(1) coproporphyrinogen III@mitochondrial intermembrane space+O_sub_2_endsub_@mitochondrial intermembrane space - CPOX@mitochondrial intermembrane space -> protoporphyrinogen@mitochondrial intermembrane space+H_sub_2_endsub_O_sub_2_endsub_@mitochondrial intermembrane space+CO_sub_2_endsub_@mitochondrial intermembrane space