HETERODIMER_ASSOCIATION(re443)

14-3-3*|unk+BimEL*|S87_pho -> 14-3-3*|unk:BimEL*|S87_pho
center map on reaction (center map)
Comments:

PMID:16282323 in HepG3 cells, insulin activates Akt but not ERK, and induces interaction between 14-3-3 and Bim (IP). In the same cell line, BimEL S87 phosphorylation was not assessed. The authors propose that the 14-3-3 bind to Akt-phosphorylated BimEL


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