STATE_TRANSITION(re328)

AKT* - PHLDA3 - PDPK1 - MAPKAP1:MLST8:MTOR:RICTOR -> AKT*|S473_pho|T308_pho
center map on reaction (center map)
Comments:

PMID:19203586 PHLDA3 competes with the PH domain of Akt for binding of membrane lipids, thereby inhibiting Akt translocation to the cellular membrane and activation PMID:15718470 TORC2 complex as AKT S473 kinase


In modules: