|
7
|
2
|
PF01151
|
ELO
|
Pfam
|
1.019E-5
|
3.493E-3
|
2.624E-2
|
1.048E-2
|
3
|
7
|
3
|
IPR002076
|
ELO fam
|
InterPro
|
1.019E-5
|
3.493E-3
|
2.624E-2
|
1.048E-2
|
3
|
7
|
|
7: Pathway [Display Chart]
753 annotations before applied cutoff / 10916 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
SMP00023
|
Steroid Biosynthesis
|
SMPDB
|
3.474E-18
|
2.616E-15
|
1.884E-14
|
2.616E-15
|
11
|
21
|
2
|
PW:0000454
|
cholesterol biosynthetic
|
Pathway Ontology
|
5.673E-17
|
1.844E-14
|
1.328E-13
|
4.272E-14
|
10
|
18
|
3
|
142269
|
superpathway of cholesterol biosynthesis
|
BioSystems: BIOCYC
|
7.347E-17
|
1.844E-14
|
1.328E-13
|
5.532E-14
|
11
|
26
|
4
|
106142
|
Cholesterol biosynthesis
|
BioSystems: REACTOME
|
8.151E-16
|
1.534E-13
|
1.105E-12
|
6.137E-13
|
10
|
22
|
5
|
198809
|
Cholesterol biosynthesis
|
BioSystems: WikiPathways
|
5.093E-13
|
7.670E-11
|
5.524E-10
|
3.835E-10
|
8
|
17
|
6
|
82937
|
Steroid biosynthesis
|
BioSystems: KEGG
|
2.584E-12
|
3.243E-10
|
2.336E-9
|
1.946E-9
|
8
|
20
|
7
|
142268
|
cholesterol biosynthesis III (via desmosterol)
|
BioSystems: BIOCYC
|
4.605E-12
|
3.853E-10
|
2.775E-9
|
3.467E-9
|
7
|
13
|
8
|
142266
|
cholesterol biosynthesis II (via 24,25-dihydrolanosterol)
|
BioSystems: BIOCYC
|
4.605E-12
|
3.853E-10
|
2.775E-9
|
3.467E-9
|
7
|
13
|
9
|
142267
|
cholesterol biosynthesis I
|
BioSystems: BIOCYC
|
4.605E-12
|
3.853E-10
|
2.775E-9
|
3.467E-9
|
7
|
13
|
10
|
219802
|
SREBP signalling
|
BioSystems: WikiPathways
|
3.290E-9
|
2.478E-7
|
1.784E-6
|
2.478E-6
|
9
|
64
|
11
|
685551
|
Regulation of Cholesterol Biosynthesis by SREBP (SREBF)
|
BioSystems: REACTOME
|
1.442E-8
|
9.869E-7
|
7.107E-6
|
1.086E-5
|
8
|
53
|
12
|
413390
|
Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol
|
BioSystems: KEGG
|
1.886E-8
|
1.052E-6
|
7.573E-6
|
1.420E-5
|
5
|
11
|
13
|
SMP00089
|
Pravastatin Pathway
|
SMPDB
|
3.212E-8
|
1.052E-6
|
7.573E-6
|
2.419E-5
|
5
|
12
|
14
|
SMP00119
|
Fluvastatin Pathway
|
SMPDB
|
3.212E-8
|
1.052E-6
|
7.573E-6
|
2.419E-5
|
5
|
12
|
15
|
SMP00092
|
Rosuvastatin Pathway
|
SMPDB
|
3.212E-8
|
1.052E-6
|
7.573E-6
|
2.419E-5
|
5
|
12
|
16
|
SMP00079
|
Ibandronate Pathway
|
SMPDB
|
3.212E-8
|
1.052E-6
|
7.573E-6
|
2.419E-5
|
5
|
12
|
17
|
SMP00095
|
Alendronate pathway
|
SMPDB
|
3.212E-8
|
1.052E-6
|
7.573E-6
|
2.419E-5
|
5
|
12
|
18
|
SMP00099
|
Lovastatin Pathway
|
SMPDB
|
3.212E-8
|
1.052E-6
|
7.573E-6
|
2.419E-5
|
5
|
12
|
19
|
SMP00112
|
Risedronate Pathway
|
SMPDB
|
3.212E-8
|
1.052E-6
|
7.573E-6
|
2.419E-5
|
5
|
12
|
20
|
SMP00107
|
Zoledronate Pathway
|
SMPDB
|
3.212E-8
|
1.052E-6
|
7.573E-6
|
2.419E-5
|
5
|
12
|
21
|
SMP00131
|
Atorvastatin Pathway
|
SMPDB
|
3.212E-8
|
1.052E-6
|
7.573E-6
|
2.419E-5
|
5
|
12
|
22
|
SMP00111
|
Cerivastatin Pathway
|
SMPDB
|
3.212E-8
|
1.052E-6
|
7.573E-6
|
2.419E-5
|
5
|
12
|
23
|
SMP00117
|
Pamidronate Pathway
|
SMPDB
|
3.212E-8
|
1.052E-6
|
7.573E-6
|
2.419E-5
|
5
|
12
|
24
|
685552
|
Activation of Gene Expression by SREBP (SREBF)
|
BioSystems: REACTOME
|
4.142E-8
|
1.299E-6
|
9.358E-6
|
3.119E-5
|
7
|
40
|
25
|
PW:0000248
|
steroid biosynthetic
|
Pathway Ontology
|
6.287E-7
|
1.894E-5
|
1.364E-4
|
4.734E-4
|
4
|
9
|
26
|
83034
|
Biosynthesis of unsaturated fatty acids
|
BioSystems: KEGG
|
7.762E-7
|
2.248E-5
|
1.619E-4
|
5.845E-4
|
5
|
21
|
27
|
413387
|
C5 isoprenoid biosynthesis, mevalonate pathway
|
BioSystems: KEGG
|
1.041E-6
|
2.799E-5
|
2.016E-4
|
7.838E-4
|
4
|
10
|
28
|
MAP00100 Sterol biosynthesis
|
MAP00100 Sterol biosynthesis
|
GenMAPP
|
1.041E-6
|
2.799E-5
|
2.016E-4
|
7.838E-4
|
4
|
10
|
29
|
P00014
|
Cholesterol biosynthesis
|
PantherDB
|
1.625E-6
|
4.078E-5
|
2.937E-4
|
1.224E-3
|
4
|
11
|
30
|
142207
|
mevalonate pathway I
|
BioSystems: BIOCYC
|
1.625E-6
|
4.078E-5
|
2.937E-4
|
1.224E-3
|
4
|
11
|
31
|
PW:0000184
|
terpenoid biosynthetic
|
Pathway Ontology
|
2.458E-6
|
5.972E-5
|
4.301E-4
|
1.851E-3
|
3
|
4
|
32
|
868084
|
Fatty acid metabolism
|
BioSystems: KEGG
|
3.183E-6
|
7.490E-5
|
5.394E-4
|
2.397E-3
|
6
|
48
|
33
|
545288
|
superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)
|
BioSystems: BIOCYC
|
3.474E-6
|
7.928E-5
|
5.710E-4
|
2.616E-3
|
4
|
13
|
34
|
160977
|
Fatty acid, triacylglycerol, and ketone body metabolism
|
BioSystems: REACTOME
|
4.667E-6
|
1.034E-4
|
7.444E-4
|
3.514E-3
|
10
|
188
|
35
|
755438
|
SREBF and miR33 in cholesterol and lipid homeostasis
|
BioSystems: WikiPathways
|
1.439E-5
|
3.095E-4
|
2.229E-3
|
1.083E-2
|
4
|
18
|
36
|
106115
|
Fatty Acyl-CoA Biosynthesis
|
BioSystems: REACTOME
|
2.248E-5
|
4.702E-4
|
3.386E-3
|
1.693E-2
|
4
|
20
|
37
|
83022
|
Terpenoid backbone biosynthesis
|
BioSystems: KEGG
|
2.759E-5
|
5.614E-4
|
4.043E-3
|
2.077E-2
|
4
|
21
|
38
|
142287
|
epoxysqualene biosynthesis
|
BioSystems: BIOCYC
|
7.337E-5
|
1.454E-3
|
1.047E-2
|
5.525E-2
|
2
|
2
|
39
|
413482
|
Fatty acid biosynthesis, elongation, endoplasmic reticulum
|
BioSystems: KEGG
|
9.706E-5
|
1.874E-3
|
1.350E-2
|
7.309E-2
|
3
|
11
|
40
|
198852
|
Statin Pathway
|
BioSystems: WikiPathways
|
1.542E-4
|
2.902E-3
|
2.090E-2
|
1.161E-1
|
4
|
32
|
41
|
645344
|
alpha-linolenic acid (ALA) metabolism
|
BioSystems: REACTOME
|
1.661E-4
|
2.979E-3
|
2.145E-2
|
1.251E-1
|
3
|
13
|
42
|
645343
|
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
|
BioSystems: REACTOME
|
1.661E-4
|
2.979E-3
|
2.145E-2
|
1.251E-1
|
3
|
13
|
43
|
160978
|
Synthesis of very long-chain fatty acyl-CoAs
|
BioSystems: REACTOME
|
3.193E-4
|
5.591E-3
|
4.027E-2
|
2.404E-1
|
3
|
16
|
44
|
106114
|
Triglyceride Biosynthesis
|
BioSystems: REACTOME
|
4.493E-4
|
7.689E-3
|
5.538E-2
|
3.383E-1
|
4
|
42
|
45
|
530749
|
PPARA Activates Gene Expression
|
BioSystems: REACTOME
|
5.515E-4
|
9.229E-3
|
6.647E-2
|
4.153E-1
|
6
|
119
|
46
|
119544
|
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
|
BioSystems: REACTOME
|
6.293E-4
|
1.016E-2
|
7.315E-2
|
4.739E-1
|
6
|
122
|
47
|
198758
|
Urea cycle and metabolism of amino groups
|
BioSystems: WikiPathways
|
6.339E-4
|
1.016E-2
|
7.315E-2
|
4.774E-1
|
3
|
20
|
48
|
82934
|
Fatty acid elongation
|
BioSystems: KEGG
|
9.666E-4
|
1.516E-2
|
1.092E-1
|
7.278E-1
|
3
|
23
|
49
|
545317
|
zymosterol biosynthesis
|
BioSystems: BIOCYC
|
1.076E-3
|
1.654E-2
|
1.191E-1
|
8.103E-1
|
2
|
6
|
50
|
814926
|
Carbon metabolism
|
BioSystems: KEGG
|
1.217E-3
|
1.833E-2
|
1.320E-1
|
9.164E-1
|
5
|
93
|
Show 45 more annotations
|
8: Pubmed [Display Chart]
18603 annotations before applied cutoff / 51853 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
18660489
|
Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.
|
Pubmed
|
1.097E-29
|
1.020E-25
|
1.062E-24
|
2.041E-25
|
23
|
250
|
2
|
18660489:gr
|
Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.
|
GeneRIF
|
1.097E-29
|
1.020E-25
|
1.062E-24
|
2.041E-25
|
23
|
250
|
3
|
21319273
|
An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.
|
Pubmed
|
3.056E-10
|
1.895E-6
|
1.972E-5
|
5.685E-6
|
12
|
397
|
4
|
16009940
|
Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.
|
Pubmed
|
4.245E-9
|
1.974E-5
|
2.055E-4
|
7.896E-5
|
8
|
152
|
5
|
16806233
|
Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects.
|
Pubmed
|
1.614E-8
|
6.003E-5
|
6.248E-4
|
3.002E-4
|
6
|
67
|
6
|
20602615:gr
|
Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?
|
GeneRIF
|
2.640E-8
|
7.015E-5
|
7.301E-4
|
4.910E-4
|
8
|
192
|
7
|
20602615
|
Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?
|
Pubmed
|
2.640E-8
|
7.015E-5
|
7.301E-4
|
4.910E-4
|
8
|
192
|
8
|
17855807
|
Maternal and fetal variation in genes of cholesterol metabolism is associated with preterm delivery.
|
Pubmed
|
5.913E-8
|
1.106E-4
|
1.151E-3
|
1.100E-3
|
4
|
16
|
9
|
17855807:gr
|
Maternal and fetal variation in genes of cholesterol metabolism is associated with preterm delivery.
|
GeneRIF
|
5.913E-8
|
1.106E-4
|
1.151E-3
|
1.100E-3
|
4
|
16
|
10
|
25852190
|
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.
|
Pubmed
|
5.943E-8
|
1.106E-4
|
1.151E-3
|
1.106E-3
|
10
|
401
|
11
|
23125841
|
Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1.
|
Pubmed
|
1.519E-7
|
2.568E-4
|
2.673E-3
|
2.825E-3
|
8
|
241
|
12
|
21081666
|
Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.
|
Pubmed
|
2.551E-7
|
3.790E-4
|
3.945E-3
|
4.746E-3
|
8
|
258
|
13
|
19956635:gr
|
Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.
|
GeneRIF
|
2.852E-7
|
3.790E-4
|
3.945E-3
|
5.306E-3
|
6
|
108
|
14
|
19956635
|
Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.
|
Pubmed
|
2.852E-7
|
3.790E-4
|
3.945E-3
|
5.306E-3
|
6
|
108
|
15
|
20603810:gr
|
mRNA abundance and expression of SLC27A, ACC, SCD, FADS, LPIN, INSIG, and PPARGC1 gene isoforms in mouse mammary glands during the lactation cycle.
|
GeneRIF
|
4.868E-7
|
6.038E-4
|
6.284E-3
|
9.057E-3
|
3
|
7
|
16
|
8944226
|
Biosynthesis of triacylglycerols.
|
Pubmed
|
6.504E-7
|
7.349E-4
|
7.649E-3
|
1.210E-2
|
4
|
28
|
17
|
25147182
|
Quantitative Lys-¿-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.
|
Pubmed
|
6.716E-7
|
7.349E-4
|
7.649E-3
|
1.249E-2
|
9
|
401
|
18
|
20972250:gr
|
Genetic loci associated with lipid concentrations and cardiovascular risk factors in the Korean population.
|
GeneRIF
|
7.530E-7
|
7.373E-4
|
7.674E-3
|
1.401E-2
|
4
|
29
|
19
|
20972250
|
Genetic loci associated with lipid concentrations and cardiovascular risk factors in the Korean population.
|
Pubmed
|
7.530E-7
|
7.373E-4
|
7.674E-3
|
1.401E-2
|
4
|
29
|
20
|
16027165
|
Akt-mediated valosin-containing protein 97 phosphorylation regulates its association with ubiquitinated proteins.
|
Pubmed
|
8.672E-7
|
8.002E-4
|
8.328E-3
|
1.613E-2
|
4
|
30
|
21
|
16385451
|
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
|
Pubmed
|
9.278E-7
|
8.002E-4
|
8.328E-3
|
1.726E-2
|
9
|
417
|
22
|
16385451:gr
|
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
|
GeneRIF
|
9.463E-7
|
8.002E-4
|
8.328E-3
|
1.760E-2
|
9
|
418
|
23
|
23874603
|
HIV-1 Vpr modulates macrophage metabolic pathways: a SILAC-based quantitative analysis.
|
Pubmed
|
1.061E-6
|
8.585E-4
|
8.936E-3
|
1.975E-2
|
6
|
135
|
24
|
24797263
|
Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress.
|
Pubmed
|
1.380E-6
|
1.070E-3
|
1.114E-2
|
2.568E-2
|
8
|
323
|
25
|
23246001
|
SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation.
|
Pubmed
|
2.145E-6
|
1.535E-3
|
1.598E-2
|
3.990E-2
|
7
|
239
|
26
|
20937905
|
ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis.
|
Pubmed
|
2.279E-6
|
1.535E-3
|
1.598E-2
|
4.239E-2
|
3
|
11
|
27
|
15164054
|
The DNA sequence and comparative analysis of human chromosome 10.
|
Pubmed
|
2.398E-6
|
1.535E-3
|
1.598E-2
|
4.461E-2
|
8
|
348
|
28
|
23825951
|
Cellular RNA binding proteins NS1-BP and hnRNP K regulate influenza A virus RNA splicing.
|
Pubmed
|
2.838E-6
|
1.535E-3
|
1.598E-2
|
5.280E-2
|
4
|
40
|
29
|
18261733:gr
|
Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER.
|
GeneRIF
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
30
|
21822304
|
MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells.
|
Pubmed
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
31
|
21544602:gr
|
Increased elongase 6 and ¿9-desaturase activity are associated with n-7 and n-9 fatty acid changes in cystic fibrosis.
|
GeneRIF
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
32
|
14633995:gr
|
MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation.
|
GeneRIF
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
33
|
21383846:gr
|
Genetic variants of the FADS gene cluster and ELOVL gene family, colostrums LC-PUFA levels, breastfeeding, and child cognition.
|
GeneRIF
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
34
|
19196137:gr
|
Six-transmembrane epithelial antigen of the prostate (STEAP1 and STEAP2)-differentially expressed by murine and human mesenchymal stem cells.
|
GeneRIF
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
35
|
22024489
|
A Mediterranean-style, low-glycemic-load diet reduces the expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in mononuclear cells and plasma insulin in women with metabolic syndrome.
|
Pubmed
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
36
|
20458442
|
Tetra-glutamic acid residues adjacent to Lys248 in HMG-CoA reductase are critical for the ubiquitination mediated by gp78 and UBE2G2.
|
Pubmed
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
37
|
21383846
|
Genetic variants of the FADS gene cluster and ELOVL gene family, colostrums LC-PUFA levels, breastfeeding, and child cognition.
|
Pubmed
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
38
|
14761977:gr
|
MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53.
|
GeneRIF
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
39
|
21822304:gr
|
MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cells.
|
GeneRIF
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
40
|
19887822:gr
|
Regulation of low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression by thymoquinone-rich fraction and thymoquinone in HepG2 cells.
|
GeneRIF
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
41
|
17627285:gr
|
Ceramide-induced G2 arrest in rhabdomyosarcoma (RMS) cells requires p21Cip1/Waf1 induction and is prevented by MDM2 overexpression.
|
GeneRIF
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
42
|
3866240
|
Human genes involved in cholesterol metabolism: chromosomal mapping of the loci for the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase with cDNA probes.
|
Pubmed
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
43
|
15644444
|
The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma.
|
Pubmed
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
44
|
20308078:gr
|
MDM2 promotes proteasomal degradation of p21Waf1 via a conformation change.
|
GeneRIF
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
45
|
12901493:gr
|
Association between low-density lipoprotein receptor-related protein gene, butyrylcholinesterase gene and Alzheimer' s disease in Chinese.
|
GeneRIF
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
46
|
20979563
|
MDM2 and CDKN1A gene polymorphisms and risk of Kaposi's sarcoma in African and Caucasian patients.
|
Pubmed
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
47
|
15962316:gr
|
A20 protects mice from lethal radical hepatectomy by promoting hepatocyte proliferation via a p21waf1-dependent mechanism.
|
GeneRIF
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
48
|
18261733
|
Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER.
|
Pubmed
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
49
|
20413733
|
Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin.
|
Pubmed
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
50
|
19887822
|
Regulation of low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression by thymoquinone-rich fraction and thymoquinone in HepG2 cells.
|
Pubmed
|
5.858E-6
|
1.535E-3
|
1.598E-2
|
1.090E-1
|
2
|
2
|
Show 45 more annotations
|
9: Interaction [Display Chart]
3057 annotations before applied cutoff / 16534 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
int:TCTN3
|
TCTN3 interactions
|
|
1.811E-5
|
2.971E-2
|
2.556E-1
|
5.536E-2
|
11
|
317
|
2
|
int:ISG15
|
ISG15 interactions
|
|
1.944E-5
|
2.971E-2
|
2.556E-1
|
5.942E-2
|
9
|
208
|
|
10: Cytoband [Display Chart]
121 annotations before applied cutoff / 34661 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
5q23.2
|
5q23.2
|
|
2.585E-4
|
3.127E-2
|
1.682E-1
|
3.127E-2
|
3
|
34
|
2
|
2p13
|
2p13
|
|
3.434E-3
|
4.399E-2
|
2.365E-1
|
4.155E-1
|
2
|
24
|
3
|
1q25.1-q31.1
|
1q25.1-q31.1
|
|
3.635E-3
|
4.399E-2
|
2.365E-1
|
4.399E-1
|
1
|
1
|
4
|
4q13.3-q21.3
|
4q13.3-q21.3
|
|
3.635E-3
|
4.399E-2
|
2.365E-1
|
4.399E-1
|
1
|
1
|
5
|
18q21.1-q21.32
|
18q21.1-q21.32
|
|
3.635E-3
|
4.399E-2
|
2.365E-1
|
4.399E-1
|
1
|
1
|
6
|
12q14.3-q15
|
12q14.3-q15
|
|
3.635E-3
|
4.399E-2
|
2.365E-1
|
4.399E-1
|
1
|
1
|
7
|
11q12.2-q13.1
|
11q12.2-q13.1
|
|
3.635E-3
|
4.399E-2
|
2.365E-1
|
4.399E-1
|
1
|
1
|
8
|
10q21.3-q23.1
|
10q21.3-q23.1
|
|
3.635E-3
|
4.399E-2
|
2.365E-1
|
4.399E-1
|
1
|
1
|
9
|
14q24-q32
|
14q24-q32
|
|
3.635E-3
|
4.399E-2
|
2.365E-1
|
4.399E-1
|
1
|
1
|
10
|
10q11.1-q24
|
10q11.1-q24
|
|
3.635E-3
|
4.399E-2
|
2.365E-1
|
4.399E-1
|
1
|
1
|
11
|
Xq23-q24
|
Xq23-q24
|
|
7.257E-3
|
4.879E-2
|
2.623E-1
|
8.781E-1
|
1
|
2
|
12
|
8p23.1-p22
|
8p23.1-p22
|
|
7.257E-3
|
4.879E-2
|
2.623E-1
|
8.781E-1
|
1
|
2
|
13
|
5p14-p13
|
5p14-p13
|
|
7.257E-3
|
4.879E-2
|
2.623E-1
|
8.781E-1
|
1
|
2
|
14
|
6p21.1-p12.1
|
6p21.1-p12.1
|
|
7.257E-3
|
4.879E-2
|
2.623E-1
|
8.781E-1
|
1
|
2
|
15
|
12p12.3-p12.1
|
12p12.3-p12.1
|
|
7.257E-3
|
4.879E-2
|
2.623E-1
|
8.781E-1
|
1
|
2
|
16
|
5q13.3-q14
|
5q13.3-q14
|
|
7.257E-3
|
4.879E-2
|
2.623E-1
|
8.781E-1
|
1
|
2
|
17
|
10q23.2-q23.3
|
10q23.2-q23.3
|
|
7.257E-3
|
4.879E-2
|
2.623E-1
|
8.781E-1
|
1
|
2
|
18
|
9q34.13-q34.3
|
9q34.13-q34.3
|
|
7.257E-3
|
4.879E-2
|
2.623E-1
|
8.781E-1
|
1
|
2
|
Show 13 more annotations
|
11: Transcription Factor Binding Site [Display Chart]
473 annotations before applied cutoff / 9770 genes in category
|
12: Gene Family [Display Chart]
66 annotations before applied cutoff / 18194 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
1324
|
STEAP family
|
genenames.org
|
1.366E-4
|
9.019E-3
|
4.306E-2
|
9.019E-3
|
2
|
5
|
2
|
553
|
Fatty acid desaturases
|
genenames.org
|
3.798E-4
|
1.253E-2
|
5.985E-2
|
2.507E-2
|
2
|
8
|
3
|
759
|
StAR related lipid transfer domain containing
|
genenames.org
|
1.401E-3
|
2.979E-2
|
1.422E-1
|
9.243E-2
|
2
|
15
|
4
|
583
|
Heat shock 70kDa proteins
|
genenames.org
|
1.805E-3
|
2.979E-2
|
1.422E-1
|
1.191E-1
|
2
|
17
|
|
13: Coexpression [Display Chart]
6061 annotations before applied cutoff / 21867 genes in category
|
14: Coexpression Atlas [Display Chart]
2799 annotations before applied cutoff / 20974 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
gudmap dev gonad e13.5 M gudmap devVasTestis Flk k1 500
|
dev gonad e13.5 M DevVasTestis Flk k-means-cluster#1 top-relative-expression-ranked 500
|
Gudmap Mouse ST 1.0
|
5.889E-10
|
1.372E-6
|
1.168E-5
|
1.648E-6
|
8
|
50
|
2
|
OPC Top 500 All
|
OPC Top 500 All
|
Brain Map - Barres
|
9.804E-10
|
1.372E-6
|
1.168E-5
|
2.744E-6
|
18
|
494
|
3
|
GSM777043 500
|
Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3
|
Immgen.org, GSE15907
|
1.088E-8
|
1.015E-5
|
8.642E-5
|
3.045E-5
|
16
|
445
|
4
|
gudmap dev gonad e13.5 M gudmap devVasTestis Flk k1 1000
|
dev gonad e13.5 M DevVasTestis Flk k-means-cluster#1 top-relative-expression-ranked 1000
|
Gudmap Mouse ST 1.0
|
7.007E-8
|
4.903E-5
|
4.174E-4
|
1.961E-4
|
6
|
36
|
5
|
gudmap kidney e15.5 Podocyte MafB 500
|
kidney e15.5 Podocyte MafB top-relative-expression-ranked 500
|
Gudmap Mouse MOE430.2
|
1.969E-7
|
9.741E-5
|
8.294E-4
|
5.512E-4
|
14
|
413
|
6
|
GSM605805 500
|
gamma delta T cells, Tgd.vg5+.IEL, CD8a+ CD8b- TCRd+ Vg5+ CD44lo, Small Intestine, avg-3
|
Immgen.org, GSE15907
|
2.088E-7
|
9.741E-5
|
8.294E-4
|
5.845E-4
|
14
|
415
|
7
|
54SK Top 500 All
|
54SK Top 500 All
|
Brain Map - Allen iN
|
2.473E-7
|
9.887E-5
|
8.418E-4
|
6.921E-4
|
15
|
488
|
8
|
gudmap dev gonad e13.5 M gudmap devVasTestis Flk 500
|
dev gonad e13.5 M DevVasTestis Flk top-relative-expression-ranked 500
|
Gudmap Mouse ST 1.0
|
3.208E-7
|
1.122E-4
|
9.556E-4
|
8.979E-4
|
14
|
430
|
9
|
GSM777046 500
|
Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4
|
Immgen.org, GSE15907
|
4.004E-7
|
1.245E-4
|
1.060E-3
|
1.121E-3
|
14
|
438
|
10
|
GSM777067 500
|
Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2
|
Immgen.org, GSE15907
|
5.990E-7
|
1.468E-4
|
1.250E-3
|
1.677E-3
|
14
|
453
|
11
|
54Dn SubClass 54Dn 1SK Top 500 Cluster 2
|
54Dn SubClass 54Dn 1SK Top 500 Cluster 2
|
Brain Map - Allen iN
|
6.002E-7
|
1.468E-4
|
1.250E-3
|
1.680E-3
|
11
|
265
|
12
|
Lungmap Mouse p107 AT2 Epithelial (GSE52583) Top 500 All
|
Mouse Lung p107 Epithelial Adult AT2 top 500
|
Lungmap Mouse Single Cell (Lungmap.net)
|
6.293E-7
|
1.468E-4
|
1.250E-3
|
1.761E-3
|
13
|
388
|
13
|
GSM605811 500
|
gamma delta T cells, Tgd.vg5-.IEL, CD8a+ CD8b- TCRgd+ Vg5- CD44lo, Small Intestine, avg-3
|
Immgen.org, GSE15907
|
1.017E-6
|
2.190E-4
|
1.865E-3
|
2.847E-3
|
13
|
405
|
14
|
54Dn SubClass 54Dn 4 Top 500 All
|
54Dn SubClass 54Dn 4 Top 500 All
|
Brain Map - Allen iN
|
1.410E-6
|
2.761E-4
|
2.351E-3
|
3.947E-3
|
14
|
487
|
15
|
endothelial SubClass endothelial all Top 500 All
|
endothelial SubClass endothelial all Top 500 All
|
Brain Map - Barres
|
1.480E-6
|
2.761E-4
|
2.351E-3
|
4.141E-3
|
14
|
489
|
16
|
26Dn SubClass 26Dn 2 Top 500 All
|
26Dn SubClass 26Dn 2 Top 500 All
|
Brain Map - Allen iN
|
1.831E-6
|
3.204E-4
|
2.728E-3
|
5.126E-3
|
14
|
498
|
17
|
GSM791102 500
|
Stem Cells, SC.LT34F.BM, Lineage- cKit+ Sca-1+ flk2- CD34-, Bone marrow, avg-3
|
Immgen.org, GSE15907
|
2.116E-6
|
3.485E-4
|
2.967E-3
|
5.924E-3
|
12
|
365
|
18
|
gudmap dev gonad e13.5 M gudmap devVasTestis Flk k4 1000
|
dev gonad e13.5 M DevVasTestis Flk k-means-cluster#4 top-relative-expression-ranked 1000
|
Gudmap Mouse ST 1.0
|
3.163E-6
|
4.776E-4
|
4.067E-3
|
8.854E-3
|
8
|
148
|
19
|
gudmap dev gonad e13.5 M InterstitFLeydig MafB k2 1000
|
dev gonad e13.5 M InterstitFLeydig MafB k-means-cluster#2 top-relative-expression-ranked 1000
|
Gudmap Mouse ST 1.0
|
3.337E-6
|
4.776E-4
|
4.067E-3
|
9.339E-3
|
7
|
105
|
20
|
GSM538280 500
|
Myeloid Cells, DC.LC.Sk, MHCII+ CD11b+ CD45+, Skin, avg-2
|
Immgen.org, GSE15907
|
3.413E-6
|
4.776E-4
|
4.067E-3
|
9.553E-3
|
13
|
452
|
21
|
54Dn SubClass 54Dn 1SK Top 500 All
|
54Dn SubClass 54Dn 1SK Top 500 All
|
Brain Map - Allen iN
|
4.228E-6
|
5.636E-4
|
4.799E-3
|
1.184E-2
|
13
|
461
|
22
|
GSM777050 500
|
Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5
|
Immgen.org, GSE15907
|
4.864E-6
|
6.097E-4
|
5.191E-3
|
1.361E-2
|
13
|
467
|
23
|
gudmap developingLowerUrinaryTract e14.5 bladder 1000 k5
|
DevelopingLowerUrinaryTract e14.5 bladder emap-30872 k-means-cluster#5 top-relative-expression-ranked 1000
|
Gudmap Mouse MOE430.2
|
5.010E-6
|
6.097E-4
|
5.191E-3
|
1.402E-2
|
12
|
397
|
24
|
GSM605802 500
|
gamma delta T cells, Tgd.vg5+.act.IEL, CD8a+ CD8b- TCRd+ Vg5+ CD44hi, Small Intestine, avg-3
|
Immgen.org, GSE15907
|
6.944E-6
|
8.098E-4
|
6.895E-3
|
1.944E-2
|
12
|
410
|
25
|
fetal quiescent Top 500 All
|
fetal quiescent Top 500 All
|
Brain Map - Barres
|
7.979E-6
|
8.654E-4
|
7.368E-3
|
2.233E-2
|
13
|
489
|
26
|
GSM791146 500
|
alpha beta T cells, preT.DN3A.Th, Lin-/lo CD25hi CD44- CD28-, Thymus, avg-3
|
Immgen.org, GSE15907
|
8.038E-6
|
8.654E-4
|
7.368E-3
|
2.250E-2
|
12
|
416
|
27
|
gudmap dev gonad e11.5 M GonadVasMes Flk 500
|
dev gonad e11.5 M GonadVasMes Flk top-relative-expression-ranked 500
|
Gudmap Mouse ST 1.0
|
8.640E-6
|
8.787E-4
|
7.482E-3
|
2.418E-2
|
12
|
419
|
28
|
endothelial Top 500 All
|
endothelial Top 500 All
|
Brain Map - Barres
|
9.286E-6
|
8.787E-4
|
7.482E-3
|
2.599E-2
|
13
|
496
|
29
|
GSM399454 500
|
Stem Cells, SC.STSL.BM, CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Bone marrow, avg-3
|
Immgen.org, GSE15907
|
9.505E-6
|
8.787E-4
|
7.482E-3
|
2.660E-2
|
12
|
423
|
30
|
26Dn SubClass 26Dn 4 Top 500 Cluster 0
|
26Dn SubClass 26Dn 4 Top 500 Cluster 0
|
Brain Map - Allen iN
|
9.523E-6
|
8.787E-4
|
7.482E-3
|
2.666E-2
|
7
|
123
|
31
|
gudmap dev gonad e11.5 F GonadVasMes Flk 500
|
dev gonad e11.5 F GonadVasMes Flk top-relative-expression-ranked 500
|
Gudmap Mouse ST 1.0
|
9.732E-6
|
8.787E-4
|
7.482E-3
|
2.724E-2
|
12
|
424
|
32
|
gudmap dev gonad e13.5 F VascAssocMesenchStromOvary MafB 500
|
dev gonad e13.5 F VascAssocMesenchStromOvary MafB top-relative-expression-ranked 500
|
Gudmap Mouse ST 1.0
|
1.085E-5
|
9.490E-4
|
8.080E-3
|
3.037E-2
|
11
|
358
|
33
|
endothelial SubClass endothelial all Top 500 Cluster 3
|
endothelial SubClass endothelial all Top 500 Cluster 3
|
Brain Map - Barres
|
1.324E-5
|
1.123E-3
|
9.560E-3
|
3.705E-2
|
6
|
86
|
34
|
gudmap dev gonad e12.5 M SertoliCell Sox9 500
|
dev gonad e12.5 M SertoliCell Sox9 top-relative-expression-ranked 500
|
Gudmap Mouse ST 1.0
|
1.440E-5
|
1.176E-3
|
1.001E-2
|
4.031E-2
|
12
|
441
|
35
|
gudmap developingLowerUrinaryTract e14.5 bladder 1000 k4
|
DevelopingLowerUrinaryTract e14.5 bladder emap-30872 k-means-cluster#4 top-relative-expression-ranked 1000
|
Gudmap Mouse MOE430.2
|
1.511E-5
|
1.176E-3
|
1.001E-2
|
4.230E-2
|
7
|
132
|
36
|
gudmap kidney adult RenalCapsule k2 1000
|
kidney adult RenalCapsule k-means-cluster#2 top-relative-expression-ranked 1000
|
Gudmap Mouse MOE430.2
|
1.513E-5
|
1.176E-3
|
1.001E-2
|
4.234E-2
|
11
|
371
|
37
|
GSM777063 500
|
Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4
|
Immgen.org, GSE15907
|
1.759E-5
|
1.331E-3
|
1.133E-2
|
4.924E-2
|
12
|
450
|
38
|
Facebase RNAseq e10.5 Lateral Nasal Eminence 500 K4
|
FacebaseRNAseq e10.5 Lateral Nasal Eminence top-relative-expression-ranked 500 k-means-cluster#4
|
FaceBase_RNAseq
|
2.130E-5
|
1.569E-3
|
1.336E-2
|
5.962E-2
|
8
|
192
|
39
|
gudmap developingKidney e14.5 whole kidney - wildtype 1000 k2
|
DevelopingKidney e14.5 whole kidney - wildtype emap-6674 k-means-cluster#2 top-relative-expression-ranked 1000
|
Gudmap Mouse MOE430.2
|
2.776E-5
|
1.992E-3
|
1.696E-2
|
7.769E-2
|
7
|
145
|
40
|
54Dn SubClass 54Dn 4 Top 500 Cluster 3
|
54Dn SubClass 54Dn 4 Top 500 Cluster 3
|
Brain Map - Allen iN
|
3.283E-5
|
2.298E-3
|
1.956E-2
|
9.190E-2
|
5
|
61
|
41
|
54SK SubClass 54SK 1 Top 500 Cluster 4
|
54SK SubClass 54SK 1 Top 500 Cluster 4
|
Brain Map - Allen iN
|
3.445E-5
|
2.352E-3
|
2.003E-2
|
9.644E-2
|
4
|
31
|
42
|
GSM476663 500
|
Stem Cells, SC.LTSL.BM, CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-1
|
Immgen.org, GSE15907
|
3.701E-5
|
2.467E-3
|
2.100E-2
|
1.036E-1
|
11
|
409
|
43
|
GSM854335 500
|
alpha beta T cells, preT.ETP.Th, Lin-/lo CD25- CD44+ cKit+, Thymus, avg-3
|
Immgen.org, GSE15907
|
4.223E-5
|
2.728E-3
|
2.322E-2
|
1.182E-1
|
11
|
415
|
44
|
54Dn Top 500 All
|
54Dn Top 500 All
|
Brain Map - Allen iN
|
4.288E-5
|
2.728E-3
|
2.322E-2
|
1.200E-1
|
12
|
493
|
45
|
GSM476664 500
|
gamma delta T cells, Tgd.vg3+24alo.e17.Th, TCRd+ Vg3+ CD24-, Fetal Thymus, avg-3
|
Immgen.org, GSE15907
|
4.605E-5
|
2.865E-3
|
2.439E-2
|
1.289E-1
|
11
|
419
|
46
|
gudmap developingLowerUrinaryTract e14.5 bladder 500
|
DevelopingLowerUrinaryTract e14.5 bladder emap-30872 top-relative-expression-ranked 500
|
Gudmap Mouse MOE430.2
|
4.807E-5
|
2.925E-3
|
2.491E-2
|
1.346E-1
|
11
|
421
|
47
|
GSM538282 500
|
Myeloid Cells, MF.Lu, CD11chi CD11b- CD103- MHCII- SiglecF+, Lung, avg-3
|
Immgen.org, GSE15907
|
5.234E-5
|
3.117E-3
|
2.654E-2
|
1.465E-1
|
11
|
425
|
48
|
gudmap dev gonad e13.5 M SertoliCell Sox9 500
|
dev gonad e13.5 M SertoliCell Sox9 top-relative-expression-ranked 500
|
Gudmap Mouse ST 1.0
|
6.187E-5
|
3.608E-3
|
3.072E-2
|
1.732E-1
|
11
|
433
|
49
|
BM Top 100 - heart ventricle
|
BM Top 100 - heart ventricle
|
Body Map
|
6.850E-5
|
3.913E-3
|
3.331E-2
|
1.917E-1
|
5
|
71
|
50
|
GSM777059 500
|
Stromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4
|
Immgen.org, GSE15907
|
6.996E-5
|
3.916E-3
|
3.334E-2
|
1.958E-1
|
11
|
439
|
Show 45 more annotations
|
15: Computational [Display Chart]
392 annotations before applied cutoff / 9399 genes in category
|
16: MicroRNA [Display Chart]
1178 annotations before applied cutoff / 19844 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
miR-101:PicTar
|
miR-101:PicTar
|
PicTar
|
1.641E-5
|
1.272E-2
|
9.729E-2
|
1.933E-2
|
12
|
430
|
2
|
GTACTGT,MIR-101:MSigDB
|
GTACTGT,MIR-101:MSigDB
|
MSigDB
|
2.159E-5
|
1.272E-2
|
9.729E-2
|
2.544E-2
|
9
|
242
|
3
|
hsa-miR-646:PITA
|
hsa-miR-646:PITA TOP
|
PITA
|
9.459E-5
|
2.417E-2
|
1.848E-1
|
1.114E-1
|
11
|
437
|
4
|
ATACCTC,MIR-202:MSigDB
|
ATACCTC,MIR-202:MSigDB
|
MSigDB
|
9.716E-5
|
2.417E-2
|
1.848E-1
|
1.145E-1
|
7
|
170
|
5
|
hsa-miR-125a:miRTarbase
|
hsa-miR-125a:miRTarbase
|
miRTarbase
|
1.026E-4
|
2.417E-2
|
1.848E-1
|
1.208E-1
|
3
|
15
|
6
|
TGTGTGA,MIR-377:MSigDB
|
TGTGTGA,MIR-377:MSigDB
|
MSigDB
|
1.589E-4
|
2.808E-2
|
2.148E-1
|
1.871E-1
|
7
|
184
|
7
|
hsa-miR-489:PITA
|
hsa-miR-489:PITA TOP
|
PITA
|
2.064E-4
|
2.808E-2
|
2.148E-1
|
2.431E-1
|
7
|
192
|
8
|
hsa-miR-101:PITA
|
hsa-miR-101:PITA TOP
|
PITA
|
2.106E-4
|
2.808E-2
|
2.148E-1
|
2.481E-1
|
11
|
479
|
9
|
GGCAGTG,MIR-324-3P:MSigDB
|
GGCAGTG,MIR-324-3P:MSigDB
|
MSigDB
|
2.156E-4
|
2.808E-2
|
2.148E-1
|
2.540E-1
|
5
|
87
|
10
|
hsa-miR-376a:PITA
|
hsa-miR-376a:PITA TOP
|
PITA
|
3.076E-4
|
2.808E-2
|
2.148E-1
|
3.624E-1
|
7
|
205
|
11
|
hsa-miR-376b:PITA
|
hsa-miR-376b:PITA TOP
|
PITA
|
3.076E-4
|
2.808E-2
|
2.148E-1
|
3.624E-1
|
7
|
205
|
12
|
hsa-miR-499-3p:PITA
|
hsa-miR-499-3p:PITA TOP
|
PITA
|
3.214E-4
|
2.808E-2
|
2.148E-1
|
3.786E-1
|
9
|
345
|
13
|
miR-23a:PicTar
|
miR-23a:PicTar
|
PicTar
|
3.215E-4
|
2.808E-2
|
2.148E-1
|
3.787E-1
|
10
|
422
|
14
|
miR-23b:PicTar
|
miR-23b:PicTar
|
PicTar
|
3.337E-4
|
2.808E-2
|
2.148E-1
|
3.931E-1
|
10
|
424
|
15
|
TTTTGAG,MIR-373:MSigDB
|
TTTTGAG,MIR-373:MSigDB
|
MSigDB
|
3.767E-4
|
2.958E-2
|
2.263E-1
|
4.438E-1
|
7
|
212
|
16
|
hsa-miR-202:PITA
|
hsa-miR-202:PITA TOP
|
PITA
|
4.964E-4
|
3.303E-2
|
2.526E-1
|
5.848E-1
|
7
|
222
|
17
|
ACTGTGA,MIR-27B:MSigDB
|
ACTGTGA,MIR-27B:MSigDB
|
MSigDB
|
5.046E-4
|
3.303E-2
|
2.526E-1
|
5.945E-1
|
10
|
447
|
18
|
ACTGTGA,MIR-27A:MSigDB
|
ACTGTGA,MIR-27A:MSigDB
|
MSigDB
|
5.046E-4
|
3.303E-2
|
2.526E-1
|
5.945E-1
|
10
|
447
|
19
|
hsa-miR-146b:miRTarbase
|
hsa-miR-146b:miRTarbase
|
miRTarbase
|
5.715E-4
|
3.425E-2
|
2.619E-1
|
6.733E-1
|
2
|
6
|
20
|
miR-31:PicTar
|
miR-31:PicTar
|
PicTar
|
5.814E-4
|
3.425E-2
|
2.619E-1
|
6.849E-1
|
6
|
164
|
21
|
hsa-miR-28-3p:PITA
|
hsa-miR-28-3p:PITA TOP
|
PITA
|
6.599E-4
|
3.596E-2
|
2.751E-1
|
7.773E-1
|
6
|
168
|
22
|
hsa-miR-502-3p:PITA
|
hsa-miR-502-3p:PITA TOP
|
PITA
|
6.807E-4
|
3.596E-2
|
2.751E-1
|
8.019E-1
|
6
|
169
|
23
|
hsa-miR-501-3p:PITA
|
hsa-miR-501-3p:PITA TOP
|
PITA
|
7.021E-4
|
3.596E-2
|
2.751E-1
|
8.270E-1
|
6
|
170
|
24
|
hsa-miR-129-3p:PITA
|
hsa-miR-129-3p:PITA TOP
|
PITA
|
7.493E-4
|
3.658E-2
|
2.798E-1
|
8.827E-1
|
7
|
238
|
25
|
miR-25:PicTar
|
miR-25:PicTar
|
PicTar
|
7.763E-4
|
3.658E-2
|
2.798E-1
|
9.145E-1
|
8
|
312
|
26
|
AATGTGA,MIR-23A:MSigDB
|
AATGTGA,MIR-23A:MSigDB
|
MSigDB
|
8.644E-4
|
3.735E-2
|
2.857E-1
|
1.000E0
|
9
|
396
|
27
|
AATGTGA,MIR-23B:MSigDB
|
AATGTGA,MIR-23B:MSigDB
|
MSigDB
|
8.644E-4
|
3.735E-2
|
2.857E-1
|
1.000E0
|
9
|
396
|
28
|
miR-205:PicTar
|
miR-205:PicTar
|
PicTar
|
8.879E-4
|
3.735E-2
|
2.857E-1
|
1.000E0
|
7
|
245
|
29
|
miR-145:PicTar
|
miR-145:PicTar
|
PicTar
|
9.310E-4
|
3.782E-2
|
2.893E-1
|
1.000E0
|
7
|
247
|
30
|
miR-125b:PicTar
|
miR-125b:PicTar
|
PicTar
|
1.179E-3
|
4.631E-2
|
3.542E-1
|
1.000E0
|
9
|
414
|
31
|
miR-125a:PicTar
|
miR-125a:PicTar
|
PicTar
|
1.261E-3
|
4.790E-2
|
3.664E-1
|
1.000E0
|
9
|
418
|
32
|
miR-199a-star:PicTar
|
miR-199a-star:PicTar
|
PicTar
|
1.346E-3
|
4.956E-2
|
3.791E-1
|
1.000E0
|
9
|
422
|
Show 27 more annotations
|
17: Drug [Display Chart]
19907 annotations before applied cutoff / 22098 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
D005228
|
Fatty Acids, Essential
|
CTD
|
1.746E-21
|
3.475E-17
|
3.641E-16
|
3.475E-17
|
15
|
58
|
2
|
CID000001107
|
sterol
|
Stitch
|
1.061E-19
|
1.056E-15
|
1.106E-14
|
2.112E-15
|
22
|
265
|
3
|
C519728
|
archazolid B
|
CTD
|
1.772E-15
|
9.693E-12
|
1.015E-10
|
3.528E-11
|
12
|
65
|
4
|
1105 UP
|
monensin; Up 200; 10.9uM; MCF7; HT HG-U133A EA
|
Broad Institute CMAP
|
1.948E-15
|
9.693E-12
|
1.015E-10
|
3.877E-11
|
16
|
170
|
5
|
D005395
|
Fish Oils
|
CTD
|
3.727E-15
|
1.484E-11
|
1.554E-10
|
7.419E-11
|
15
|
145
|
6
|
CID000000856
|
tirucallol
|
Stitch
|
3.365E-14
|
1.117E-10
|
1.170E-9
|
6.700E-10
|
12
|
82
|
7
|
CID000247705
|
AC1L6KTW
|
Stitch
|
3.428E-13
|
8.890E-10
|
9.313E-9
|
6.824E-9
|
11
|
74
|
8
|
C018406
|
1-(3-trifluoromethylphenyl)piperazine
|
CTD
|
3.573E-13
|
8.890E-10
|
9.313E-9
|
7.112E-9
|
8
|
23
|
9
|
3443 UP
|
Monensin sodium salt [22373-78-0]; Up 200; 5.8uM; MCF7; HT HG-U133A
|
Broad Institute CMAP
|
6.573E-13
|
1.454E-9
|
1.523E-8
|
1.308E-8
|
14
|
168
|
10
|
CID000003962
|
Epi Lovastatin
|
Stitch
|
7.340E-13
|
1.461E-9
|
1.531E-8
|
1.461E-8
|
18
|
341
|
11
|
D005411
|
Flame Retardants
|
CTD
|
1.246E-12
|
2.256E-9
|
2.363E-8
|
2.481E-8
|
14
|
176
|
12
|
D007529
|
Isoflavones
|
CTD
|
1.454E-12
|
2.413E-9
|
2.527E-8
|
2.895E-8
|
15
|
217
|
13
|
C461488
|
N-benzylpiperazine
|
CTD
|
3.464E-12
|
5.305E-9
|
5.558E-8
|
6.897E-8
|
10
|
66
|
14
|
D002110
|
Caffeine
|
CTD
|
4.019E-12
|
5.714E-9
|
5.986E-8
|
8.000E-8
|
20
|
490
|
15
|
C078092
|
1-piperonylpiperazine
|
CTD
|
8.482E-12
|
1.055E-8
|
1.106E-7
|
1.689E-7
|
9
|
50
|
16
|
C003585
|
22-hydroxycholesterol
|
CTD
|
8.482E-12
|
1.055E-8
|
1.106E-7
|
1.689E-7
|
9
|
50
|
17
|
C002994
|
ethylene dimethanesulfonate
|
CTD
|
1.234E-11
|
1.445E-8
|
1.514E-7
|
2.456E-7
|
9
|
52
|
18
|
1276 DN
|
Dequalinium dichloride [522-51-0]; Down 200; 7.6uM; HL60; HT HG-U133A
|
Broad Institute CMAP
|
1.830E-11
|
2.023E-8
|
2.120E-7
|
3.642E-7
|
13
|
174
|
19
|
C483161
|
beta-hydroxy simvastatin acid
|
CTD
|
1.953E-11
|
2.046E-8
|
2.143E-7
|
3.888E-7
|
10
|
78
|
20
|
7178 UP
|
Tetrandrine [518-34-3]; Up 200; 6.4uM; MCF7; HT HG-U133A
|
Broad Institute CMAP
|
2.271E-11
|
2.261E-8
|
2.368E-7
|
4.521E-7
|
13
|
177
|
21
|
C016527
|
isoquercitrin
|
CTD
|
2.635E-11
|
2.498E-8
|
2.617E-7
|
5.245E-7
|
8
|
37
|
22
|
2410 UP
|
Perhexiline maleate [6724-53-4]; Up 200; 10.2uM; HL60; HT HG-U133A
|
Broad Institute CMAP
|
2.808E-11
|
2.541E-8
|
2.662E-7
|
5.589E-7
|
13
|
180
|
23
|
D015056
|
1-Methyl-3-isobutylxanthine
|
CTD
|
7.106E-11
|
6.150E-8
|
6.443E-7
|
1.415E-6
|
17
|
391
|
24
|
D008148
|
Lovastatin
|
CTD
|
8.178E-11
|
6.783E-8
|
7.106E-7
|
1.628E-6
|
13
|
196
|
25
|
CID000000449
|
m vs
|
Stitch
|
1.078E-10
|
8.587E-8
|
8.996E-7
|
2.147E-6
|
14
|
245
|
26
|
D005944
|
Glucosamine
|
CTD
|
1.927E-10
|
1.475E-7
|
1.545E-6
|
3.836E-6
|
15
|
306
|
27
|
2456 UP
|
Ciclopirox ethanolamine [41621-49-2]; Up 200; 15uM; HL60; HT HG-U133A
|
Broad Institute CMAP
|
2.876E-10
|
2.120E-7
|
2.221E-6
|
5.725E-6
|
12
|
174
|
28
|
C013698
|
tallow
|
CTD
|
3.186E-10
|
2.265E-7
|
2.373E-6
|
6.343E-6
|
14
|
266
|
29
|
CID000000317
|
CoA group
|
Stitch
|
3.431E-10
|
2.355E-7
|
2.467E-6
|
6.830E-6
|
17
|
433
|
30
|
6919 UP
|
scriptaid; Up 200; 10uM; PC3; HT HG-U133A
|
Broad Institute CMAP
|
5.482E-10
|
3.638E-7
|
3.811E-6
|
1.091E-5
|
12
|
184
|
31
|
CID000092746
|
zymosterol
|
Stitch
|
7.004E-10
|
4.498E-7
|
4.712E-6
|
1.394E-5
|
7
|
34
|
32
|
CID000000172
|
7-dehydrocholesterol
|
Stitch
|
7.636E-10
|
4.751E-7
|
4.977E-6
|
1.520E-5
|
9
|
81
|
33
|
CID000000084
|
3-hydroxy-3-methylglutaryl-CoA
|
Stitch
|
8.562E-10
|
5.165E-7
|
5.411E-6
|
1.704E-5
|
13
|
237
|
34
|
D001973
|
Bromodeoxyuridine
|
CTD
|
1.322E-9
|
7.739E-7
|
8.108E-6
|
2.631E-5
|
7
|
37
|
35
|
2651 UP
|
Suloctidil [54063-56-8]; Up 200; 11.8uM; MCF7; HT HG-U133A
|
Broad Institute CMAP
|
1.388E-9
|
7.895E-7
|
8.270E-6
|
2.763E-5
|
11
|
157
|
36
|
2227 UP
|
Terfenadine [50679-08-8]; Up 200; 8.4uM; MCF7; HT HG-U133A
|
Broad Institute CMAP
|
1.813E-9
|
1.002E-6
|
1.050E-5
|
3.609E-5
|
11
|
161
|
37
|
1486 UP
|
Thioridazine hydrochloride [130-61-0]; Up 200; 9.8uM; MCF7; HT HG-U133A
|
Broad Institute CMAP
|
1.936E-9
|
1.041E-6
|
1.091E-5
|
3.854E-5
|
11
|
162
|
38
|
1053 UP
|
prochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HT HG-U133A EA
|
Broad Institute CMAP
|
2.506E-9
|
1.313E-6
|
1.375E-5
|
4.988E-5
|
11
|
166
|
39
|
D002793
|
Cholic Acids
|
CTD
|
2.577E-9
|
1.316E-6
|
1.378E-5
|
5.131E-5
|
10
|
127
|
40
|
CID000000420
|
7 cholesterol
|
Stitch
|
2.663E-9
|
1.325E-6
|
1.388E-5
|
5.300E-5
|
8
|
64
|
41
|
C032910
|
triadimefon
|
CTD
|
2.926E-9
|
1.421E-6
|
1.488E-5
|
5.825E-5
|
15
|
373
|
42
|
D015741
|
Metribolone
|
CTD
|
3.504E-9
|
1.661E-6
|
1.740E-5
|
6.975E-5
|
15
|
378
|
43
|
D002784
|
Cholesterol
|
CTD
|
3.597E-9
|
1.665E-6
|
1.744E-5
|
7.160E-5
|
12
|
217
|
44
|
D003314
|
Corn Oil
|
CTD
|
4.914E-9
|
2.223E-6
|
2.329E-5
|
9.781E-5
|
8
|
69
|
45
|
2830 UP
|
Norcyclobenzaprine [303-50-4]; Up 200; 15.4uM; MCF7; HT HG-U133A
|
Broad Institute CMAP
|
5.539E-9
|
2.450E-6
|
2.567E-5
|
1.103E-4
|
11
|
179
|
46
|
C423915
|
TO-901317
|
CTD
|
6.075E-9
|
2.629E-6
|
2.754E-5
|
1.209E-4
|
9
|
102
|
47
|
1755 DN
|
Papaverine hydrochloride [61-25-6]; Down 200; 10.6uM; HL60; HG-U133A
|
Broad Institute CMAP
|
6.222E-9
|
2.636E-6
|
2.761E-5
|
1.239E-4
|
11
|
181
|
48
|
1365 UP
|
Astemizole [68844-77-9]; Up 200; 8.8uM; HL60; HG-U133A
|
Broad Institute CMAP
|
7.819E-9
|
3.243E-6
|
3.397E-5
|
1.557E-4
|
11
|
185
|
49
|
6807 UP
|
Astemizole [68844-77-9]; Up 200; 8.8uM; MCF7; HT HG-U133A
|
Broad Institute CMAP
|
1.469E-8
|
5.969E-6
|
6.253E-5
|
2.925E-4
|
10
|
152
|
50
|
CID000000929
|
beta-NADP
|
Stitch
|
1.614E-8
|
6.428E-6
|
6.734E-5
|
3.214E-4
|
16
|
490
|
Show 45 more annotations
|
18: Disease [Display Chart]
1573 annotations before applied cutoff / 16150 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
umls:C1517445
|
Ganglioneuroblastoma, Nodular
|
DisGeNET BeFree
|
1.437E-6
|
1.874E-3
|
1.487E-2
|
2.260E-3
|
3
|
4
|
2
|
umls:C1514225
|
Poorly Differentiated Neuroblastoma
|
DisGeNET BeFree
|
3.573E-6
|
1.874E-3
|
1.487E-2
|
5.621E-3
|
3
|
5
|
3
|
umls:C0265267
|
Congenital Hemidysplasia with Ichthyosiform Erythroderma and Limb Defects
|
DisGeNET Curated
|
3.573E-6
|
1.874E-3
|
1.487E-2
|
5.621E-3
|
3
|
5
|
4
|
umls:C0553580
|
Ewings sarcoma
|
DisGeNET Curated
|
2.472E-5
|
9.719E-3
|
7.716E-2
|
3.888E-2
|
9
|
215
|
5
|
umls:C1865596
|
Desmosterolosis
|
DisGeNET Curated
|
5.115E-5
|
1.341E-2
|
1.064E-1
|
8.046E-2
|
2
|
2
|
6
|
umls:C3151781
|
CK SYNDROME
|
DisGeNET Curated
|
5.115E-5
|
1.341E-2
|
1.064E-1
|
8.046E-2
|
2
|
2
|
7
|
umls:C0940937
|
precancerous lesions
|
DisGeNET BeFree
|
1.147E-4
|
2.402E-2
|
1.907E-1
|
1.804E-1
|
6
|
106
|
8
|
umls:C0020443
|
Hypercholesterolemia
|
DisGeNET Curated
|
1.274E-4
|
2.402E-2
|
1.907E-1
|
2.003E-1
|
7
|
155
|
9
|
umls:C1846421
|
Lathosterolosis
|
DisGeNET Curated
|
1.527E-4
|
2.402E-2
|
1.907E-1
|
2.402E-1
|
2
|
3
|
10
|
umls:C1708550
|
Intimal sarcoma
|
DisGeNET BeFree
|
1.527E-4
|
2.402E-2
|
1.907E-1
|
2.402E-1
|
2
|
3
|
11
|
umls:C0206718
|
Ganglioneuroblastoma
|
DisGeNET BeFree
|
2.512E-4
|
3.592E-2
|
2.852E-1
|
3.952E-1
|
4
|
43
|
12
|
20090112:Kathiresan
|
HDL cholesterol
|
GWAS
|
3.000E-4
|
3.679E-2
|
2.920E-1
|
4.718E-1
|
4
|
45
|
13
|
umls:C0242216
|
Biliary calculi
|
DisGeNET Curated
|
3.040E-4
|
3.679E-2
|
2.920E-1
|
4.782E-1
|
2
|
4
|
14
|
umls:C0281361
|
Adenocarcinoma of pancreas
|
DisGeNET BeFree
|
3.889E-4
|
4.302E-2
|
3.415E-1
|
6.118E-1
|
9
|
309
|
15
|
umls:C0280324
|
Laryngeal Squamous Cell Carcinoma
|
DisGeNET Curated
|
4.102E-4
|
4.302E-2
|
3.415E-1
|
6.453E-1
|
6
|
134
|
16
|
umls:C0024667
|
Animal Mammary Neoplasms
|
DisGeNET Curated
|
4.798E-4
|
4.717E-2
|
3.744E-1
|
7.547E-1
|
6
|
138
|
Show 11 more annotations
|
|