This web-page provides supplementary information:
Calzone L., Gelay A., Zinovyev A., Radvanyi F., Barillot E. A comprehensive modular map of molecular interactions in RB/E2F pathway. 2008. Molecular Systems Biology 4:174 doi:10.1038/msb.2008.7 Link
Short Abstract:
The retinoblastoma tumor suppressor protein (RB1) negatively regulates transcription by sequestering major transcription factors, the E2Fs. Here, we developed a detailed comprehensive map of some proteins and published interactions involved in the regulation of RB, along with an alternative modular diagram that we derived from the consensus network.
![](rbpathway1.gif)
You can find a list of all the people involved in the construction of the RB/E2F map [Participants]
along with the list of external contributors and their specific contributions, when available [Contributors].
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