HETERODIMER_ASSOCIATION(re675)

XIAP|S87_unk+cleaved~GSPT1 -> XIAP|S87_unk:cleaved~GSPT1
center map on reaction (center map)
Comments:

PMID:12865429 cleaved GSPT1 harbors a IAP binding motif at tis C-terminal, AKPF, related to those found in DIABLO or HTRA2 in vitro, cleaved GSPT1 and XIAP interact in HEK293, interaction between endogenous proteins in HEK293 cytoplasmic extract (S100 fraction), cleaved GSPT1 increases CYCS+ATP induced cleavage of CASP3


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