STATE_TRANSITION(re14)

BAX|S163_unk|T167_unk@mitochondrial outer membrane - BCL2L11@mitochondrial outer membrane - tBID|myr@mitochondrial outer membrane -> BAX|S163_unk|T167_unk@mitochondrial outer membrane
center map on reaction (center map)
Comments:

PMID:15486085 in FL5.12 cells correlation of BIM-BAX interaction in mitochondrial fractions with presence of unphosphorylated S65 BimEL non phosphorylatable BimEL enhanced interaction with BAX and enhanced proapoptotic activity PMID:12419244 in vitro in reconstituted vesicles, BID induces BAX and membrane permeabilization


In modules: