DISSOCIATION
DP1*:E2F1:HDAC1:SWI/SNF:pRB*__pho@nucleus - CDK6_Thr_pho:cyclin D1*:p27Kip1*@nucleus - CDK4_Thr172_pho:cyclin D1*:p27Kip1*@nucleus - CDK4:cyclin D1*:p21Cip*@nucleus - CDK6:cyclin D1*:p21Cip*@nucleus -> HDAC1@nucleus+DP1*:E2F1:SWI/SNF:pRB*__pho__pho@nucleus
(center map)
Comments:
PMID:9315635 dissociation of HDAC1 (during the G1 to S transition) PMID:10778858 PMID:11520855 PMID:7736585, PMID:9425340 weinberg CycD phosphorylates RB (ref REACTOME) PMID:9190208
In modules:
- Module: RB
- Module: p27/p21