HETERODIMER_ASSOCIATION(re733)

HSP70*+cleaved~AIFM1 -> HSP70*:cleaved~AIFM1
center map on reaction (center map)
Comments:

PMID:11533664 in vitro, HSP70 binds to AIF and inhibits its chromatin condensation activity in MEFs that are deficient for apaf1, HSP70 protects from serum withdrawal induced cell death in MEFs, HSP70 protects from cell death induced by the ectopic expression of a constitutively active AIF


In modules: