STATE_TRANSITION(re1000)

BCL2|unk@mitochondrial outer membrane - cleaved~CASP3 - FKBP8@mitochondrial outer membrane -> cleaved~BCL2@mitochondrial outer membrane
center map on reaction (center map)
Comments:

PMID:10409669 CASP3 mediated cleavage of BCL2 in vitro and in HL60 cells or MCF7 with reconstituted CASP3 expression after exposure to staurosporine no cleavage by CASP7 PMID:20139069 FKBP8 protects BCL2 from CASP3-mediated degrdation


In modules: