NETI (Network Inference)

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E. coli repressilator
MAPK cascade
Yeast glycolysis
Experimental data

Artificial data: Mitogen-activated protein kinase (MAPK) cascade

Huang CHF, Ferrell Jr JE: Ultrasensitivity in the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA, 1996, 93:10078-10083. SBML module (visit also EMBL-EBI BioModels)
Network Structure (copy and paste from JDesigner)
Model (copy and paste from JDesigner)
Exemplary Time Series used for the Inference
Idealistic time series (100 time points) generated by JDesigner were subsequently distorted by time sampling, leaving 19 time points at random time intervals, and by adding statistical noise with the noise-to-signal level: 0.05. Click on the image to download the time series.
Contact : eugene.novikov@curie.fr | Bioinformatics Home Page : http://bioinfo.curie.fr | Institut Curie Home Page : http://www.curie.fr