KNOWN_TRANSITION_OMITTED(re1127)

active~TP53@nucleus - MDM2@nucleus - ARF**@nucleus - SIVA1 - HUWE1@nucleus - SIRT1@nucleus -> inactive~TP53@nucleus
center map on reaction

(center map)

Comments:

detailed description of p53 regulation beyond the scope of this map PMID:19590512 Siva1 and mdm2 PMID:15989956 HUWE1 PMID:19960022 effect of SIRT1 K382-deacetylation

In modules: