(center map) (center map)PMID:20308559 bioinformatic prediction in HCT116, expression of MIR107 precursor decreases ARNT protein abundance in HCT116, in Hela, in SW480, RNA antisens to MIR107 increases ARNT protein abundance + luciferase reporter assay using the 3'UTR of ARNT in HCT116, knockdown of endogenous miR-107 increased desferrioxamine(hypoxia mimick)-induced VEGF levels, which is rescued by a expression of ARNT lacking its 3'UTR. in HCT116, pre-miR-107 decreases the ability of HCT116 cells to stimulate endothelial proliferation upon hypoxia (MMT assay)