HETERODIMER_ASSOCIATION(re632)

BAD|pho+14-3-3*|unk -> 14-3-3*|unk:BAD|pho
center map on reaction (center map)
Comments:

logical re632_s2093=FALSE PMID:10837486 interaction between BAD S155 and 14-3-3 delta and epsilon PMID:8929531 in FL5.12 co-IP of mouse BAD phosphorylated and YWHAQ in FL5.12 BAD phosphorylated only on S112 or S136 still binds 14-3-3 (S to A mutants, co-IP) in FL5.12 phosphorylation and binding to 14-3-3 inhibits BAD interaction with Bcl-XL and pro-apoptotic activity PMID:12657644 in 293T, BAD YWHAE interaction, inhibited by caspase-mediated cleavage of YWHAE PMID:17979178 BAD YWHAH interaction tandem affinity purification in a complex with Raf (cited by IntAct)


In modules: