HETERODIMER_ASSOCIATION(re486)

APAF1+HSP70* -> APAF1:HSP70*
center map on reaction (center map)
Comments:

PMID:10934467 in 293, HeLa and Jurkat cells, interaction HSP70 - APAF1 in vitro, the interaction is ATP dependent HSP70 interactions competes for oligomerization and formation of the apoptosome PMID:10934466 in vitro, HSP70 blocks the recruitment of CASP9 into the apoptosome by binding to APAF1


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