STATE_TRANSITION(re723)

AIFM1*@mitochondrial inner membrane - CTSL*@mitochondrial intermembrane space - CTSS@mitochondrial intermembrane space - CTSB@mitochondrial intermembrane space - CAPN1:Ca_super_2+_endsuper_@mitochondrial intermembrane space -> cleaved~AIFM1@mitochondrial intermembrane space
center map on reaction

(center map)

Comments:

PMID:15775970 AIF as an inner membrane protein that is cleaved and released into the intermembrane space upon apoptosis induction PMID:15590628 calpain 1 mediated processing PMID:15933737 cathepsins and calpain 1 PMID:11278689 flavin not necessary for apoptotic function

In modules: