(center map)
(1) malate@mitochondrial matrix+NAD_super_+_endsuper_@mitochondrial matrix - MDH1@mitochondrial matrix -> oxaloacetate@mitochondrial matrix+H_super_+_endsuper_@mitochondrial matrix+NADH@mitochondrial matrix
(2) isocitrate@mitochondrial matrix+H_super_+_endsuper_@mitochondrial matrix+NADP_super_+_endsuper_@mitochondrial matrix - IDH2:Mg_super_2+_endsuper_@mitochondrial matrix -> 2-oxoglutarate@mitochondrial matrix+CO_sub_2_endsub_@mitochondrial matrix+NADPH@mitochondrial matrix
(3) 2-oxoglutarate@mitochondrial matrix+coenzyme A@mitochondrial matrix+NAD_super_+_endsuper_@mitochondrial matrix - DLD:DLST:FAD:OGDH@mitochondrial matrix -> succinyl-CoA@mitochondrial matrix+H_super_+_endsuper_@mitochondrial matrix+CO_sub_2_endsub_@mitochondrial matrix+NADH@mitochondrial matrix
(4) isocitrate@mitochondrial matrix+H_super_+_endsuper_@mitochondrial matrix+NAD_super_+_endsuper_@mitochondrial matrix - IDH3A:IDH3B:IDH3C:Mg_super_2+_endsuper_@mitochondrial matrix -> 2-oxoglutarate@mitochondrial matrix+CO_sub_2_endsub_@mitochondrial matrix+NADH@mitochondrial matrix
(5) pyruvate@mitochondrial matrix+coenzyme A@mitochondrial matrix+NAD_super_+_endsuper_@mitochondrial matrix - DLAT:DLD:FAD:PDHA1@mitochondrial matrix -> acetyl-CoA@mitochondrial matrix+NADH@mitochondrial matrix+CO_sub_2_endsub_@mitochondrial matrix+H_super_+_endsuper_@mitochondrial matrix
(6) ubiquinone@mitochondrial inner membrane+H_super_+_endsuper_@mitochondrial matrix+NADH@mitochondrial matrix - FMN:MT-ND1:MT-ND2:MT-ND3:MT-ND4:MT-ND4L:MT-ND5:MT-ND6:NDUFA1:NDUFA10:NDUFA11:NDUFA12:NDUFA13:NDUFA2:NDUFA3:NDUFA4:NDUFA5:NDUFA6:NDUFA7:NDUFA8:NDUFA9:NDUFAB1:NDUFB1:NDUFB10:NDUFB11:NDUFB2:NDUFB3:NDUFB4:NDUFB5:NDUFB6:NDUFB7:NDUFB8:NDUFB9:NDUFC1:NDUFC2:NDUFS1:NDUFS2:NDUFS3:NDUFS4:NDUFS5:NDUFS6:NDUFS7:NDUFS8:NDUFV1:NDUFV2:NDUFV3@mitochondrial inner membrane - STAT3|pho@mitochondrial inner membrane -> ubiquinol@mitochondrial inner membrane+H_super_+_endsuper_@mitochondrial intermembrane space+NAD_super_+_endsuper_@mitochondrial matrix
(7) CYCS:cardiolipin@mitochondrial inner membrane+H_super_+_endsuper_@mitochondrial matrix+ubiquinol@mitochondrial inner membrane - CYC1:MT-CYB:UCRC*:UQCR:UQCRB:UQCRC1:UQCRC2:UQCRFS1:UQCRH:UQCRQ:cleaved~UQCRFS1*@mitochondrial inner membrane -> CYCS:cardiolipin@mitochondrial inner membrane+H_super_+_endsuper_@mitochondrial intermembrane space+ubiquinone@mitochondrial inner membrane
(8) CYCS:cardiolipin@mitochondrial inner membrane+H_super_+_endsuper_@mitochondrial matrix+O_sub_2_endsub_@mitochondrial inner membrane - COX4I1:COX5A:COX5B:COX6A*:COX6B*:COX6C:COX7A*:COX7B*:COX7C:COX8*:Cu_super_2+_endsuper_:MT-CO1:MT-CO2:MT-CO3:heme a@mitochondrial inner membrane - NO@mitochondrial inner membrane - COX4I2:COX5A:COX5B:COX6A*:COX6B*:COX6C:COX7A*:COX7B*:COX7C:COX8*:Cu_super_2+_endsuper_:MT-CO1:MT-CO2:MT-CO3:heme a@mitochondrial inner membrane -> CYCS:cardiolipin@mitochondrial inner membrane+H_super_+_endsuper_@mitochondrial intermembrane space
(9) protoporphyrin IX@mitochondrial matrix+Fe_super_2+_endsuper_@mitochondrial matrix - FECH@mitochondrial matrix -> ferroheme b@mitochondrial matrix+H_super_+_endsuper_@mitochondrial matrix
(10) H_super_+_endsuper_@mitochondrial intermembrane space+ADP@mitochondrial matrix - ATP5A1:ATP5B:ATP5C1:ATP5D:ATP5E:ATP5F1:ATP5G*:ATP5H:ATP5I:ATP5J:ATP5J2:ATP5L:ATP5O:ATP5S:MT-ATP6:MT-ATP8@mitochondrial inner membrane -> H_super_+_endsuper_@mitochondrial matrix+ATP@mitochondrial matrix
(11) H_super_+_endsuper_@mitochondrial matrix+ATP@mitochondrial matrix - ATPIF1@mitochondrial inner membrane - ATP5A1:ATP5B:ATP5C1:ATP5D:ATP5E:ATP5F1:ATP5G*:ATP5H:ATP5I:ATP5J:ATP5J2:ATP5L:ATP5O:ATP5S:MT-ATP6:MT-ATP8@mitochondrial inner membrane -> H_super_+_endsuper_@mitochondrial intermembrane space+ADP@mitochondrial matrix
(12) H_super_+_endsuper_@mitochondrial intermembrane space - UCP*@mitochondrial inner membrane -t-> H_super_+_endsuper_@mitochondrial matrix