TRANSCRIPTION(re126)

gPMAIP1@nucleus - active~TP53@nucleus - active~HIF1@nucleus - active~FOXO@nucleus - CTBP*@nucleus - active~E2F1@nucleus --> rPMAIP1@nucleus
center map on reaction (center map)
Comments:

PMID:14699081 in Saos-2, direct transactivation of NOXA by HIF1A during hypoxia, role of NOXA in hypoxia-induced cell death PMID:16888645 in SH-EP, in NB15 neuroblastoma cell lines expressing a FOXO3-ER fusion, upon 4OHT. PMAIP knock down protects from apoptosis PMID:12676992 in MEF by CTBP1 and CTBP2 (RT-PCR, double knocked out) PMID:14684737 in NIH3T3, by E2F1


In modules: