(center map)
(1) succinyl-CoA@mitochondrial intermembrane space+glycine@mitochondrial intermembrane space - ALAS*:pyridoxal 5'-phosphate@mitochondrial intermembrane space -> 5 aminolevulinic acid@mitochondrial intermembrane space+CO_sub_2_endsub_@mitochondrial intermembrane space+coenzyme A@mitochondrial intermembrane space
(2) coproporphyrinogen III@mitochondrial intermembrane space+O_sub_2_endsub_@mitochondrial intermembrane space - CPOX@mitochondrial intermembrane space -> protoporphyrinogen@mitochondrial intermembrane space+H_sub_2_endsub_O_sub_2_endsub_@mitochondrial intermembrane space+CO_sub_2_endsub_@mitochondrial intermembrane space