Results and validation of the GLAD algorithm

The GLAD algorithm provides very good results as shown in Tab 1 for both the detection of breakpoints step and the region assignment step. Our algorithm performs better than other methods on a public reference data set (Snijders et al., 2001).

Data type Breakpoints detected Status correctly assigned
simulated data 97% 98.9%
karyotyping results (Snijders et al., 2001) 100% 99.8%
manually analyzed profiles 94% status are unavailable
Tab 1: Performances of the GLAD algorithm

Philippe Hupé 2004-11-19