STATE_TRANSITION(re331)

FOXO* - AKT*|S473_pho|T308_pho - PIM* -> FOXO*|pho|pho
center map on reaction (center map)
Comments:

PMID:10102273 in vitro, by Akt, phosphosites identified by mutagenesis in 293T using phosphoFOXO1 antibodies PMID:18593906 in HEK293T, by PIM1s isoform, FOXO3 phosphorylated and inactivated. Phosphomutant of FOXO3 is not phosphorylated and the expression of a reporter gene is not inhibited.


In modules: