HETERODIMER_ASSOCIATION(re431)

BimL*+MIF -> BimL*:MIF
center map on reaction (center map)
Comments:

PMID:18677096 From abstract (no acces to the article) interaction BIM (all 3 major isoforms) - MIF in vitro and in HEK293 and K562 immortalised human myelogenous leukaemia cell line (bcr abl positive). MIF displays negative effect on BIM mediated apoptosis when over-expressed. MIF targeting siRNA in K562 increases diamide-induced apoptosis.


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