STATE_TRANSITION(re442)

BimEL* - AKT*|S473_pho|T308_pho -> BimEL*|S87_pho
center map on reaction (center map)
Comments:

PMID:16282323 in murine BA/F3 IL3-dependent cells, multisite phosphorylation of BimEL upon IL3. Attenuated by ERK and PI3K inhibitors. in vitro, active mouse Akt purified from IL3 treated BAF3 cells phosphorylates recombinant human BimEL. Blocked by mutation of S87


In modules: