(1) FOXO* - AKT*|S473_pho|T308_pho - PIM* -> FOXO*|pho|pho (2) FOXO*|pho|pho -> FOXO* (3) 14-3-3*|unk+FOXO*|pho|pho -> 14-3-3*|unk:FOXO*|pho|pho