PMID:15229189 SCO1, SCO2, and COX17 act cooperatively to load MT-CO2 with copper (copper chaperones) PMID:19393246 in Hela, COX17 siRNA interferes with copper loading into MT-CO2 PMID:18458339 detailed description of COX17 mediated copper loading of SCO proteins, and interactions with the disulfide based modifications of these proteins