STATE_TRANSITION(re979)

ATP5A1@mitochondrial inner membrane+ATP5B@mitochondrial inner membrane+ATP5G*@mitochondrial inner membrane+ATP5C1@mitochondrial inner membrane+MT-ATP6@mitochondrial inner membrane+MT-ATP8@mitochondrial inner membrane - TMEM70@mitochondrial inner membrane - ATPAF2@mitochondrial inner membrane - ATPAF1@mitochondrial inner membrane -> ATP5A1:ATP5B:ATP5C1:ATP5D:ATP5E:ATP5F1:ATP5G*:ATP5H:ATP5I:ATP5J:ATP5J2:ATP5L:ATP5O:ATP5S:MT-ATP6:MT-ATP8@mitochondrial inner membrane
center map on reaction (center map)
Comments:

PMID:11410595 ATPAF1 role in assembly of mitochondrial ATP synthase inferred from yeast, on the basis that ATPAF1 interacts with ATP5B (Y2H) and complements the yeast mutant similar function suggested for ATPAF2 PMID:14701807 in vitro, human ATPAF2 functions as a protein chaperone PMID:14757859 a mutation found in gene ATPAF2 from a patient with mitochondrial encephalomyopathies supports the role of ATPAF2 as an ATPase assembly gene PMID:18953340 TMEM70 is involved in mitochondrial ATP synthase biogenesis

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