Toppgene analysis for aggregated_1964_log, IC26, positive side

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1: GO: Molecular Function [Display Chart] 598 annotations before applied cutoff / 18819 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0005539 glycosaminoglycan binding 9.328E-17 5.578E-14 3.889E-13 5.578E-14 23 219
2 GO:0019838 growth factor binding 5.351E-16 1.600E-13 1.115E-12 3.200E-13 19 142
3 GO:0005201 extracellular matrix structural constituent 6.321E-14 1.260E-11 8.785E-11 3.780E-11 14 78
4 GO:0008201 heparin binding 2.180E-11 3.259E-9 2.272E-8 1.304E-8 16 167
5 GO:1901681 sulfur compound binding 3.247E-11 3.883E-9 2.707E-8 1.942E-8 19 260
6 GO:0048407 platelet-derived growth factor binding 1.037E-9 1.034E-7 7.205E-7 6.201E-7 6 12
7 GO:0001968 fibronectin binding 1.036E-6 8.850E-5 6.170E-4 6.195E-4 6 33
8 GO:0071837 HMG box domain binding 3.364E-6 2.515E-4 1.753E-3 2.012E-3 5 23
9 GO:0005518 collagen binding 9.927E-6 6.596E-4 4.598E-3 5.936E-3 7 72
10 GO:0043394 proteoglycan binding 2.932E-5 1.693E-3 1.180E-2 1.754E-2 5 35
11 GO:0050431 transforming growth factor beta binding 3.114E-5 1.693E-3 1.180E-2 1.862E-2 4 18
12 GO:0005534 galactose binding 3.776E-5 1.882E-3 1.312E-2 2.258E-2 3 7
13 GO:0019199 transmembrane receptor protein kinase activity 4.618E-5 2.124E-3 1.481E-2 2.761E-2 7 91
14 GO:0031995 insulin-like growth factor II binding 5.995E-5 2.561E-3 1.785E-2 3.585E-2 3 8
15 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding 1.079E-4 4.303E-3 3.000E-2
6.454E-2
 2 2
16 GO:0005044 scavenger receptor activity 1.252E-4 4.450E-3 3.102E-2
7.488E-2
 5 47
17 GO:0005024 transforming growth factor beta-activated receptor activity 1.265E-4 4.450E-3 3.102E-2
7.565E-2
 3 10
18 GO:0005520 insulin-like growth factor binding 1.921E-4 6.381E-3 4.449E-2
1.149E-1
 4 28
19 GO:0031994 insulin-like growth factor I binding 2.284E-4 7.188E-3
5.011E-2
1.366E-1
 3 12
20 GO:0001948 glycoprotein binding 2.634E-4 7.876E-3
5.491E-2
1.575E-1
 7 120
21 GO:0005178 integrin binding 2.915E-4 8.012E-3
5.586E-2
1.743E-1
 7 122
22 GO:0050840 extracellular matrix binding 3.142E-4 8.012E-3
5.586E-2
1.879E-1
 5 57
23 GO:0035373 chondroitin sulfate proteoglycan binding 3.215E-4 8.012E-3
5.586E-2
1.923E-1
 2 3
24 GO:0004096 catalase activity 3.215E-4 8.012E-3
5.586E-2
1.923E-1
 2 3
25 GO:0050839 cell adhesion molecule binding 3.532E-4 8.449E-3
5.890E-2
2.112E-1
 9 209
26 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding 3.991E-4 9.179E-3
6.399E-2
2.387E-1
 10 259
27 GO:0019955 cytokine binding 7.318E-4 1.621E-2
1.130E-1
4.376E-1
 6 103
28 GO:0038024 cargo receptor activity 8.688E-4 1.822E-2
1.270E-1
5.196E-1
 5 71
29 GO:0004857 enzyme inhibitor activity 8.836E-4 1.822E-2
1.270E-1
5.284E-1
 12 393
30 GO:0038085 vascular endothelial growth factor binding 1.057E-3 2.107E-2
1.469E-1
6.322E-1
 2 5
31 GO:0004222 metalloendopeptidase activity 1.187E-3 2.290E-2
1.596E-1
7.098E-1
 6 113
32 GO:0046332 SMAD binding 1.254E-3 2.343E-2
1.634E-1
7.498E-1
 5 77
33 GO:0048029 monosaccharide binding 1.488E-3 2.696E-2
1.880E-1
8.897E-1
 5 80
34 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1.916E-3 3.371E-2
2.350E-1
1.000E0
 3 24
35 GO:0004866 endopeptidase inhibitor activity 2.129E-3 3.638E-2
2.536E-1
1.000E0
 7 171
36 GO:0061134 peptidase regulator activity 2.392E-3 3.973E-2
2.770E-1
1.000E0
 8 223
37 GO:0061135 endopeptidase regulator activity 2.584E-3 4.177E-2
2.912E-1
1.000E0
 7 177
38 GO:0030414 peptidase inhibitor activity 2.838E-3 4.467E-2
3.114E-1
1.000E0
 7 180
39 GO:0004175 endopeptidase activity 3.114E-3 4.774E-2
3.328E-1
1.000E0
 12 457
40 GO:0004867 serine-type endopeptidase inhibitor activity 3.310E-3 4.920E-2
3.430E-1
1.000E0
 5 96
41 GO:0030246 carbohydrate binding 3.454E-3 4.920E-2
3.430E-1
1.000E0
 9 290
42 GO:0008237 metallopeptidase activity 3.609E-3 4.920E-2
3.430E-1
1.000E0
 7 188
43 GO:0043208 glycosphingolipid binding 3.703E-3 4.920E-2
3.430E-1
1.000E0
 2 9
44 GO:0032052 bile acid binding 3.703E-3 4.920E-2
3.430E-1
1.000E0
 2 9
45 GO:0052650 NADP-retinol dehydrogenase activity 3.703E-3 4.920E-2
3.430E-1
1.000E0
 2 9
Show 40 more annotations

2: GO: Biological Process [Display Chart] 3413 annotations before applied cutoff / 18785 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0030198 extracellular matrix organization 1.006E-28 1.913E-25 1.667E-24 3.434E-25 39 354
2 GO:0043062 extracellular structure organization 1.121E-28 1.913E-25 1.667E-24 3.826E-25 39 355
3 GO:0001503 ossification 1.372E-13 1.561E-10 1.360E-9 4.682E-10 26 406
4 GO:0022617 extracellular matrix disassembly 1.264E-11 1.079E-8 9.398E-8 4.315E-8 13 92
5 GO:0030574 collagen catabolic process 9.298E-11 6.347E-8 5.530E-7 3.173E-7 11 67
6 GO:0048706 embryonic skeletal system development 1.751E-10 9.961E-8 8.679E-7 5.977E-7 14 137
7 GO:0044243 multicellular organismal catabolic process 2.838E-10 1.384E-7 1.206E-6 9.688E-7 11 74
8 GO:0048705 skeletal system morphogenesis 4.442E-10 1.795E-7 1.564E-6 1.516E-6 17 235
9 GO:0032963 collagen metabolic process 4.734E-10 1.795E-7 1.564E-6 1.616E-6 13 122
10 GO:0035987 endodermal cell differentiation 7.812E-10 2.431E-7 2.118E-6 2.666E-6 9 45
11 GO:0044259 multicellular organismal macromolecule metabolic process 7.834E-10 2.431E-7 2.118E-6 2.674E-6 13 127
12 GO:0050673 epithelial cell proliferation 1.034E-9 2.940E-7 2.562E-6 3.528E-6 21 394
13 GO:0007492 endoderm development 2.444E-9 6.416E-7 5.590E-6 8.341E-6 11 90
14 GO:0044236 multicellular organism metabolic process 4.041E-9 9.852E-7 8.584E-6 1.379E-5 13 145
15 GO:0001706 endoderm formation 6.050E-9 1.377E-6 1.199E-5 2.065E-5 9 56
16 GO:0031589 cell-substrate adhesion 9.054E-9 1.931E-6 1.683E-5 3.090E-5 18 324
17 GO:0048562 embryonic organ morphogenesis 1.045E-8 2.097E-6 1.827E-5 3.566E-5 18 327
18 GO:0048704 embryonic skeletal system morphogenesis 1.154E-8 2.188E-6 1.907E-5 3.939E-5 11 104
19 GO:0001101 response to acid chemical 1.346E-8 2.379E-6 2.073E-5 4.594E-5 19 372
20 GO:0001649 osteoblast differentiation 1.394E-8 2.379E-6 2.073E-5 4.758E-5 15 224
21 GO:0071560 cellular response to transforming growth factor beta stimulus 2.106E-8 3.423E-6 2.983E-5 7.189E-5 15 231
22 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 2.495E-8 3.871E-6 3.373E-5 8.516E-5 18 346
23 GO:0071559 response to transforming growth factor beta 2.649E-8 3.931E-6 3.425E-5 9.041E-5 15 235
24 GO:0090287 regulation of cellular response to growth factor stimulus 8.208E-8 1.167E-5 1.017E-4 2.801E-4 15 256
25 GO:0001525 angiogenesis 9.459E-8 1.291E-5 1.125E-4 3.228E-4 20 465
26 GO:0060348 bone development 1.396E-7 1.832E-5 1.597E-4 4.764E-4 13 195
27 GO:0051216 cartilage development 1.667E-7 2.087E-5 1.818E-4 5.690E-4 13 198
28 GO:0060324 face development 1.712E-7 2.087E-5 1.818E-4 5.844E-4 8 59
29 GO:1904888 cranial skeletal system development 2.542E-7 2.991E-5 2.606E-4 8.675E-4 8 62
30 GO:0071229 cellular response to acid chemical 2.636E-7 2.999E-5 2.613E-4 8.997E-4 13 206
31 GO:0030199 collagen fibril organization 3.343E-7 3.610E-5 3.146E-4 1.141E-3 7 44
32 GO:0050678 regulation of epithelial cell proliferation 3.385E-7 3.610E-5 3.146E-4 1.155E-3 16 326
33 GO:0071230 cellular response to amino acid stimulus 3.694E-7 3.821E-5 3.329E-4 1.261E-3 8 65
34 GO:1903224 regulation of endodermal cell differentiation 3.926E-7 3.940E-5 3.433E-4 1.340E-3 4 7
35 GO:0035239 tube morphogenesis 4.069E-7 3.940E-5 3.433E-4 1.389E-3 18 417
36 GO:0060021 palate development 4.156E-7 3.940E-5 3.433E-4 1.419E-3 9 90
37 GO:0001822 kidney development 4.685E-7 4.322E-5 3.765E-4 1.599E-3 15 293
38 GO:0048771 tissue remodeling 5.109E-7 4.588E-5 3.998E-4 1.744E-3 12 183
39 GO:0048645 animal organ formation 5.906E-7 5.153E-5 4.490E-4 2.016E-3 8 69
40 GO:0060349 bone morphogenesis 6.039E-7 5.153E-5 4.490E-4 2.061E-3 9 94
41 GO:0061138 morphogenesis of a branching epithelium 6.201E-7 5.162E-5 4.498E-4 2.116E-3 13 222
42 GO:0040017 positive regulation of locomotion 6.687E-7 5.434E-5 4.735E-4 2.282E-3 19 478
43 GO:0048568 embryonic organ development 7.817E-7 6.204E-5 5.406E-4 2.668E-3 19 483
44 GO:0061448 connective tissue development 8.994E-7 6.977E-5 6.079E-4 3.070E-3 14 268
45 GO:0048701 embryonic cranial skeleton morphogenesis 9.495E-7 7.201E-5 6.274E-4 3.241E-3 7 51
46 GO:0072001 renal system development 9.937E-7 7.373E-5 6.424E-4 3.392E-3 15 311
47 GO:0043200 response to amino acid 1.019E-6 7.400E-5 6.448E-4 3.478E-3 10 129
48 GO:0030335 positive regulation of cell migration 1.074E-6 7.639E-5 6.656E-4 3.667E-3 18 446
49 GO:0001655 urogenital system development 1.171E-6 8.154E-5 7.104E-4 3.995E-3 16 358
50 GO:0001763 morphogenesis of a branching structure 1.358E-6 9.270E-5 8.076E-4 4.635E-3 13 238
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 278 annotations before applied cutoff / 19172 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0031012 extracellular matrix 1.691E-29 4.702E-27 2.919E-26 4.702E-27 43 444
2 GO:0005578 proteinaceous extracellular matrix 1.298E-26 1.805E-24 1.120E-23 3.609E-24 38 379
3 GO:0044420 extracellular matrix component 2.016E-22 1.869E-20 1.160E-19 5.606E-20 24 143
4 GO:0098644 complex of collagen trimers 8.032E-13 5.582E-11 3.465E-10 2.233E-10 9 23
5 GO:0005604 basement membrane 8.649E-12 4.809E-10 2.985E-9 2.404E-9 14 111
6 GO:0005581 collagen trimer 1.090E-10 5.049E-9 3.134E-8 3.030E-8 12 88
7 GO:0005583 fibrillar collagen trimer 9.870E-10 3.430E-8 2.129E-7 2.744E-7 6 12
8 GO:0098643 banded collagen fibril 9.870E-10 3.430E-8 2.129E-7 2.744E-7 6 12
9 GO:0005589 collagen type VI trimer 1.085E-6 3.016E-5 1.872E-4 3.016E-4 3 3
10 GO:0098647 collagen beaded filament 1.085E-6 3.016E-5 1.872E-4 3.016E-4 3 3
11 GO:0005788 endoplasmic reticulum lumen 6.037E-5 1.526E-3 9.470E-3 1.678E-2 10 207
12 GO:0005584 collagen type I trimer 1.061E-4 2.459E-3 1.526E-2 2.950E-2 2 2
13 GO:0031091 platelet alpha granule 1.253E-4 2.679E-3 1.663E-2 3.483E-2 6 75
14 GO:0031093 platelet alpha granule lumen 2.556E-4 4.884E-3 3.031E-2
7.104E-2
 5 55
15 GO:0043202 lysosomal lumen 3.018E-4 4.884E-3 3.031E-2
8.391E-2
 6 88
16 GO:0005606 laminin-1 complex 3.162E-4 4.884E-3 3.031E-2
8.791E-2
 2 3
17 GO:0005588 collagen type V trimer 3.162E-4 4.884E-3 3.031E-2
8.791E-2
 2 3
18 GO:0043259 laminin-10 complex 3.162E-4 4.884E-3 3.031E-2
8.791E-2
 2 3
19 GO:0070022 transforming growth factor beta receptor complex 6.281E-4 9.190E-3
5.704E-2
1.746E-1
 2 4
20 GO:0031983 vesicle lumen 8.990E-4 1.250E-2
7.756E-2
2.499E-1
 6 108
21 GO:0005775 vacuolar lumen 1.303E-3 1.724E-2
1.070E-1
3.621E-1
 6 116
22 GO:0005605 basal lamina 1.650E-3 2.085E-2
1.294E-1
4.587E-1
 3 23
23 GO:0034774 secretory granule lumen 1.878E-3 2.270E-2
1.409E-1
5.221E-1
 5 85
24 GO:0043256 laminin complex 2.852E-3 3.304E-2
2.051E-1
7.929E-1
 2 8
25 GO:0005796 Golgi lumen 3.195E-3 3.553E-2
2.205E-1
8.882E-1
 5 96
26 GO:0072562 blood microparticle 3.731E-3 3.989E-2
2.476E-1
1.000E0
 6 143
27 GO:0060205 cytoplasmic vesicle lumen 4.500E-3 4.490E-2
2.787E-1
1.000E0
 5 104
28 GO:0001527 microfibril 4.522E-3 4.490E-2
2.787E-1
1.000E0
 2 10
29 GO:0042383 sarcolemma 5.181E-3 4.967E-2
3.083E-1
1.000E0
 6 153
Show 24 more annotations

4: Human Phenotype [Display Chart] 951 annotations before applied cutoff / 4410 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0001388 Joint laxity 2.223E-8 1.389E-5 1.033E-4 2.114E-5 12 95
2 HP:0000977 Soft skin {has synonym type="layperson"} 2.922E-8 1.389E-5 1.033E-4 2.779E-5 7 22
3 HP:0001058 Poor wound healing {has synonym type="layperson"} 5.063E-8 1.605E-5 1.193E-4 4.815E-5 5 8
4 HP:0001073 Cigarette-paper scars {has synonym type="layperson"} 3.049E-7 5.989E-5 4.453E-4 2.900E-4 4 5
5 HP:0000974 Hyperextensible skin 3.149E-7 5.989E-5 4.453E-4 2.994E-4 7 30
6 HP:0000592 Blue sclerae 4.049E-7 6.418E-5 4.772E-4 3.851E-4 8 45
7 HP:0000993 Molluscoid pseudotumors 9.037E-7 1.228E-4 9.128E-4 8.594E-4 4 6
8 HP:0000978 Bruising susceptibility {has synonym type="layperson"} 1.642E-6 1.952E-4 1.452E-3 1.562E-3 9 72
9 HP:0002010 Narrow maxilla 4.001E-6 3.345E-4 2.487E-3 3.805E-3 3 3
10 HP:0005100 Premature birth following premature rupture of fetal membranes 4.001E-6 3.345E-4 2.487E-3 3.805E-3 3 3
11 HP:0005222 Bowel diverticulosis 4.001E-6 3.345E-4 2.487E-3 3.805E-3 3 3
12 HP:0001634 Mitral valve prolapse 4.220E-6 3.345E-4 2.487E-3 4.013E-3 7 43
13 HP:0000023 Inguinal hernia 5.852E-6 4.281E-4 3.183E-3 5.566E-3 11 131
14 HP:0001763 Pes planus 9.864E-6 6.700E-4 4.982E-3 9.380E-3 9 89
15 HP:0006316 Irregularly spaced teeth {has synonym type="layperson"} 1.582E-5 9.403E-4 6.991E-3 1.504E-2 3 4
16 HP:0005758 Basilar impression 1.582E-5 9.403E-4 6.991E-3 1.504E-2 3 4
17 HP:0002758 Osteoarthritis 1.997E-5 1.117E-3 8.308E-3 1.900E-2 5 22
18 HP:0001156 Brachydactyly syndrome 3.310E-5 1.749E-3 1.300E-2 3.148E-2 11 157
19 HP:0003304 Spondylolysis 3.909E-5 1.957E-3 1.455E-2 3.718E-2 3 5
20 HP:0001373 Joint dislocation {has synonym type="layperson"} 5.469E-5 2.601E-3 1.934E-2
5.201E-2
 4 14
21 HP:0000394 Lop ear 7.728E-5 3.379E-3 2.512E-2
7.349E-2
 3 6
22 HP:0000939 Osteoporosis 7.817E-5 3.379E-3 2.512E-2
7.434E-2
 9 115
23 HP:0002645 Wormian bones 8.252E-5 3.412E-3 2.537E-2
7.847E-2
 5 29
24 HP:0011001 Increased bone mineral density {has synonym type="layperson"} 1.254E-4 4.967E-3 3.693E-2
1.192E-1
 4 17
25 HP:0002644 Abnormality of pelvic girdle bone morphology 1.816E-4 6.909E-3
5.137E-2
1.727E-1
 5 34
26 HP:0006480 Premature loss of teeth 1.992E-4 7.288E-3
5.419E-2
1.895E-1
 4 19
27 HP:0005897 Severe generalized osteoporosis 2.556E-4 7.596E-3
5.648E-2
2.431E-1
 2 2
28 HP:0006086 Thin metacarpal cortices 2.556E-4 7.596E-3
5.648E-2
2.431E-1
 2 2
29 HP:0005623 Absent ossification of calvaria 2.556E-4 7.596E-3
5.648E-2
2.431E-1
 2 2
30 HP:0005005 Femoral bowing present at birth, straightening with time 2.556E-4 7.596E-3
5.648E-2
2.431E-1
 2 2
31 HP:0008780 Congenital bilateral hip dislocation 2.556E-4 7.596E-3
5.648E-2
2.431E-1
 2 2
32 HP:0003321 Biconcave flattened vertebrae 2.556E-4 7.596E-3
5.648E-2
2.431E-1
 2 2
33 HP:0003077 Hyperlipidemia 3.003E-4 8.653E-3
6.434E-2
2.855E-1
 4 21
34 HP:0003179 Protrusio acetabuli 3.135E-4 8.768E-3
6.519E-2
2.981E-1
 3 9
35 HP:0001083 Ectopia lentis 3.625E-4 9.577E-3
7.121E-2
3.448E-1
 4 22
36 HP:0001030 Fragile skin {has synonym type="layperson"} 3.625E-4 9.577E-3
7.121E-2
3.448E-1
 4 22
37 HP:0002688 Absent frontal sinuses 4.426E-4 1.108E-2
8.236E-2
4.209E-1
 3 10
38 HP:0002616 Aortic root dilatation 4.426E-4 1.108E-2
8.236E-2
4.209E-1
 3 10
39 HP:0000765 Abnormality of the thorax 5.140E-4 1.253E-2
9.319E-2
4.888E-1
 4 24
40 HP:0004349 Reduced bone mineral density 7.588E-4 1.503E-2
1.118E-1
7.216E-1
 2 3
41 HP:0006460 Increased laxity of ankles 7.588E-4 1.503E-2
1.118E-1
7.216E-1
 2 3
42 HP:0003023 Bowing of limbs due to multiple fractures 7.588E-4 1.503E-2
1.118E-1
7.216E-1
 2 3
43 HP:0000923 Beaded ribs 7.588E-4 1.503E-2
1.118E-1
7.216E-1
 2 3
44 HP:0006367 Crumpled long bones {has synonym type="layperson"} 7.588E-4 1.503E-2
1.118E-1
7.216E-1
 2 3
45 HP:0008007 Primary congenital glaucoma 7.588E-4 1.503E-2
1.118E-1
7.216E-1
 2 3
46 HP:0005072 Hyperextensibility at wrists 7.588E-4 1.503E-2
1.118E-1
7.216E-1
 2 3
47 HP:0006149 Increased laxity of fingers 7.588E-4 1.503E-2
1.118E-1
7.216E-1
 2 3
48 HP:0004474 Persistent open anterior fontanelle 7.588E-4 1.503E-2
1.118E-1
7.216E-1
 2 3
49 HP:0004586 Biconcave vertebral bodies 7.929E-4 1.508E-2
1.121E-1
7.541E-1
 3 12
50 HP:0000925 Abnormality of the vertebral column {has synonym type="layperson"} 7.929E-4 1.508E-2
1.121E-1
7.541E-1
 3 12
Show 45 more annotations

5: Mouse Phenotype [Display Chart] 3461 annotations before applied cutoff / 9299 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0000163 abnormal cartilage morphology 1.307E-13 4.524E-10 3.948E-9 4.524E-10 31 381
2 MP:0000130 abnormal trabecular bone morphology 8.533E-12 1.477E-8 1.289E-7 2.953E-8 25 286
3 MP:0008271 abnormal bone ossification 1.595E-11 1.841E-8 1.606E-7 5.522E-8 30 428
4 MP:0002113 abnormal skeleton development 2.427E-11 2.100E-8 1.833E-7 8.401E-8 32 494
5 MP:0002115 abnormal limb bone morphology 4.125E-11 2.855E-8 2.492E-7 1.428E-7 31 474
6 MP:0011504 abnormal limb long bone morphology 6.238E-11 3.599E-8 3.140E-7 2.159E-7 30 452
7 MP:0000454 abnormal jaw morphology 2.236E-10 1.105E-7 9.647E-7 7.738E-7 29 446
8 MP:0003797 abnormal compact bone morphology 4.434E-10 1.918E-7 1.674E-6 1.535E-6 18 171
9 MP:0005503 abnormal tendon morphology 5.536E-10 2.129E-7 1.858E-6 1.916E-6 10 39
10 MP:0004686 decreased length of long bones 1.124E-9 3.890E-7 3.395E-6 3.890E-6 24 331
11 MP:0000556 abnormal hindlimb morphology 4.336E-9 1.185E-6 1.034E-5 1.501E-5 26 413
12 MP:0008438 abnormal cutaneous collagen fibril morphology 4.451E-9 1.185E-6 1.034E-5 1.540E-5 8 25
13 MP:0003089 decreased skin tensile strength 4.451E-9 1.185E-6 1.034E-5 1.540E-5 8 25
14 MP:0000458 abnormal mandible morphology 8.350E-9 2.064E-6 1.801E-5 2.890E-5 18 205
15 MP:0005275 abnormal skin tensile strength 1.668E-8 3.850E-6 3.359E-5 5.774E-5 8 29
16 MP:0010876 decreased bone volume 2.884E-8 6.238E-6 5.444E-5 9.981E-5 12 90
17 MP:0002932 abnormal joint morphology 4.489E-8 8.406E-6 7.335E-5 1.554E-4 21 310
18 MP:0000074 abnormal neurocranium morphology 4.605E-8 8.406E-6 7.335E-5 1.594E-4 19 255
19 MP:0005197 abnormal uvea morphology 4.614E-8 8.406E-6 7.335E-5 1.597E-4 16 179
20 MP:0010874 abnormal bone volume 5.569E-8 9.637E-6 8.410E-5 1.927E-4 15 158
21 MP:0003935 abnormal craniofacial development 8.178E-8 1.348E-5 1.176E-4 2.831E-4 23 381
22 MP:0002989 small kidney 9.676E-8 1.522E-5 1.328E-4 3.349E-4 18 240
23 MP:0002100 abnormal tooth morphology 1.121E-7 1.688E-5 1.473E-4 3.881E-4 17 216
24 MP:0010869 decreased bone trabecula number 1.246E-7 1.797E-5 1.568E-4 4.313E-4 10 66
25 MP:0009888 palatal shelves fail to meet at midline 1.392E-7 1.927E-5 1.682E-4 4.818E-4 9 51
26 MP:0005306 abnormal phalanx morphology 1.946E-7 2.590E-5 2.260E-4 6.734E-4 11 87
27 MP:0000550 abnormal forelimb morphology 3.249E-7 4.102E-5 3.580E-4 1.125E-3 16 206
28 MP:0009887 abnormal palatal shelf fusion at midline 3.319E-7 4.102E-5 3.580E-4 1.149E-3 10 73
29 MP:0020040 decreased bone ossification 3.813E-7 4.551E-5 3.972E-4 1.320E-3 8 42
30 MP:0000455 abnormal maxilla morphology 4.694E-7 5.416E-5 4.726E-4 1.625E-3 14 161
31 MP:0006395 abnormal epiphyseal plate morphology 6.575E-7 7.340E-5 6.406E-4 2.276E-3 16 217
32 MP:0003855 abnormal forelimb zeugopod morphology 7.881E-7 8.523E-5 7.438E-4 2.727E-3 12 121
33 MP:0010029 abnormal basicranium morphology 1.004E-6 1.053E-4 9.191E-4 3.475E-3 10 82
34 MP:0003055 abnormal long bone epiphyseal plate morphology 1.064E-6 1.083E-4 9.454E-4 3.683E-3 15 198
35 MP:0004540 small maxilla 1.556E-6 1.539E-4 1.343E-3 5.386E-3 9 67
36 MP:0005006 abnormal osteoblast physiology 2.005E-6 1.927E-4 1.682E-3 6.938E-3 9 69
37 MP:0006429 abnormal hyaline cartilage morphology 2.123E-6 1.986E-4 1.733E-3 7.347E-3 6 24
38 MP:0002191 abnormal artery morphology 2.217E-6 2.019E-4 1.762E-3 7.672E-3 24 494
39 MP:0011655 abnormal systemic artery morphology 2.359E-6 2.094E-4 1.827E-3 8.166E-3 17 268
40 MP:0003098 decreased tendon stiffness 2.565E-6 2.217E-4 1.935E-3 8.878E-3 4 7
41 MP:0013545 cleft hard palate 2.651E-6 2.217E-4 1.935E-3 9.176E-3 10 91
42 MP:0000547 short limbs 2.751E-6 2.217E-4 1.935E-3 9.521E-3 12 136
43 MP:0003560 osteoarthritis 2.754E-6 2.217E-4 1.935E-3 9.533E-3 6 25
44 MP:0000088 short mandible 2.932E-6 2.306E-4 2.013E-3 1.015E-2 10 92
45 MP:0000063 decreased bone mineral density 3.758E-6 2.890E-4 2.522E-3 1.301E-2 18 308
46 MP:0000552 abnormal radius morphology 3.936E-6 2.961E-4 2.584E-3 1.362E-2 10 95
47 MP:0009655 abnormal secondary palate development 4.255E-6 3.121E-4 2.724E-3 1.473E-2 11 118
48 MP:0004592 small mandible 4.328E-6 3.121E-4 2.724E-3 1.498E-2 12 142
49 MP:0002706 abnormal kidney size 4.542E-6 3.208E-4 2.800E-3 1.572E-2 19 344
50 MP:0003097 abnormal tendon stiffness 5.063E-6 3.505E-4 3.059E-3 1.752E-2 4 8
Show 45 more annotations

6: Domain [Display Chart] 1318 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PS01186 EGF 2 PROSITE 4.124E-10 3.254E-7 2.525E-6 5.435E-7 18 266
2 SM00181 EGF SMART 4.938E-10 3.254E-7 2.525E-6 6.508E-7 17 236
3 IPR009030 Growth fac rcpt InterPro 1.023E-9 3.946E-7 3.062E-6 1.349E-6 14 156
4 IPR000742 EGF-like dom InterPro 1.197E-9 3.946E-7 3.062E-6 1.578E-6 17 250
5 IPR013032 EGF-like CS InterPro 2.445E-9 6.444E-7 5.002E-6 3.222E-6 17 262
6 PS00022 EGF 1 PROSITE 1.251E-8 2.748E-6 2.133E-5 1.649E-5 16 256
7 IPR008160 Collagen InterPro 1.977E-8 3.247E-6 2.520E-5 2.606E-5 10 85
8 PF01391 Collagen Pfam 1.977E-8 3.247E-6 2.520E-5 2.606E-5 10 85
9 PF07645 EGF CA Pfam 2.217E-8 3.247E-6 2.520E-5 2.922E-5 10 86
10 PD002078 Fib collagen C ProDom 5.228E-8 4.922E-6 3.820E-5 6.890E-5 5 11
11 PS51461 NC1 FIB PROSITE 5.228E-8 4.922E-6 3.820E-5 6.890E-5 5 11
12 IPR000885 Fib collagen C InterPro 5.228E-8 4.922E-6 3.820E-5 6.890E-5 5 11
13 PF01410 COLFI Pfam 5.228E-8 4.922E-6 3.820E-5 6.890E-5 5 11
14 SM00038 COLFI SMART 5.228E-8 4.922E-6 3.820E-5 6.890E-5 5 11
15 SM00179 EGF CA SMART 6.335E-8 5.567E-6 4.321E-5 8.350E-5 11 122
16 IPR001881 EGF-like Ca-bd dom InterPro 7.498E-8 6.176E-6 4.794E-5 9.882E-5 11 124
17 PF00008 EGF Pfam 8.845E-8 6.858E-6 5.323E-5 1.166E-4 11 126
18 PS00010 ASX HYDROXYL PROSITE 9.548E-8 6.992E-6 5.426E-5 1.258E-4 10 100
19 IPR000152 EGF-type Asp/Asn hydroxyl site InterPro 1.664E-7 1.154E-5 8.960E-5 2.193E-4 10 106
20 IPR018097 EGF Ca-bd CS InterPro 8.074E-7 5.320E-5 4.129E-4 1.064E-3 9 97
21 PS01187 EGF CA PROSITE 9.605E-7 6.028E-5 4.679E-4 1.266E-3 9 99
22 PS50026 EGF 3 PROSITE 1.272E-6 7.622E-5 5.916E-4 1.677E-3 13 236
23 PF12662 cEGF Pfam 6.551E-6 3.598E-4 2.792E-3 8.635E-3 5 26
24 IPR026823 cEGF InterPro 6.551E-6 3.598E-4 2.792E-3 8.635E-3 5 26
25 IPR009168 IGFBP1-6 InterPro 2.204E-5 1.024E-3 7.944E-3 2.904E-2 3 6
26 IPR022321 IGFBP 1-6 chordata InterPro 2.204E-5 1.024E-3 7.944E-3 2.904E-2 3 6
27 IPR000716 Thyroglobulin 1 InterPro 2.485E-5 1.024E-3 7.944E-3 3.275E-2 4 17
28 SM00211 TY SMART 2.485E-5 1.024E-3 7.944E-3 3.275E-2 4 17
29 PF00086 Thyroglobulin 1 Pfam 2.485E-5 1.024E-3 7.944E-3 3.275E-2 4 17
30 4.10.800.10 - Gene3D 2.485E-5 1.024E-3 7.944E-3 3.275E-2 4 17
31 PS00484 THYROGLOBULIN 1 1 PROSITE 2.485E-5 1.024E-3 7.944E-3 3.275E-2 4 17
32 PS51162 THYROGLOBULIN 1 2 PROSITE 2.485E-5 1.024E-3 7.944E-3 3.275E-2 4 17
33 SM00121 IB SMART 3.169E-5 1.266E-3 9.824E-3 4.177E-2 4 18
34 PS01208 VWFC 1 PROSITE 3.449E-5 1.337E-3 1.038E-2 4.546E-2 5 36
35 PS50184 VWFC 2 PROSITE 4.515E-5 1.700E-3 1.320E-2
5.951E-2
 5 38
36 PF00219 IGFBP Pfam 4.936E-5 1.712E-3 1.329E-2
6.506E-2
 4 20
37 PS51323 IGFBP N 2 PROSITE 4.936E-5 1.712E-3 1.329E-2
6.506E-2
 4 20
38 IPR000867 IGFBP-like InterPro 4.936E-5 1.712E-3 1.329E-2
6.506E-2
 4 20
39 IPR001007 VWF dom InterPro 7.397E-5 2.500E-3 1.940E-2
9.749E-2
 5 42
40 IPR020092 PTN MK heparin-bd GF CS InterPro 1.089E-4 2.760E-3 2.142E-2
1.435E-1
 2 2
41 2.30.90.10 - Gene3D 1.089E-4 2.760E-3 2.142E-2
1.435E-1
 2 2
42 IPR020091 PTN/MK diS InterPro 1.089E-4 2.760E-3 2.142E-2
1.435E-1
 2 2
43 SM00193 PTN SMART 1.089E-4 2.760E-3 2.142E-2
1.435E-1
 2 2
44 IPR020090 PTN/MK C dom InterPro 1.089E-4 2.760E-3 2.142E-2
1.435E-1
 2 2
45 PS00619 PTN MK 1 PROSITE 1.089E-4 2.760E-3 2.142E-2
1.435E-1
 2 2
46 IPR000762 Midkine heparin-bd GF InterPro 1.089E-4 2.760E-3 2.142E-2
1.435E-1
 2 2
47 PS00620 PTN MK 2 PROSITE 1.089E-4 2.760E-3 2.142E-2
1.435E-1
 2 2
48 PF05196 PTN MK N Pfam 1.089E-4 2.760E-3 2.142E-2
1.435E-1
 2 2
49 2.20.60.10 - Gene3D 1.089E-4 2.760E-3 2.142E-2
1.435E-1
 2 2
50 IPR020089 PTN/MK N dom InterPro 1.089E-4 2.760E-3 2.142E-2
1.435E-1
 2 2
Show 45 more annotations

7: Pathway [Display Chart] 915 annotations before applied cutoff / 10916 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M5884 Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans MSigDB C2 BIOCARTA (v5.1) 2.404E-24 2.200E-21 1.627E-20 2.200E-21 35 275
2 576262 Extracellular matrix organization BioSystems: REACTOME 1.343E-21 6.146E-19 4.546E-18 1.229E-18 32 264
3 M3008 Genes encoding structural ECM glycoproteins MSigDB C2 BIOCARTA (v5.1) 2.469E-14 7.529E-12 5.569E-11 2.259E-11 22 196
4 83068 ECM-receptor interaction BioSystems: KEGG 1.475E-10 3.374E-8 2.496E-7 1.350E-7 13 86
5 833812 ECM proteoglycans BioSystems: REACTOME 3.265E-9 5.974E-7 4.419E-6 2.987E-6 10 55
6 83067 Focal adhesion BioSystems: KEGG 2.356E-8 3.592E-6 2.657E-5 2.155E-5 16 206
7 730306 Assembly of collagen fibrils and other multimeric structures BioSystems: REACTOME 4.568E-8 5.971E-6 4.416E-5 4.180E-5 9 54
8 P00034 Integrin signalling pathway PantherDB 7.164E-8 8.194E-6 6.061E-5 6.555E-5 14 167
9 576263 Degradation of the extracellular matrix BioSystems: REACTOME 3.799E-7 3.862E-5 2.857E-4 3.476E-4 10 89
10 M5887 Genes encoding structural components of basement membranes MSigDB C2 BIOCARTA (v5.1) 1.072E-6 9.810E-5 7.257E-4 9.810E-4 7 40
11 198795 Focal Adhesion BioSystems: WikiPathways 1.530E-6 1.273E-4 9.415E-4 1.400E-3 13 184
12 M3005 Genes encoding collagen proteins MSigDB C2 BIOCARTA (v5.1) 2.104E-6 1.604E-4 1.187E-3 1.925E-3 7 44
13 645289 Collagen biosynthesis and modifying enzymes BioSystems: REACTOME 2.884E-6 1.954E-4 1.445E-3 2.639E-3 8 65
14 645288 Collagen formation BioSystems: REACTOME 2.989E-6 1.954E-4 1.445E-3 2.735E-3 9 87
15 198812 Endochondral Ossification BioSystems: WikiPathways 3.244E-6 1.979E-4 1.464E-3 2.968E-3 8 66
16 M3468 Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix MSigDB C2 BIOCARTA (v5.1) 5.221E-6 2.986E-4 2.209E-3 4.778E-3 14 238
17 692234 PI3K-Akt signaling pathway BioSystems: KEGG 5.667E-6 3.050E-4 2.256E-3 5.185E-3 17 346
18 M5882 Genes encoding proteoglycans MSigDB C2 BIOCARTA (v5.1) 7.393E-6 3.758E-4 2.780E-3 6.764E-3 6 35
19 645310 Dermatan sulfate biosynthesis BioSystems: REACTOME 1.077E-5 5.185E-4 3.835E-3 9.852E-3 4 11
20 730310 Elastic fibre formation BioSystems: REACTOME 1.913E-5 8.750E-4 6.472E-3 1.750E-2 6 41
21 730311 Molecules associated with elastic fibres BioSystems: REACTOME 5.109E-5 2.226E-3 1.647E-2 4.675E-2 5 30
22 198766 Inflammatory Response Pathway BioSystems: WikiPathways 7.061E-5 2.937E-3 2.172E-2
6.461E-2
 5 32
23 833814 Scavenging by Class A Receptors BioSystems: REACTOME 1.160E-4 4.615E-3 3.414E-2
1.061E-1
 4 19
24 167324 Amoebiasis BioSystems: KEGG 1.300E-4 4.957E-3 3.667E-2
1.190E-1
 8 109
25 105908 Regulation of Insulin-like Growth Factor (IGF) Transport and Uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) BioSystems: REACTOME 1.753E-4 6.416E-3 4.746E-2
1.604E-1
 4 21
26 172847 Protein digestion and absorption BioSystems: KEGG 2.098E-4 7.384E-3
5.462E-2
1.920E-1
 7 88
27 906029 Laminin interactions BioSystems: REACTOME 2.539E-4 8.603E-3
6.363E-2
2.323E-1
 4 23
28 83073 Complement and coagulation cascades BioSystems: KEGG 3.710E-4 1.212E-2
8.967E-2
3.394E-1
 6 69
29 PW:0000490 transforming growth factor-beta Smad dependent signaling Pathway Ontology 4.150E-4 1.309E-2
9.685E-2
3.797E-1
 4 26
30 PW:0000238 insulin-like growth factor signaling Pathway Ontology 5.209E-4 1.589E-2
1.175E-1
4.766E-1
 3 12
31 137963 Regulation of nuclear SMAD2/3 signaling BioSystems: Pathway Interaction Database 7.179E-4 2.119E-2
1.567E-1
6.569E-1
 6 78
32 138064 Syndecan-4-mediated signaling events BioSystems: Pathway Interaction Database 8.278E-4 2.342E-2
1.732E-1
7.574E-1
 4 31
33 645311 CS/DS degradation BioSystems: REACTOME 8.445E-4 2.342E-2
1.732E-1
7.727E-1
 3 14
34 576264 Activation of Matrix Metalloproteinases BioSystems: REACTOME 9.359E-4 2.519E-2
1.863E-1
8.564E-1
 4 32
35 169349 Validated transcriptional targets of AP1 family members Fra1 and Fra2 BioSystems: Pathway Interaction Database 1.181E-3 2.669E-2
1.974E-1
1.000E0
 4 34
36 198774 TGF-beta Receptor Signaling Pathway BioSystems: WikiPathways 1.325E-3 2.669E-2
1.974E-1
1.000E0
 8 154
37 685543 MPS IV - Morquio syndrome A BioSystems: REACTOME 1.429E-3 2.669E-2
1.974E-1
1.000E0
 7 121
38 685539 MPS IIIA - Sanfilippo syndrome A BioSystems: REACTOME 1.429E-3 2.669E-2
1.974E-1
1.000E0
 7 121
39 685540 MPS IIIB - Sanfilippo syndrome B BioSystems: REACTOME 1.429E-3 2.669E-2
1.974E-1
1.000E0
 7 121
40 685545 MPS VI - Maroteaux-Lamy syndrome BioSystems: REACTOME 1.429E-3 2.669E-2
1.974E-1
1.000E0
 7 121
41 685537 MPS I - Hurler syndrome BioSystems: REACTOME 1.429E-3 2.669E-2
1.974E-1
1.000E0
 7 121
42 685541 MPS IIIC - Sanfilippo syndrome C BioSystems: REACTOME 1.429E-3 2.669E-2
1.974E-1
1.000E0
 7 121
43 685547 MPS IX - Natowicz syndrome BioSystems: REACTOME 1.429E-3 2.669E-2
1.974E-1
1.000E0
 7 121
44 685544 MPS IV - Morquio syndrome B BioSystems: REACTOME 1.429E-3 2.669E-2
1.974E-1
1.000E0
 7 121
45 685538 MPS II - Hunter syndrome BioSystems: REACTOME 1.429E-3 2.669E-2
1.974E-1
1.000E0
 7 121
46 685546 MPS VII - Sly syndrome BioSystems: REACTOME 1.429E-3 2.669E-2
1.974E-1
1.000E0
 7 121
47 685542 MPS IIID - Sanfilippo syndrome D BioSystems: REACTOME 1.429E-3 2.669E-2
1.974E-1
1.000E0
 7 121
48 645297 Glycosaminoglycan metabolism BioSystems: REACTOME 1.429E-3 2.669E-2
1.974E-1
1.000E0
 7 121
49 685536 Mucopolysaccharidoses BioSystems: REACTOME 1.429E-3 2.669E-2
1.974E-1
1.000E0
 7 121
50 771599 Binding and Uptake of Ligands by Scavenger Receptors BioSystems: REACTOME 1.512E-3 2.767E-2
2.047E-1
1.000E0
 5 61
Show 45 more annotations

8: Pubmed [Display Chart] 35868 annotations before applied cutoff / 51853 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 20551380 Proteomics characterization of extracellular space components in the human aorta. Pubmed 1.608E-34 5.769E-30 6.383E-29 5.769E-30 23 101
2 19453261:gr High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. GeneRIF 1.173E-24 1.403E-20 1.552E-19 4.208E-20 26 383
3 19453261 High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Pubmed 1.173E-24 1.403E-20 1.552E-19 4.208E-20 26 383
4 22261194 Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury. Pubmed 4.220E-23 3.785E-19 4.187E-18 1.514E-18 15 64
5 16335952 Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. Pubmed 5.315E-15 3.813E-11 4.219E-10 1.907E-10 16 257
6 20634891:gr Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. GeneRIF 1.737E-14 8.902E-11 9.850E-10 6.231E-10 17 331
7 20634891 Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Pubmed 1.737E-14 8.902E-11 9.850E-10 6.231E-10 17 331
8 23658023 Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance. Pubmed 2.642E-13 1.185E-9 1.311E-8 9.477E-9 10 73
9 20673868:gr A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). GeneRIF 4.942E-13 1.582E-9 1.750E-8 1.773E-8 13 187
10 20673868 A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). Pubmed 4.942E-13 1.582E-9 1.750E-8 1.773E-8 13 187
11 20452482 Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. Pubmed 5.292E-13 1.582E-9 1.750E-8 1.898E-8 13 188
12 20452482:gr Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. GeneRIF 5.292E-13 1.582E-9 1.750E-8 1.898E-8 13 188
13 19578796:gr Association of genetic variants with chronic kidney disease in individuals with different lipid profiles. GeneRIF 8.754E-13 2.243E-9 2.482E-8 3.140E-8 12 152
14 19578796 Association of genetic variants with chronic kidney disease in individuals with different lipid profiles. Pubmed 8.754E-13 2.243E-9 2.482E-8 3.140E-8 12 152
15 23979707 SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers. Pubmed 4.049E-12 9.681E-9 1.071E-7 1.452E-7 11 131
16 21362503 Protein profile of exosomes from trabecular meshwork cells. Pubmed 1.546E-11 3.466E-8 3.835E-7 5.546E-7 8 49
17 20140262 Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth. Pubmed 2.349E-11 4.680E-8 5.178E-7 8.424E-7 9 79
18 20140262:gr Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth. GeneRIF 2.349E-11 4.680E-8 5.178E-7 8.424E-7 9 79
19 23154389 Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions. Pubmed 3.303E-11 6.235E-8 6.899E-7 1.185E-6 7 32
20 11311202 Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53. Pubmed 5.133E-11 9.206E-8 1.019E-6 1.841E-6 6 18
21 20628624:gr Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". GeneRIF 7.849E-11 1.036E-7 1.146E-6 2.815E-6 11 172
22 20628624 Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". Pubmed 7.849E-11 1.036E-7 1.146E-6 2.815E-6 11 172
23 19527514:gr Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants. GeneRIF 8.046E-11 1.036E-7 1.146E-6 2.886E-6 10 128
24 18818748:gr Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants. GeneRIF 8.046E-11 1.036E-7 1.146E-6 2.886E-6 10 128
25 18818748 Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants. Pubmed 8.046E-11 1.036E-7 1.146E-6 2.886E-6 10 128
26 19527514 Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants. Pubmed 8.046E-11 1.036E-7 1.146E-6 2.886E-6 10 128
27 20587546 Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection. Pubmed 8.087E-11 1.036E-7 1.146E-6 2.900E-6 7 36
28 20587546:gr Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection. GeneRIF 8.087E-11 1.036E-7 1.146E-6 2.900E-6 7 36
29 19948975:gr Integrative predictive model of coronary artery calcification in atherosclerosis. GeneRIF 1.080E-10 1.291E-7 1.429E-6 3.874E-6 12 229
30 19948975 Integrative predictive model of coronary artery calcification in atherosclerosis. Pubmed 1.080E-10 1.291E-7 1.429E-6 3.874E-6 12 229
31 19834535 Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. Pubmed 1.850E-10 2.074E-7 2.294E-6 6.635E-6 9 99
32 19834535:gr Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. GeneRIF 1.850E-10 2.074E-7 2.294E-6 6.635E-6 9 99
33 11973338:gr The epithelial mitogen keratinocyte growth factor binds to collagens via the consensus sequence glycine-proline-hydroxyproline. GeneRIF 2.062E-10 2.242E-7 2.480E-6 7.397E-6 4 4
34 2745554 SPARC, a secreted protein associated with cellular proliferation, inhibits cell spreading in vitro and exhibits Ca+2-dependent binding to the extracellular matrix. Pubmed 3.499E-10 3.692E-7 4.085E-6 1.255E-5 5 11
35 17170699 ERp57 is essential for efficient folding of glycoproteins sharing common structural domains. Pubmed 4.789E-10 4.908E-7 5.431E-6 1.718E-5 6 25
36 20485444:gr Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population. GeneRIF 7.131E-10 6.913E-7 7.649E-6 2.558E-5 9 115
37 20485444 Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population. Pubmed 7.131E-10 6.913E-7 7.649E-6 2.558E-5 9 115
38 11973338 The epithelial mitogen keratinocyte growth factor binds to collagens via the consensus sequence glycine-proline-hydroxyproline. Pubmed 1.028E-9 9.704E-7 1.074E-5 3.688E-5 4 5
39 19019335:gr Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. GeneRIF 1.500E-9 1.345E-6 1.489E-5 5.382E-5 9 125
40 19019335 Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. Pubmed 1.500E-9 1.345E-6 1.489E-5 5.382E-5 9 125
41 19182256:gr Exploring functional candidate genes for genetic association in german patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma. GeneRIF 3.075E-9 2.626E-6 2.906E-5 1.103E-4 4 6
42 19182256 Exploring functional candidate genes for genetic association in german patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma. Pubmed 3.075E-9 2.626E-6 2.906E-5 1.103E-4 4 6
43 24804215 Extracellular matrix proteins expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line. Pubmed 3.257E-9 2.717E-6 3.007E-5 1.168E-4 5 16
44 20385819 Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Pubmed 6.350E-9 5.061E-6 5.600E-5 2.278E-4 5 18
45 8900172 Type I, II, III, IV, V, and VI collagens serve as extracellular ligands for the isoforms of platelet-derived growth factor (AA, BB, and AB). Pubmed 6.350E-9 5.061E-6 5.600E-5 2.278E-4 5 18
46 19692168 Genetic susceptibility to distinct bladder cancer subphenotypes. Pubmed 1.134E-8 8.653E-6 9.575E-5 4.067E-4 13 422
47 19692168:gr Genetic susceptibility to distinct bladder cancer subphenotypes. GeneRIF 1.134E-8 8.653E-6 9.575E-5 4.067E-4 13 422
48 16289162 The identification of myocilin-associated proteins in the human trabecular meshwork. Pubmed 1.344E-8 1.004E-5 1.111E-4 4.821E-4 6 42
49 14760718 Screening for N-glycosylated proteins by liquid chromatography mass spectrometry. Pubmed 2.708E-8 1.982E-5 2.193E-4 9.712E-4 6 47
50 19625176 PTEN identified as important risk factor of chronic obstructive pulmonary disease. Pubmed 2.860E-8 2.011E-5 2.226E-4 1.026E-3 12 376
Show 45 more annotations

9: Interaction [Display Chart] 3420 annotations before applied cutoff / 16534 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:PDGFA PDGFA interactions 2.628E-12 8.989E-9 7.834E-8 8.989E-9 8 16
2 int:MMP2 MMP2 interactions 1.220E-11 2.086E-8 1.818E-7 4.173E-8 10 39
3 int:COL1A1 COL1A1 interactions 3.902E-11 4.448E-8 3.877E-7 1.335E-7 11 58
4 int:PDGFB PDGFB interactions 6.165E-11 5.226E-8 4.554E-7 2.108E-7 8 22
5 int:TGFB1 TGFB1 interactions 7.640E-11 5.226E-8 4.554E-7 2.613E-7 12 79
6 int:SPARC SPARC interactions 2.026E-10 1.155E-7 1.006E-6 6.928E-7 8 25
7 int:THBS1 THBS1 interactions 3.314E-9 1.619E-6 1.411E-5 1.133E-5 9 49
8 int:DCN DCN interactions 1.290E-7 5.516E-5 4.807E-4 4.413E-4 7 36
9 int:LGALS3 LGALS3 interactions 5.689E-7 2.162E-4 1.884E-3 1.946E-3 12 172
10 int:ACAN ACAN interactions 1.299E-6 4.442E-4 3.871E-3 4.442E-3 5 18
11 int:LGALS9 LGALS9 interactions 1.589E-6 4.940E-4 4.305E-3 5.434E-3 8 73
12 int:TGFB2 TGFB2 interactions 1.747E-6 4.978E-4 4.339E-3 5.974E-3 5 19
13 int:COL3A1 COL3A1 interactions 3.002E-6 7.896E-4 6.881E-3 1.027E-2 5 21
14 int:COL2A1 COL2A1 interactions 3.827E-6 8.238E-4 7.179E-3 1.309E-2 6 38
15 int:COL1A2 COL1A2 interactions 3.827E-6 8.238E-4 7.179E-3 1.309E-2 6 38
16 int:ITGB1 ITGB1 interactions 3.854E-6 8.238E-4 7.179E-3 1.318E-2 9 109
17 int:ELN ELN interactions 6.100E-6 1.227E-3 1.069E-2 2.086E-2 5 24
18 int:VCAN VCAN interactions 9.270E-6 1.761E-3 1.535E-2 3.170E-2 5 26
19 int:MYOC MYOC interactions 1.205E-5 2.169E-3 1.890E-2 4.121E-2 6 46
20 int:FGF7 FGF7 interactions 1.921E-5 3.010E-3 2.623E-2
6.570E-2
 4 15
21 int:FBN1 FBN1 interactions 1.921E-5 3.010E-3 2.623E-2
6.570E-2
 4 15
22 int:IGFBP3 IGFBP3 interactions 1.936E-5 3.010E-3 2.623E-2
6.622E-2
 5 30
23 int:SMAD7 SMAD7 interactions 2.263E-5 3.366E-3 2.933E-2
7.741E-2
 8 104
24 int:IGF1 IGF1 interactions 3.291E-5 4.690E-3 4.087E-2
1.126E-1
 4 17
25 int:MMP9 MMP9 interactions 3.645E-5 4.987E-3 4.346E-2
1.247E-1
 5 34
26 int:LTBP1 LTBP1 interactions 4.194E-5 5.517E-3 4.808E-2
1.434E-1
 4 18
27 int:COL6A1 COL6A1 interactions 5.266E-5 6.670E-3
5.813E-2
1.801E-1
 4 19
28 int:MAG MAG interactions 6.525E-5 7.695E-3
6.706E-2
2.231E-1
 4 20
29 int:BGN BGN interactions 6.525E-5 7.695E-3
6.706E-2
2.231E-1
 4 20
30 int:SMAD3 SMAD3 interactions 8.326E-5 9.492E-3
8.272E-2
2.847E-1
 14 372
31 int:PLG PLG interactions 9.703E-5 1.070E-2
9.329E-2
3.318E-1
 6 66
32 int:HAPLN1 HAPLN1 interactions 1.120E-4 1.164E-2
1.014E-1
3.829E-1
 3 9
33 int:NID2 NID2 interactions 1.161E-4 1.164E-2
1.014E-1
3.972E-1
 4 23
34 int:COL5A1 COL5A1 interactions 1.161E-4 1.164E-2
1.014E-1
3.972E-1
 4 23
35 int:CD44 CD44 interactions 1.245E-4 1.164E-2
1.014E-1
4.258E-1
 6 69
36 int:CCDC80 CCDC80 interactions 1.259E-4 1.164E-2
1.014E-1
4.305E-1
 2 2
37 int:ANPEP ANPEP interactions 1.259E-4 1.164E-2
1.014E-1
4.305E-1
 2 2
38 int:TGM2 TGM2 interactions 1.438E-4 1.294E-2
1.128E-1
4.916E-1
 7 101
39 int:ANTXR2 ANTXR2 interactions 1.586E-4 1.391E-2
1.212E-1
5.424E-1
 3 10
40 int:SGTA SGTA interactions 1.772E-4 1.515E-2
1.320E-1
6.060E-1
 8 139
41 int:CXCL12 CXCL12 interactions 2.163E-4 1.761E-2
1.535E-1
7.397E-1
 3 11
42 int:TGFBI TGFBI interactions 2.163E-4 1.761E-2
1.535E-1
7.397E-1
 3 11
43 int:MMP3 MMP3 interactions 2.222E-4 1.768E-2
1.540E-1
7.601E-1
 4 27
44 int:ITGB3 ITGB3 interactions 2.400E-4 1.865E-2
1.626E-1
8.208E-1
 5 50
45 int:PF4 PF4 interactions 2.860E-4 2.174E-2
1.894E-1
9.781E-1
 3 12
46 int:COL5A3 COL5A3 interactions 3.748E-4 2.671E-2
2.327E-1
1.000E0
 2 3
47 int:MMP25 MMP25 interactions 3.748E-4 2.671E-2
2.327E-1
1.000E0
 2 3
48 int:COL6A3 COL6A3 interactions 3.748E-4 2.671E-2
2.327E-1
1.000E0
 2 3
49 int:ADAM12 ADAM12 interactions 4.654E-4 3.248E-2
2.831E-1
1.000E0
 3 14
50 int:SOX10 SOX10 interactions 4.916E-4 3.363E-2
2.930E-1
1.000E0
 4 33
Show 45 more annotations

10: Cytoband [Display Chart] 176 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 7q22 7q22 6.848E-5 1.205E-2
6.931E-2
 1.205E-2 4 39

11: Transcription Factor Binding Site [Display Chart] 515 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GTGGGTGK UNKNOWN GTGGGTGK UNKNOWN 1.288E-7 6.635E-5 4.527E-4 6.635E-5 16 234
2 V$OCT1 05 V$OCT1 05 3.711E-5 9.525E-3
6.498E-2
 1.911E-2 12 213
3 V$MEF2 01 V$MEF2 01 5.548E-5 9.525E-3
6.498E-2
 2.857E-2 9 125
4 AAANWWTGC UNKNOWN AAANWWTGC UNKNOWN 1.072E-4 1.380E-2
9.417E-2
5.521E-2
 10 168
5 WGGAATGY V$TEF1 Q6 WGGAATGY V$TEF1 Q6 2.449E-4 2.214E-2
1.511E-1
1.261E-1
 13 299
6 V$RP58 01 V$RP58 01 2.579E-4 2.214E-2
1.511E-1
1.328E-1
 10 187
7 V$POU6F1 01 V$POU6F1 01 3.464E-4 2.549E-2
1.739E-1
1.784E-1
 10 194
8 V$SMAD4 Q6 V$SMAD4 Q6 4.412E-4 2.840E-2
1.938E-1
2.272E-1
 10 200
9 V$NKX25 02 V$NKX25 02 5.566E-4 2.867E-2
1.956E-1
2.867E-1
 10 206
10 V$AFP1 Q6 V$AFP1 Q6 5.566E-4 2.867E-2
1.956E-1
2.867E-1
 10 206
11 V$AMEF2 Q6 V$AMEF2 Q6 6.710E-4 3.142E-2
2.143E-1
3.456E-1
 10 211
12 V$HP1SITEFACTOR Q6 V$HP1SITEFACTOR Q6 1.207E-3 4.962E-2
3.386E-1
6.215E-1
 9 189
13 V$HMEF2 Q6 V$HMEF2 Q6 1.340E-3 4.962E-2
3.386E-1
6.900E-1
 7 120
14 WGTTNNNNNAAA UNKNOWN WGTTNNNNNAAA UNKNOWN 1.349E-3 4.962E-2
3.386E-1
6.947E-1
 15 450
Show 9 more annotations

12: Gene Family [Display Chart] 109 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 490 Collagens genenames.org 5.183E-8 5.649E-6 2.979E-5 5.649E-6 7 46
2 1065 Insulin like growth factor binding proteins genenames.org 8.398E-6 4.577E-4 2.414E-3 9.154E-4 3 6
3 626 Laminin subunits genenames.org 8.934E-5 2.435E-3 1.284E-2 9.738E-3 3 12
4 573 Small leucine rich repeat proteoglycans genenames.org 8.934E-5 2.435E-3 1.284E-2 9.738E-3 3 12
5 628 Latent transforming growth factor beta binding proteins genenames.org 3.393E-4 7.397E-3 3.900E-2 3.698E-2 2 4
6 1179 Complement system|Sushi domain containing genenames.org 9.166E-4 1.665E-2
8.781E-2
9.991E-2
 4 57
7 556 Fibulins genenames.org 1.552E-3 1.804E-2
9.511E-2
1.692E-1
 2 8
8 950 Gelsolin/villins genenames.org 1.552E-3 1.804E-2
9.511E-2
1.692E-1
 2 8
9 1278 SPARC family genenames.org 1.552E-3 1.804E-2
9.511E-2
1.692E-1
 2 8
10 1159 CD molecules|Integrin beta subunits genenames.org 1.986E-3 1.804E-2
9.511E-2
2.164E-1
 2 9
11 1234 Complement system|Endogenous ligands|C3 and PZP like, alpha-2-macroglobulin domain containing genenames.org 1.986E-3 1.804E-2
9.511E-2
2.164E-1
 2 9
12 436 Glycosyltransferase family 8 genenames.org 1.986E-3 1.804E-2
9.511E-2
2.164E-1
 2 9
13 492 Complement system genenames.org 2.538E-3 2.075E-2
1.094E-1
2.767E-1
 3 36
14 743 Short chain dehydrogenase/reductase superfamily genenames.org 2.665E-3 2.075E-2
1.094E-1
2.905E-1
 4 76
15 1250 Gla domain containing genenames.org 4.218E-3 3.065E-2
1.616E-1
4.597E-1
 2 13
Show 10 more annotations

13: Coexpression [Display Chart] 6646 annotations before applied cutoff / 21867 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M17471 Genes up-regulated in invasive ductal carcinoma (IDC) relative to ductal carcinoma in situ (DCIS, non-invasive). MSigDB C2: CGP Curated Gene Sets (v5.1) 4.014E-51 2.668E-47 2.502E-46 2.668E-47 54 351
2 M1834 Genes up-regulated in freshly isolated CD31- [GeneID=5175] (stromal stem cells from adipose tissue) versus the CD31+ (non-stem) counterparts. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.748E-42 2.242E-38 2.103E-37 4.484E-38 43 260
3 M5930 Genes defining epithelial-mesenchymal transition, as in wound healing, fibrosis and metastasis. MSigDB H: Hallmark Gene Sets (v5.1) 2.033E-39 4.504E-36 4.225E-35 1.351E-35 38 200
4 M13867 Genes up-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.829E-35 6.362E-32 5.967E-31 2.545E-31 38 256
5 M2572 Genes in the 'mesenchymal transition signature' common to all invasive cancer types. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.182E-35 6.888E-32 6.460E-31 3.444E-31 25 64
6 M13256 Genes down-regulated in mesenchymal stem cells (MSC) engineered to express EWS-FLI1 [GeneID=2130;2321] fusion protein. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.416E-34 2.677E-31 2.510E-30 1.606E-30 34 190
7 M19541 Genes commonly down-regulated in human alveolar rhabdomyosarcoma (ARMS) and its mouse model overexpressing PAX3-FOXO1 [GeneID=5077;2308] fusion. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.467E-33 2.342E-30 2.197E-29 1.639E-29 43 408
8 M2256 Genes commonly down-regulated in UET-13 cells (mesenchymal progenitor) by expression of EWSR1 [GeneID=2130] fusions with ETS transcription factors FLI1 and ERG [GeneID=2313 ,2078]. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.059E-30 2.541E-27 2.384E-26 2.033E-26 33 227
9 M13206 Genes down-regulated in TC71 and EWS502 cells (Ewing's sarcoma) by EWSR1-FLI1 [GeneID=2130;2314] as inferred from RNAi knockdown of this fusion protein. MSigDB C2: CGP Curated Gene Sets (v5.1) 7.516E-30 5.550E-27 5.205E-26 4.995E-26 37 326
10 M1804 Genes up-regulated in BT549 cells (breast cancer) by expression of SMARCE1 [GeneID=6605] off a retroviral vector. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.899E-28 1.262E-25 1.184E-24 1.262E-24 34 280
11 M4995 Genes specifically up-regulated in Cluster IIb of urothelial cell carcinom (UCC) tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.588E-28 2.168E-25 2.033E-24 2.384E-24 38 390
12 M2128 Genes up-regulated in growing IMR90 cells (fibroblast) after knockdown of RB1 [GeneID=5925] by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.169E-28 3.417E-25 3.204E-24 4.100E-24 32 243
13 M9192 Genes down-regulated in luminal-like breast cancer cell lines compared to the mesenchymal-like ones. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.759E-28 4.989E-25 4.680E-24 6.486E-24 40 460
14 M14555 Down-regulated at any timepoint following infection of primary human foreskin fibroblasts with CMV MSigDB C2: CGP Curated Gene Sets (v5.1) 1.986E-26 9.430E-24 8.845E-23 1.320E-22 25 128
15 M12225 Up-regulated genes in angioimmunoblastic lymphoma (AILT) compared to normal T lymphocytes. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.671E-25 2.513E-22 2.357E-21 3.769E-21 28 205
16 M17079 Up-regulated genes distinguishing between two subtypes of gastric cancer: advanced (AGC) and early (EGC). MSigDB C2: CGP Curated Gene Sets (v5.1) 3.238E-24 1.345E-21 1.262E-20 2.152E-20 26 175
17 M4065 Down-regulated at 24 h following infection of primary human foreskin fibroblasts with CMV MSigDB C2: CGP Curated Gene Sets (v5.1) 5.360E-24 2.095E-21 1.965E-20 3.562E-20 21 91
18 M10165 Genes up-regulated in lobular carcinoma vs normal ductal breast cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.781E-22 3.242E-19 3.041E-18 5.836E-18 18 69
19 M7514 Genes down-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [GeneID=387] off plasmid vector. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.409E-21 8.425E-19 7.902E-18 1.601E-17 32 394
20 M2122 Genes correlated with mesenchymal type of glioblastoma multiforme tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.268E-19 7.535E-17 7.067E-16 1.507E-15 24 216
21 M17923 Genes up-regulated in cultured stromal stem cells from adipose tissue, compared to the freshly isolated cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.466E-19 7.804E-17 7.319E-16 1.639E-15 31 425
22 M2259 Partial list of genes up-regulated in the kidney of GLIS2 [GeneID=84662] knockout mice compared to the wild type. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.385E-18 4.183E-16 3.923E-15 9.202E-15 17 84
23 M14507 Genes down-regulated in luminal-like breast cancer cell lines compared to the basal-like ones. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.650E-18 4.767E-16 4.471E-15 1.096E-14 31 454
24 M1521 Genes up-regulated in MMEC cells (myometrial endothelium) at 6 h after VEGFA [GeneID=7422] stimulation. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.710E-18 1.027E-15 9.635E-15 2.466E-14 15 59
25 M13547 Genes down-regulated in lobular carcinoma vs normal lobular breast cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.693E-18 1.248E-15 1.170E-14 3.119E-14 16 74
26 M1565 Genes up-regulated in MMEC cells (myometrial endothelium) by VEGFA [GeneID=7422] stimulation. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.226E-18 1.336E-15 1.253E-14 3.473E-14 18 108
27 M2293 Genes down-regulated in ES (embryonic stem cells) with defficient SUZ12 [GeneID=23512]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.173E-17 2.888E-15 2.709E-14 7.797E-14 26 315
28 M12890 Genes up-regulated in HT1080 cells (fibrosarcoma) over-expressing MMP14 [GeneID=4323] compared to those with knockdown of the gene by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.949E-17 7.001E-15 6.566E-14 1.960E-13 24 266
29 M7396 Genes down-regulated in the Kras2LA mouse lung cancer model with mutated KRAS [GeneID=3845]. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.390E-17 1.006E-14 9.435E-14 2.917E-13 29 435
30 M8901 Down-regulated genes from the 324 genes identified by two analytical methods as changed in the mammary tumors induced by transgenic expression of ERBB2 [GeneID=2064]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.096E-16 2.429E-14 2.278E-13 7.286E-13 19 149
31 M2573 Genes consistently up-regulated in mammary stem cells both in mouse and human species. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.171E-16 2.511E-14 2.355E-13 7.785E-13 30 489
32 M5929 Genes up-regulated in ANBL-6 cell line (multiple myeloma, MM) co-cultured with bone marrow stromal cells compared to those grown in the presence of IL6 [GeneID=3569]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.885E-16 3.915E-14 3.672E-13 1.253E-12 14 60
33 M3645 Genes up-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.263E-16 1.261E-13 1.183E-12 4.162E-12 28 443
34 M2506 Genes up-regulated in the neural crest stem cells (NCS), defined as p75+/HNK1+ [GeneID=4804;27087]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.325E-15 2.590E-13 2.429E-12 8.807E-12 18 146
35 M3654 Genes up-regulated in samples with systolic heart failure compared to normal hearts. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.601E-15 3.041E-13 2.852E-12 1.064E-11 27 422
36 M1610 All significantly up-regulated genes in kidney glomeruli isolated from TCF21 [Gene ID=6943] knockout mice. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.266E-15 4.086E-13 3.833E-12 1.506E-11 27 428
37 M1919 Genes up-regulated in MEF cells (embryonic fibroblast) with double knockout of the translation repressors 4EBP1 [GeneID=1978] and 4EBP2 [GeneID=1979]. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.275E-15 4.086E-13 3.833E-12 1.512E-11 25 356
38 M1484 Genes up-regulated in pancreatic cells from mice with double knockout of E2F1 [GeneID=1869] and E2F2 [GeneID=1870] compared to wild type. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.426E-15 4.242E-13 3.979E-12 1.612E-11 18 151
39 M15193 Genes up-regulated in pancreatic ductal adenocarcinoma (PDAC) identified in a meta analysis across four independent studies. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.590E-15 4.413E-13 4.139E-12 1.721E-11 25 358
40 M988 Genes up-regulated in T98G cells (glioblastoma) by TNC [GeneID=3371]. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.070E-15 5.100E-13 4.783E-12 2.040E-11 18 153
41 M2395 Genes up-regulated in pancreatic islets upon knockout of HNF1A [GeneID=6927]. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.477E-15 1.536E-12 1.441E-11 6.298E-11 18 163
42 M11788 Selected genes down-regulated during invasion of lymphatic vessels during metastasis. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.251E-14 1.979E-12 1.856E-11 8.312E-11 11 36
43 M4491 Genes down-regulated in ANBL-6 cell line (multiple myeloma, MM) expressing an activated form of NRAS [GeneID=4893] off a plasmid vector compared to those co-cultured with bone marrow stromal cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.461E-14 2.257E-12 2.117E-11 9.707E-11 15 99
44 M7883 Genes most strongly up-regulated in kidney glomeruli isolated from TCF21 [GeneID=6943] knockout mice. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.766E-14 2.667E-12 2.502E-11 1.174E-10 11 37
45 M8689 Top 200 marker genes down-regulated in the 'CTNNB1' subclass of hepatocellular carcinoma (HCC); characterized by activated CTNNB1 [GeneID=1499]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.993E-14 2.944E-12 2.761E-11 1.325E-10 18 170
46 M12004 Genes down-regulated in U2OS cells (osteosarcoma) upon knockdown of both HDAC1 and HDAC2 [GeneID=3065;3066] by RNAi. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.257E-14 4.706E-12 4.414E-11 2.165E-10 20 231
47 M9908 Genes down-regulated in preneoplastic mammary tissues and whose expression is maintained in tumors. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.587E-14 7.900E-12 7.409E-11 3.713E-10 13 70
48 M3804 Genes up-regulated in normal hematopoietic progenitors by RUNX1-RUNX1T1 [GeneID=861;862] fusion. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.776E-14 1.215E-11 1.140E-10 5.833E-10 18 185
49 M1459 Genes up-regulated in BEC (blood endothelial cells) compared to LEC (lymphatic endothelial cells). MSigDB C2: CGP Curated Gene Sets (v5.1) 1.260E-13 1.709E-11 1.603E-10 8.375E-10 17 162
50 M4737 ECM related genes up-regulated early (within 30 min) in dermal fibroblasts after addition of TGFB1 [GeneID=7040]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.346E-13 1.788E-11 1.677E-10 8.942E-10 12 58
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 3457 annotations before applied cutoff / 20974 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GSM777043 500 Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3 Immgen.org, GSE15907 3.621E-74 1.252E-70 1.092E-69 1.252E-70 75 445
2 GSM777046 500 Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4 Immgen.org, GSE15907 3.486E-73 6.025E-70 5.257E-69 1.205E-69 74 438
3 GSM777050 500 Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5 Immgen.org, GSE15907 1.099E-63 1.267E-60 1.105E-59 3.800E-60 69 467
4 GSM777055 500 Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4 Immgen.org, GSE15907 4.748E-63 4.103E-60 3.580E-59 1.641E-59 68 455
5 GSM777067 500 Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2 Immgen.org, GSE15907 2.554E-60 1.766E-57 1.541E-56 8.830E-57 66 453
6 54Dn SubClass 54Dn 1SK Top 500 All 54Dn SubClass 54Dn 1SK Top 500 All Brain Map - Allen iN 7.511E-49 4.328E-46 3.776E-45 2.597E-45 58 461
7 80Dn Top 500 All 80Dn Top 500 All Brain Map - Allen iN 4.305E-47 2.126E-44 1.855E-43 1.488E-43 58 494
8 PCBC ctl CardiacMyocyte 500 Progenitor-Cell-Biology-Consortium reference CardiacMyocyte top-relative-expression-ranked 500 PCBC 3.128E-43 1.352E-40 1.180E-39 1.082E-39 55 495
9 GSM777043 100 Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3 Immgen.org, GSE15907 3.073E-41 1.180E-38 1.030E-37 1.062E-37 32 97
10 54Dn SubClass 54Dn 1SK Top 500 Cluster 2 54Dn SubClass 54Dn 1SK Top 500 Cluster 2 Brain Map - Allen iN 8.953E-41 3.095E-38 2.700E-37 3.095E-37 43 265
11 JC fibro 1000 K1 JC fibro top-relative-expression-ranked 1000 k-means-cluster#1 PCBC 9.800E-40 3.080E-37 2.687E-36 3.388E-36 51 464
12 54Dn Top 500 All 54Dn Top 500 All Brain Map - Allen iN 2.093E-38 6.030E-36 5.262E-35 7.236E-35 51 493
13 GSM777046 100 Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4 Immgen.org, GSE15907 5.714E-36 1.519E-33 1.326E-32 1.975E-32 29 97
14 gudmap dev gonad e13.5 M InterstitTestis Sma 500 dev gonad e13.5 M InterstitTestis Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 8.033E-35 1.984E-32 1.731E-31 2.777E-31 43 362
15 endothelial SubClass DCN-hi Top 500 All endothelial SubClass DCN-hi Top 500 All Brain Map - Barres 9.236E-35 2.129E-32 1.857E-31 3.193E-31 48 495
16 PCBC ctl BronchSmoothMuscl 500 Progenitor-Cell-Biology-Consortium reference BronchSmoothMuscl top-relative-expression-ranked 500 PCBC 1.712E-32 3.698E-30 3.227E-29 5.917E-29 46 494
17 gudmap dev gonad e13.5 M InterstitFLeydig MafB k3 1000 dev gonad e13.5 M InterstitFLeydig MafB k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 2.059E-32 4.187E-30 3.654E-29 7.118E-29 40 336
18 gudmap dev gonad e11.5 M GonadVasMes Flk 500 dev gonad e11.5 M GonadVasMes Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 4.095E-32 7.864E-30 6.862E-29 1.415E-28 43 419
19 gudmap dev gonad e11.5 F GonadVasMes Flk 500 dev gonad e11.5 F GonadVasMes Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 6.754E-32 1.229E-29 1.072E-28 2.335E-28 43 424
20 gudmap dev gonad e12.5 M InterstitTestis Sma 500 dev gonad e12.5 M InterstitTestis Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 9.125E-32 1.577E-29 1.376E-28 3.155E-28 41 374
21 gudmap dev gonad e13.5 F VascAssocMesenchStromOvary MafB 500 dev gonad e13.5 F VascAssocMesenchStromOvary MafB top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 2.576E-31 4.241E-29 3.701E-28 8.906E-28 40 358
22 gudmap dev gonad e12.5 M InterstitLeydig MafB 500 dev gonad e12.5 M InterstitLeydig MafB top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 4.978E-31 7.822E-29 6.825E-28 1.721E-27 40 364
23 gudmap dev gonad e13.5 M InterstitFLeydig MafB 500 dev gonad e13.5 M InterstitFLeydig MafB top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 3.357E-30 5.045E-28 4.402E-27 1.160E-26 39 356
24 gudmap kidney adult RenalCapsule 500 kidney adult RenalCapsule top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.714E-30 5.350E-28 4.668E-27 1.284E-26 41 410
25 GSM777050 100 Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5 Immgen.org, GSE15907 6.153E-29 8.509E-27 7.424E-26 2.127E-25 24 87
26 gudmap dev gonad e13.5 F VascAssocMesenchStromOvary MafB k2 1000 dev gonad e13.5 F VascAssocMesenchStromOvary MafB k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 1.260E-28 1.675E-26 1.462E-25 4.356E-25 34 266
27 JC fibro 500 K3 JC fibro top-relative-expression-ranked 500 k-means-cluster#3 PCBC 2.230E-28 2.855E-26 2.491E-25 7.708E-25 31 206
28 ratio EB vs SC 1000 K1 ratio EmbryoidBody vs StemCell top-relative-expression-ranked 1000 k-means-cluster#1 PCBC 2.292E-26 2.829E-24 2.469E-23 7.922E-23 35 336
29 GSM777063 500 Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 2.446E-26 2.916E-24 2.545E-23 8.457E-23 39 450
30 GSM777067 100 Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2 Immgen.org, GSE15907 6.445E-26 7.427E-24 6.480E-23 2.228E-22 22 85
31 OPC Top 500 All OPC Top 500 All Brain Map - Barres 6.908E-26 7.704E-24 6.722E-23 2.388E-22 40 494
32 endothelial Top 500 All endothelial Top 500 All Brain Map - Barres 8.052E-26 8.699E-24 7.590E-23 2.784E-22 40 496
33 GSM777055 100 Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4 Immgen.org, GSE15907 8.591E-26 8.999E-24 7.852E-23 2.970E-22 22 86
34 gudmap dev gonad e12.5 M InterstitTestis Sma k4 1000 dev gonad e12.5 M InterstitTestis Sma k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 4.717E-24 4.796E-22 4.185E-21 1.631E-20 27 191
35 gudmap dev gonad e13.5 F VascAssocMesenchStromOvary Sma 500 dev gonad e13.5 F VascAssocMesenchStromOvary Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.040E-23 1.012E-21 8.827E-21 3.594E-20 34 373
36 JC fibro 500 JC fibro top-relative-expression-ranked 500 PCBC 1.054E-23 1.012E-21 8.827E-21 3.642E-20 38 497
37 GSM777059 500 Stromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 1.674E-23 1.564E-21 1.364E-20 5.786E-20 36 439
38 54Dn Top 500 Cluster 1 54Dn Top 500 Cluster 1 Brain Map - Allen iN 3.586E-23 3.263E-21 2.847E-20 1.240E-19 25 164
39 Lungmap Mouse e16.5 Myofibro Top 500 All Lungmap Mouse e16.5 Myofibro Top 500 All Lungmap Mouse Single Cell (Lungmap.net) 4.315E-23 3.825E-21 3.337E-20 1.492E-19 35 420
40 gudmap dev gonad e11.5 M GonadVasMes Flk k1 1000 dev gonad e11.5 M GonadVasMes Flk k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 7.491E-23 6.428E-21 5.608E-20 2.590E-19 32 338
41 GSM777037 500 Stromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 7.623E-23 6.428E-21 5.608E-20 2.635E-19 36 459
42 gudmap dev gonad e12.5 M InterstitLeydig MafB k1 1000 dev gonad e12.5 M InterstitLeydig MafB k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 7.910E-23 6.510E-21 5.681E-20 2.734E-19 31 311
43 gudmap kidney adult RenalCapsule k2 1000 kidney adult RenalCapsule k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.090E-22 8.762E-21 7.645E-20 3.768E-19 33 371
44 gudmap dev gonad e11.5 M GonMes Sma 500 dev gonad e11.5 M GonMes Sma top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.187E-22 9.323E-21 8.134E-20 4.102E-19 35 433
45 gudmap kidney adult RenalCapsule 200 kidney adult RenalCapsule top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 2.186E-22 1.679E-20 1.465E-19 7.557E-19 25 176
46 gudmap dev gonad e11.5 F GonadVasMes Flk k3 1000 dev gonad e11.5 F GonadVasMes Flk k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 3.399E-22 2.555E-20 2.229E-19 1.175E-18 32 355
47 gudmap dev gonad e13.5 F VascAssocMesenchStromOvary MafB k3 500 dev gonad e13.5 F VascAssocMesenchStromOvary MafB k-means-cluster#3 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 4.298E-22 3.162E-20 2.759E-19 1.486E-18 22 123
48 gudmap dev gonad e12.5 F VasAssMesen MafB 500 dev gonad e12.5 F VasAssMesen MafB top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 4.852E-22 3.444E-20 3.005E-19 1.677E-18 33 389
49 Lungmap Mouse e16.5 Matrix fibroblast Top 500 All Mouse Lung E16.5 Matrix Fibroblast top 500 Lungmap Mouse Single Cell (Lungmap.net) 4.882E-22 3.444E-20 3.005E-19 1.688E-18 34 420
50 80Dn SubClass 80Dn 1 Top 500 Cluster 0 80Dn SubClass 80Dn 1 Top 500 Cluster 0 Brain Map - Allen iN 6.461E-22 4.348E-20 3.794E-19 2.233E-18 36 489
Show 45 more annotations

15: Computational [Display Chart] 372 annotations before applied cutoff / 9399 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 module 47 Genes in module 47 MSigDb: C4 - CM: Cancer Modules 2.155E-37 8.016E-35 5.208E-34 8.016E-35 44 216
2 module 1 Genes in module 1 MSigDb: C4 - CM: Cancer Modules 1.934E-27 3.597E-25 2.337E-24 7.194E-25 44 361
3 module 2 Genes in module 2 MSigDb: C4 - CM: Cancer Modules 1.630E-23 2.021E-21 1.313E-20 6.064E-21 41 378
4 module 12 Genes in module 12 MSigDb: C4 - CM: Cancer Modules 5.533E-17 5.145E-15 3.343E-14 2.058E-14 33 351
5 module 5 Genes in module 5 MSigDb: C4 - CM: Cancer Modules 3.007E-16 2.237E-14 1.454E-13 1.119E-13 35 423
6 module 52 Genes in module 52 MSigDb: C4 - CM: Cancer Modules 1.050E-14 6.508E-13 4.229E-12 3.905E-12 33 419
7 module 6 Genes in module 6 MSigDb: C4 - CM: Cancer Modules 3.001E-14 1.595E-12 1.036E-11 1.116E-11 32 407
8 GNF2 CDH11 Neighborhood of CDH11 MSigDb: C4 - CGN: Cancer Gene Neighborhood 2.111E-12 9.817E-11 6.379E-10 7.854E-10 10 25
9 GNF2 PTX3 Neighborhood of PTX3 MSigDb: C4 - CGN: Cancer Gene Neighborhood 5.046E-12 2.035E-10 1.322E-9 1.877E-9 11 36
10 module 3 Genes in module 3 MSigDb: C4 - CM: Cancer Modules 5.470E-12 2.035E-10 1.322E-9 2.035E-9 28 375
11 module 118 Genes in module 118 MSigDb: C4 - CM: Cancer Modules 1.905E-11 6.441E-10 4.185E-9 7.085E-9 28 395
12 module 324 Genes in module 324 MSigDb: C4 - CM: Cancer Modules 2.241E-11 6.946E-10 4.513E-9 8.335E-9 17 131
13 module 122 Genes in module 122 MSigDb: C4 - CM: Cancer Modules 5.229E-11 1.496E-9 9.722E-9 1.945E-8 17 138
14 module 19 Genes in module 19 MSigDb: C4 - CM: Cancer Modules 8.397E-11 2.231E-9 1.450E-8 3.124E-8 24 307
15 module 38 Genes in module 38 MSigDb: C4 - CM: Cancer Modules 5.196E-10 1.289E-8 8.372E-8 1.933E-7 28 455
16 module 18 Genes in module 18 MSigDb: C4 - CM: Cancer Modules 4.595E-9 1.068E-7 6.942E-7 1.710E-6 26 436
17 module 513 Genes in module 513 MSigDb: C4 - CM: Cancer Modules 5.219E-8 1.142E-6 7.420E-6 1.941E-5 5 8
18 module 128 Genes in module 128 MSigDb: C4 - CM: Cancer Modules 4.034E-7 8.337E-6 5.417E-5 1.501E-4 11 98
19 module 79 Genes in module 79 MSigDb: C4 - CM: Cancer Modules 4.962E-7 9.229E-6 5.996E-5 1.846E-4 11 100
20 module 170 Genes in module 170 MSigDb: C4 - CM: Cancer Modules 4.962E-7 9.229E-6 5.996E-5 1.846E-4 11 100
21 module 24 Genes in module 24 MSigDb: C4 - CM: Cancer Modules 5.297E-7 9.383E-6 6.096E-5 1.970E-4 23 445
22 module 105 Genes in module 105 MSigDb: C4 - CM: Cancer Modules 2.439E-6 4.125E-5 2.680E-4 9.074E-4 14 194
23 module 190 Genes in module 190 MSigDb: C4 - CM: Cancer Modules 2.793E-5 4.488E-4 2.916E-3 1.039E-2 4 12
24 module 107 Genes in module 107 MSigDb: C4 - CM: Cancer Modules 2.895E-5 4.488E-4 2.916E-3 1.077E-2 8 77
25 module 44 Genes in module 44 MSigDb: C4 - CM: Cancer Modules 4.730E-5 6.954E-4 4.518E-3 1.759E-2 16 319
26 module 164 Genes in module 164 MSigDb: C4 - CM: Cancer Modules 4.860E-5 6.954E-4 4.518E-3 1.808E-2 7 61
27 module 220 Genes in module 220 MSigDb: C4 - CM: Cancer Modules 6.596E-5 9.087E-4 5.904E-3 2.454E-2 16 328
28 module 385 Genes in module 385 MSigDb: C4 - CM: Cancer Modules 7.077E-5 9.402E-4 6.109E-3 2.632E-2 5 28
29 module 474 Genes in module 474 MSigDb: C4 - CM: Cancer Modules 9.769E-5 1.253E-3 8.142E-3 3.634E-2 4 16
30 module 234 Genes in module 234 MSigDb: C4 - CM: Cancer Modules 1.849E-4 2.293E-3 1.490E-2
6.878E-2
 6 53
31 module 400 Genes in module 400 MSigDb: C4 - CM: Cancer Modules 2.004E-4 2.405E-3 1.563E-2
7.456E-2
 4 19
32 module 176 Genes in module 176 MSigDb: C4 - CM: Cancer Modules 2.693E-4 3.131E-3 2.034E-2
1.002E-1
 12 227
33 module 60 Genes in module 60 MSigDb: C4 - CM: Cancer Modules 2.792E-4 3.147E-3 2.045E-2
1.039E-1
 17 410
34 module 58 Genes in module 58 MSigDb: C4 - CM: Cancer Modules 3.019E-4 3.303E-3 2.146E-2
1.123E-1
 4 21
35 module 209 Genes in module 209 MSigDb: C4 - CM: Cancer Modules 4.294E-4 4.502E-3 2.925E-2
1.597E-1
 7 86
36 module 130 Genes in module 130 MSigDb: C4 - CM: Cancer Modules 4.357E-4 4.502E-3 2.925E-2
1.621E-1
 4 23
37 module 172 Genes in module 172 MSigDb: C4 - CM: Cancer Modules 6.900E-4 6.770E-3 4.398E-2
2.567E-1
 7 93
38 module 129 Genes in module 129 MSigDb: C4 - CM: Cancer Modules 6.915E-4 6.770E-3 4.398E-2
2.572E-1
 11 217
39 module 112 Genes in module 112 MSigDb: C4 - CM: Cancer Modules 8.215E-4 7.836E-3
5.091E-2
3.056E-1
 12 257
40 module 72 Genes in module 72 MSigDb: C4 - CM: Cancer Modules 9.116E-4 8.478E-3
5.508E-2
3.391E-1
 13 297
41 module 524 Genes in module 524 MSigDb: C4 - CM: Cancer Modules 1.236E-3 1.122E-2
7.289E-2
4.600E-1
 4 30
42 module 321 Genes in module 321 MSigDb: C4 - CM: Cancer Modules 1.666E-3 1.475E-2
9.585E-2
6.196E-1
 7 108
43 module 419 Genes in module 419 MSigDb: C4 - CM: Cancer Modules 1.992E-3 1.684E-2
1.094E-1
7.408E-1
 4 34
44 module 109 Genes in module 109 MSigDb: C4 - CM: Cancer Modules 1.992E-3 1.684E-2
1.094E-1
7.408E-1
 4 34
45 module 8 Genes in module 8 MSigDb: C4 - CM: Cancer Modules 2.057E-3 1.700E-2
1.105E-1
7.652E-1
 15 406
46 module 433 Genes in module 433 MSigDb: C4 - CM: Cancer Modules 2.611E-3 2.112E-2
1.372E-1
9.714E-1
 5 60
47 module 174 Genes in module 174 MSigDb: C4 - CM: Cancer Modules 3.454E-3 2.733E-2
1.776E-1
1.000E0
 6 92
48 module 15 Genes in module 15 MSigDb: C4 - CM: Cancer Modules 3.893E-3 3.017E-2
1.961E-1
1.000E0
 13 350
49 module 562 Genes in module 562 MSigDb: C4 - CM: Cancer Modules 4.291E-3 3.258E-2
2.117E-1
1.000E0
 3 21
50 module 280 Genes in module 280 MSigDb: C4 - CM: Cancer Modules 5.154E-3 3.835E-2
2.492E-1
1.000E0
 4 44
Show 45 more annotations

16: MicroRNA [Display Chart] 1332 annotations before applied cutoff / 19844 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-29c:miRecords TarBase hsa-miR-29c:miRecords TarBase miRecords_TarBase 2.603E-7 3.468E-4 2.695E-3 3.468E-4 5 15
2 miR-203:PicTar miR-203:PicTar PicTar 1.208E-6 8.047E-4 6.254E-3 1.609E-3 15 330
3 hsa-miR-421:TargetScan hsa-miR-421:TargetScan TargetScan 3.526E-6 1.309E-3 1.017E-2 4.696E-3 13 271
4 hsa-miR-124:miRecords TarBase hsa-miR-124:miRecords TarBase miRecords_TarBase 5.561E-6 1.309E-3 1.017E-2 7.408E-3 11 200
5 TGGTGCT,MIR-29A:MSigDB TGGTGCT,MIR-29A:MSigDB MSigDB 6.878E-6 1.309E-3 1.017E-2 9.161E-3 17 480
6 TGGTGCT,MIR-29C:MSigDB TGGTGCT,MIR-29C:MSigDB MSigDB 6.878E-6 1.309E-3 1.017E-2 9.161E-3 17 480
7 TGGTGCT,MIR-29B:MSigDB TGGTGCT,MIR-29B:MSigDB MSigDB 6.878E-6 1.309E-3 1.017E-2 9.161E-3 17 480
8 hsa-miR-29c:miRTarbase hsa-miR-29c:miRTarbase miRTarbase 1.294E-5 2.154E-3 1.674E-2 1.723E-2 5 31
9 miR-199a-star:PicTar miR-199a-star:PicTar PicTar 2.329E-5 3.447E-3 2.679E-2 3.103E-2 15 422
10 miR-144:PicTar miR-144:PicTar PicTar 3.134E-5 4.174E-3 3.244E-2 4.174E-2 15 433
11 hsa-miR-4286:mirSVR highEffct hsa-miR-4286:mirSVR nonconserved highEffect-0.5 MicroRNA.org 4.163E-5 5.041E-3 3.918E-2
5.545E-2
 14 392
12 hsa-miR-452:PITA hsa-miR-452:PITA TOP PITA 4.985E-5 5.076E-3 3.945E-2
6.640E-2
 15 451
13 AAAGGGA,MIR-211:MSigDB AAAGGGA,MIR-211:MSigDB MSigDB 5.335E-5 5.076E-3 3.945E-2
7.106E-2
 10 211
14 AAAGGGA,MIR-204:MSigDB AAAGGGA,MIR-204:MSigDB MSigDB 5.335E-5 5.076E-3 3.945E-2
7.106E-2
 10 211
15 hsa-miR-587:PITA hsa-miR-587:PITA TOP PITA 7.673E-5 5.424E-3 4.215E-2
1.022E-1
 14 415
16 hsa-miR-34c-5p:TargetScan hsa-miR-34c-5p:TargetScan TargetScan 7.737E-5 5.424E-3 4.215E-2
1.031E-1
 15 469
17 hsa-miR-449b:TargetScan hsa-miR-449b:TargetScan TargetScan 7.737E-5 5.424E-3 4.215E-2
1.031E-1
 15 469
18 hsa-miR-34a:TargetScan hsa-miR-34a:TargetScan TargetScan 7.737E-5 5.424E-3 4.215E-2
1.031E-1
 15 469
19 hsa-miR-449a:TargetScan hsa-miR-449a:TargetScan TargetScan 7.737E-5 5.424E-3 4.215E-2
1.031E-1
 15 469
20 miR-34a:PicTar miR-34a:PicTar PicTar 9.008E-5 5.999E-3 4.663E-2
1.200E-1
 13 369
21 hsa-miR-500:PITA hsa-miR-500:PITA TOP PITA 1.086E-4 6.756E-3
5.251E-2
1.446E-1
 12 325
22 miR-101:PicTar miR-101:PicTar PicTar 1.116E-4 6.756E-3
5.251E-2
1.486E-1
 14 430
23 hsa-miR-767-5p:PITA hsa-miR-767-5p:PITA TOP PITA 1.186E-4 6.871E-3
5.340E-2
1.580E-1
 11 279
24 hsa-miR-448:PITA hsa-miR-448:PITA TOP PITA 1.353E-4 7.192E-3
5.589E-2
1.802E-1
 14 438
25 ATACTGT,MIR-144:MSigDB ATACTGT,MIR-144:MSigDB MSigDB 1.429E-4 7.192E-3
5.589E-2
1.903E-1
 9 193
26 miR-369-3p:PicTar miR-369-3p:PicTar PicTar 1.441E-4 7.192E-3
5.589E-2
1.920E-1
 12 335
27 hsa-miR-370:TargetScan hsa-miR-370:TargetScan TargetScan 1.497E-4 7.192E-3
5.589E-2
1.993E-1
 10 239
28 hsa-miR-132:PITA hsa-miR-132:PITA TOP PITA 1.566E-4 7.192E-3
5.589E-2
2.086E-1
 12 338
29 hsa-miR-212:PITA hsa-miR-212:PITA TOP PITA 1.566E-4 7.192E-3
5.589E-2
2.086E-1
 12 338
30 hsa-miR-501-5p:PITA hsa-miR-501-5p:PITA TOP PITA 1.654E-4 7.343E-3
5.707E-2
2.203E-1
 12 340
31 miR-140:PicTar miR-140:PicTar PicTar 1.732E-4 7.345E-3
5.708E-2
2.307E-1
 9 198
32 hsa-miR-34c-5p:PITA hsa-miR-34c-5p:PITA TOP PITA 1.930E-4 7.345E-3
5.708E-2
2.571E-1
 11 295
33 hsa-miR-449b:PITA hsa-miR-449b:PITA TOP PITA 1.930E-4 7.345E-3
5.708E-2
2.571E-1
 11 295
34 hsa-miR-449a:PITA hsa-miR-449a:PITA TOP PITA 1.930E-4 7.345E-3
5.708E-2
2.571E-1
 11 295
35 hsa-miR-34a:PITA hsa-miR-34a:PITA TOP PITA 1.930E-4 7.345E-3
5.708E-2
2.571E-1
 11 295
36 hsa-miR-645:PITA hsa-miR-645:PITA TOP PITA 2.079E-4 7.513E-3
5.839E-2
2.770E-1
 6 85
37 miR-338:PicTar miR-338:PicTar PicTar 2.087E-4 7.513E-3
5.839E-2
2.780E-1
 9 203
38 miR-200b:PicTar miR-200b:PicTar PicTar 2.558E-4 8.930E-3
6.940E-2
3.408E-1
 14 466
39 miR-200c:PicTar miR-200c:PicTar PicTar 2.615E-4 8.930E-3
6.940E-2
3.483E-1
 14 467
40 miR-212:PicTar miR-212:PicTar PicTar 2.878E-4 9.351E-3
7.267E-2
3.834E-1
 9 212
41 miR-132:PicTar miR-132:PicTar PicTar 2.878E-4 9.351E-3
7.267E-2
3.834E-1
 9 212
42 hsa-miR-892a:PITA hsa-miR-892a:PITA TOP PITA 3.132E-4 9.500E-3
7.384E-2
4.172E-1
 10 262
43 CATTTCA,MIR-203:MSigDB CATTTCA,MIR-203:MSigDB MSigDB 3.327E-4 9.500E-3
7.384E-2
4.431E-1
 10 264
44 hsa-miR-182:PITA hsa-miR-182:PITA TOP PITA 3.377E-4 9.500E-3
7.384E-2
4.499E-1
 14 479
45 CTTTGCA,MIR-527:MSigDB CTTTGCA,MIR-527:MSigDB MSigDB 3.416E-4 9.500E-3
7.384E-2
4.550E-1
 9 217
46 hsa-miR-597:mirSVR highEffct hsa-miR-597:mirSVR nonconserved highEffect-0.5 MicroRNA.org 3.449E-4 9.500E-3
7.384E-2
4.594E-1
 14 480
47 hsa-miR-204:miRTarbase hsa-miR-204:miRTarbase miRTarbase 3.527E-4 9.500E-3
7.384E-2
4.698E-1
 4 34
48 TATTATA,MIR-374:MSigDB TATTATA,MIR-374:MSigDB MSigDB 3.531E-4 9.500E-3
7.384E-2
4.704E-1
 10 266
49 CACTGCC,MIR-34A:MSigDB CACTGCC,MIR-34A:MSigDB MSigDB 3.638E-4 9.500E-3
7.384E-2
4.845E-1
 10 267
50 CACTGCC,MIR-34C:MSigDB CACTGCC,MIR-34C:MSigDB MSigDB 3.638E-4 9.500E-3
7.384E-2
4.845E-1
 10 267
Show 45 more annotations

17: Drug [Display Chart] 27516 annotations before applied cutoff / 22098 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000024766 chondroitin sulfate Stitch 5.589E-23 1.487E-18 1.606E-17 1.538E-18 34 413
2 D017258 Medroxyprogesterone Acetate CTD 1.081E-22 1.487E-18 1.606E-17 2.975E-18 33 390
3 C488369 dasatinib CTD 4.104E-20 3.214E-16 3.471E-15 1.129E-15 33 472
4 D000069439 Dasatinib CTD 4.672E-20 3.214E-16 3.471E-15 1.285E-15 33 474
5 CID000032756 dermatan sulfate Stitch 4.192E-18 2.307E-14 2.491E-13 1.153E-13 23 220
6 D015056 1-Methyl-3-isobutylxanthine CTD 1.874E-16 8.592E-13 9.279E-12 5.155E-12 27 391
7 C010176 halofuginone CTD 1.739E-15 6.837E-12 7.383E-11 4.786E-11 17 127
8 CID000024759 hyaluronan Stitch 2.639E-15 9.075E-12 9.801E-11 7.260E-11 22 263
9 CID000104802 Rgd Peptide Stitch 4.374E-15 1.337E-11 1.444E-10 1.204E-10 21 239
10 D003994 Bucladesine CTD 5.373E-13 1.432E-9 1.546E-8 1.478E-8 21 305
11 D005944 Glucosamine CTD 5.724E-13 1.432E-9 1.546E-8 1.575E-8 21 306
12 CID005288571 AC1NRBPT Stitch 1.492E-12 3.422E-9 3.695E-8 4.106E-8 16 162
13 C487081 belinostat CTD 3.988E-12 8.441E-9 9.116E-8 1.097E-7 23 417
14 CID000002299 AC1L1DD6 Stitch 6.953E-12 1.288E-8 1.391E-7 1.913E-7 16 179
15 D014302 Trinitrobenzenesulfonic Acid CTD 7.021E-12 1.288E-8 1.391E-7 1.932E-7 22 388
16 C011559 tributyltin CTD 9.233E-12 1.588E-8 1.715E-7 2.540E-7 20 316
17 CID000001071 9-cis-retinol Stitch 1.088E-11 1.761E-8 1.901E-7 2.993E-7 21 357
18 C116926 rofecoxib CTD 2.525E-11 3.859E-8 4.168E-7 6.947E-7 13 112
19 D008769 Methylnitronitrosoguanidine CTD 2.925E-11 4.236E-8 4.575E-7 8.049E-7 18 263
20 D019808 Losartan CTD 5.283E-11 7.268E-8 7.849E-7 1.454E-6 14 145
21 D010656 Phenylephrine CTD 1.517E-10 1.987E-7 2.146E-6 4.173E-6 23 500
22 CID000003961 losartan Stitch 2.274E-10 2.844E-7 3.072E-6 6.257E-6 20 378
23 CID000006124 dimethylnitrosamine Stitch 2.922E-10 3.496E-7 3.775E-6 8.040E-6 15 196
24 D013196 Dihydrotestosterone CTD 3.880E-10 4.449E-7 4.805E-6 1.068E-5 19 348
25 C014464 3,4-dichloroaniline CTD 4.802E-10 5.285E-7 5.708E-6 1.321E-5 14 171
26 C031721 naphthalene CTD 5.133E-10 5.432E-7 5.867E-6 1.412E-5 20 396
27 CID000073587 Iamin Stitch 6.897E-10 7.029E-7 7.591E-6 1.898E-5 8 35
28 CID000001647 BAPN Stitch 7.629E-10 7.497E-7 8.096E-6 2.099E-5 10 71
29 CID000005090 rofecoxib Stitch 1.395E-9 1.323E-6 1.429E-5 3.837E-5 12 125
30 D014284 Triiodothyronine CTD 1.565E-9 1.435E-6 1.550E-5 4.305E-5 21 468
31 D002762 Cholecalciferol CTD 1.867E-9 1.657E-6 1.789E-5 5.136E-5 15 224
32 C011669 ascorbate-2-phosphate CTD 2.245E-9 1.930E-6 2.084E-5 6.176E-5 6 15
33 C500085 muraglitazar CTD 3.151E-9 2.627E-6 2.837E-5 8.669E-5 20 440
34 C506614 PD 0325901 CTD 3.660E-9 2.962E-6 3.199E-5 1.007E-4 11 108
35 C533894 LG 100815 CTD 6.536E-9 5.136E-6 5.547E-5 1.799E-4 10 88
36 C013172 gamma-oryzanol CTD 6.719E-9 5.136E-6 5.547E-5 1.849E-4 5 9
37 CID000108062 Madecassol Stitch 7.028E-9 5.227E-6 5.645E-5 1.934E-4 8 46
38 C062198 octa-2,4,6-trienoic acid CTD 7.307E-9 5.291E-6 5.714E-5 2.011E-4 10 89
39 CID000000159 prostacyclin sodium salt Stitch 8.323E-9 5.872E-6 6.342E-5 2.290E-4 15 250
40 C577942 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide CTD 9.138E-9 6.143E-6 6.634E-5 2.514E-4 7 31
41 C113580 U 0126 CTD 9.292E-9 6.143E-6 6.634E-5 2.557E-4 19 422
42 7094 DN lomustine; Down 200; 100uM; PC3; HT HG-U133A Broad Institute CMAP 9.376E-9 6.143E-6 6.634E-5 2.580E-4 13 180
43 C581572 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea CTD 1.001E-8 6.405E-6 6.917E-5 2.754E-4 8 48
44 CID000025476 Hypertensin II Stitch 1.211E-8 7.573E-6 8.178E-5 3.332E-4 19 429
45 D019319 Okadaic Acid CTD 1.271E-8 7.773E-6 8.395E-5 3.498E-4 15 258
46 CID000008534 alizarin red S Stitch 1.386E-8 8.291E-6 8.954E-5 3.814E-4 10 95
47 C583074 4,4'-hexafluorisopropylidene diphenol CTD 1.455E-8 8.507E-6 9.188E-5 4.004E-4 11 123
48 CID000000229 arabinopyranose Stitch 1.484E-8 8.507E-6 9.188E-5 4.084E-4 15 261
49 CID000094284 L-3,4-dehydroproline Stitch 1.836E-8 1.031E-5 1.114E-4 5.053E-4 9 73
50 CID000001318 1,10-phenanthroline Stitch 2.010E-8 1.092E-5 1.180E-4 5.531E-4 15 267
Show 45 more annotations

18: Disease [Display Chart] 2686 annotations before applied cutoff / 16150 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 umls:C1519670 Tumor Angiogenesis DisGeNET BeFree 2.014E-13 5.411E-10 4.584E-9 5.411E-10 28 443
2 umls:C0024796 Marfan Syndrome DisGeNET Curated 3.301E-12 4.434E-9 3.757E-8 8.867E-9 11 46
3 umls:C0268335 Ehlers-Danlos syndrome type 1 DisGeNET Curated 1.142E-9 8.435E-7 7.147E-6 3.066E-6 5 6
4 umls:C0239946 Fibrosis, Liver DisGeNET BeFree 1.256E-9 8.435E-7 7.147E-6 3.374E-6 20 327
5 umls:C0000786 Spontaneous abortion DisGeNET Curated 4.064E-9 2.183E-6 1.850E-5 1.092E-5 12 108
6 umls:C0007766 Intracranial Aneurysm DisGeNET Curated 5.884E-9 2.634E-6 2.232E-5 1.580E-5 11 89
7 umls:C0013720 Ehlers-Danlos Syndrome DisGeNET Curated 7.053E-9 2.706E-6 2.293E-5 1.894E-5 9 52
8 umls:C0017601 Glaucoma DisGeNET Curated 1.992E-8 6.688E-6 5.667E-5 5.351E-5 14 179
9 umls:C0034069 Pulmonary Fibrosis DisGeNET Curated 2.789E-8 8.324E-6 7.053E-5 7.492E-5 18 317
10 umls:C1511789 Desmoplastic DisGeNET BeFree 1.918E-7 5.151E-5 4.365E-4 5.151E-4 9 75
11 umls:C0153690 Secondary malignant neoplasm of bone DisGeNET BeFree 2.192E-7 5.352E-5 4.535E-4 5.887E-4 16 287
12 umls:C0268338 Ehlers-Danlos Syndrome, Type IV DisGeNET Curated 2.510E-7 5.618E-5 4.760E-4 6.741E-4 4 6
13 umls:C0042025 Urinary Stress Incontinence DisGeNET BeFree 3.534E-7 7.301E-5 6.187E-4 9.492E-4 5 14
14 umls:C0025286 Meningioma DisGeNET Curated 4.729E-7 7.887E-5 6.683E-4 1.270E-3 18 383
15 umls:C0022548 Keloid DisGeNET Curated 4.966E-7 7.887E-5 6.683E-4 1.334E-3 12 166
16 umls:C0029456 Osteoporosis DisGeNET Curated 4.969E-7 7.887E-5 6.683E-4 1.335E-3 16 305
17 umls:C1568363 Tendinosis DisGeNET BeFree 5.251E-7 7.887E-5 6.683E-4 1.410E-3 5 15
18 umls:C0162871 Aortic Aneurysm, Abdominal DisGeNET Curated 5.285E-7 7.887E-5 6.683E-4 1.420E-3 11 137
19 umls:C0022660 Kidney Failure, Acute DisGeNET BeFree 8.221E-7 1.162E-4 9.848E-4 2.208E-3 12 174
20 umls:C0013537 Eclampsia DisGeNET BeFree 9.861E-7 1.324E-4 1.122E-3 2.649E-3 12 177
21 umls:C1390474 Increased susceptibility to fractures DisGeNET BeFree 1.062E-6 1.351E-4 1.145E-3 2.853E-3 5 17
22 umls:C0042133 Uterine Fibroids DisGeNET Curated 1.106E-6 1.351E-4 1.145E-3 2.972E-3 16 324
23 umls:C0035309 Retinal Diseases DisGeNET Curated 1.489E-6 1.571E-4 1.331E-3 4.000E-3 15 292
24 130000 EHLERS-DANLOS SYNDROME, TYPE I OMIM 1.503E-6 1.571E-4 1.331E-3 4.038E-3 3 3
25 cv:CN202930 Ehlers-Danlos syndrome, classic type Clinical Variations 1.503E-6 1.571E-4 1.331E-3 4.038E-3 3 3
26 umls:C0079474 Hallopeau-Siemens Disease DisGeNET Curated 1.521E-6 1.571E-4 1.331E-3 4.085E-3 6 32
27 umls:C0008925 Cleft Palate DisGeNET Curated 1.957E-6 1.947E-4 1.649E-3 5.256E-3 10 126
28 umls:C0042373 Vascular Diseases DisGeNET Curated 2.602E-6 2.496E-4 2.115E-3 6.988E-3 16 346
29 umls:C1568272 Tendinopathy DisGeNET BeFree 3.364E-6 3.116E-4 2.640E-3 9.036E-3 5 21
30 umls:C0003486 Aortic Aneurysm DisGeNET Curated 5.062E-6 4.386E-4 3.716E-3 1.360E-2 12 207
31 umls:C2936349 Plaque, Amyloid DisGeNET Curated 5.062E-6 4.386E-4 3.716E-3 1.360E-2 12 207
32 umls:C0877015 Pelvic Organ Prolapse DisGeNET Curated 5.460E-6 4.515E-4 3.825E-3 1.466E-2 5 23
33 umls:C0034067 Pulmonary Emphysema DisGeNET Curated 5.547E-6 4.515E-4 3.825E-3 1.490E-2 11 174
34 umls:C0033847 Pseudoxanthoma Elasticum DisGeNET Curated 5.967E-6 4.714E-4 3.994E-3 1.603E-2 6 40
35 umls:C0162810 Cicatrix, Hypertrophic DisGeNET BeFree 7.706E-6 5.914E-4 5.011E-3 2.070E-2 7 63
36 umls:C0376634 Craniofacial Abnormalities DisGeNET Curated 9.452E-6 7.053E-4 5.976E-3 2.539E-2 11 184
37 umls:C0029434 Osteogenesis Imperfecta DisGeNET Curated 1.056E-5 7.668E-4 6.497E-3 2.837E-2 6 44
38 umls:C0008497 Choriocarcinoma DisGeNET BeFree 1.248E-5 8.823E-4 7.476E-3 3.353E-2 13 265
39 umls:C0024115 Lung diseases DisGeNET Curated 1.314E-5 9.052E-4 7.670E-3 3.530E-2 14 307
40 umls:C0023931 Lobstein's Disease DisGeNET Curated 1.478E-5 9.924E-4 8.409E-3 3.970E-2 3 5
41 umls:C0238463 Papillary thyroid carcinoma DisGeNET Curated 1.627E-5 1.066E-3 9.030E-3 4.370E-2 17 446
42 umls:C1800706 Idiopathic Pulmonary Fibrosis DisGeNET Curated 2.315E-5 1.428E-3 1.210E-2
6.219E-2
 14 323
43 umls:C0016057 Fibrosarcoma DisGeNET Curated 2.343E-5 1.428E-3 1.210E-2
6.294E-2
 12 241
44 umls:C0339573 Glaucoma, Primary Open Angle DisGeNET Curated 2.390E-5 1.428E-3 1.210E-2
6.418E-2
 10 167
45 umls:C0151744 Myocardial Ischemia DisGeNET Curated 2.392E-5 1.428E-3 1.210E-2
6.425E-2
 16 413
46 umls:C0220726 Diastrophic dysplasia DisGeNET Curated 2.558E-5 1.494E-3 1.266E-2
6.872E-2
 5 31
47 umls:C0002940 Aneurysm DisGeNET Curated 2.640E-5 1.502E-3 1.273E-2
7.091E-2
 9 135
48 umls:C0158266 Intervertebral Disc Degeneration DisGeNET Curated 2.685E-5 1.502E-3 1.273E-2
7.212E-2
 7 76
49 umls:C1704272 Benign Prostatic Hyperplasia DisGeNET BeFree 2.821E-5 1.547E-3 1.310E-2
7.578E-2
 15 373
50 umls:C0023267 Fibroid Tumor DisGeNET Curated 2.892E-5 1.554E-3 1.316E-2
7.768E-2
 13 287
Show 45 more annotations