STATE_TRANSITION(re245)

glucose+ATP - HK1 - HK2 - HK3 - GCK - glucose-6P - long-chain acyl-CoAs - BAD|unk|pho:GCK:PPP1C*:PRKAC*:WASF1@mitochondrial outer membrane -> glucose-6P+ADP
center map on reaction

(center map)

Comments:

PMID:10531306 allosterinc inhibition of HK1 by glucose 6P PMID:11078441 HK inhibition by long-chain acyl-CoAs PMID:10760476 HK inhibition by long-chain acyl-CoAs PMID:7130182 GCK inhibition by long-chain acyl-CoAs PMID:12931191 in mouse liver mitochondria GCK activation by phosphorylated BAD within a mitochondrial protein complex

In modules: