STATE_TRANSITION(re248)

GPI -> GPI|pho
center map on reaction (center map)
Comments:

PMID:15637053 in human fibrosarcoma HT1080 cells, phosphorylation of GPI by CK2 decreases its enzymatic activity and (non-phosphorylatable or phospho-mimetic mutants) in HT1080, knock-down of CK2 promotes GPI activity in vitro, in HT1080 cells, phosphomimetic GPI mutant forms tetramers in vitro, CK2 triggers GPI tetramerisation PMID:11004567 in vitro CK2 mediated phosphorylation of GPI on S185 in HT1080 cells, Ser phosphorylation of GPI


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