4.3.4 Candidate genes

To retrieve the list of genes located in the amplified regions previously identified do the following:

1. import in the current view the human gene profile (see Figure 4.8(a)). It will will be displayed at the bottom of the main panel
2. scroll down to the bottom of the main panel
3. click on the Human gene profile
4. holding the control-key click on any other array CGH profile
5. in the Tools menu click on Tools $\rightarrow$Genome Annotation $\rightarrow$Gene Selection (see Figure 4.8(b))

A dialog box appear and set the parameters as follows (see Figure 4.8(c)):

1. for the From parameter select Region
2. for the Results parameter select HTML report and save your file in gene-list

Now you can open a new web browser window and open the HTML file gene-list.html to visualize all the genes located in the amplified regions (see Figure 4.9).

Figure 4.8: Candidate gene retrieval

[Human gene import] [Tools menu - Genome Annotations] [Genome Annotations parameters]

Figure 4.9: Gene list