TRANSCRIPTION(re134)

gBAX@nucleus - active~TP53@nucleus - active~NF_kappa_B@nucleus - CTBP*@nucleus --> rBAX@nucleus
center map on reaction (center map)
Comments:

PMID:7834749 by p53 PMID:15613549 in HEK 293, by NFkB, upon expression of LMP1 protein (from EBV). More precisely, p65/p50 dimer inhibits BAX promoter activity whereas p50/p50 dimer is actually an transcriptional activator or BAX. However p65 has to be inhibited to see p50/p50 mediated activation of BAX PMID:12676992 in MEF double knocked out by CTBP1 and CTBP2 (RT-PCR)


In modules: