STATE_TRANSITION(re92)

COX4I1:COX5A:COX5B:COX6A*:COX6B*:COX6C:COX7A*:COX7B*:COX7C:COX8*:Cu_super_2+_endsuper_:MT-CO1:MT-CO2:MT-CO3:heme a@mitochondrial inner membrane+COX4I2@mitochondrial inner membrane+ATP@mitochondrial inner membrane - LONP1@mitochondrial matrix -> COX4I2:COX5A:COX5B:COX6A*:COX6B*:COX6C:COX7A*:COX7B*:COX7C:COX8*:Cu_super_2+_endsuper_:MT-CO1:MT-CO2:MT-CO3:heme a@mitochondrial inner membrane+ADP@mitochondrial inner membrane
center map on reaction (center map)
Comments:

PMID:17418790 Upon hypoxia, COX4I1 degraded by LONP1 is replaced into the COX complex by COX4I2, resulting in lower ROS generation and higher electron transport chain activity

In modules: